Pro-thymocyte expansion by c-kit and the common cytokine receptor γ chain is essential for repertoire formation

Immunity

Volumn 6, Issue 3, 1997, Pages 265-272

  Rodewald, Hans Reimer ^a   Ogawa, Minetaro ^a   Haller, Corinne ^a   Waskow, Claudia ^a   DiSanto, James P ^b  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW; DEVELOPMENT; GENE REARRANGEMENT; GENETIC TRANSCRIPTION; LYMPHOPOIESIS; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPLEEN; THYMOCYTE; THYMUS;

EID: 0030978529     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80329-5     Document Type: Article

References (36)

1. Anderson, G., Jenkinson, E.J., Moore, N.C., and Owen, J.J. (1993). MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus. Nature 362, 70-73.
2. Anderson, G., Moore, N.C., Owen, J.J.T., and Jenkinson, E.J. (1996). Cellular interactions in thymocyte development. Annu. Rev. Immunol. 14, 73-99.
3. lck. EMBO J. 11, 4877-4886.
4. Asamoto, H., and Mandel, T.E. (1981). Thymus in mice bearing the steel mutation: morphologic studies on fetal, neonatal, organ-cultured, and grafted fetal thymus. Lab. Invest. 45, 418-426.
5. Boyd, R.L., Tucek, C.L., Godfrey, D.I., Izon, D.J., Wilson, T.J., Davidson, N.J., Bean, A.G., Ladyman, H.M., Ritter, M.A., and Hugo, P. (1993). The thymic microenvironment. Immunol. Today 14, 445-459.
6. Cao, X., Shores, E.W., Hu-Li, J., Anver, M.R., Kelsall, B.L., Russell, S.M., Drago, J., Noguchi, M., Grinberg, A., Bloom, E.T., et al. (1995). Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain. Immunity 2, 223-238.
7. D'Adamio, L., Clayton, L.K., Awad, K.M., and Reinherz, E.L. (1992). Negative selection of thymocytes: a novel polymerase chain reaction-based molecular analysis detects requirements for macromolecular synthesis. J. Immunol. 149, 3550-3553.
8. Dennert, G., and Hyman, R. (1980). Functional Thy-1 + cells in cultures of spleen cells from nu/nu mice. Eur. J. Immunol. 10, 583-589.
9. DiSanto, J.P., Muller, W., Guy-Grand, D., Fischer, A., and Rajewsky, K. (1995). Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc. Natl. Acad. Sci. USA 92, 377-381.
10. Ehlich, A., Martin, V., Muller, W., and Rajewsky, K. (1994). Analysis of the B-cell progenitor compartment at the level of single cells. Curr. Biol. 4, 573-583.
11. Galli, S.J., Zsebo, K.M., and Geissler, E.N. (1994). The kit ligand, stem cell factor. Adv. Immunol. 55, 1-96.
12. Georgopoulos, K., Bigby, M., Wang, J.-H., Molnar, A., Wu, P., Winandy, S., and Sharpe, A. (1994). The Ikaros gene is required for the development of all lymphoid lineages. Cell 79, 143-156.
13. Gilfillan, S., Benoist, C., and Mathis, D. (1995). Mice lacking terminal deoxynucleotidyl transferase: adult mice with a fetal antigen receptor repertoire. Immunol. Rev. 148, 202-219.
14. Godfrey, D.I., Zlotnik, A., and Suda, T. (1992). Phenotypic and functional characterisation of c-kit expression during intrathymic T cell development. J. Immunol. 149, 2281-2285.
15. Ihle, J.N. (1995). Cytokine receptor signaling. Nature 377, 591-594.
16. Kronenberg, M., Siu, G., Hood, L.E., and Shastri, N. (1986). The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition. Annu. Rev. Immunol. 4, 529-591.
17. Ledbetter, J.A., and Herzenberg, L.A. (1979). Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 47, 63-90.
18. Mackarehtschian, K., Hardin, J.D., Moore, K.A., Boast, S., Goff, S.P., and Lemischka, I.R. (1995). Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 3, 147-161.
19. McNiece, I.K., Langley, K.E., and Zsebo, K.M. (1991). The role of recombinant stem cell factor in early B cell development. J. Immunol. 146, 3785-3790.
20. Nocka, K., Tan, J.C., Chiu, E., Chu, T.Y., Ray, P., Traktman, P., and Besmer, P. (1990). Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W. EMBO J. 9, 1805-1813.
21. Ohbo, K., Suda, T., Hashiyama, M., Mantani, A. Ikebe, M., Miyakawa, K., Moriyama, M., Nakamura, M., Katsuki, M., Takahashi, K., Yamamura, K., and Sugamura, K. (1996). Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor γ chain. Blood 87, 956-967.
22. Peschon, J.J., Morrissey, P.J., Grabstein, K.H., Ramsdell, F.J., Maraskovsky, E., Gliniak, B.C., Park, L.S., Siegler, S.F., Williams, D.E., Ware, C.B., Meyer, J.D., and Davison, B.L. (1994). Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 180, 1955-1960.
23. Pierres, A., Naquet, P., van Agthoven, A., Bakkhoucha, F., Denizot, F., Mishal, Z., Schmitt-Verhulst, A.M., and Pierres, M. (1984). A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones. J. Immunol. 132, 2775-2782.
24. - murine thymocytes: in vivo development kinetics and T cell receptor β chain rearrangement status. J. Exp. Med. 177, 1079-1092.
25. Rodewald, H.-R., Kretzschmar, K., Takeda, S., Hohl, C., and Dessing, M. (1994). Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization. EMBO J. 13, 4229-4240.
26. Rodewald, H.R., Kretzschmar, K., Swat, W., and Takeda, S. (1995). Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo. Immunity 3, 313-319.
27. Russell, E. (1979). Hereditary anemias of the mouse: a review for geneticists. Adv. Genetics 20, 357-459.
28. Sadlack, B., Kuhn, R., Schorle, H., Rajewsky, K., Muller, W., and Horak, I. (1994). Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and -4. Eur. J. Immunol. 24, 281-284.
29. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory).
30. Serve, H., Yee, N.S., Stella, G., Sepp-Lorenzino, L., Tan, J.C., and Besmer, P. (1995). Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells. EMBO J. 14, 473-483.
31. Shinkai, Y., Rathbun, G., Lam, K.-P., Oltz, E.M., Stewart, V., Mendelsohn, M., Charron, J., Datta, M., Young, F., Stall, A.M., and Alt, F.W. (1992). RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68, 855-867.
32. Sugamura, K., Asao, H., Kondo, M., Tanaka, N., Ishii, N., Nakamura, M., and Takeshita, T. (1995). The common γ-chain for multiple cytokine receptors. Adv. Immunol. 59, 225-277.
33. Tsuji, K., Zsebo, K.M., and Ogawa, M. (1991). Murine mast cell colony formation supported by IL-3, IL-4, and recombinant rat stem cell factor, ligand for c-kit. J. Cell. Physiol. 148, 362-369.
34. von-Freeden-Jeffry, U., Vieira, P., Lucian, L.A., McNeil, T., Burdach, S.E., and Murray, R. (1995). Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 181, 1519-1526.
35. Wu, H., Klingmuller, U., Besmer, P., and Lodish, H.F. (1995). Interaction of the erythropoietin and stem-cell-factor receptors. Nature 377, 242-246.
36. Zlotnik, A., and Moore, T.A. (1995). Cytokine production and requirements during T-cell development. Curr. Opin. Immunol. 7, 206-213.