Early thymocyte development is regulated by modulation of E2A protein activity

Journal of Experimental Medicine

Volumn 194, Issue 6, 2001, Pages 733-745

  Engel, I ^a   Johns, C ^a   Bain, G ^a   Rivera, R R ^a   Murre, C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

selection; E2A; Id; T cell commitment; Thymocyte

Indexed keywords

DNA; HERMES ANTIGEN; INTERLEUKIN 2 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; RNA; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; DNA BINDING; ELECTROPHORETIC MOBILITY; GENE; IMMUNOBLOTTING; LYMPHOCYTE DIFFERENTIATION; MOUSE; NEWBORN; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; THYMOCYTE;

ANIMALS; ANTIGENS, CD8; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINEAGE; DNA; DNA-BINDING PROTEINS; HELIX-LOOP-HELIX MOTIFS; HOMEODOMAIN PROTEINS; MICE; MICE, KNOCKOUT; MICE, SCID; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TCF TRANSCRIPTION FACTORS; THYMUS GLAND; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035903286     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.6.733     Document Type: Article

References (46)

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5. The helixloop-helix gene E2A is required for B cell formation
6. Both E12 and E47 allow commitment to the B cell lineage
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