Restoration of nitric oxide availability after calcium antagonist treatment in essential hypertension

Hypertension

Volumn 37, Issue 3, 2001, Pages 943-948

  Taddei, Stefano ^a   Virdis, Agostino ^a   Ghiadoni, Lorenzo ^a   Magagna, Armando ^a   Favilla, Stefania ^a   Pompella, Alfonso ^b   Salvetti, Antonio ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

Antioxidants; Calcium antagonists; Endothelium; Endothelium derived factors; Free radicals; Hypertension, essential; Nitric oxide

Indexed keywords

ACETYLCHOLINE; ANTIOXIDANT; ASCORBIC ACID; CALCIUM ANTAGONIST; ENDOTHELIUM DERIVED RELAXING FACTOR; FREE RADICAL; ISOPROSTANE; LIPID PEROXIDE; N(G) METHYLARGININE; NIFEDIPINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ESSENTIAL HYPERTENSION; FEMALE; HUMAN; MALE; OXIDATIVE STRESS; PLETHYSMOGRAPHY; PRIORITY JOURNAL; VASODILATATION;

EID: 0035100975     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.37.3.943     Document Type: Article

References (38)

1. Vascular endothelial cells synthesise nitric oxide from L-arginine
2. Endothelium-dependent contractions to ACh in the aorta of spontaneously hypertensive rats
3. Superoxide anion is an endothelium-derived contracting factor
4. Indirect evidence for the release of endothelium-derived relaxing factor in the human forearm circulation in vivo: Blunted response in essential hypertension
5. Abnormal endothelium dependent vascular relaxation in patients with essential hypertension
6. Vasodilation to ACh in primary and secondary forms of human hypertension
7. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension
8. Effect of insulin on ACh-induced vasodilation in normotensive subjects and patients with essential hypertension
9. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension
10. Role of products of univalent reduction of oxygen in hypertensive vascular injury
11. The pathogenesis of atherosclerosis: A perspective for the 1990s
12. Antioxidant effects of calcium channel blockers against free radical injury in endothelial cells
13. In vitro antioxidant activity of calcium antagonists against LDL oxidation compared with α-tocopherol
14. The measurement of volume changes in human limbs
15. SNP and other smooth muscle relaxants increase cyclic GMP levels in rat ductus deferens
16. Cyclosporine A increases nitric oxide activity in vivo
17. Ferrous ione oxidation in presence of ferric ion indicator xylenol orange for measurement for hydroperoxides
18. Immunological characterization of urinary 8-epi-prostaglandin F2α excretion in man
19. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay
20. Structure and function of resistance arteries of hypertensive patients treated with β-blocker or a calcium channel antagonist
21. Normalization of abnormal coronary vasomotion by calcium antagonists in patients with hypertension
22. Lacidipine restores endothelium-dependent vasodilation in essential hypertensive patients
23. G-monomethyl-L-arginine in patients with essential hypertension
24. Vasodilation to bradykinin is mediated by an ouabain-sensitive pathway as a compensatory mechanism for impaired NO availability in essential hypertensive patients
25. Effect of captopril and enalapril on endothelial function in hypertensive patients
26. Effect of cilazapril on vascular structure and function in essential hypertension
27. Intracellular calcium, currents and stimulus-response coupling in endothelial cells
28. ++-antagonists
29. Antihypertensive therapy augments endothelium-dependent relaxations in coronary arteries of spontaneously hypertensive rats
30. Ascorbate is an outstanding antioxidant in human blood plasma
31. The antioxidant role of vitamin C
32. Nifedipine improves nitric oxide-mediated vasodilation in hypercholesterolemia, independent of an effect on blood pressure or plasma lipids
33. Vitamin C improves endothelium-dependent vasodilation in forearm resistance vessels in humans with hypercholesterolemia
34. Treatment of hypertension with ascorbic acid
35. Retardation of angiographic progression of coronary artery disease by nifedipine: Results of the International Nifedipine Trial on Antiatherosclerotic Therapy (INTACT)
36. A controlled clinical trial to assess the effect of a calcium channel blocker on the progression of coronary atherosclerosis
37. Effects of calcium antagonism and HMG-Co-enzyme reductase inhibition on endothelial function and atherosclerosis: Rationale and outline of the ENCORE Trials