메뉴 건너뛰기




Volumn 277, Issue 3 21-3, 1999, Pages

Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs

Author keywords

Calcium channel blockers; Dysfunctional endothelium; Endothelial nitric oxide synthase; Endothelium dependent responses; Neonatal pulmonary hypertension

Indexed keywords

ACETYLCHOLINE; CALCIUM CHANNEL BLOCKING AGENT; NIFEDIPINE; NITRIC OXIDE SYNTHASE;

EID: 0032887933     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1999.277.3.l449     Document Type: Article
Times cited : (16)

References (22)
  • 1
    • 0023813567 scopus 로고
    • Acute hemodynamic effects of nifedipine in infants with bronchopulmonary dysplasia and pulmonary hypertension
    • Brownlee, J. R., R. H. Beekman, and A. Rosenthal. Acute hemodynamic effects of nifedipine in infants with bronchopulmonary dysplasia and pulmonary hypertension. Pediatr. Res. 24: 186-190, 1988.
    • (1988) Pediatr. Res. , vol.24 , pp. 186-190
    • Brownlee, J.R.1    Beekman, R.H.2    Rosenthal, A.3
  • 2
    • 0029072762 scopus 로고
    • Flow-mediated endothelial mechanotransduction
    • Davies, P. F. Flow-mediated endothelial mechanotransduction. Physiol. Rev. 75: 519-560, 1995.
    • (1995) Physiol. Rev. , vol.75 , pp. 519-560
    • Davies, P.F.1
  • 3
    • 0031593125 scopus 로고    scopus 로고
    • Effects of amolodipine on gene expression and extracellular matrix formation in human vascular smooth muscle cells and fibroblasts: Implications for vascular protection
    • Eickelberg, O., M. Roth, and L.-H. Block. Effects of amolodipine on gene expression and extracellular matrix formation in human vascular smooth muscle cells and fibroblasts: implications for vascular protection. Int. J. Cardiol. 62, Suppl. 2: S31-S37, 1997.
    • (1997) Int. J. Cardiol. , vol.62 , Issue.SUPPL. 2
    • Eickelberg, O.1    Roth, M.2    Block, L.-H.3
  • 4
    • 0028603561 scopus 로고
    • Effect of chronic hypoxia on pulmonary vascular pressures in isolated lungs of newborn pigs
    • Fike, C. D., and M. R. Kaplowitz. Effect of chronic hypoxia on pulmonary vascular pressures in isolated lungs of newborn pigs. J. Appl. Physiol. 77: 2853-2862, 1994.
    • (1994) J. Appl. Physiol. , vol.77 , pp. 2853-2862
    • Fike, C.D.1    Kaplowitz, M.R.2
  • 5
    • 0029803861 scopus 로고    scopus 로고
    • Chronic hypoxia alters nitric oxide-dependent pulmonary vascular responses in lungs of newborn pigs
    • Fike, C. D., and M. R. Kaplowitz. Chronic hypoxia alters nitric oxide-dependent pulmonary vascular responses in lungs of newborn pigs. J. Appl. Physiol. 81: 2078-2087, 1996.
    • (1996) J. Appl. Physiol. , vol.81 , pp. 2078-2087
    • Fike, C.D.1    Kaplowitz, M.R.2
  • 6
    • 0031969359 scopus 로고    scopus 로고
    • Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs
    • Lung Cell. Mol. Physiol. 18
    • Fike, C. D., M. R. Kaplowitz, C. J. Thomas, and L. D. Nelin. Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs. Am. J. Physiol. 274 (Lung Cell. Mol. Physiol. 18): L517-L526, 1998.
    • (1998) Am. J. Physiol. , vol.274
    • Fike, C.D.1    Kaplowitz, M.R.2    Thomas, C.J.3    Nelin, L.D.4
  • 8
    • 85047677343 scopus 로고
    • Effect of hypoxia on adaptation of the pulmonary circulation to extra-uterine life in the pig
    • Haworth, S. G., and A. A. Hislop. Effect of hypoxia on adaptation of the pulmonary circulation to extra-uterine life in the pig. Cardiovasc. Res. 16: 293-303, 1982.
    • (1982) Cardiovasc. Res. , vol.16 , pp. 293-303
    • Haworth, S.G.1    Hislop, A.A.2
  • 9
    • 0017233694 scopus 로고
    • Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs
    • McMurtry, I. F., A. B. Davidson, J. T. Reeves, and R. F. Grover. Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs. Circ. Res. 38: 99-104, 1976.
    • (1976) Circ. Res. , vol.38 , pp. 99-104
    • McMurtry, I.F.1    Davidson, A.B.2    Reeves, J.T.3    Grover, R.F.4
  • 10
    • 0027938194 scopus 로고
    • Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms
    • Heart Circ. Physiol. 36
    • McQuillan, G., K. Leung, P.A. Marsden, S. K. Kostyk, and S. Kourembanas. Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H1921-H1927, 1994.
    • (1994) Am. J. Physiol. , vol.267
    • McQuillan, G.1    Leung, K.2    Marsden, P.A.3    Kostyk, S.K.4    Kourembanas, S.5
  • 11
  • 12
    • 0031027730 scopus 로고    scopus 로고
    • Novel uses and potential for calcium antagonists in revascularization
    • Nikol, S., T. Y. Huehns, and B. Hofling. Novel uses and potential for calcium antagonists in revascularization. Eur. Heart J. 18, Suppl. A: A105-A109, 1997.
    • (1997) Eur. Heart J. , vol.18 , Issue.SUPPL. A
    • Nikol, S.1    Huehns, T.Y.2    Hofling, B.3
  • 13
    • 0025361852 scopus 로고
    • Endothelial cell thromboxane production and its inhibition by a calcium-channel blocker
    • Ramadan, F. M., G. R. Upchurch, B. A. Keagy, and G. Johnson. Endothelial cell thromboxane production and its inhibition by a calcium-channel blocker. Ann. Thorac. Surg. 49: 916-919, 1990.
    • (1990) Ann. Thorac. Surg. , vol.49 , pp. 916-919
    • Ramadan, F.M.1    Upchurch, G.R.2    Keagy, B.A.3    Johnson, G.4
  • 14
    • 0027992492 scopus 로고
    • Calcium regulation of immediate-early response genes
    • Roche, E., and M. Prentki. Calcium regulation of immediate-early response genes. Cell Calcium 16: 331-338, 1994.
    • (1994) Cell Calcium , vol.16 , pp. 331-338
    • Roche, E.1    Prentki, M.2
  • 15
    • 0029664633 scopus 로고    scopus 로고
    • Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix
    • Roth, M., O. Eickelberg, E. Kohler, P. Erne, and L. Block. Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix. Proc. Natl. Acad. Sci. USA 93: 5478-5482, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5478-5482
    • Roth, M.1    Eickelberg, O.2    Kohler, E.3    Erne, P.4    Block, L.5
  • 16
    • 0030954154 scopus 로고    scopus 로고
    • Pulmonary endothelial NO synthase gene expression is decreased in fetal lambs with pulmonary hypertension
    • Lung Cell. Mol. Physiol. 16
    • Shaul, P. W., I. S. Yuhanna, Z. German, Z. Chen, R. H. Steinhorn, and F. C. Morin III. Pulmonary endothelial NO synthase gene expression is decreased in fetal lambs with pulmonary hypertension. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L1005-L1012, 1997.
    • (1997) Am. J. Physiol. , vol.272
    • Shaul, P.W.1    Yuhanna, I.S.2    German, Z.3    Chen, Z.4    Steinhorn, R.H.5    Morin F.C. III6
  • 17
    • 0021256431 scopus 로고
    • Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists
    • Stanbrook, H. S., K. G. Morris, and I. F. McMurtry. Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists. Am. Rev. Respir. Dis. 130: 81-85, 1984.
    • (1984) Am. Rev. Respir. Dis. , vol.130 , pp. 81-85
    • Stanbrook, H.S.1    Morris, K.G.2    McMurtry, I.F.3
  • 19
    • 0030998369 scopus 로고    scopus 로고
    • Chronic hypoxia inhibits postnatal maturation of porcine intrapulmonary artery relaxation
    • Heart Circ. Physiol. 41
    • Tulloh, R. M. R., A. A. Hislop, P. J. Boels, J. Deutsch, and S. G. Haworth. Chronic hypoxia inhibits postnatal maturation of porcine intrapulmonary artery relaxation. Am. J. Physiol. 272 (Heart Circ. Physiol. 41): H2436-H2445, 1997.
    • (1997) Am. J. Physiol. , vol.272
    • Tulloh, R.M.R.1    Hislop, A.A.2    Boels, P.J.3    Deutsch, J.4    Haworth, S.G.5
  • 20
    • 0028304046 scopus 로고
    • Chronic hypoxic pulmonary hypertension: Cell biology to pathophysiology
    • Vender, R. L. Chronic hypoxic pulmonary hypertension: cell biology to pathophysiology. Chest 106: 236-243, 1994.
    • (1994) Chest , vol.106 , pp. 236-243
    • Vender, R.L.1
  • 21
    • 0030979142 scopus 로고    scopus 로고
    • Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus
    • Lung Cell. Mol. Physiol. 16
    • Villamor, E., T. D. Le Cras, M. P. Horan, A. C. Halbower, R. M. Tuder, and S. H. Abman. Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L1013-L1020, 1997.
    • (1997) Am. J. Physiol. , vol.272
    • Villamor, E.1    Cras, T.D.L.2    Horan, M.P.3    Halbower, A.C.4    Tuder, R.M.5    Abman, S.H.6
  • 22
    • 0028844334 scopus 로고
    • Cellular and molecular mechanisms in the pathogenesis of severe pulmonary hypertension
    • Voelkel, N. F., and R. M. Tuder. Cellular and molecular mechanisms in the pathogenesis of severe pulmonary hypertension. Eur. Respir. J. 8: 2129-2138, 1995.
    • (1995) Eur. Respir. J. , vol.8 , pp. 2129-2138
    • Voelkel, N.F.1    Tuder, R.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.