T cell fate specification and αβ/γδ lineage commitment

Current Opinion in Immunology

Volumn 13, Issue 2, 2001, Pages 219-224

  MacDonald, H R ^a   Radtke, F ^a   Wilson, A ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; B LYMPHOCYTE; CELL DIFFERENTIATION; HEMATOPOIETIC STEM CELL; MOUSE; NATURAL KILLER CELL; NONHUMAN; REVIEW; T LYMPHOCYTE;

EID: 0035314009     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(00)00207-7     Document Type: Review

References (41)

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2. + T cells from a common precursor
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9. T cell progenitors emerge earlier than B cell progenitors in the murine fetal liver
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11. Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization
12. Notch signaling: Cell fate control and signal integration in development
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14. Deficient T cell fate specification in mice with an induced inactivation of Notch1
15. B lymphopoiesis in the thymus
16. Generation of intestinal T cells from progenitors residing in gut cryptopatches
17. Role of gut cryptopatches in early extrathymic maturation of intestinal intraepithelial T cells
18. An essential role for Notch1 in the development of both thymus-independent and -dependent T cells in the gut
19. A population of early fetal thymocytes expressing FcγRII/III contains precursors of T lymphocytes and natural killer cells
20. Natural killer cell development and function precede αβ T cell differentiation in mouse fetal thymic ontogeny
21. Commitment of common T/natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay
22. Clonal characterization of a bipotent T cell and NK cell progenitor in the mouse fetal thymus
23. Identification of a common T/natural killer cell progenitor in human fetal thymus
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26. Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice
27. Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells
28. Loops, lineage, and leukemia
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30. Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages
31. αβ lineage-committed thymocytes can be rescued by the γδ T cell receptor (TCR) in the absence of TCR β chain
32. Intrathymic δ selection events in γδ cell development
33. The developmental fate of T cells is critically influenced by TCRγδ expression
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35. The αβ T cell receptor can replace the γδ receptor in the development of γδ lineage cells
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39. Unexpectedly late expression of intracellular CD3ε and TCR γδ proteins during adult thymus development
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