Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation

EMBO Journal

Volumn 16, Issue 11, 1997, Pages 3303-3311

  Torkelson, Joel ^a,b   Harris, Reuben S ^a,b   Lombardo, Mary Jane ^a,b   Nagendran, Jayan ^a   Thulin, Carl ^a   Rosenberg, Susan M ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Adaptive mutation; Directed mutation; Evolution; Recombination; Stationary phase

Indexed keywords

ADAPTATION; ARTICLE; CELL DIFFERENTIATION; CELL SUBPOPULATION; CONTROLLED STUDY; ESCHERICHIA COLI; EVOLUTION; GENE MUTATION; GENETIC RECOMBINATION; GENETIC SELECTION; MUTAGENESIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; REPLICON; REVERTANT; SOMATIC MUTATION;

ADAPTATION, BIOLOGICAL; BASE SEQUENCE; CHROMOSOMES, BACTERIAL; ESCHERICHIA COLI; EVOLUTION; F FACTOR; GENOME, BACTERIAL; LAC OPERON; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS; RECOMBINATION, GENETIC; SELECTION (GENETICS); TIME FACTORS;

EID: 0030924613     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.11.3303     Document Type: Article

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