DNA polymerase mu (Pol μ), homologous to TdT, could act as a DNA mutator in eukaryotic cells

EMBO Journal

Volumn 19, Issue 7, 2000, Pages 1731-1742

  Domínguez, Orlando ^a   Ruiz, José F ^a   De Lera, Teresa Laín ^a   García Díaz, Miguel ^a   González, Manuel A ^a   Kirchhoff, Tomas ^a   Martínez A, Carlos ^a   Bernad, Antonio ^a   Blanco, Luis ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Human DNA polymerase; Mutator; Somatic hypermutation; Terminal deoxynucleotidyltransferase

Indexed keywords

DNA; DNA NUCLEOTIDYLEXOTRANSFERASE; DNA POLYMERASE; MAGNESIUM ION; MANGANESE; MESSENGER RNA; MUTAGENIC AGENT; NUCLEOTIDE;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DATA BASE; ENZYME ACTIVITY; ESCHERICHIA COLI; EXPRESSED SEQUENCE TAG; GENE MUTATION; GERMINAL CENTER; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; LYMPHOID TISSUE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY; SOMATIC MUTATION;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELL LINE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 7; DNA; DNA NUCLEOTIDYLEXOTRANSFERASE; DNA PRIMERS; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; GENE EXPRESSION; GENES, IMMUNOGLOBULIN; HUMANS; IN SITU HYBRIDIZATION; LYMPHOID TISSUE; MOLECULAR SEQUENCE DATA; MUTATION; RECOMBINANT PROTEINS; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA; ESCHERICHIA COLI; EUKARYOTA;

EID: 0242634246     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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