메뉴 건너뛰기




Volumn 106, Issue 1, 2000, Pages 15-24

Neuroprotection mediated by changes in the endothelial actin cytoskeleton

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CYTOCHALASIN D; TRANSFERASE;

EID: 0033917736     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI9639     Document Type: Article
Times cited : (254)

References (43)
  • 1
    • 0030711684 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of endothelial cell dysfunction
    • Harrison, D.G. 1997. Cellular and molecular mechanisms of endothelial cell dysfunction. J. Clin. Invest. 100:2153-2157.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2153-2157
    • Harrison, D.G.1
  • 2
    • 0029780767 scopus 로고    scopus 로고
    • Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine
    • Huang, Z., et al. 1996. Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J. Cereb. Blood Flow Metab. 16:981-987.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 981-987
    • Huang, Z.1
  • 3
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott, R.F., and Zawadzki, J.V. 1980. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 4
    • 0025366847 scopus 로고
    • An L-arginine/nitric oxide pathway present in human platelets regulates aggregation
    • Radomski, M.W., Palmer, R.M., and Moncada, S. 1990. An L-arginine/nitric oxide pathway present in human platelets regulates aggregation. Proc. Natl. Acad. Sci. USA 87:5193-5197.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5193-5197
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 5
    • 0032520153 scopus 로고    scopus 로고
    • Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling
    • Rudic, R.D., et al. 1998. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J. Clin. Invest. 101:731-736.
    • (1998) J. Clin. Invest. , vol.101 , pp. 731-736
    • Rudic, R.D.1
  • 6
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes, P., Suzuki, M., and Granger, D.N. 1991. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. USA. 88:4551-4655.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4551-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 7
    • 0029021148 scopus 로고
    • Hypertension in mice lacking the gene for endothelial nitric oxide synthase
    • Huang, P.L., et al. 1995. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature. 377:239-242.
    • (1995) Nature. , vol.377 , pp. 239-242
    • Huang, P.L.1
  • 8
    • 0026761385 scopus 로고
    • Inhibition of nitric oxide synthesis increases focal ischemic infarction in rat
    • Yamamoto, S., Golanov, E.V., Berger, S.B., and Reis, D.J. 1992. Inhibition of nitric oxide synthesis increases focal ischemic infarction in rat. J. Cereb. Blood Flow Metab. 12:717-726.
    • (1992) J. Cereb. Blood Flow Metab. , vol.12 , pp. 717-726
    • Yamamoto, S.1    Golanov, E.V.2    Berger, S.B.3    Reis, D.J.4
  • 9
    • 0032555154 scopus 로고    scopus 로고
    • Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
    • Endres, M., et al. 1998. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc. Natl. Acad. Sci. USA. 95:8880-8885.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8880-8885
    • Endres, M.1
  • 10
    • 0026488606 scopus 로고
    • L-arginine decreases infarct size caused by middle cerebral arterial occlusion in SHR
    • Morikawa, E., Huang, Z., and Moskowitz, M.A. 1992. L-arginine decreases infarct size caused by middle cerebral arterial occlusion in SHR. Am. J. Physiol. 263:H1632-H1635.
    • (1992) Am. J. Physiol. , vol.263
    • Morikawa, E.1    Huang, Z.2    Moskowitz, M.A.3
  • 11
    • 0028180199 scopus 로고
    • L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat
    • Morikawa, E., et al. 1994. L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat. Stroke. 25:429-435.
    • (1994) Stroke. , vol.25 , pp. 429-435
    • Morikawa, E.1
  • 12
    • 0030816797 scopus 로고    scopus 로고
    • A novel anti-inflammatory peptide inhibits endothelial cell cytoskeletal rearrangement, nitric oxide synthase translocation, and paracellular permeability increases
    • Wang, Q., Patton, W.F., Hechtman, H.B., and Shepro, D 1997. A novel anti-inflammatory peptide inhibits endothelial cell cytoskeletal rearrangement, nitric oxide synthase translocation, and paracellular permeability increases. J. Cell Physiol. 172:171-182.
    • (1997) J. Cell Physiol. , vol.172 , pp. 171-182
    • Wang, Q.1    Patton, W.F.2    Hechtman, H.B.3    Shepro, D.4
  • 13
    • 0032409003 scopus 로고    scopus 로고
    • Role of vascular endothelial cell growth factor in Ovarian Hyperstimulation Syndrome
    • Levin, E.R., et al. 1998. Role of vascular endothelial cell growth factor in Ovarian Hyperstimulation Syndrome. J. Clin. Invest. 102:1978-1985.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1978-1985
    • Levin, E.R.1
  • 14
    • 0030871640 scopus 로고    scopus 로고
    • Role of cytoskeleton in shear stress-induced endothelial nitric oxide production
    • Knudsen, H.L., and Frangos, J.A. 1997. Role of cytoskeleton in shear stress-induced endothelial nitric oxide production. Am. J Physiol. 273:11347-11355.
    • (1997) Am. J Physiol. , vol.273 , pp. 11347-11355
    • Knudsen, H.L.1    Frangos, J.A.2
  • 15
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall, A. 1998. Rho GTPases and the actin cytoskeleton. Science. 279:509-514.
    • (1998) Science. , vol.279 , pp. 509-514
    • Hall, A.1
  • 16
    • 0032508533 scopus 로고    scopus 로고
    • Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
    • Laufs, U., and Liao, J.K. 1998. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J. Biol. Chem. 273:24266-24271.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24266-24271
    • Laufs, U.1    Liao, J.K.2
  • 17
    • 0032584177 scopus 로고    scopus 로고
    • Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
    • Laufs, U., LaFata, V., Plutzky, J., and Liao, J.K. 1998. Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 97:1129-1135.
    • (1998) Circulation , vol.97 , pp. 1129-1135
    • Laufs, U.1    Lafata, V.2    Plutzky, J.3    Liao, J.K.4
  • 18
    • 0027945658 scopus 로고
    • Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase
    • Huang, Z., et al. 1994. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science. 265:1883-1885.
    • (1994) Science. , vol.265 , pp. 1883-1885
    • Huang, Z.1
  • 19
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signaling networks
    • Van Aelst, L., and D'Souza-Schorey, C. 1997. Rho GTPases and signaling networks. Genes Dev. 11:2295-2322.
    • (1997) Genes Dev. , vol.11 , pp. 2295-2322
    • Van Aelst, L.1    D'Souza-Schorey, C.2
  • 20
    • 0030462929 scopus 로고    scopus 로고
    • Microtubule disruption induces the formation of actin stress fibers and focal adhesions in cultured cells: Possible involvement of the rho signal cascade
    • Enomoto, T. 1996. Microtubule disruption induces the formation of actin stress fibers and focal adhesions in cultured cells: possible involvement of the rho signal cascade. Cell Struct. Funct. 21:317-326.
    • (1996) Cell Struct. Funct. , vol.21 , pp. 317-326
    • Enomoto, T.1
  • 21
    • 0028914814 scopus 로고
    • Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin
    • Witke, W., et al. 1995. Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. Cell. 81:41-51.
    • (1995) Cell , vol.81 , pp. 41-51
    • Witke, W.1
  • 22
    • 0032473498 scopus 로고    scopus 로고
    • Gelsolin is a downstream effector of rac for fibroblast motility
    • Azuma, T., Witke, W., Stossel, T.P., Hartwig, J.H., and Kwiatkowski, D.J. 1998. Gelsolin is a downstream effector of rac for fibroblast motility. EMBO J. 17:1362-1370.
    • (1998) EMBO J. , vol.17 , pp. 1362-1370
    • Azuma, T.1    Witke, W.2    Stossel, T.P.3    Hartwig, J.H.4    Kwiatkowski, D.J.5
  • 23
    • 0031451344 scopus 로고    scopus 로고
    • Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated downregulation of endothelial nitric oxide synthase
    • Laufs, U., Fata, V.L., and Liao, J K. 1997. Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated downregulation of endothelial nitric oxide synthase. J. Biol. Chem. 272:31725-31729.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31725-31729
    • Laufs, U.1    Fata, V.L.2    Liao, J.K.3
  • 24
    • 0346736491 scopus 로고    scopus 로고
    • Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells
    • Hernandez-Perera, O., et. al. 1998. Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells. J. Clin. Invest. 101:2711-2719.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2711-2719
    • Hernandez-Perera, O.1
  • 25
    • 0027233868 scopus 로고
    • Tumor necrosis factor downregulates an endorhelial nitric oxide synchase mRNA by shortening its half-life
    • Yoshizumi, M., Perrella, M.A., Burnett, J.C., Jr., and Lee, M.E. 1993. Tumor necrosis factor downregulates an endorhelial nitric oxide synchase mRNA by shortening its half-life. Circ. Res. 73:205-209.
    • (1993) Circ. Res. , vol.73 , pp. 205-209
    • Yoshizumi, M.1    Perrella, M.A.2    Burnett J.C., Jr.3    Lee, M.E.4
  • 27
    • 0032537124 scopus 로고    scopus 로고
    • Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions
    • Chicurel, M.E., Singer, R.H., Meyer, C.J., and Ingber, D.E. 1998. Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions. Nature 392:730-733.
    • (1998) Nature. , vol.392 , pp. 730-733
    • Chicurel, M.E.1    Singer, R.H.2    Meyer, C.J.3    Ingber, D.E.4
  • 28
    • 0030912314 scopus 로고    scopus 로고
    • The cytoskeleton in mRNA localization and cell differentiation
    • Nasmyth, K., and Jansen, R.P. 1997. The cytoskeleton in mRNA localization and cell differentiation. Curr. Opin. Cell Biol. 9:396-400.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 396-400
    • Nasmyth, K.1    Jansen, R.P.2
  • 29
    • 0031964360 scopus 로고    scopus 로고
    • Sorting of beta-actin mRNA and protein to neurites and growth cones in culture
    • Bassell, G.J., et al. 1998. Sorting of beta-actin mRNA and protein to neurites and growth cones in culture. J. Neurosci. 18:251-265.
    • (1998) J. Neurosci. , vol.18 , pp. 251-265
    • Bassell, G.J.1
  • 30
    • 0028170820 scopus 로고
    • Small GTP-binding proteins and the regulation of the actin cytoskeleton
    • Hall, A. 1994. Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu. Rev. Cell Biol. 10:31-54.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 31-54
    • Hall, A.1
  • 31
    • 9244257348 scopus 로고    scopus 로고
    • Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
    • Matsui, T., et al. 1996. Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J. 15:2208-2216.
    • (1996) EMBO J. , vol.15 , pp. 2208-2216
    • Matsui, T.1
  • 32
    • 0032498528 scopus 로고    scopus 로고
    • Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
    • Matsui, T., et al. 1998. Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J. Cell Biol. 140:647-657.
    • (1998) J. Cell Biol. , vol.140 , pp. 647-657
    • Matsui, T.1
  • 33
    • 9244220646 scopus 로고    scopus 로고
    • The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase
    • Ishizaki, T., et al. 1996. The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. EMBO J. 15:1885-1893.
    • (1996) EMBO J. , vol.15 , pp. 1885-1893
    • Ishizaki, T.1
  • 34
    • 0029995797 scopus 로고    scopus 로고
    • Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
    • Chrzanowska-Wodnicka, M., and Burridge, K. 1996. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J. Cell Biol 133:1403-1415.
    • (1996) J. Cell Biol. , vol.133 , pp. 1403-1415
    • Chrzanowska-Wodnicka, M.1    Burridge, K.2
  • 35
    • 0030035043 scopus 로고    scopus 로고
    • Identification of a putative target for Rho as the serine-threonine kinase protein kinase N
    • Amano, M., et al. 1996. Identification of a putative target for Rho as the serine-threonine kinase protein kinase N. Science. 271:648-650.
    • (1996) Science. , vol.271 , pp. 648-650
    • Amano, M.1
  • 36
    • 13344285358 scopus 로고    scopus 로고
    • Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho
    • Watanabe, G., et al. 1996. Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho. Science. 271:645-648.
    • (1996) Science. , vol.271 , pp. 645-648
    • Watanabe, G.1
  • 37
    • 0028036684 scopus 로고
    • The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells
    • Chong, L.D., Traynor-Kaplan, A., Bokoch, G.M., and Schwartz, M.A. 1994. The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell. 79:507-513.
    • (1994) Cell. , vol.79 , pp. 507-513
    • Chong, L.D.1    Traynor-Kaplan, A.2    Bokoch, G.M.3    Schwartz, M.A.4
  • 38
    • 0034006811 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment
    • Yamada, M., et al. 2000. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J. Cereb. Blood Flow Metab, 20:709-717.
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 709-717
    • Yamada, M.1
  • 39
    • 0033521078 scopus 로고    scopus 로고
    • Stimulation of bone formation in vitro and in rodents by statins
    • Mundy, G., et al. 1999. Stimulation of bone formation in vitro and in rodents by statins. Science. 286:1946-1949.
    • (1999) Science. , vol.286 , pp. 1946-1949
    • Mundy, G.1
  • 40
    • 0033618378 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)
    • Laufs, U., Marra, D., Node, K., and Liao, J.K. 1999. 3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1). J. Biol. Chem. 274:21926-21931.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21926-21931
    • Laufs, U.1    Marra, D.2    Node, K.3    Liao, J.K.4
  • 41
    • 0344416986 scopus 로고    scopus 로고
    • Monocyte adhesion and spreading on human endothelial cells is dependent on Rho-regulated receptor clustering
    • Wojciak-Stothard, B., Williams, L., and Ridley, A.J. 1999. Monocyte adhesion and spreading on human endothelial cells is dependent on Rho-regulated receptor clustering. J. Cell Biol. 145:1293-1307.
    • (1999) J. Cell Biol. , vol.145 , pp. 1293-1307
    • Wojciak-Stothard, B.1    Williams, L.2    Ridley, A.J.3
  • 42
    • 0032487342 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells. Role of geranylgeranylation and Rho proteins
    • Essig, M., et al. 1998. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells. Role of geranylgeranylation and Rho proteins. Circ. Res. 83:683-690.
    • (1998) Circ. Res. , vol.83 , pp. 683-690
    • Essig, M.1
  • 43
    • 0032489871 scopus 로고    scopus 로고
    • Angiotensin II activates RhoA in cardiac myocytes: A critical role of RhoA in angiotensin II-induced premyofibril formation
    • Aoki, H., Izumo, S., and Sadoshima, J. 1998. Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin II-induced premyofibril formation. Circ. Res. 82:666-676.
    • (1998) Circ. Res. , vol.82 , pp. 666-676
    • Aoki, H.1    Izumo, S.2    Sadoshima, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.