-
1
-
-
0032053253
-
The role of E-proteins
-
Bain, G. & Murre, C. The role of E-proteins. Semin. Immunol. 10, 143-153 (1998).
-
(1998)
Semin. Immunol.
, vol.10
, pp. 143-153
-
-
Bain, G.1
Murre, C.2
-
2
-
-
0029121271
-
Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene
-
Robb, L. et al. Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene. Proc. Natl Acad. Sci. USA 92, 7075-7079 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 7075-7079
-
-
Robb, L.1
-
3
-
-
0030581174
-
The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages
-
Porcher, C. et al. The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell 86, 47-57 (1996).
-
(1996)
Cell
, vol.86
, pp. 47-57
-
-
Porcher, C.1
-
4
-
-
0032528275
-
The SCL gene specifies haemangioblast development from early mesoderm
-
Gering, M., Rodaway, A.R., Gottgens, B., Patient, R.K. & Green, A.R. The SCL gene specifies haemangioblast development from early mesoderm. EMBO J. 17, 4029-4045 (1993).
-
(1993)
EMBO J.
, vol.17
, pp. 4029-4045
-
-
Gering, M.1
Rodaway, A.R.2
Gottgens, B.3
Patient, R.K.4
Green, A.R.5
-
5
-
-
0029346879
-
Analysis of gene expression in a complex differentiation hierarchy by global amplification of cDNA from single cells
-
Brady, G. et al. Analysis of gene expression in a complex differentiation hierarchy by global amplification of cDNA from single cells. Curr. Biol. 5, 909-922 (1995).
-
(1995)
Curr. Biol.
, vol.5
, pp. 909-922
-
-
Brady, G.1
-
6
-
-
0033135847
-
The SCL gene: From case report to critical hematopoietic regulator
-
Begley, C.G. & Green, A.R. The SCL gene: from case report to critical hematopoietic regulator. Blood 93, 2760-2770 (1999).
-
(1999)
Blood
, vol.93
, pp. 2760-2770
-
-
Begley, C.G.1
Green, A.R.2
-
7
-
-
0030999645
-
The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins
-
Wadman, I.A. et al. The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins. EMBO J. 16, 3145-3157 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 3145-3157
-
-
Wadman, I.A.1
-
8
-
-
0032541488
-
The oncogenic T cell LIM-protein Lmo2 forms part of a DNA-binding complex specifically in immature T cells
-
Grutz, G.G. et al. The oncogenic T cell LIM-protein Lmo2 forms part of a DNA-binding complex specifically in immature T cells. EMBO J. 17, 4594-4605 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 4594-4605
-
-
Grutz, G.G.1
-
9
-
-
0031724589
-
TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3
-
Ono, Y., Fukuhara, N. & Yoshie, O. TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3. Mol. Cell Biol. 18, 6939-6950 (1998).
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 6939-6950
-
-
Ono, Y.1
Fukuhara, N.2
Yoshie, O.3
-
10
-
-
0032479872
-
Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells
-
Krosl, G. et al. Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells. J. Exp. Med. 188, 439-450 (1998).
-
(1998)
J. Exp. Med.
, vol.188
, pp. 439-450
-
-
Krosl, G.1
-
11
-
-
0028348648
-
Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells
-
Hsu, H.L. Wadman, I. & Baer, R. Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells. Proc. Natl Acad. Sci. USA 91, 3181-3185 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 3181-3185
-
-
Hsu, H.L.1
Wadman, I.2
Baer, R.3
-
12
-
-
0033043388
-
Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: Parallels with E2A-deficient mice
-
Chervinsky, D.S. et al. Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice. Mol. Cell Biol. 19, 5025-5035 (1999).
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 5025-5035
-
-
Chervinsky, D.S.1
-
13
-
-
0029981648
-
Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice
-
Larson, R.C. et al. Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice. EMBO J. 15, 1021-1027 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 1021-1027
-
-
Larson, R.C.1
-
14
-
-
0029844127
-
T-cell-directed TAL-1 expression induces T-cell malignancies in transgenic mice
-
Condorelli, G.L. et al. T-cell-directed TAL-1 expression induces T-cell malignancies in transgenic mice. Cancer Res. 56, 5113-5119 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 5113-5119
-
-
Condorelli, G.L.1
-
15
-
-
0029815976
-
Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha
-
Kelliher, M.A., Seldin, D.C. & Leder, P. Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha. EMBO J. 15, 5160-5166 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 5160-5166
-
-
Kelliher, M.A.1
Seldin, D.C.2
Leder, P.3
-
16
-
-
0030921503
-
An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice
-
Aplan, P.D. et al. An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice. EMBO J. 16, 2408-2419 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 2408-2419
-
-
Aplan, P.D.1
-
17
-
-
0030752361
-
E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas
-
Bain, G. et al. E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol. Cell Biol. 17, 4782-4791 (1997).
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 4782-4791
-
-
Bain, G.1
-
18
-
-
0033568023
-
A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during αβ thymopoiesis
-
Barndt, R., Dai, M.F. & Zhuang, Y. A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during αβ thymopoiesis. J. Immunol. 163, 3331-3343 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 3331-3343
-
-
Barndt, R.1
Dai, M.F.2
Zhuang, Y.3
-
19
-
-
0033506485
-
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice
-
Kim, D., Peng, X.C. & Sun, X.H. Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice. Mol. Cell Biol. 19, 8240-8253 (1999).
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 8240-8253
-
-
Kim, D.1
Peng, X.C.2
Sun, X.H.3
-
20
-
-
0033577695
-
Disruption of αβ but not of γδ T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors
-
Blom, B. et al. Disruption of αβ but not of γδ T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors. EMBO J. 18, 2793-2802 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 2793-2802
-
-
Blom, B.1
-
21
-
-
0033119330
-
Pleiotropic changes controlled by the pre-T-cell receptor
-
von Boehmer, H. et al. Pleiotropic changes controlled by the pre-T-cell receptor. Curr. Opin. Immunol. 11, 135-142 (1999).
-
(1999)
Curr. Opin. Immunol.
, vol.11
, pp. 135-142
-
-
Von Boehmer, H.1
-
22
-
-
0025642707
-
Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity
-
Aplan, P.D. et al. Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity. Science 250, 1426-1429 (1990).
-
(1990)
Science
, vol.250
, pp. 1426-1429
-
-
Aplan, P.D.1
-
23
-
-
0027491232
-
Control points in early T-cell development
-
Godfrey, D.I. & Zlotnik, A. Control points in early T-cell development. Immunol. Today 14, 547-553 (1993).
-
(1993)
Immunol. Today
, vol.14
, pp. 547-553
-
-
Godfrey, D.I.1
Zlotnik, A.2
-
24
-
-
0027439641
-
Expression of tal-1 and GATA-binding proteins during human hematopoiesis
-
Mouthon, M.A. et al. Expression of tal-1 and GATA-binding proteins during human hematopoiesis. Blood 81, 647-455 (1993).
-
(1993)
Blood
, vol.81
, pp. 647-1455
-
-
Mouthon, M.A.1
-
25
-
-
0028123474
-
The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis
-
Kallianpur, A.R., Jordan, J.E. & Brandt, S.J. The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood 83, 1200-1208 (1994).
-
(1994)
Blood
, vol.83
, pp. 1200-1208
-
-
Kallianpur, A.R.1
Jordan, J.E.2
Brandt, S.J.3
-
26
-
-
0032578487
-
Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy
-
Elefanty, A.G. et al. Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy. Proc. Natl Acad. Sci. USA 95, 11897-11902 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 11897-11902
-
-
Elefanty, A.G.1
-
27
-
-
0032530133
-
Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis
-
Kenny, D.A., Jurata, L.W., Saga, Y. & Gill, G.N. Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis. Proc. Natl Acad. Sci. USA 95, 11257-11262 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 11257-11262
-
-
Kenny, D.A.1
Jurata, L.W.2
Saga, Y.3
Gill, G.N.4
-
28
-
-
0033214186
-
Positive selection of thymocytes: The long and winding road
-
Anderson, G., Hare, K.J. & Jenkinson, E.J. Positive selection of thymocytes: the long and winding road. Immunol. Today 20, 463-468 (1999).
-
(1999)
Immunol. Today
, vol.20
, pp. 463-468
-
-
Anderson, G.1
Hare, K.J.2
Jenkinson, E.J.3
-
29
-
-
0025931233
-
Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: Implications for B-lymphoid-cell development
-
Wilson, R.B. et al. Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development. Mol. Cell Biol. 11, 6185-6191 (1991).
-
(1991)
Mol. Cell Biol.
, vol.11
, pp. 6185-6191
-
-
Wilson, R.B.1
-
30
-
-
0033577844
-
Expression of the mouse pre-T cell receptor α gene is controlled by an upstream region containing a transcriptional enhancer
-
Reizis, B. & Leder, P. Expression of the mouse pre-T cell receptor α gene is controlled by an upstream region containing a transcriptional enhancer. J. Exp. Med. 189, 1669-1678 (1999).
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1669-1678
-
-
Reizis, B.1
Leder, P.2
-
31
-
-
0027237711
-
A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines
-
Sawada, S. & Littman, D.R. A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines. Mol. Cell Biol. 13, 5620-5628 (1993).
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 5620-5628
-
-
Sawada, S.1
Littman, D.R.2
-
32
-
-
0032745697
-
Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros
-
Winandy, S., Wu, L., Wang, J.H. & Georgopoulos, K. Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros. J. Exp. Med. 190, 1039-1048 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1039-1048
-
-
Winandy, S.1
Wu, L.2
Wang, J.H.3
Georgopoulos, K.4
-
33
-
-
0032494156
-
p56lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function
-
Henning, S.W. & Cantrell, D.A. p56lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function. J. Exp. Med. 188, 931-939 (1998).
-
(1998)
J. Exp. Med.
, vol.188
, pp. 931-939
-
-
Henning, S.W.1
Cantrell, D.A.2
-
34
-
-
0033579803
-
Positive and negative regulation of V(D)J recombination by the E2A proteins
-
Bain, G., Romanow, W.J., Albers, K., Havran, W.L. & Murre, C. Positive and negative regulation of V(D)J recombination by the E2A proteins. J. Exp. Med. 189, 289-300 (1999).
-
(1999)
J. Exp. Med.
, vol.189
, pp. 289-300
-
-
Bain, G.1
Romanow, W.J.2
Albers, K.3
Havran, W.L.4
Murre, C.5
-
35
-
-
0032764978
-
Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages
-
Morrow, M.A., Mayer, E.W. Perez, C.A., Adlam, M. & Siu, G. Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages. Mol. Immunol. 36, 491-503 (1999).
-
(1999)
Mol. Immunol.
, vol.36
, pp. 491-503
-
-
Morrow, M.A.1
Mayer, E.W.2
Perez, C.A.3
Adlam, M.4
Siu, G.5
-
36
-
-
0344348920
-
Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice
-
Smith, K.S., Rhee, J.W., Naumovski, L. & Cleary, M.L. Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice. Mol. Cell Biol. 19, 4443-4451 (1999).
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 4443-4451
-
-
Smith, K.S.1
Rhee, J.W.2
Naumovski, L.3
Cleary, M.L.4
-
37
-
-
0030658039
-
Oncogenic transcription factors in the human acute leukemias
-
Look, A.T. Oncogenic transcription factors in the human acute leukemias. Science 278, 1059-1064 (1997).
-
(1997)
Science
, vol.278
, pp. 1059-1064
-
-
Look, A.T.1
-
38
-
-
0034724344
-
The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene
-
Wang, J. et al. The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene. Proc. Natl Acad. Sci. USA 97, 3497-3502 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 3497-3502
-
-
Wang, J.1
-
39
-
-
0028168862
-
1 progression by E2A and Id helix-loop-helix proteins
-
1 progression by E2A and Id helix-loop-helix proteins. EMBO J. 13, 4291-4301 (1994).
-
(1994)
EMBO J.
, vol.13
, pp. 4291-4301
-
-
Peverali, F.A.1
-
40
-
-
0030879868
-
Regulation of the expression of cyclin-dependent kinase inhibitor pit by E2A and Id proteins
-
Prabhu, S., Ignatova, A., Park, S.T. & Sun, X.H. Regulation of the expression of cyclin-dependent kinase inhibitor pit by E2A and Id proteins. Mol. Cell Biol. 17, 5888-5896 (1997).
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 5888-5896
-
-
Prabhu, S.1
Ignatova, A.2
Park, S.T.3
Sun, X.H.4
-
41
-
-
0026728357
-
Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma
-
McGuire, E.A., Rintoul, C.E., Sclar, G.M. & Korsmeyer, S.J. Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma. Mol. Cell Biol. 12, 4186-4196 (1992).
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 4186-4196
-
-
McGuire, E.A.1
Rintoul, C.E.2
Sclar, G.M.3
Korsmeyer, S.J.4
-
42
-
-
0029896451
-
B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes. E2A, E2-2, and HEB
-
Zhuang, Y., Cheng, P. & Weintraub, H. B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes. E2A, E2-2, and HEB. Mol. Cell Biol. 16, 2898-2905 (1996).
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 2898-2905
-
-
Zhuang, Y.1
Cheng, P.2
Weintraub, H.3
-
44
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate phenol-chloroform extraction
-
Chomczynski, P. & Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate phenol-chloroform extraction. Anal. Biochem. 162, 156-159 (1987).
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
45
-
-
0024002556
-
Luciferase reporter gene vectors for analysis of promoters and enhancers
-
Nordeen, S.K. Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6, 454-458 (1988).
-
(1988)
Biotechniques
, vol.6
, pp. 454-458
-
-
Nordeen, S.K.1
-
46
-
-
0033152430
-
A developmental switch from TCRδ enhancer to TCRa enhancer function during thymocyte maturation
-
Hernandez-Munain, C., Sleckman, B.P. & Krangel, M.S. A developmental switch from TCRδ enhancer to TCRa enhancer function during thymocyte maturation. Immunity 10, 723-733 (1999).
-
(1999)
Immunity
, vol.10
, pp. 723-733
-
-
Hernandez-Munain, C.1
Sleckman, B.P.2
Krangel, M.S.3
-
47
-
-
0025258473
-
The SCL gene is formed from a transcriptionally complex locus
-
Aplan, P.D. et al. The SCL gene is formed from a transcriptionally complex locus. Mol. Cell Biol. 10, 6426-6435 (1990).
-
(1990)
Mol. Cell Biol.
, vol.10
, pp. 6426-6435
-
-
Aplan, P.D.1
-
48
-
-
0028804743
-
Molecular characterization of a chromosome translocation breakpoint t(11;14)(p13;q11) from the cell line KOPT-K1
-
Dong, W.F. et al. Molecular characterization of a chromosome translocation breakpoint t(11;14)(p13;q11) from the cell line KOPT-K1. Leukemia 9, 1812-1817 (1995).
-
(1995)
Leukemia
, vol.9
, pp. 1812-1817
-
-
Dong, W.F.1
-
49
-
-
0025292710
-
Pan: A transcriptional regulator that binds chymotrypsin, insulin, and AP-4 enhancer motifs
-
Nelson, C., Shen, L.P., Meister, A., Fodor, E. & Rutter, W.J. Pan: a transcriptional regulator that binds chymotrypsin, insulin, and AP-4 enhancer motifs. Genes Dev. 4, 1035-1043 (1990).
-
(1990)
Genes Dev.
, vol.4
, pp. 1035-1043
-
-
Nelson, C.1
Shen, L.P.2
Meister, A.3
Fodor, E.4
Rutter, W.J.5
-
50
-
-
0028385758
-
Versatile retroviral vectors for potential use in gene therapy
-
Hawley, R.G., Lieu, F.H., Fong, A.Z. & Hawley, T.S. Versatile retroviral vectors for potential use in gene therapy. Gene Ther. 1, 136-138 (1994).
-
(1994)
Gene Ther.
, vol.1
, pp. 136-138
-
-
Hawley, R.G.1
Lieu, F.H.2
Fong, A.Z.3
Hawley, T.S.4
|