TCV-116 stimulates eNOS and caveolin-1 expression and improves coronary microvascular remodeling in normotensive and angiotensin II-induced hypertensive rats

Atherosclerosis

Volumn 158, Issue 2, 2001, Pages 359-368

  Kobayashi, Naohiko ^a,b   Mori, Yousuke ^a   Nakano, Shigefumi ^a   Tsubokou, Yusuke ^a   Kobayashi, Tsutomu ^a   Shirataki, Hiromichi ^a   Matsuoka, Hiroaki ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

^b Institute for Medical Science Dokkyo University School of Medicine Mibu ^*  (Japan)

Author keywords

Angiotensin II type 1 receptor antagonist; Caveolin 1; Gene expression; Hypertension; Nitric oxide synthase

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN ANTAGONIST; CANDESARTAN HEXETIL; CAVEOLIN 1; COLLAGEN TYPE 1; MESSENGER RNA; NITRIC OXIDE SYNTHASE; REGULATOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DIAMETER; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; CORONARY BLOOD VESSEL; ENDOTHELIUM; ENZYME ACTIVITY; HEART LEFT VENTRICLE; HEART MUSCLE FIBROSIS; HEART VENTRICLE REMODELING; HYPERTENSION; MALE; MICROVASCULARIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANGIOTENSIN II; ANIMALS; ARTERIOLES; BENZIMIDAZOLES; BIPHENYL COMPOUNDS; CAPILLARIES; CAVEOLIN 1; CAVEOLINS; COLLAGEN TYPE I; CORONARY VESSELS; GENE EXPRESSION; HYPERTENSION; MALE; MYOCARDIUM; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; NITRITES; RATS; RATS, INBRED WKY; RECEPTORS, ANGIOTENSIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRAZOLES;

EID: 0034813223     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(01)00458-0     Document Type: Article

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