Alteration of ultraviolet-induced mutagenesis in yeast through molecular modulation of the REV3 and REV7 gene expression

Mutation Research - DNA Repair

Volumn 461, Issue 2, 2000, Pages 133-143

  Rajpal, Deepak K ^a   Wu, Xiaohua ^a   Wang, Zhigang ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Deoxycytidyl transferase; DNA polymerase ; Mutagenesis; UV damage

Indexed keywords

DNA DIRECTED DNA POLYMERASE DELTA; TRANSFERASE;

ARTICLE; DNA DAMAGE; GENE EXPRESSION; MUTAGENESIS; MUTAGENICITY; MUTATION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; ULTRAVIOLET RADIATION; YEAST;

DNA-DIRECTED DNA POLYMERASE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; MUTAGENESIS; NUCLEOTIDYLTRANSFERASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; ULTRAVIOLET RAYS;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0034676229     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(00)00047-1     Document Type: Article

References (35)

1. Lawrence C.W., Krauss B.R., Christensen R.B. New mutations affecting induced mutagenesis in yeast. Mutat. Res. 150:1985;211-216.
2. Lemontt J.F. Pathways of ultraviolet mutability in Saccharomyces cerevisiae. III. Genetic analysis and properties of mutants resistant to ultraviolet-induced forward mutation. Mutat. Res. 43:1977;179-204.
3. Lemontt J.F. Mutants of yeast defective in mutation induction by ultraviolet light. Genetics. 68:1971;21-33.
4. Lawrence C. The RAD6 DNA repair pathway in Saccharomyces cerevisiae: what does it do, and how does it do it? BioEssays. 16:1994;253-258.
5. Lawrence C.W., Hinkle D.C. DNA polymerase ζ and the control of DNA damage induced mutagenesis in eukaryotes. Cancer Surveys. 28:1996;21-31.
6. Lawrence C.W., Das G., Christensen R.B. REV7, a new gene concerned with UV mutagenesis in yeast. Mol. Gen. Genet. 200:1985;80-85.
7. Reynolds P., Weber S., Prakash L. RAD6 gene of Saccharomyces cerevisiae encodes a protein containing a tract of 13 consecutive aspartates. Proc. Natl. Acad. Sci. U. S. A. 82:1985;168-172.
8. Morrison A., Christensen R.B., Alley J., Beck A.K., Bernstine E.G., Lemontt J.F., Lawrence C.W. REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase. J. Bacteriol. 171:1989;5659-5667.
9. Jones J.S., Weber S., Prakash L. The Saccharomyces cerevisiae RAD18 gene encodes a protein that contains potential zinc finger domains for nucleic acid binding and a putative nucleotide binding sequence. Nucleic Acids Res. 16:1988;7119-7131.
10. Chanet R., Magana-Schwencke N., Fabre F. Potential DNA-binding domains in the RAD18 gene product of Saccharomyces cerevisiae. Gene. 74:1988;543-547.
11. E.C. Friedberg, G.C. Walker, W. Siede, DNA Repair and Mutagenesis, American Society of Microbiology Press, Washington, DC, 1995.
12. Nelson J.R., Lawrence C.W., Hinkle D.C. Thymine-thymine dimer bypass by yeast DNA polymerase ζ Science. 272:1996;1646-1649.
13. Lin W., Wu X., Wang Z. A full-length cDNA of hREV3 is predicted to encode DNA polymerase ζ for damage-induced mutagenesis in humans. Mutat. Res. 433:1999;89-98.
14. Kulaeva O.I., Koonin E.V., McDonald J.P., Randall S.K., Rabinovich N., Connaughton J.F., Levine A.S., Woodgate R. Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus. Mutat. Res. 357:1996;245-253.
15. McDonald J.P., Rapic-Otrin V., Epstein J.A., Broughton B.C., Wang X., Lehmann A.R., Wolgemuth D.J., Woodgate R. Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase η Genomics. 60:1999;20-30.
16. Nelson J.R., Lawrence C.W., Hinkle D.C. Deoxycytidyl transferase activity of yeast REV1 protein. Nature. 382:1996;729-731.
17. Lin W., Xin H., Zhang Y., Wu X., Yuan F., Wang Z. The human REV1 gene codes for a DNA template-dependent dCMP transferase. Nucleic Acids Res. 27:1999;4468-4475.
18. Gerlach V.L., Aravind L., Gotway G., Schultz R.A., Koonin E.V., Friedberg E.C. Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily. Proc. Natl. Acad. Sci. U. S. A. 96:1999;11922-11927.
19. Johnson R.E., Prakash S., Prakash L. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη Science. 283:1999;1001-1004.
20. Johnson R.E., Kondratick C.M., Prakash S., Prakash L. hRAD30 mutations in the variant form of xeroderma pigmentosum. Science. 285:1999;263-265.
21. Masutani C., Kusumoto R., Yamada A., Dohmae N., Yokoi M., Yuasa M., Araki M., Iwai S., Takio K., Hanaoka F. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η Nature. 399:1999;700-704.
22. Masutani C., Araki M., Yamada A., Kusumoto R., Nogimori T., Maekawa T., Iwai S., Hanaoka F. Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J. 18:1999;3491-3501.
23. Wagner J., Gruz P., Kim S.R., Yamada M., Matsui K., Fuchs R.P., Nohmi T. The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis. Mol. Cell. 4:1999;281-286.
24. 2C is an error-prone DNA polymerase, Escherichia coli pol V. Proc. Natl. Acad. Sci. U. S. A. 96:1999;8919-8924.
25. Reuven N.B., Arad G., Maor-Shoshani A., Livneh Z. The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication. J. Biol. Chem. 274:1999;31763-31766.
26. Koken M.H.M., Smit E.M.E., Jaspers-Dekker I., Oostra B.A., Hagemeijer A., Bootsma D., Hoeijmakers J.H.J. Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q32. Genomics. 12:1992;447-453.
27. Koken M.H.M., Reynolds P., Jaspers-Dekker I., Prakash L., Prakash S., Bootsma D., Hoeijmakers J.H.J. Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6. Proc. Natl. Acad. Sci. U. S. A. 88:1991;8865-8869.
28. Gibbs P.E., McGregor W.G., Maher V.M., Nisson P., Lawrence C.W. A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase ζ Proc. Natl. Acad. Sci. U. S. A. 95:1998;6876-6880.
29. Gibbs P.E., Wang X.D., Li Z., McManus T.P., McGregor W.G., Lawrence C.W., Maher V.M. The function of the human homolog of saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light. Proc. Natl. Acad. Sci. U. S. A. 97:2000;4186-4191.
30. Gietz R.D., Sugino A. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene. 74:1988;527-534.
31. F.M. Ausubel, R. Brent, R.E. Kinston, D.D. Moore, J.G. Seidman, J.A. Smith, K. Struhl, Current Protocols in Molecular Biology, Greene Publishing Associates and Wiley/Interscience, New York, 1987.
32. Xin H., Lin W., Sumanasekera W., Zhang Y., Wu X., Wang Z. The human RAD18 gene product interacts with HHR6A and HHR6B. Nucleic Acids Res. 28:2000;2847-2854.
33. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
34. Larimer F.W., Perry J.R., Hardigree A.A. The REV1 gene of Saccharomyces cerevisiae: isolation, sequence, and functional analysis. J. Bacteriol. 171:1989;230-237.
35. Murakumo Y., Roth T., Ishii H., Rasio D., Numata S., Croce C.M., Fishel R. A human REV7 homolog that interacts with the polymerase ζ catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2. J. Biol. Chem. 275:2000;4391-4397.