-
1
-
-
0025770443
-
Nitric oxide synthase in native and cultured endothelial cells: Calcium/calmodulin and tetrahydrobiopterin are co-factors
-
Mülsch A, Busse R. Nitric oxide synthase in native and cultured endothelial cells: calcium/calmodulin and tetrahydrobiopterin are co-factors. J Cardiovasc Pharmacol 1991;17(suppl 3):S52-6.
-
(1991)
J Cardiovasc Pharmacol
, vol.17
, Issue.3 SUPPL.
-
-
Mülsch, A.1
Busse, R.2
-
2
-
-
0026556496
-
Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells
-
Schmidt K, Werner ER, Mayer B, Wachter H, Kukovetz WR. Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells. Biochem J 1992;281:297-300.
-
(1992)
Biochem J
, vol.281
, pp. 297-300
-
-
Schmidt, K.1
Werner, E.R.2
Mayer, B.3
Wachter, H.4
Kukovetz, W.R.5
-
3
-
-
0026584089
-
2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase
-
2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J 1992;281:627-30.
-
(1992)
Biochem J
, vol.281
, pp. 627-630
-
-
Heinzel, B.1
John, M.2
Klatt, P.3
Böhme, E.4
Meyer, B.5
-
4
-
-
0024360417
-
Tetrahydrobiopterin metabolism in the streptozotocin induced diabetic state in rats
-
Hamon CG, Culter P, Blair JA. Tetrahydrobiopterin metabolism in the streptozotocin induced diabetic state in rats. Clin Chim Acta 1989;181:249-54.
-
(1989)
Clin Chim Acta
, vol.181
, pp. 249-254
-
-
Hamon, C.G.1
Culter, P.2
Blair, J.A.3
-
5
-
-
0000489612
-
Oxidative stress in diabetic blood vessels
-
Pieper GM. Oxidative stress in diabetic blood vessels. FASEB J 1995;9:A891.
-
(1995)
FASEB J
, vol.9
-
-
Pieper, G.M.1
-
6
-
-
0015370583
-
Steric aspects of adrenergic drugs. VIII. Alpha adrenergic receptors of mammalian aorta
-
Patil PN, Fudge K, Jacobowitz D. Steric aspects of adrenergic drugs. VIII. Alpha adrenergic receptors of mammalian aorta. Eur J Pharmacol 1972;19:79-87.
-
(1972)
Eur J Pharmacol
, vol.19
, pp. 79-87
-
-
Patil, P.N.1
Fudge, K.2
Jacobowitz, D.3
-
7
-
-
0024244043
-
Adrenergic nerve function and contractile activity of the caudal artery of the streptozotocin diabetic rat
-
Hart JL, Freas W, McKenzie JE, Muldoon SM. Adrenergic nerve function and contractile activity of the caudal artery of the streptozotocin diabetic rat. J Auton Nerv Syst 1988;25:49-57.
-
(1988)
J Auton Nerv Syst
, vol.25
, pp. 49-57
-
-
Hart, J.L.1
Freas, W.2
McKenzie, J.E.3
Muldoon, S.M.4
-
9
-
-
0023713429
-
Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta
-
Pieper GM, Gross GJ. Oxygen free radicals abolish endothelium-dependent relaxation in diabetic rat aorta. Am J Physiol 1988;255: H825-33.
-
(1988)
Am J Physiol
, vol.255
-
-
Pieper, G.M.1
Gross, G.J.2
-
10
-
-
0024344494
-
Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats
-
Kamata K, Miyata N, Kasuya Y. Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats. J Pharmacol Exp Ther 1989;249:890-4.
-
(1989)
J Pharmacol Exp Ther
, vol.249
, pp. 890-894
-
-
Kamata, K.1
Miyata, N.2
Kasuya, Y.3
-
11
-
-
0028962722
-
Amelioration by L-arginine of a dysfunctional arginine/nitric oxide pathway in diabetic in diabetic endothelium
-
Pieper GM, Peltier BA. Amelioration by L-arginine of a dysfunctional arginine/nitric oxide pathway in diabetic in diabetic endothelium. J Cardiovasc Pharmacol 1995;25:397-403.
-
(1995)
J Cardiovasc Pharmacol
, vol.25
, pp. 397-403
-
-
Pieper, G.M.1
Peltier, B.A.2
-
12
-
-
0028805444
-
Syngeneic pancreatic islet transplantation reverses endothelial dysfunction in experimental diabetes
-
Pieper GM, Jordan M, Adams MB, Roza AM. Syngeneic pancreatic islet transplantation reverses endothelial dysfunction in experimental diabetes. Diabetes 1995;44:1106-13.
-
(1995)
Diabetes
, vol.44
, pp. 1106-1113
-
-
Pieper, G.M.1
Jordan, M.2
Adams, M.B.3
Roza, A.M.4
-
13
-
-
0028924952
-
Kinetics of tetrahydrobiopterin-induced oxidation of nitric oxide
-
Mayer B, Klatt P, Werner ER, Schmidt K. Kinetics of tetrahydrobiopterin-induced oxidation of nitric oxide. J Biol Chem 1995;270:655-9.
-
(1995)
J Biol Chem
, vol.270
, pp. 655-659
-
-
Mayer, B.1
Klatt, P.2
Werner, E.R.3
Schmidt, K.4
-
14
-
-
0022828334
-
Attenuation of endothelium-dependent relaxation in aorta from diabetic rats
-
Oyama Y, Kawasaki H, Hattori Y, Kanno M. Attenuation of endothelium-dependent relaxation in aorta from diabetic rats. Eur J Pharmacol 1986;131:75-8.
-
(1986)
Eur J Pharmacol
, vol.131
, pp. 75-78
-
-
Oyama, Y.1
Kawasaki, H.2
Hattori, Y.3
Kanno, M.4
-
15
-
-
0024309747
-
Impairment of endothelium-dependent relaxation and changes on levels of cyclic GMP in aorta from streptozocin-induced diabetic rats
-
Kamata K, Miyata N, Kasuya Y. Impairment of endothelium-dependent relaxation and changes on levels of cyclic GMP in aorta from streptozocin-induced diabetic rats. Br J Pharmacol 1989;97:614-8.
-
(1989)
Br J Pharmacol
, vol.97
, pp. 614-618
-
-
Kamata, K.1
Miyata, N.2
Kasuya, Y.3
-
17
-
-
0026023120
-
Mechanism of impaired responses of cerebral arterioles during diabetes mellitus
-
Mayhan WG, Simmons LK, Sharpe GM. Mechanism of impaired responses of cerebral arterioles during diabetes mellitus. Am J Physiol 1991;260:H319-26.
-
(1991)
Am J Physiol
, vol.260
-
-
Mayhan, W.G.1
Simmons, L.K.2
Sharpe, G.M.3
-
18
-
-
0028045638
-
Endothelial dysfunction in mesenteric resistance arteries of diabetic rat: Role of free radicals
-
Diederich D, Skopec J, Diederich A, Dai FX. Endothelial dysfunction in mesenteric resistance arteries of diabetic rat: role of free radicals. Am J Physiol 1994;266:H1153-61.
-
(1994)
Am J Physiol
, vol.266
-
-
Diederich, D.1
Skopec, J.2
Diederich, A.3
Dai, F.X.4
-
19
-
-
0027381832
-
Impaired endothelium-dcpendent vasodilation in patients with insulin-dependent diabetes mellitus
-
Johnstone MT, Creager SJ, Scales KM, Cusco JA, Lee BK, Creager MA. Impaired endothelium-dcpendent vasodilation in patients with insulin-dependent diabetes mellitus. Circulation 1993;88: 2510-6.
-
(1993)
Circulation
, vol.88
, pp. 2510-2516
-
-
Johnstone, M.T.1
Creager, S.J.2
Scales, K.M.3
Cusco, J.A.4
Lee, B.K.5
Creager, M.A.6
-
20
-
-
0026684462
-
Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus
-
McVeigh GE, Brennan GM, Johnston GD, et al. Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 1992; 35:771-6.
-
(1992)
Diabetologia
, vol.35
, pp. 771-776
-
-
McVeigh, G.E.1
Brennan, G.M.2
Johnston, G.D.3
-
21
-
-
0026736722
-
Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals
-
Langenstroer P, Pieper GM. Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals. Am J Physiol 1992;263:H257-65.
-
(1992)
Am J Physiol
, vol.263
-
-
Langenstroer, P.1
Pieper, G.M.2
-
23
-
-
0026759488
-
Free radicals mediate endothelial cell dysfunction caused by elevated glucose
-
Tesfamariam B, Cohen RA. Free radicals mediate endothelial cell dysfunction caused by elevated glucose. Am J Physiol 1992;263: H321-6.
-
(1992)
Am J Physiol
, vol.263
-
-
Tesfamariam, B.1
Cohen, R.A.2
-
24
-
-
0030058769
-
Evaluation of the mechanism of endothelial dysfunction in the genetically-diabetic BB rat
-
Pieper GM, Moore-Hilton G, Roza AM. Evaluation of the mechanism of endothelial dysfunction in the genetically-diabetic BB rat. Life Sci 1996;58:PL147-52.
-
(1996)
Life Sci
, vol.58
-
-
Pieper, G.M.1
Moore-Hilton, G.2
Roza, A.M.3
-
25
-
-
0026738167
-
Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: Role of polyol pathway
-
Cameron NE, Cotter MA. Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: role of polyol pathway. Diabetologia 1992;35:1011-9.
-
(1992)
Diabetologia
, vol.35
, pp. 1011-1019
-
-
Cameron, N.E.1
Cotter, M.A.2
-
26
-
-
0026490369
-
Endothelium-dependent increase in vascular sensitivity to phenylephrine in long-term streptozotocin diabetic rat aorta
-
Chang KSK, Stevens WC. Endothelium-dependent increase in vascular sensitivity to phenylephrine in long-term streptozotocin diabetic rat aorta. Br J Pharmacol 1992;107:983-90.
-
(1992)
Br J Pharmacol
, vol.107
, pp. 983-990
-
-
Chang, K.S.K.1
Stevens, W.C.2
-
27
-
-
0029877288
-
2+, on basal and agonist-stimulated nitric oxide activity
-
2+, on basal and agonist-stimulated nitric oxide activity. Biochem Biophys Res Commun 1996;219:584-90.
-
(1996)
Biochem Biophys Res Commun
, vol.219
, pp. 584-590
-
-
Pieper, G.M.1
Lai, C.S.2
-
28
-
-
0027992650
-
Tetrahydrobiopterin as another EDRF in man
-
Schaffner A, Blau N, Schneemann M, Steurer J, Edgell C-JS, Schoedon G. Tetrahydrobiopterin as another EDRF in man. Biochem Biophys Res Commun 1994;205:516-23.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 516-523
-
-
Schaffner, A.1
Blau, N.2
Schneemann, M.3
Steurer, J.4
Edgell, C.-J.S.5
Schoedon, G.6
-
29
-
-
0026474595
-
(6R)-5,6,7,8-Tetradhyro-L-biopterin modulates nitric oxide-associated soluble guanylate cyclase activity in the rat cerebellum
-
Nunokawa Y, Ishihara T, Kanai T, Noguchi T. (6R)-5,6,7,8-Tetradhyro-L-biopterin modulates nitric oxide-associated soluble guanylate cyclase activity in the rat cerebellum. Arch Biochem Biophys 1992;298:726-30.
-
(1992)
Arch Biochem Biophys
, vol.298
, pp. 726-730
-
-
Nunokawa, Y.1
Ishihara, T.2
Kanai, T.3
Noguchi, T.4
-
30
-
-
0025968786
-
Purification of a soluble isoform of guanylyl cyclase-activating factor synthase
-
Schmidt HHH, Pollock JS, Nakane M, Gorsky LD, Förstermann U, Murad F. Purification of a soluble isoform of guanylyl cyclase-activating factor synthase. Proc Natl Acad Sci USA 1991;88: 365-9.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 365-369
-
-
Schmidt, H.H.H.1
Pollock, J.S.2
Nakane, M.3
Gorsky, L.D.4
Förstermann, U.5
Murad, F.6
-
31
-
-
0020610950
-
Hormonal regulation of guanosine triphosphate cyclohydrolase activity and biopterin levels in the rat adrenal cortex
-
Abou-Donia MM, Duch DS, Nichol CA, Viveros OH. Hormonal regulation of guanosine triphosphate cyclohydrolase activity and biopterin levels in the rat adrenal cortex. Endocrinology 1983; 112:2088-94.
-
(1983)
Endocrinology
, vol.112
, pp. 2088-2094
-
-
Abou-Donia, M.M.1
Duch, D.S.2
Nichol, C.A.3
Viveros, O.H.4
-
32
-
-
0029043644
-
In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide
-
Mayer B, Werner WR. In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn-Schmiedebergs Arch Pharmacol 1995;351:453-63.
-
(1995)
Naunyn-Schmiedebergs Arch Pharmacol
, vol.351
, pp. 453-463
-
-
Mayer, B.1
Werner, W.R.2
-
33
-
-
0025826860
-
Tetrahydrobiopterin, a co-factor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine
-
Giovanelli J, Campos KL, Kaufman S. Tetrahydrobiopterin, a co-factor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine. Proc Natl Acad Sci USA 1991;88:7091-5.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7091-7095
-
-
Giovanelli, J.1
Campos, K.L.2
Kaufman, S.3
-
34
-
-
0027441142
-
Macrophage nitric oxide synthase subunits: Purification, characterization and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme
-
Baek KJ, Thiel BA, Lucas S, Stuehr DJ. Macrophage nitric oxide synthase subunits: purification, characterization and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme. J Biol Chem 1993;268:21120-9.
-
(1993)
J Biol Chem
, vol.268
, pp. 21120-21129
-
-
Baek, K.J.1
Thiel, B.A.2
Lucas, S.3
Stuehr, D.J.4
-
35
-
-
0028302095
-
The pteridine binding site of brain nitric oxide synthase-tetrahydrobiopterin binding kinetics, specificity and allosteric interaction with the substrate domain
-
Klatt P, Schmid M, Leopold E, Schmidt K, Werner ER, Mayer B. The pteridine binding site of brain nitric oxide synthase-tetrahydrobiopterin binding kinetics, specificity and allosteric interaction with the substrate domain. J Biol Chem 1994;269:13861-6.
-
(1994)
J Biol Chem
, vol.269
, pp. 13861-13866
-
-
Klatt, P.1
Schmid, M.2
Leopold, E.3
Schmidt, K.4
Werner, E.R.5
Mayer, B.6
-
36
-
-
0028140141
-
Inhibitors of brain nitric oxide synthase: Binding kinetics, metabolism and enzyme inactivation
-
Klatt P, Schmidt K, Brunner F, Mayer B. Inhibitors of brain nitric oxide synthase: binding kinetics, metabolism and enzyme inactivation. J Biol Chem 1994;269:1674-80.
-
(1994)
J Biol Chem
, vol.269
, pp. 1674-1680
-
-
Klatt, P.1
Schmidt, K.2
Brunner, F.3
Mayer, B.4
-
37
-
-
0028897734
-
Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hphl mouse
-
Brand MP, Heales SJR, Land JM, Clark JB. Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hphl mouse. J Inher Metab Dis 1995;18:33-9.
-
(1995)
J Inher Metab Dis
, vol.18
, pp. 33-39
-
-
Brand, M.P.1
Heales, S.J.R.2
Land, J.M.3
Clark, J.B.4
-
38
-
-
0028874207
-
The protective effect of tetrahydrobiopterin on the nitric oxide-mediated inhibition of purified nitric oxide synthase
-
Hyun J, Komori Y, Chaudhuri G, Ignarro LJ, Fukuto JM. The protective effect of tetrahydrobiopterin on the nitric oxide-mediated inhibition of purified nitric oxide synthase. Biochem Biophys Res Commun 1995;206:380-6.
-
(1995)
Biochem Biophys Res Commun
, vol.206
, pp. 380-386
-
-
Hyun, J.1
Komori, Y.2
Chaudhuri, G.3
Ignarro, L.J.4
Fukuto, J.M.5
-
39
-
-
0028813306
-
Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries
-
Cosentino F, Katusic ZS. Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries. Circulation 1995;91:139-44.
-
(1995)
Circulation
, vol.91
, pp. 139-144
-
-
Cosentino, F.1
Katusic, Z.S.2
-
40
-
-
0029130546
-
Peroxidative stress in diabetic blood vessels: Reversal by pancreatic islet transplantation
-
Pieper GM, Jordan M, Dondlinger LA, Adams MB, Roza AM. Peroxidative stress in diabetic blood vessels: reversal by pancreatic islet transplantation. Diabetes 1995;44:884-9.
-
(1995)
Diabetes
, vol.44
, pp. 884-889
-
-
Pieper, G.M.1
Jordan, M.2
Dondlinger, L.A.3
Adams, M.B.4
Roza, A.M.5
|