Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte

Immunity

Volumn 13, Issue 2, 2000, Pages 187-197

  Outram, Susan V ^a   Varas, Alberto ^a   Pepicelli, Carmen V ^b   Crompton, Tessa ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Skin Group Ontogeny   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN; LAMININ; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; HISTOPATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR GENE; SIGNAL TRANSDUCTION; THYMOCYTE;

EID: 0033712944     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)00019-4     Document Type: Article

References (34)

1. Ontogeny of fetal CD8loCD4lo thymocytes: Expression of CD44, CD25 and early expression of TcR alpha mRNA
2. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
3. Mouse CD1-specific NK1 Tcells: Development, specificity, and function
4. The thymic microenvironment
5. Dual roles for patched in sequestering and transducing Hedgehog
6. Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein
7. The MAP kinase pathway controls differentiation from double negative to double positive thymocyte
8. A transgenic T cell receptor restores thymocyte differentiation in interleukin-7 receptor α chain-deficient mice
9. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
10. Two critical periods of Sonic hedgehog signaling required for the specification of motor neuron identity
11. Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expression
12. Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog
13. Overexpression of ptc1 inhibits induction of shh target genes and prevents normal patterning in the neural tube
14. Cell fate decisions in early T cell development: Regulation by cytokine receptors and the pre-TCR
15. The world according to Hedgehog
16. Notochord repression of endodermal Sonic hedgehog permits pancreas development
17. Productive T-cell receptor β-chain gene rearrangement: Coincident regulation of cell cycle and clonality during development in vivo
18. Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development
19. Transducing Hedgehog: The story so far
20. T-cell differentiation in thymus organ cultures
21. + T cells from a common precursor
22. Restoration of early thymocyte differentiation in T-cell receptor β-chain deficient mutant mice by transmembrane signalling through CD3ε
23. Regulation of V(D)J recombination activator protein RAG-2 by phosphorylation
24. V(D)J recombination and the cell cycle
25. RAG-1-deficient mice have no mature B and T lymphocytes
26. T-cell lineage commitment and cytokine responses of thymic progenitors
27. Sonic hedgehog signaling by the Patched-Smoothened receptor complex
28. Mutations affecting segment number and polarity in Drosophila
29. Identification of a palmitic acid-modified form of human Sonic hedgehog
30. Gli proteins and Hedgehog signalling in development and cancer
31. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
32. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
33. Pleiotropic changes controlled by the pre-T-cell receptor
34. Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo