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Volumn 28, Issue 5, 1996, Pages 743-753

Upregulation of nitric oxide synthase correlates temporally with onset of pulmonary vascular remodeling in the hypoxic rat

Author keywords

anoxia; cGMP; endothelium, vascular; guanylate cyclase; hypertension, pulmonary; muscle, smooth, vascular; nitric oxide; nitric oxide synthase

Indexed keywords

DNA; GUANYLATE CYCLASE; MESSENGER RNA; NITRIC OXIDE SYNTHASE; PROTEIN;

EID: 0029957529     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.28.5.743     Document Type: Article
Times cited : (126)

References (47)
  • 1
    • 85047679433 scopus 로고
    • Hemodynamic and pathological study of the effect of chronic hypoxia and subsequent recovery of the heart and pulmonary vasculature of the rat
    • Abraham AS, Kay JM, Cole RB, Pincock AC. Hemodynamic and pathological study of the effect of chronic hypoxia and subsequent recovery of the heart and pulmonary vasculature of the rat. Cardiovasc Res. 1971;5:95-102.
    • (1971) Cardiovasc Res , vol.5 , pp. 95-102
    • Abraham, A.S.1    Kay, J.M.2    Cole, R.B.3    Pincock, A.C.4
  • 2
    • 0001842458 scopus 로고
    • Formation of the pulmonary vasculature
    • Hodson WA, ed. New York, NY: Marcel Dekker
    • Hislop A, Reid LM. Formation of the pulmonary vasculature. In: Hodson WA, ed. Development of the Lung. New York, NY: Marcel Dekker; 1977:37-86.
    • (1977) Development of the Lung , pp. 37-86
    • Hislop, A.1    Reid, L.M.2
  • 3
    • 0018487516 scopus 로고
    • Rat pulmonary circulation after chronic hypoxia: Hemodynamic and structural features
    • Rabinovitch M, Gamble W, Nadas AS, Miettinen OS, Reid L. Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural features. Am J Physiol. 1979;236:H818-H827.
    • (1979) Am J Physiol , vol.236
    • Rabinovitch, M.1    Gamble, W.2    Nadas, A.S.3    Miettinen, O.S.4    Reid, L.5
  • 4
    • 0024426035 scopus 로고
    • Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor
    • Archer SL, Tolins JP, Raij L, Weir EK. Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor. Biochem Biophys Res Commun. 1989; 164:1198-1205.
    • (1989) Biochem Biophys Res Commun , vol.164 , pp. 1198-1205
    • Archer, S.L.1    Tolins, J.P.2    Raij, L.3    Weir, E.K.4
  • 5
    • 0022569705 scopus 로고
    • Mechanisms of hypoxic pulmonary vasoconstriction
    • Voelkel NF. Mechanisms of hypoxic pulmonary vasoconstriction. Am Rev Respir Dis. 1986;133:1186-1195.
    • (1986) Am Rev Respir Dis , vol.133 , pp. 1186-1195
    • Voelkel, N.F.1
  • 6
    • 0027295116 scopus 로고
    • Disorders of endothelium-dependent relaxation in pulmonary disease
    • Dinh-Xuan AT. Disorders of endothelium-dependent relaxation in pulmonary disease. Circulation. 1993;87(suppl V):V-81-V-87.
    • (1993) Circulation , vol.87 , Issue.5 SUPPL.
    • Dinh-Xuan, A.T.1
  • 7
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology and pharmacology
    • Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev. 1991;43:109-142.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 8
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature. 1987;327:524-526.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 9
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980;288:373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 10
    • 0025763933 scopus 로고
    • W-nitro-L-arginine attenuates endothelium-dependent pulmonary vasodilation in lambs
    • W-nitro-L-arginine attenuates endothelium-dependent pulmonary vasodilation in lambs. Am J Physiol. 1991;260:H299-H306.
    • (1991) Am J Physiol , vol.260
    • Fineman, J.R.1    Heymann, M.A.2    Soifer, S.J.3
  • 11
    • 0026654809 scopus 로고
    • EDRF inhibition augments pulmonary hypertension in intact newborn lambs
    • Fineman JR, Chang R, Soifer SJ. EDRF inhibition augments pulmonary hypertension in intact newborn lambs. Am J Physiol. 1992; 262:H1365-H1371.
    • (1992) Am J Physiol , vol.262
    • Fineman, J.R.1    Chang, R.2    Soifer, S.J.3
  • 13
    • 0025963441 scopus 로고
    • Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia
    • Adnot S, Raffestin B, Eddahibi S, Braquet P, Chabrier PE. Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia. J Clin Invest. 1991;87:155-162.
    • (1991) J Clin Invest , vol.87 , pp. 155-162
    • Adnot, S.1    Raffestin, B.2    Eddahibi, S.3    Braquet, P.4    Chabrier, P.E.5
  • 17
    • 0026525292 scopus 로고
    • Relationship between chronic hypoxia and in vitro pulmonary relaxation mediated by endothelium-derived relaxing factors in human chronic obstructive lung disease
    • Dinh-Xuan AT, Higenbottam TW, Wallwork J. Relationship between chronic hypoxia and in vitro pulmonary relaxation mediated by endothelium-derived relaxing factors in human chronic obstructive lung disease. Angiology. 1992;43:350-356.
    • (1992) Angiology , vol.43 , pp. 350-356
    • Dinh-Xuan, A.T.1    Higenbottam, T.W.2    Wallwork, J.3
  • 18
    • 10344261357 scopus 로고
    • Mechanisms of pulmonary hypertension: An overview
    • Will JA, Dawson CA, Weir EK, Buckner CK, eds. Orlando, Fla: Academic Press
    • Barer GR, Emery CJ, Bee D, Wach RA. Mechanisms of pulmonary hypertension: an overview. In: Will JA, Dawson CA, Weir EK, Buckner CK, eds. The Pulmonary Circulation in Health and Disease. Orlando, Fla: Academic Press; 1987:409-422.
    • (1987) The Pulmonary Circulation in Health and Disease , pp. 409-422
    • Barer, G.R.1    Emery, C.J.2    Bee, D.3    Wach, R.A.4
  • 19
    • 0027451371 scopus 로고
    • Chronic EDRF inhibition and hypoxic effects on pulmonary circulation and systemic blood pressure
    • Hampl V, Archer SL, Nelson DP, Weir K. Chronic EDRF inhibition and hypoxic effects on pulmonary circulation and systemic blood pressure. J Appl Physiol. 1993;75:1748-1757.
    • (1993) J Appl Physiol , vol.75 , pp. 1748-1757
    • Hampl, V.1    Archer, S.L.2    Nelson, D.P.3    Weir, K.4
  • 20
    • 0029041124 scopus 로고
    • Hypoxia potentiates nitric oxide synthase and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells
    • Hampl V, Cornfield DN, Cowan NJ, Archer SL. Hypoxia potentiates nitric oxide synthase and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells. Eur Respir J. 1995;8: 515-522.
    • (1995) Eur Respir J , vol.8 , pp. 515-522
    • Hampl, V.1    Cornfield, D.N.2    Cowan, N.J.3    Archer, S.L.4
  • 21
    • 0027975558 scopus 로고
    • Effects of endogenous nitric oxide on pulmonary vascular tone in intact dogs
    • Leeman M, de Beyl VZ, Delcroix M, Naeije R. Effects of endogenous nitric oxide on pulmonary vascular tone in intact dogs. Am J Physiol. 1994;266:H2343-H2347.
    • (1994) Am J Physiol , vol.266
    • Leeman, M.1    De Beyl, V.Z.2    Delcroix, M.3    Naeije, R.4
  • 22
    • 0027370627 scopus 로고
    • Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms
    • Shaul PW, Wells LB, Horning KM. Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms. J Cardiovasc Pharmacol. 1993;22: 819-827.
    • (1993) J Cardiovasc Pharmacol , vol.22 , pp. 819-827
    • Shaul, P.W.1    Wells, L.B.2    Horning, K.M.3
  • 25
    • 0030041523 scopus 로고    scopus 로고
    • Chronic inhaled nitric oxide: Effects on pulmonary endothelial function and pathology in hypoxic and normoxic rats
    • Roos CM, Frank DU, Xue C, Johns RA, Rich GF. Chronic inhaled nitric oxide: effects on pulmonary endothelial function and pathology in hypoxic and normoxic rats. J Appl Physiol. 1996;80:252-260.
    • (1996) J Appl Physiol , vol.80 , pp. 252-260
    • Roos, C.M.1    Frank, D.U.2    Xue, C.3    Johns, R.A.4    Rich, G.F.5
  • 26
    • 4243579982 scopus 로고
    • Endothelial NO synthase mRNA and protein, and inducible NO synthase mRNA are upregulated in the rat lung following chronic hypoxia
    • Le Cras TD, Xue C, Dailey GC, Johns RA. Endothelial NO synthase mRNA and protein, and inducible NO synthase mRNA are upregulated in the rat lung following chronic hypoxia. Am J Respir Crit Care Med. 1995;151:A729.
    • (1995) Am J Respir Crit Care Med , vol.151
    • Le Cras, T.D.1    Xue, C.2    Dailey, G.C.3    Johns, R.A.4
  • 27
    • 0029055964 scopus 로고
    • Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
    • Giaid A, Saleh D. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N Engl J Med. 1995;333:214-221.
    • (1995) N Engl J Med , vol.333 , pp. 214-221
    • Giaid, A.1    Saleh, D.2
  • 28
    • 0028832852 scopus 로고
    • Endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension
    • Xue C, Johns RA. Endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N Engl J Med. 1995;333: 1642-1644.
    • (1995) N Engl J Med , vol.333 , pp. 1642-1644
    • Xue, C.1    Johns, R.A.2
  • 29
    • 0028341843 scopus 로고
    • Expression of nitric oxide synthase immunoreactivity by interstitial cells of the canine proximal colon
    • Xue C, Pollock J, Schmidt HHHW, Ward SM, Sanders KM. Expression of nitric oxide synthase immunoreactivity by interstitial cells of the canine proximal colon. J Auton Nerv Syst. 1994;49:1-14.
    • (1994) J Auton Nerv Syst , vol.49 , pp. 1-14
    • Xue, C.1    Pollock, J.2    Schmidt, H.H.H.W.3    Ward, S.M.4    Sanders, K.M.5
  • 30
    • 0030020020 scopus 로고    scopus 로고
    • Developmental expression of NOSs in fetal rat lung: Implications for transitional circulation and pulmonary angiogenesis
    • Xue C, Reynolds PR, Johns RA. Developmental expression of NOSs in fetal rat lung: implications for transitional circulation and pulmonary angiogenesis. Am J Physiol. 1996:L88-L100.
    • (1996) Am J Physiol
    • Xue, C.1    Reynolds, P.R.2    Johns, R.A.3
  • 31
    • 0029112111 scopus 로고
    • Halothane, enflurane, and isoflurane do not affect the basal or agonist-stimulated activity of partially isolated soluble and particulate guanylyl cyclases of rat brain
    • Zuo Z, Johns RA. Halothane, enflurane, and isoflurane do not affect the basal or agonist-stimulated activity of partially isolated soluble and particulate guanylyl cyclases of rat brain. Anesthesiology. 1995; 83:395-404.
    • (1995) Anesthesiology , vol.83 , pp. 395-404
    • Zuo, Z.1    Johns, R.A.2
  • 32
    • 0028519806 scopus 로고
    • Hypoxia and endothelial-smooth muscle cell interactions in the lung
    • Kourembanas S, Bernfield M. Hypoxia and endothelial-smooth muscle cell interactions in the lung. Am J Respir Cell Mol Biol. 1994; 11:373-374.
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 373-374
    • Kourembanas, S.1    Bernfield, M.2
  • 33
    • 0024805433 scopus 로고
    • Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia
    • Johns RA, Linden JM, Peach MJ. Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia. Circ Res. 1989;65:1508-1515.
    • (1989) Circ Res , vol.65 , pp. 1508-1515
    • Johns, R.A.1    Linden, J.M.2    Peach, M.J.3
  • 34
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromocyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8-bromocyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest. 1989;83:1774-1777.
    • (1989) J Clin Invest , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2
  • 35
    • 0028095289 scopus 로고
    • Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells
    • Hassid A, Arabshahi H, Bourcier T, Phaursi GS, Matthews C. Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells. Am J Physiol. 1994;267:H1040-H1048.
    • (1994) Am J Physiol , vol.267
    • Hassid, A.1    Arabshahi, H.2    Bourcier, T.3    Phaursi, G.S.4    Matthews, C.5
  • 40
    • 0027176563 scopus 로고
    • Cloning of inducible nitric oxide synthase in rat vascular smooth muscle cells
    • Nunokawa Y, Nobuhiro I, Tanaka S. Cloning of inducible nitric oxide synthase in rat vascular smooth muscle cells. Biochem Biophys Res Commun. 1993;191:89-94.
    • (1993) Biochem Biophys Res Commun , vol.191 , pp. 89-94
    • Nunokawa, Y.1    Nobuhiro, I.2    Tanaka, S.3
  • 41
    • 0028917561 scopus 로고
    • Structural diversity in the 5′-untranslated region of cytokine-stimulated human inducible nitric oxide synthase mRNA
    • Chu SC, Wu H, Banks TC, Eissa NT, Moss J. Structural diversity in the 5′-untranslated region of cytokine-stimulated human inducible nitric oxide synthase mRNA. J Biol Chem. 1995;270:10625-10630.
    • (1995) J Biol Chem , vol.270 , pp. 10625-10630
    • Chu, S.C.1    Wu, H.2    Banks, T.C.3    Eissa, N.T.4    Moss, J.5
  • 42
    • 0028557243 scopus 로고
    • Immunohistochemical demonstration of a paracrine role of nitric oxide in bronchial function
    • Rengasamy A, Xue C, Johns RA. Immunohistochemical demonstration of a paracrine role of nitric oxide in bronchial function. Am J Physiol. 1994;267:L704-L711.
    • (1994) Am J Physiol , vol.267
    • Rengasamy, A.1    Xue, C.2    Johns, R.A.3
  • 44
    • 0028118896 scopus 로고
    • Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression
    • Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res. 1994;74:349-353.
    • (1994) Circ Res , vol.74 , pp. 349-353
    • Sessa, W.C.1    Pritchard, K.2    Seyedi, N.3    Wang, J.4    Hintze, T.H.5
  • 46
    • 0028211799 scopus 로고
    • Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats
    • Isaacson TC, Hampl V, Weir K, Nelson DP, Archer SL. Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats. J Appl Physiol. 1994;76:933-940.
    • (1994) J Appl Physiol , vol.76 , pp. 933-940
    • Isaacson, T.C.1    Hampl, V.2    Weir, K.3    Nelson, D.P.4    Archer, S.L.5
  • 47
    • 0028894427 scopus 로고
    • Marked induction of calcium-independent nitric oxide synthase activity after focal cerebral ischemia
    • Iadecola C, Xu X, Zhang F, El-Fakahany EE, Ross ME. Marked induction of calcium-independent nitric oxide synthase activity after focal cerebral ischemia. J Cereb Blood Flow Metab. 1995; 15:52-59.
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 52-59
    • Iadecola, C.1    Xu, X.2    Zhang, F.3    El-Fakahany, E.E.4    Ross, M.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.