Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 15, 1998, Pages 8880-8885

  Endres, Matthias ^a   Laufs, Ulrich ^b   Huang, Zhihong ^a   Nakamura, Tadashi ^a   Huang, Paul ^a   Moskowitz, Michael A ^a   Liao, James K ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cerebral blood flow; Cerebral ischemia

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; NITRIC OXIDE SYNTHASE; SIMVASTATIN;

ANIMAL EXPERIMENT; BRAIN INJURY; BRAIN ISCHEMIA; CHOLESTEROL BLOOD LEVEL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; STROKE;

ANIMALIA;

EID: 0032555154     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.15.8880     Document Type: Article

References (44)

1. Division of Chronic Disease Control and Community (1994) Cardiovascular Disease Surveillance: Stroke, 1980-1989 (Atlanta, Centers for Disease Control and Prevention).
2. Patrono, C. (1994) N. Engl. J. Med. 330, 1287-1294.
3. Goldstein, J. L. & Brown, M. S. (1990) Nature (London) 343, 425-430.
4. Massy, Z. A., Keane, W. F, & Kasiske, B. L (1996) Lancet 347, 102-103.
5. Cholesterol and Recurrent Events Trial Investigators (1996) N. Engl. J. Med. 335, 1001-1009.
6. Scandinavian Simvastatin Survival Study Group (1994) Lancet 344, 1383-1389.
7. Shepherd, J., Cobbe, S. M., Ford, I., Isles, C. G., Lorimer, A. R., MacFarlane, P. W., McKillop, J. H. & Packard, C. J. (1995) N. Engl. J. Med. 333, 1301-1307.
8. Blauw, G. J., Lagaay, A. M., Smelt, A. H. & Westendorp, R. G. (1997) Stroke 28, 946-950.
9. Gerson, R. J., MacDonald, J., Alberts, A. W., Kornbrust, J., Majka, J. A., Stubbs, J. & Bokelman, D. L. (1989) Am. J. Med. 87, 28-38.
10. Hebert, P. R., Gaziano, J. M., Chan, K. S. & Hennekens, C. H. (1997) J. Am. Med. Assoc. 27, 313-321.
11. Libby, P. (1995) Circulation 91, 2844-2850.
12. Packard, C. J. (1998) Circulation 97, 1440-1445.
13. Buchwald, H., Varco, R. L., Matts, J. P., Long, J. M., Fitch, L. L., Campbell, G. S., Pearce, M. B., Yellin, A. E., Edmiston, W. A. & Smik, R. D., Jr. (1990) N. Engl. J. Med. 323, 946-955.
14. Anderson, T. J., Meredith, I. T., Yeung, A. C., Frei, B., Selwyn, A. P. & Ganz, P. (1995) N. Engl. J. Med. 332, 488-493.
15. O'Driscoll, G., Green, D. & Taylor, R. R. (1997) Circulation 95, 1126-1131.
16. Williams, J. K., Sukhova, G. K., Herrington, D. M. & Libby, P. (1998) J. Am. Coll. Cardiol. 31, 684-691.
17. Treasure, C. B., Klein, J. L., Weintraub, W. S., Talley, J. D., Stillabower, M. E., Kosinski, A. S., Zhang, J., Boccuzzi, S. J., Cedarholm, J. C. & Alexander R. W. (1995) N. Engl. J. Med. 334, 481-487.
18. Liao, J. K., Zulueta, J. J., Feng-Sheng, Y., Peng, H., Cote, C. G. & Hassoun, P. M. (1995) J. Clin. Invest. 96, 2661-2666.
19. Laufs, U., La Fata, V. & Liao, J. K. (1997) J. Biol. Chem. 272, 31725-31729.
20. Laufs, U., La Fata, V., Plutzky, J. & Liao, J. K. (1998) Circulation 97, 1129-1135.
21. Palmer, R. M. J., Ferrige, A. G. & Moncada, S. (1987) Nature (London) 327, 524-526.
22. Radomski, M. W., Palmer, R. M. & Moncada, S. (1990) Proc. Natl. Acad. Sci. USA 87, 5193-5197.
23. Huang, P. L., Huang, Z., Mashimo, H., Bloch, K. D., Moskowitz, M. A., Bevan, J. A. & Fishman, M. C. (1995) Nature (London) 377, 239-242.
24. Furchgott, R. F. & Zawadzki, J. V. (1980) Nature (London) 288, 373-376.
25. Ignarro, L. J. (1990) Annu. Rev. Pharmacol. Toxicol. 30, 535-560.
26. Huang, Z., Huang, P. L., Ma, J., Meng, W., Ayata, C., Fishman, M. C. & Moskowitz, M. A. (1996) J. Cereb. Blood Flow Metab. 16, 981-987.
27. Huang, Z., Huang, P. L., Panahian, N., Dalkara, T., Fishman, M. C. & Moskowitz, M. A. (1994) Science 265, 1883-1885.
28. Dalkara, T., Morikawa, E., Panahian, N. & Moskowitz, M. A. (1994) Am. J. Physiol. 267, H678-H683.
29. Zhang, F. & Iadecola, C. (1994) J. Cereb. Blood Flow Metab. 14, 574-580.
30. Morikawa, E., Huang, Z. & Moskowitz, M. A. (1992) Am. J. Physiol. 263, H1632-H1635.
31. Pahlman, S., Odelstad, L., Larson, E., Grotte, G. & Nilsson, K. (1981) Int. J. Cancer 28, 583-589.
32. Brandt, R., Leger, J. & Lee, G. (1995) J. Cell. Biol. 131, 1327-40.
33. Endres, M., Wang, Z.-Q., Namura, S., Waeher, C. & Moskowitz, M. A. (1997) J. Cereb. Blood Flow Metab. 17, 1143-1151.
34. Fujii, M., Hara, H., Meng, W., Vonsattel, J. P., Huang, Z. & Moskowitz, M. A. (1997) Stroke (Dallas) 28, 1805-1811.
35. Hara, H., Ayata, C, Huang, P. L., Waeber, C, Ayata, G., Fujii, M. & Moskowitz, M. A. (1997) J. Cereb. Blood Flow Metab. 17, 515-526.
36. Nadaud, S., Philippe, M., Arnal, J.-F., Michel, J.-B. & Soubrier, F. (1996) Circ. Res. 79, 857-863.
37. Haddad, E. K., Duclos, A. J., Lapp, W. S. & Baines, M. G. (1997) J. Immunol. 158, 4886-4892.
38. Van Vliet, A. K., Negre-Aminou, P., van Thiel, G. C, Bolhuis, P. A. & Cohen, L. H. (1996) Biochem. Pharmacol. 52, 1387-1392.
39. Hara, H., Huang, P. L., Panahian, N, Fishman, M. C. & Moskowitz (1996) J. Cereb. Blood Flow Metab. 16, 605-611.
40. Ma, J., Endres, M. & Moskowitz, M. A. (1998) Br. J. Pharmacol., in press.
41. Hara H., Friedlander R. M., Gagliardini, V., Ayata, C., Fink, K. B., Huang, Z., Shimizu-Sasamata, M., Yuan, J. & Moskowitz, M. A. (1997) Proc. Natl. Acad. Sci. USA 94, 2007-2012.
42. Sila, C. A. (1998) Neurol. Clin. 16, 9-20.
43. Giaid, A. & Saleh, D. (1995) N. Engl. J. Med 333, 214-221.
44. Katz, S. D. (1997) Curr. Opin. Cardiol. 12, 259-264.