Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision

International Immunology

Volumn 14, Issue 6, 2002, Pages 637-645

  Han, Hua ^a   Tanigaki, Kenji ^a   Yamamoto, Norio ^a   Kuroda, Kazuki ^a   Yoshimoto, Momoko ^a   Nakahata, Tatsutoshi ^a   Ikuta, Koichi ^a   Honjo, Tasuku ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Gene targeting; Notch; RBP J; T lymphocyte

Indexed keywords

CELL SURFACE RECEPTOR; DEOXYGUANOSINE; DNA BINDING PROTEIN; GAMMA INTERFERON; NOTCH RECEPTOR; POLYINOSINIC POLYCYTIDYLIC ACID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RBPJ; UNCLASSIFIED DRUG; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE BINDING PROTEIN; MEMBRANE PROTEIN; NUCLEAR PROTEIN; RBPSUH PROTEIN, MOUSE;

ALLELE; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL ASSAY; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; EXON; GENE DELETION; GENE INACTIVATION; GENE INDUCTION; GENE MUTATION; KNOCKOUT GENE; KNOCKOUT MOUSE; LYMPHOID CELL; MATING; MOUSE; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; STEM CELL; T LYMPHOCYTE; THYMUS; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE; ANIMAL; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CLONOGENIC ASSAY; CYTOLOGY; GENETICS; HEMATOPOIETIC STEM CELL; IMMUNOLOGY; IN VITRO STUDY; LYMPHOPOIESIS; METABOLISM; MOUSE MUTANT; SIGNAL TRANSDUCTION;

ANIMALS; B-LYMPHOCYTES; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; COLONY-FORMING UNITS ASSAY; DNA-BINDING PROTEINS; HEMATOPOIETIC STEM CELLS; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; LYMPHOPOIESIS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NUCLEAR PROTEINS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0035988246     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxf030     Document Type: Article

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