Clonal characterization of a bipotent T cell and NK cell progenitor in the mouse fetal thymus

Journal of Immunology

Volumn 164, Issue 4, 2000, Pages 1730-1733

  Michie, Alison M ^a   Carlyle, James R ^a   Schmitt, Thomas M ^a   Ljutic, Belma ^a   Cho, Sarah ^a   Fong, Quyen ^a   Zúñiga Pflücker, Juan Carlos ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SELECTION; CELL SUBPOPULATION; FETUS; MOUSE; NATURAL KILLER CELL; NONHUMAN; ONTOGENY; PHENOTYPE; PRIORITY JOURNAL; STEM CELL; T LYMPHOCYTE; THYMUS;

EID: 0034652013     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.4.1730     Document Type: Article

References (22)

1. Peault, B., J. Khazaal, and I. L. Weissman. 1994. In vitro development of B cells and macrophages from early mouse fetal thymocytes. Eur. J. Immunol. 24:781.
2. Hattori, N., H. Kawamoto, and Y. Katsura. 1996. Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells. J. Exp. Med. 184:1901.
3. Amagai, T., M. Itoi, and Y. Kondo. 1995. Limited development capacity of the earliest embryonic murine thymus. Eur. J. Immunol. 25:757.
4. Kawamoto, H., K. Ohmura, and Y. Katsura. 1998. Presence of progenitors restricted to T, B, or myeloid lineage, but absence of multipotent stem cells, in the murine fetal thymus. J. Immunol. 161:3799.
5. Antica, M., L. Wu, K. Shortman, and R. Scollay. 1993. Intrathymic lymphoid precursor cells during fetal thymus development. J. Immunol. 151:5887.
6. Zúñiga-Pflücker, J. C., D. Jiang, and M. J. Lenardo. 1995. Requirement for TNF-α and IL-1α in fetal thymocyte commitment and differentiation. Science 268:1906.
7. Zúñiga-Pflücker, J. C., and M. J. Lenardo. 1996. Regulation of thymocyte development from immature progenitors. Curr. Opin. Immunol. 8:215.
8. Carlyle, J. R., A. M. Michie, C. Furlonger, T. Nakano, M. J. Lenardo, C. J. Paige, and J. C. Zúñiga-Pflücker. 1997. Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes. J. Exp. Med. 186:173.
9. Shortman, K., and L. Wu. 1996. Early T lymphocyte progenitors. Anna. Rev. Immunol. 14:29.
10. Godfrey, D. I., and A. Zlotnik. 1993. Control points in early T-cell development. Immunol. Today 14:547.
11. Ardavin, C., L. Wu, L. Chung-Leung, and K. Shortman. 1993. Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population. Nature 362:761.
12. Matsuzaki, Y., J. Gyotoku, M. Ogawa, S. Nishikawa, and Y. Katsura. 1993. Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation. J. Exp. Med. 178:1283.
13. Moore, T. A., and A. Zlotnik. 1995. T-cell lineage commitment and cytokine response of thymic progenitors. Blood 86:1850.
14. Carlyle, J. R., and J. C. Zúñiga-Pflücker. 1998. Requirement for the thymus in αβ T lymphocyte lineage commitment. Immunity 9:187.
15. Carlyle, J. R., A. M. Michie, S. K. Cho, and J. C. Zúñiga-Pflücker. 1998. Natural killer cell development and function precede T cell differentiation in mouse fetal thymic ontogeny. J. Immunol. 160:744.
16. + T cells. Curr. Opin. Immunol. 7:367.
17. Raulel, D. H. 1999. Development and tolerance of natural killer cells. Curr. Opin. Immunol. 11:129.
18. Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47:187.
19. Rodewald, H.-R., P. Moingeon, J. L. Lucich, C. Dosiou, P. Lopez, and E. L. Reinherz. 1992. A population of early fetal thymocytes expressing FcγRII/ III contains precursors of T lymphocytes and natural killer cells. Cell 69:139.
20. Brooks, C. G., A. Georgiou, and R. K. Jordan. 1993. The majority of immature fetal thymocytes can be induced to proliferate to IL-2 and differentiate into cells indistinguishable from mature natural killer cells. J. Immunol. 151:6645.
21. Sanchez, M. J., H. Spits, L. L. Lanier, and J. H. Phillips. 1993. Human natural killer cell committed thymocytes and their relation to the T cell lineage. J. Exp. Med. 178:1857.
22. Sanchez, M. J., M. O. Muench, M. G. Roncarolo, L. L. Lanier, and J. H. Phillips. 1994. Identification of a common T/natural killer cell progenitor in human fetal thymus. J. Exp. Med. 180:569.