Pranidipine Enhances the Action of Nitric Oxide Released From Endothelial Cells

Hypertension

Volumn 35, Issue 1, 2000, Pages 82-

  Yang, Jin ^a   Fukuo, Keisuke ^a   Morimoto, Shigeto ^a   Niinobu, Tadaaki ^a   Suhara, Toshimitsu ^a   Ogihara, Toshio ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Calcium antagonists; Endothelin; Nitric oxide; Superoxide

Indexed keywords

AMLODIPINE; CALCIUM ANTAGONIST; DIHYDROPYRIDINE DERIVATIVE; ENDOTHELIN; NIFEDIPINE; NITRIC OXIDE; PRANIDIPINE; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CELL CULTURE; DRUG POTENCY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HEART VENTRICLE WALL; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE;

AMLODIPINE; ANIMALS; AORTA, THORACIC; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; COCULTURE TECHNIQUES; CYCLIC GMP; DIHYDROPYRIDINES; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; HUMANS; HYPERTENSION; MALE; MUSCLE, SMOOTH, VASCULAR; NIFEDIPINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 0033978264     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/01.HYP.35.1.82     Document Type: Article

References (17)

1. Weinstein DB, Heider JG. Antiatherogenic properties of calcium antagonists. Am J Med. 1989; 86:27-32.
2. Packer M, O’Connor CM, Ghali JK, Pressler ML, Carson PE, Belkin RN, Miller AB, Neuberg GW, Frid D, Wertheimer JH, Cropp AB, DeMets DL. Effects of amlodipine on morbidity and mortality in severe chronic heart failure: Prospective Randomized Amlodipine Survival Evaluation Study Group. N Engl J Med. 1996; 335:1107-1114.
3. Zhang X, Hintze TH. Amlodipine releases nitric oxide from canine coronary microvessels: an unexpected mechanism of action of a calcium channel-blocking agent. Circulation. 1998; 97:576-580.
4. Nakayama N, Ikezono K, Ohura M, Yabuuchi Y. Effects of the new long-acting dihydropyridine calcium antagonist pranidipine on the endothelium-dependent relaxation in isolated rat aorta in vitro. Arzneimittelforschung. 1993; 43:1266-1270.
5. Jiang B, Morimoto S, Fukuo K, Hirotani A, Tamatani M, Nakahashi A, Nishibe A, Niinobu T, Hata S, Chen S, Ogihara T. Parathyroid hormone-related protein inhibits endothelin-1 production. Hypertension. 1996; 27 (pt 1):360-363.
6. Fukuo K, Hata S, Suhara T, Nakahashi T, Shinto Y, Tsujimoto Y, Morimoto S, Ogihara T. Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle. Hypertension. 1996; 27:823-826.
7. Fukuo K, Inoue T, Morimoto S, Nakahashi T, Yasuda O, Kitano S, Sasada R, Ogihara T. Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells: a possible mechanism of neovascularization in atherosclerotic plaques. J Clin Invest. 1995; 95:669-676.
8. Nebot C, Moutet M, Huet P, Xu J-Z, Yadan J-C, Chaudiere J. Spectrophotometric assay of superoxide dismutase activity based on the activated autoxidation of a tetracyclic catechol. Anal Biochem. 1993; 214:442-451.
9. Boulanger C, Luscher TF. Release of endothelin from the porcine aorta: inhibition by endothelium-derived nitric oxide. J Clin Invest. 1990; 85:587-590.
10. Nakazono K, Wartanabe N, Matsumoto K, Sasaki J, Satao T, Inoue M. Does superoxide underlie the pathogenesis of hypertension? Proc Natl Acad Sci U S A. 1991; 88:10045-10048.
11. Panza JA, Casino PR, Kilcoyne CM, Quyyumi AA. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension. Circulation. 1993; 87:1468-1474.
12. Tschudi MR, Mesaros S, Luscher TF, Malinski T. Direct in situ measurement of nitric oxide in mesenteric resistance arteries: increased decomposition by superoxide in hypertension. Hypertension. 1996; 27:32-35.
13. Terada LS, Willingham IR, Rosandich ME, Leff JA, Kindt GW, Repine JE. Generation of superoxide anion by brain endothelial cell xanthine oxidase. J Cell Physiol. 1991; 148:191-196.
14. Mohazzab KM, Kaminski PM, Wolin MS. NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium. Am J Physiol. 1994; 266:H2568-H2572.
15. Hishikawa K, Luscher TF. Pulsatile stretch stimulates superoxide production in human aortic endothelial cells. Circulation. 1997; 96:3610-3616.
16. Chen L, Haught WH, Yang B, Saldeen TGP, Parathasarathy S, Mehta JL. Preservation of endogenous antioxidant activity and inhibition of lipid peroxidation as common mechanism of antiatherosclerotic effects of vitamin E, lovastatin and amlodipine. J Am Coll Cardiol. 1997; 30:569-575.
17. Kishi Y, Watanabe T, Makita T, Sakita S, Watanabe R, Ashikaga T, Numano F. Effect of nifedipine on cyclic GMP turnover in cultured coronary smooth muscle cells. J Cardiovasc Pharmacol. 1995; 26:590-595.