메뉴 건너뛰기




Volumn 172, Issue 7, 2004, Pages 4235-4244

Thymocytes between the β-Selection and Positive Selection Checkpoints Are Nonresponsive to IL-7 as Assessed by STAT-5 Phosphorylation

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; HERMES ANTIGEN; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; RNA; STAT5 PROTEIN; T LYMPHOCYTE RECEPTOR;

EID: 1642321960     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.7.4235     Document Type: Article
Times cited : (85)

References (43)
  • 1
    • 0016611505 scopus 로고
    • On the sparse seeding of bone marrow and thymus in radiation chimaeras
    • Wallis, V. J., E. Leuchars, S. Chwalinski, and A. J. Davies. 1975. On the sparse seeding of bone marrow and thymus in radiation chimaeras. Transplantation 19:2.
    • (1975) Transplantation , vol.19 , pp. 2
    • Wallis, V.J.1    Leuchars, E.2    Chwalinski, S.3    Davies, A.J.4
  • 2
    • 0029022214 scopus 로고
    • Pathways from hematopoietic stem cells to thymocytes
    • Rodewald, H. R. 1995. Pathways from hematopoietic stem cells to thymocytes. Curr. Opin. Immunol. 7:176.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 176
    • Rodewald, H.R.1
  • 3
    • 0014113689 scopus 로고
    • Current concepts of the immunological function of the thymus
    • Miller, J. F., and D. Osoba. 1967. Current concepts of the immunological function of the thymus. Physiol. Rev. 47:437.
    • (1967) Physiol. Rev. , vol.47 , pp. 437
    • Miller, J.F.1    Osoba, D.2
  • 4
    • 0027491232 scopus 로고
    • Control points in early T-cell development
    • Godfrey, D. I., and A. Zlotnik. 1993. Control points in early T-cell development. Immunol. Today 14:547.
    • (1993) Immunol. Today , vol.14 , pp. 547
    • Godfrey, D.I.1    Zlotnik, A.2
  • 5
    • 0036776370 scopus 로고    scopus 로고
    • Regulation of thymocyte differentiation: Pre-TCR signals and β-selection
    • Michie, A. M., and J. C. Zuniga-Pflucker. 2002. Regulation of thymocyte differentiation: pre-TCR signals and β-selection. Semin. Immunol. 14:311.
    • (2002) Semin. Immunol. , vol.14 , pp. 311
    • Michie, A.M.1    Zuniga-Pflucker, J.C.2
  • 7
    • 0028426281 scopus 로고
    • T cell receptor β chain gene rearrangement and selection during thymocyte development in adult mice
    • Dudley, E. C., H. T. Petrie, L. M. Shah, M. J. Owen, and A. C. Hayday. 1994. T cell receptor β chain gene rearrangement and selection during thymocyte development in adult mice. Immunity 1:83.
    • (1994) Immunity , vol.1 , pp. 83
    • Dudley, E.C.1    Petrie, H.T.2    Shah, L.M.3    Owen, M.J.4    Hayday, A.C.5
  • 8
    • 0036831290 scopus 로고    scopus 로고
    • A positive look at double-negative thymocytes
    • Ceredig, R., and T. Rolink. 2002. A positive look at double-negative thymocytes. Nat. Rev. Immunol. 2:888.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 888
    • Ceredig, R.1    Rolink, T.2
  • 9
    • 0343289090 scopus 로고    scopus 로고
    • Regulation of thymocyte development from immature progenitors
    • Zuniga-Pflucker, J. C., and M. J. Lenardo. 1996. Regulation of thymocyte development from immature progenitors. Curr. Opin. Immunol. 8:215.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 215
    • Zuniga-Pflucker, J.C.1    Lenardo, M.J.2
  • 12
    • 0005752771 scopus 로고    scopus 로고
    • Cell-fate decisions in early T cell development: Regulation by cytokine receptors and the pre-TCR
    • Haks, M. C., M. A. Oosterwegel, B. Blom, H. M. Spits, and A. M. Kruisbeek. 1999. Cell-fate decisions in early T cell development: regulation by cytokine receptors and the pre-TCR. Semin. Immunol. 11:23.
    • (1999) Semin. Immunol. , vol.11 , pp. 23
    • Haks, M.C.1    Oosterwegel, M.A.2    Blom, B.3    Spits, H.M.4    Kruisbeek, A.M.5
  • 14
  • 17
    • 0035471754 scopus 로고    scopus 로고
    • Interleukin-7: Master regulator of peripheral T-cell homeostasis?
    • Fry, T. J., and C. L. Mackall. 2001. Interleukin-7: master regulator of peripheral T-cell homeostasis? Trends Immunol. 22:564.
    • (2001) Trends Immunol. , vol.22 , pp. 564
    • Fry, T.J.1    Mackall, C.L.2
  • 18
    • 0026531928 scopus 로고
    • Interleukin-7 expression during mouse thymus development
    • Wiles, M. V., P. Ruiz, and B. A. Imhof. 1992. Interleukin-7 expression during mouse thymus development. Eur. J. Immunol. 22:1037.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1037
    • Wiles, M.V.1    Ruiz, P.2    Imhof, B.A.3
  • 19
    • 0033136288 scopus 로고    scopus 로고
    • Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors
    • Pallard, C., A. P. Stegmann, T. van Kleffens, F. Smart, A. Venkitaraman, and H. Spits. 1999. Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 10:525.
    • (1999) Immunity , vol.10 , pp. 525
    • Pallard, C.1    Stegmann, A.P.2    Van Kleffens, T.3    Smart, F.4    Venkitaraman, A.5    Spits, H.6
  • 20
    • 0030749703 scopus 로고    scopus 로고
    • Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: Stat6 is probably not required for the effect of IL-4
    • Vella, A., T. K. Teague, J. Ihle, J. Kappler, and P. Marrack. 1997. Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4. J. Exp. Med. 186:325.
    • (1997) J. Exp. Med. , vol.186 , pp. 325
    • Vella, A.1    Teague, T.K.2    Ihle, J.3    Kappler, J.4    Marrack, P.5
  • 21
    • 0030874326 scopus 로고    scopus 로고
    • The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression
    • Von Freeden-Jeffry, U., N. Solvason, M. Howard, and R. Murray. 1997. The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity 7:147.
    • (1997) Immunity , vol.7 , pp. 147
    • Von Freeden-Jeffry, U.1    Solvason, N.2    Howard, M.3    Murray, R.4
  • 22
    • 0029018306 scopus 로고
    • Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division
    • Boise, L. H., A. J. Minn, C. H. June, T. Lindsten, and C. B. Thompson. 1995. Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division. Proc. Natl. Acad. Sci. USA 92:5491.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5491
    • Boise, L.H.1    Minn, A.J.2    June, C.H.3    Lindsten, T.4    Thompson, C.B.5
  • 23
    • 0032526586 scopus 로고    scopus 로고
    • The trophic action of IL-7 on pro-T cells: Inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways
    • Kim, K., C. K. Lee, T. J. Sayers, K. Muegge, and S. K. Durum. 1998. The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways. J. Immunol. 160:5735.
    • (1998) J. Immunol. , vol.160 , pp. 5735
    • Kim, K.1    Lee, C.K.2    Sayers, T.J.3    Muegge, K.4    Durum, S.K.5
  • 25
    • 0024362473 scopus 로고
    • Interleukin 7 (murine pre-B cell growth factor/lymphopoietin 1) stimulates thymocyte growth: Regulation by transforming growth factor β
    • Chantry, D., M. Turner, and M. Feldmann. 1989. Interleukin 7 (murine pre-B cell growth factor/lymphopoietin 1) stimulates thymocyte growth: regulation by transforming growth factor β. Eur. J. Immunol. 19:783.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 783
    • Chantry, D.1    Turner, M.2    Feldmann, M.3
  • 26
    • 0025200120 scopus 로고
    • Interleukin 7 and interleukin 4 stimulate human thymocyte growth through distinct mechanisms
    • Varma, C., D. Chantry, F. Brennan, M. Turner, F. Katz, and M. Feldmann. 1990. Interleukin 7 and interleukin 4 stimulate human thymocyte growth through distinct mechanisms. Cytokine 2:55.
    • (1990) Cytokine , vol.2 , pp. 55
    • Varma, C.1    Chantry, D.2    Brennan, F.3    Turner, M.4    Katz, F.5    Feldmann, M.6
  • 28
    • 0031587826 scopus 로고    scopus 로고
    • Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    • Akashi, K., M. Kondo, U. von Freeden-Jeffry, R. Murray, and I. L. Weissman. 1997. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89:1033.
    • (1997) Cell , vol.89 , pp. 1033
    • Akashi, K.1    Kondo, M.2    Von Freeden-Jeffry, U.3    Murray, R.4    Weissman, I.L.5
  • 29
    • 0025350049 scopus 로고
    • Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily
    • Goodwin, R. G., D. Friend, S. F. Ziegler, R. Jerzy, B. A. Falk, S. Gimpel, D. Cosman, S. K. Dower, C. J. March, A. E. Namen, et al. 1990. Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily. Cell 60:941.
    • (1990) Cell , vol.60 , pp. 941
    • Goodwin, R.G.1    Friend, D.2    Ziegler, S.F.3    Jerzy, R.4    Falk, B.A.5    Gimpel, S.6    Cosman, D.7    Dower, S.K.8    March, C.J.9    Namen, A.E.10
  • 30
    • 0029858447 scopus 로고    scopus 로고
    • Signaling by IL-2 and related cytokines: JAKs, STATs, and relationship to immunodeficiency
    • Johnston, J. A., C. M. Bacon, M. C. Riedy, and J. J. O'Shea. 1996. Signaling by IL-2 and related cytokines: JAKs, STATs, and relationship to immunodeficiency. J. Leukocyte Biol. 60:441.
    • (1996) J. Leukocyte Biol. , vol.60 , pp. 441
    • Johnston, J.A.1    Bacon, C.M.2    Riedy, M.C.3    O'Shea, J.J.4
  • 31
    • 0035006109 scopus 로고    scopus 로고
    • Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras
    • Cacalano, N. A., D. Sanden, and J. A. Johnston. 2001. Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras. Nat. Cell Biol. 3:460.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 460
    • Cacalano, N.A.1    Sanden, D.2    Johnston, J.A.3
  • 32
    • 0033037268 scopus 로고    scopus 로고
    • SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation
    • Cohney, S. J., D. Sanden, N. A. Cacalano, A. Yoshimura, A. Mui, T. S. Migone, and J. A. Johnston. 1999. SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation. Mol. Cell. Biol. 19:4980.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4980
    • Cohney, S.J.1    Sanden, D.2    Cacalano, N.A.3    Yoshimura, A.4    Mui, A.5    Migone, T.S.6    Johnston, J.A.7
  • 33
    • 0027302709 scopus 로고
    • Activation of phosphatidylinositol-3 kinase by ligation of the interleukin-7 receptor on human thymocytes
    • Dadi, H. K., and C. M. Roifman. 1993. Activation of phosphatidylinositol-3 kinase by ligation of the interleukin-7 receptor on human thymocytes. J. Clin. Invest. 92:1559.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1559
    • Dadi, H.K.1    Roifman, C.M.2
  • 34
    • 0038406498 scopus 로고    scopus 로고
    • IL-7 inhibits dexamethasone-induced apoptosis via Akt/PKB in mature, peripheral T cells
    • Sade, H., and A. Sarin. 2003. IL-7 inhibits dexamethasone-induced apoptosis via Akt/PKB in mature, peripheral T cells. Eur. J. Immunol. 33:913.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 913
    • Sade, H.1    Sarin, A.2
  • 36
    • 0035167690 scopus 로고    scopus 로고
    • Control of T cell development in vivo by subdomains within the IL-7 receptor α-chain cytoplasmic tail
    • Porter, B. O., P. Scibelli, and T. R. Malek. 2001. Control of T cell development in vivo by subdomains within the IL-7 receptor α-chain cytoplasmic tail. J. Immunol. 166:262.
    • (2001) J. Immunol. , vol.166 , pp. 262
    • Porter, B.O.1    Scibelli, P.2    Malek, T.R.3
  • 37
    • 0034689002 scopus 로고    scopus 로고
    • Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling
    • Teague, T. K., B. C. Schaefer, D. Hildeman, J. Bender, T. Mitchell, J. W. Kappler, and P. Marrack. 2000. Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling. J. Exp. Med. 191:915.
    • (2000) J. Exp. Med. , vol.191 , pp. 915
    • Teague, T.K.1    Schaefer, B.C.2    Hildeman, D.3    Bender, J.4    Mitchell, T.5    Kappler, J.W.6    Marrack, P.7
  • 39
    • 0027427713 scopus 로고
    • CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection
    • Yamashita, I., T. Nagata, T. Tada, and T. Nakayama. 1993. CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection. Int. Immunol. 5:1139.
    • (1993) Int. Immunol. , vol.5 , pp. 1139
    • Yamashita, I.1    Nagata, T.2    Tada, T.3    Nakayama, T.4
  • 41
    • 0042969051 scopus 로고    scopus 로고
    • Pre-TCR signaling regulates IL-7 receptor a expression promoting thymocyte survival at the transition from the double-negative to double-positive stage
    • Trigueros, C., K. Hozumi, B. Silva-Santos, L. Bruno, A. C. Hayday, M. J. Owen, and D. J. Pennington. 2003. Pre-TCR signaling regulates IL-7 receptor a expression promoting thymocyte survival at the transition from the double-negative to double-positive stage. Eur. J. Immunol. 33:1968.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1968
    • Trigueros, C.1    Hozumi, K.2    Silva-Santos, B.3    Bruno, L.4    Hayday, A.C.5    Owen, M.J.6    Pennington, D.J.7
  • 42
    • 0031813748 scopus 로고    scopus 로고
    • Distinct roles of the interleukin-7 receptor a chain in fetal and adult thymocyte development revealed by analysis of interleukin-7 receptor α-deficient mice
    • Crompton, T., S. V. Outram, J. Buckland, and M. J. Owen. 1998. Distinct roles of the interleukin-7 receptor a chain in fetal and adult thymocyte development revealed by analysis of interleukin-7 receptor α-deficient mice. Eur. J. Immunol. 28:1859.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 1859
    • Crompton, T.1    Outram, S.V.2    Buckland, J.3    Owen, M.J.4
  • 43
    • 0033120051 scopus 로고    scopus 로고
    • Survival of naive CD4 T cells: Roles of restricting versus selecting MHC class II and cytokine milieu
    • Boursalian, T. E., and K. Bottomly. 1999. Survival of naive CD4 T cells: roles of restricting versus selecting MHC class II and cytokine milieu. J. Immunol. 162:3795.
    • (1999) J. Immunol. , vol.162 , pp. 3795
    • Boursalian, T.E.1    Bottomly, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.