Effects of amlodipine on nitric oxide synthase mRNA expression and coronary microcirculation in prolonged nitric oxide blockade-induced hypertensive rats

Journal of Cardiovascular Pharmacology

Volumn 34, Issue 2, 1999, Pages 173-181

  Kobayashi, Naohiko ^a   Yanaka, Hatsuko ^a   Tojo, Akihiro ^b   Kobayashi, Kiminari ^a   Matsuoka, Hiroaki ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Calcium antagonist; Coronary circulation; Hypertension; Microcirculation; Nitric Oxide

Indexed keywords

AMLODIPINE; CALCIUM ANTAGONIST; COLLAGEN TYPE 1; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE THERAPY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DISEASE SIMULATION; ENZYME ACTIVITY; ENZYME INDUCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE WALL; HEART VENTRICLE REMODELING; HISTOLOGY; HYPERTENSION; MALE; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

AMLODIPINE; ANIMALS; CALCIUM CHANNEL BLOCKERS; CORONARY CIRCULATION; HEMODYNAMIC PROCESSES; HYPERTENSION; MALE; MICROCIRCULATION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0032787942     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199908000-00001     Document Type: Article

References (41)

1. Grossman W, Jones D, McLaurin LP. Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest 1975;56:56-64.
2. Chilian WM, Marcus ML. Coronary vascular adaptations to myocardial hypertrophy. Annu Rev Physiol 1987;49:477-87.
3. Bache RJ. Effects of hypertrophy on the coronary circulation. Prog Cardiovasc Dis 1988;30:403-40.
4. Cuspidi C, Lonati L, Sampieri L, et al. Left ventricular concentric remodelling and carotid structural changes in essential hypertension. J Hypertens 1996;14:1441-6.
5. Konishi M, Su C. Role of endothelium in dilator responses of spontaneously hypertensive rat arteries. Hypertension 1983;5: 881-6.
6. Panza JA, Quyyumi AA, Brush JE Jr, Epstein SE. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990;323:22-7.
7. Luscher TF, Vanhoutte PM, Raij L. Antihypertensive treatment normalizes decreased endothelium-dependent relaxation in rats with salt-induced hypertension. Hypertension 1987;9(suppl III): III-193-7.
8. Panza JA, Quyyumi AA, Callahan TS, Epstein SE. Effect of antihypertensive treatment on endothelium-dependent vascular relaxation in patients with essential hypertension. J Am Coll Cordiol 1993;21:1145-51.
9. 2α-precontracted porcine isolated arteries after pretreatment with methylene blue. Basic Res Cardiol 1990;85: 461-6.
10. Günther J, Dhein S, Rösen R, Klaus W, Fricke U. Nitric oxide (EDRF) enhances the vasorelaxing effect of nitrendipine in various isolated arteries. Basic Res Cardiol 1992;87:452-60.
11. Leenen FHH, Fourney A. Comparison of the effects of amlodipine and diltiazem on 24-hour blood pressure, plasma catecholamines, and left ventricular mass. Am J Cardiol 1996;78:203-7.
12. Julius S. Amlodipine in hypertension: an overview of the clinical dossier. J Cardiovasc Pharmacol 1988;12(suppl 7):S27-33.
13. Gross GJ, Farber NE, Pieper GM. Effects of amlodipine on myocardial ischemia-reperfusion injury in dogs. Am J Cardiol 1989; 64:940-2.
14. Kobayashi N, Kobayashi K, Kouno K, Yagi S, Matsuoka H. Effect of benidipine on microvascular remodeling and coronary flow reserve in two-kidney one clip Goldblatt hypertension. J Hypertens 1997;15:1285-94.
15. Kobayashi K, Tarazi RC. Effect of nitrendipine on coronary flow and ventricular hypertrophy in hypertension. Hypertension 1983; 5(suppl II):II-45-51.
16. Kobayashi K, Tarazi RC. The chronic effect of nitrendipine on heart and regional blood flow in renovascular hypertensive rats. Jpn Circ J 1987;51:1027-34.
17. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-9.
18. Hattori Y, Gross SS. GTP cyclohydrolase I mRNA is induced by LPS in vascular smooth muscle: characterization, sequence and relationship to nitric oxide synthase. Biochem Biophys Res Commun 1993;195:435-41.
19. Seki T, Naruse M, Naruse K, et al. Gene expression of endothelial type isoform of nitric oxide synthase in various tissues of stroke-prone spontaneously hypertensive rats. Hypertens Res 1997;20: 43-9.
20. Nicoletti A, Heudes D, Hinglais N, et al. Left ventricular fibrosis in renovascular hypertensive rats: effect of losartan and spironolactone. Hypertension 1995;26:101-11.
21. Terada Y, Tomita K, Nonoguchi H, Marumo F. Polymerase chain reaction localization of constitutive nitric oxide synthase and soluble guanylate cyclase messenger RNAs in microdissected rat nephron segments. J Clin Invest 1992;90:659-65.
22. Hattori Y, Akimoto K, Murakami Y, Kasai K. Pyrrolidine dithiocarbamate inhibits cytokine-induced VCAM-1 gene expression in rat cardiac myocytes. Mol Cell Biochem 1997;177:177-81.
23. Numaguchi K, Egashira K, Takemoto M, et al. Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats. Hypertension 1995;26(pt 1):957-62.
24. Wicker P, Tarazi RC. Importance of injection site for coronary blood flow determinations by microspheres in rats. Am J Physiol 1982;242:H94-7.
25. Kobayashi K, Tarazi RC, Lovenberg W, Rakusan K. Coronary blood flow in genetic cardiac hypertrophy. Am J Cardiol 1984;53: 1360-4.
26. Wicker P, Tarazi RC, Kobayashi K. Coronary blood flow during the development and regression of left ventricular hypertrophy in renovascular hypertensive rats. Am J Cardiol 1983;51:1744-9.
27. Kobayashi N, Kobayashi K, Kouno K, Horinaka S, Yagi S. Effects of intra-atrial injection of colored microspheres on systemic hemodynamics and regional blood flow in rats. Am J Physiol 1994; 266:H1910-7.
28. Kobayashi N, Kobayashi K, Kouno K, et al. Effects of microsphere suspension agents on systemic hemodynamics in rats: comparison of nonradioactive colored and radioactive microspheres. Jpn Mean J 1994;35:467-75.
29. Hale SL, Alker KJ, Kloner RA. Evaluation of nonradioactive colored microspheres for measurement of regional myocardial blood flow in dogs. Circulation 1988;78:428-34.
30. Kowallik P, Schulz R, Guth BD, et al. Measurement of regional myocardial blood flow with multiple colored microspheres. Circulation 1991;83:974-82.
31. Tojo A, Kobayashi N, Kimura K, et al. Effects of antihypertensive drugs on nitric oxide synthase activity in rat kidney. Kidney Int 1996;49(suppl 55):S-138-40.
32. Takanohashi A, Tojo A, Kobayashi N, Yagi S, Matsuoka H. Effect of trichlormethiazide and captopril on nitric oxide synthase activity in the kidney of deoxycorticosterone acetate-salt hypertensive rats. Jpn Heart J 1996;37:251-9.
33. Kobayashi N, Kobayashi K, Hara K, et al. Benidipine stimulates nitric oxide synthase and improves coronary circulation in hypertensive rats. Am J Hypertens 1999;12:483-91.
34. Dohi Y, Kojima M, Sato K. Benidipine improves endothelial function in renal resistance arteries of hypertensive rats. Hypertension 1996;28:58-63.
35. Dohi Y, Criscione L, Pfeiffer K, Lüscher TF. Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries. J Cardiovasc Pharmacol 1994;24:372-9.
36. Zhang X, Hintze T. Amlodipine releases nitric oxide from canine coronary microvessels: an unexpected mechanism of action of a calcium channel-blocking agent. Circulation 1998;97:576-80.
37. Vilaine JP, Biondi ML, Villeneuve N, Feletou M, Peglion JL, Vanhoutte PM. The calcium channel antagonist S 11568 causes endothelium-dependent relaxation in canine arteries. Eur J Pharmacol 1991;197:41-8.
38. Strauer BE, Vogt M, Motz W. ACE-inhibitors and coronary microcirculation. Basic Res Cardiol 1993;88(suppl 1):97-106.
39. Bouma P, Ferdinandy P, Sipkema P, Allaart C, Westerhof N. Nitric oxide is an important determinant of coronary flow in the isolated blood perfused rat heart. Basic Res Cardiol 1992;87:570-84.
40. Lüscher TF, Raij L, Vanhoutte PM. Endothelium-dependent vascular responses in normotensive and hypertensive Dahl rats. Hypertension 1987;9:157-63.
41. Gibbons GH, Dzau VJ. The emerging concept of vascular remodeling. N Engl J Med 1994;330:1431-8.