The molecular neurobiology of stress - Evidence from genetic and epigenetic models

Behavioural Pharmacology

Volumn 12, Issue 6-7, 2001, Pages 381-427

  Steckler, T ^a  

^a JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

Anxiety; Circadian rhythm; Corticosteroids; CRH; CRH related peptides; Gene targeting; Glucocorticoid; HPA axis; Learning; Memory; Motivation; Stress; Transcription factors; Transgenesis; Vasopressin

Indexed keywords

CORTICOSTEROID; CORTICOTROPIN RELEASING FACTOR RECEPTOR; GENE PRODUCT; GLUCOCORTICOID; TRANSCRIPTION FACTOR; VASOPRESSIN;

ANIMAL BEHAVIOR; ANXIETY NEUROSIS; CIRCADIAN RHYTHM; GENE LOCUS; GENE TARGETING; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LEARNING; MEMORY; MOTIVATION; MULTIFACTORIAL INHERITANCE; NEUROBIOLOGY; NEUROTRANSMISSION; NONHUMAN; PATHOGENESIS; QUANTITATIVE TRAIT; REVIEW; STRESS; TRANSGENE;

EID: 0035215803     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008877-200111000-00002     Document Type: Review

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236. Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus
237. Stress-hyporesponsive period
238. Dexamethasone in the last week of pregnancy attenuates hippocampal glucocorticoid receptor gene expression and elevates blood pressure in the adult offspring in the rat
239. Opioid and nonopioid mechanisms of stress analgesia
240. Regulation of maternal behavior and offspring growth by paternally expressed Peg3
241. Corticotropin releasing hormone neurons in the paraventricular nucleus are direct targets for neuropeptide Y neurons in the arcuate nucleus: An anterograde-retrograde tracing study
242. Vasopressin, oxytocin, dynorphin, enkephalin, and corticotropin-releasing factor mRNA stimulation in the rat
243. Influence of steroids on the hypothalamic corticotropin-releasing factor and pre-proenkephalin mRNA response to stress
244. Impaired glucocorticoid receptor function in aberrant physiological responses to bacterial endotoxin
245. Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress
246. Maternal care, hippocampal synaptogenesis and cognitive development in rats
247. Influence of neonatal rearing conditions on stress-induced adrenocorticotropin responses and norepinephrine release in the hypothalamic paraventricular nucleus
248. Genomics, gene expression and DNA analysis
249. Repeated restraint stress prevents changes in corticotropin-releasing factor binding protein mRNA induced by acute stress
250. Regulation of 5-HT receptors and the hypothalamic-pituitary-adrenal axis. Implications for the neurobiology of suicide
251. Regulation of serotonin 1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: Implications for the neurobiology of depression
252. 2) agonists and antagonists on renin and corticosterone secretion
253. Ectopic expression of the CRF-binding protein: Minor impact on HPA axis regulation but induction of sexually dimorphic weight gain
254. Molecular and neuronal substrate for the selective attenuation of anxiety
255. Effect of acute stress on hippocampal glutamate levels and spectrin proteolysis in young and aged rats
256. Repeated stress causes reversible impairments of spatial memory performance
257. Stress-specific regulation of corticotropin-releasing hormone receptor expression in the paraventricular and supraoptic nuclei of the hypothalamus in the rat
258. Regulation of hypothalamic and pituitary corticotropin-releasing hormone receptor messenger ribonucleic acid by adrenalectomy and glucocorticoids
259. The acute effects of corticosteroids on cognition: Integration of animal and human model studies
260. The arginine vasopressin and corticotropin-releasing hormone gene transcription responses to varied frequencies of repeated stress in rats
261. Emergence of an isolated arginine vasopressin (AVP) response to stress after repeated restraint: A study both AVP and corticotropin-releasing hormone messenger ribonucleic acid (RNA) and heteronuclear RNA
262. Rapid changes in heteronuclear RNA for corticotropin-releasing hormone and arginine vasopressin in response to acute stress'
263. Vasopressin and corticotropin-releasing hormone gene responses to novel stress in rats adapted to repeated restraint
264. Hippocampal type I and type II corticosteroid receptor affinities are reduced in rats predisposed to develop amphetamine self-administration
265. Adoption reverses the long-term impairment in glucocorticoid feedback induced by prenatal stress
266. Interleukin-1 beta: A putative mediator of HPA axis hyperactivity in major depression?
267. Regulation of corticotropin-releasing hormone receptor messenger ribonucleic acid in the rat brain and pituitary by glucocorticoids and stress
268. Altered expression of type 2 CRH receptor mRNA in the VMH by glucocorticoids and starvation
269. Altered emotional and locomotor responses in mice deficient in the transcription factor CREM
270. Novelty acquisition is associated with induction of hippocampal long-term depression
271. Neuroplasticity and cellular resilience in mood disorders
272. Regulation of corticotropin-releasing factor type 1 (CRF1) receptor messenger ribonucleic acid in the paraventricular nucleus of the rat hypothalamus by exogenous CRF
273. Identification of projections from the central nucleus of the amygdala to the paraventricular nucleus of the hypothalamus which are immunoreactive for corticotropin-releasing hormone in the rat
274. Pharmacological characterisation of 5-HT receptors positively coupled to adenylyl cyclase in the rat hippocampus
275. Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia
276. Central administration of prolactin-releasing peptide stimulates oxytocin release in rats
277. Prolactin-releasing peptide as a novel stress mediator in the central nervous system
278. A review of psychoendocrine research on the pituitary-adrenal cortical system
279. Corticotropin-releasing factor but not urocortin is involved in adrenalectomy-induced adenocorticotropin release
280. 1A receptor agonists
281. Regulation of pituitary corticotropin-releasing hormone-binding protein messenger ribonucleic acid levels by restrain stress and adrenalectomy
282. Sex-dependent effects of prenatal stress on the development of brain corticosteroid receptor systems and hypothalamic-pituitary-adrenal responses to stress
283. 5'-Heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: Differential regulation of variant transcripts by early-life events
284. Allostasis and allostatic load
285. Effects of psychological stress on male reproduction: A review
286. Chronic social stress reduces dendritic arbors in CA3 of hippocampus and decreases binding to serotonin transporter sites
287. The effects of early postnatal handling on the development of hippocampal glucocorticoid receptors: Temporal parameters
288. Neonatal handling alters adrenocortical negative feedback sensitivity and hippocampal type II glucocorticoid receptor binding in the rat
289. Early environmental regulation of forebrain glucocorticoid receptor gene expression: Implications for adrenocortical response to stress
290. Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: The effects of thyroid hormones and serotonin
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299. Effect of sectioning of the fornix on diurnal fluctuation in plasma corticosterone levels in the rat
300. Identification of a sex-specific quantitative trait locus mediating nonopioid stress-induced analgesia in female mice
301. Long-term antidepressant treatment reduces behavioural deficits in transgenic mice with impaired glucocorticoid receptor function
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303. Effects of stress and corticosterone on gene expression of brain-derived neurotrophic factor in the rat hippocampus: Actions of antidepressant treatments
304. Neuropeptide regulation of appetite and weight
305. Effect of neuropeptide Y on ingestive behaviors in the rat
306. TMT, a predator odor, elevates mesoprefrontal dopamine metabolic activity and disrupts short-term working memory in the rat
307. Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need
308. The 5′-flanking region of the mouse adenylyl cyclase type VIII gene imparts tissue-specific expression in transgenic mice
309. Disruption of feeding behavior in CRH receptor 1-deficient nice is dependent on glucocorticoids
310. Selective activation of the hypothalamic vasopressinergic system in mice deficient for the corticotropin-releasing hormone receptor 1 is dependent on glucocorticoids
311. Expression of crhr1 and crhr2 in mouse pituitary and adrenal gland: Implications for HPA system regulation
312. Pituitary adenylate cyclase-activating polypeptide stimulates arginine vasopressin release in conscious rats
313. Rewarding effects of opiates are absent in mice lacking the receptor for substance P
314. 1A receptor-mediated temperature and corticosterone responses in mice
315. 2 receptor-mediated temperature and corticosterone responses
316. Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor
317. Brain oxytocin inhibits basal and stress-induced activity of the hypothalamo-pituitary-adrenal axis in male and female rats: Partial action within the paraventricular nucleus
318. Exposure to acute stress induces brain interleukin-1 protein in the rat
319. Long-lasting effects of acute stress on CRFR1, pCREB and Fos in the mouse hippocampus
320. Stimulation of hypothalamic β-endorphin and dynorphin release by corticotropin-releasing factor
321. Enhanced tyrosine hydroxylation in hippocampus of chronically stressed rats upon exposure to a novel stressor
322. Role of tachykinins in the regulation of the hypothalamo-pituitary-adrenal axis
323. Urocortin in the ventromedial hypothalamic nucleus acts as an inhibitor of feeding behavior in rats
324. Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption
325. Facilitation of spatial learning requires DANN-binding of the glucocorticoid receptor
326. A receptor subunit mRNA levels in rat hippocampus
327. Distribution of V1a and V2 vasopressin receptor messenger ribonucleic acids in liver, kidney, pituitary and brain
328. Presynaptic localization of PACAP-type I-receptor in hippocampal and cerebellar mossy fibres
329. Impaired mossy fiber long-term potentiation and associative learning in pituitary adenylate cyclase activating polypeptide type I receptor-deficient mice
330. Altered emotional behavior in PACAP-type-I-receptor-deficient mice
331. Physiology and pharmacology of corticotropin-releasing factor
332. Luminal orientation and post-translational modifications of the liver microsomal 11 beta-hydroxysteroid dehydrogenase
333. Stress-induced norepinephrine release in hypothalamic paraventricular nucleus and pituitary-adrenocortical and sympathoadrenal activity: In vivo microdialysis studies
334. Brainstem hemisection decreases corticotropin-releasing hormone mRNA in the paraventricular nucleus but not in the central amygdaloid nucleus
335. Behavioral effects in the elevated plus maze of an NMDA antagonist injected into the dorsal hippocampus: Influence of restraint stress
336. Stress-induced expression of co-localized neuropeptides in hypothalamic and amygdaloid neurons
337. Increased anxiety of mice lacking the serotonin1A receptor
338. Stress regulation of adrenocorticosteroid receptor gene transcription and mRNA expression in rat hippocampus: Time-course analysis
339. The role of interleukin-6 in the human adrenal gland
340. Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
341. 1A receptor knockout mouse is normal
342. The effect of postnatal environment on stress-induced changes in hippocampal FOS-like immunoreactivity in adult rats
343. Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene
344. Differential regulation of synaptic proteins by stress
345. Glucocorticoids as biological substrates of reward: Physiological and pathophysiological implications
346. Corticosterone levels determine individual vulnerability to amphetamine self-administration
347. Glucocorticoids have state dependent effects on the mesencephalic dopaminerhgic transmission
348. Integrin subunit gene expression is regionally differentiated in adult brain
349. Opioid inhibition of immunoreactive corticotropin releasing factor secretion into the hypophysial-portal circulation of rats
350. Regulation of the hypophysiotropic factors mediating ACTH secretion
351. Pathways to the secretion of adrenocorticotropin: A view from the portal
352. Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats
353. Catecholaminergic modulation of corticotropin-releasing factor and adrenocorticotropin secretion
354. Neurohypophyseal peptides and social recognition in rats
355. Neurohypophyseal hormone receptors in the septum are implicated in social recognition in the rat
356. Cloning and characterization of the cDNAs for human and rat corticotropin releasing factor-binding proteins
357. The central distribution of a corticotropin-releasing factor (CRF)-binding protein predicts multiple sites and modes of interaction with CRF
358. Coexistence of corticotropin-releasing factor and enkephalin in the paraventricular nucleus of the rat
359. Antagonism of (+)WAY 100135 to behavioral, hypothermic and corticosterone effects induced by 8-OH-DPAT
360. Role of interleukin-1β in impairment of contextual fear conditioning caused by social isolation
361. Induction of IκBα mRNA expression in the brain by glucocorticoids: A negative feedback mechanism for immune-to-brain signaling
362. Regulation of pituitary vasopressin V1b receptor mRNA during stress in the rat
363. Modulation of hypothalamic-pituitary-adrenal function by transgenic expression of interleukin-6 in the CNS of mice
364. Mapping of provisional quantitative trait loci influencing temporal variation in locomotor activity in the LS × SS recombinant inbred strains
365. Exogenous BDNF protects against stress-induced learning impairments and attenuation of hippocampal LTP
366. Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: Differential roles of CRF receptors 1 and 2
367. 11β-Hydroxysteroid dehydrogenase in cultured hippocampal cells reactivates inert 11-dehydrocorticosterone, potentiating neurotoxicity
368. Serotonin receptor 1A knockout: An animal model of anxiety-related disorder
369. Effects of environmental enrichment on gene expression in the brain
370. Mice with an increased glucocorticoid receptor gene dosage show enhanced resistance to stress and endotoxic shock
371. Pituitary adenylate cyclase-activating polypeptide transduces through cAMP/PKA and PKC pathways and stimulates proopiomelanocortin gene transcription in mouse melanotropes
372. Two receptor systems for corticosterone in the rat brain: Microdistribution and differential occupation
373. Increased stress-induced adrenocorticotropin response after long-term intracerebroventricular treatment of rats with antisense mineralocorticoid receptor oligodeoxynucleotides
374. The brain mineralocorticoid receptor: Greedy for ligand mysterious in function
375. Urocortin II: A member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors
376. Involvement of corticotropin-releasing factor in the control of food intake and energy expenditure
377. Energy balance and lipid metabolism in transgenic mice bearing an antisense GCR gene construct
378. Solitary magnocellular neurons in the homozygous Brattleboro rat have vasopressin and glycopeptide immunoreactivity
379. Immune challenge and immobilization stress induce transcription of the gene encoding the CRF receptor in selective nuclei of the rat hypothalamus
380. Genetic analysis of the corticosterone response to ethanol in BXD recombinant inbred mice
381. Nucleotide sequence of a gene coding for ovine corticotropin-releasing factor and regulation of its mRNA level by glucocorticoids
382. Fear decrease in transgenic mice overexpressing bcl-2 in neurons
383. Transgenic mice with neuronal overexpression of Bcl-2 gene present navigation disabilities in a water task
384. Effects of glucocorticoid on corticotropin-releasing hormone gene regulation by second messenger pathways in NPLC and AtT-20 cells
385. Multifactorial regulation of the hypothalamo-pituitary-adrenal axis during development
386. Immunoreactive dynorphin-(1-8) and corticotropin-releasing factor in subpopulation of hypothalamic neurons
387. Central effects of CRF on metabolism and energy balance
388. Neonatal maternally deprived rats have as adults elevated basal pituitary-adrenal activity and enhanced susceptibility to apomorphine
389. Spatial memory in transgenic mice with impaired glucocorticoid receptor function
390. Stimulation of CRH-mediated ACTH secretion by central administration of neurotensin: Evidence for the participation of the paraventricular nucleus
391. Neuroendocrine aspects of primary endogenous depression. I. Cortisol secretory dynamics in patients and matched controls
392. A receptor subtypes
393. Corticotropic-releasing hormone and serotonin interact in the human brainstem: Behavioral implications
394. Pharmacological blockade or genetic deletion of substance P (NK1) receptors attenuates neonatal vocalisation in guinea-pigs and mice
395. Tyrosine hydroxylase mRNA levels in locus coeruleus of rats during adaptation to long-term immobilization stress exposure
396. Effect of novel stressors on gene expression of tyrosine hydroxylase and monoamine transporters in brainstem noradrenergic neurons of long-term repeatedly immobilized rats
397. Effect of restraint stress on food intake and body weight is determined by time of day
398. A critique of the vasopressin-memory hypothesis
399. Contrasting effects of vasopressin, desglycinamide-vasopressin and amphetamine on a delayed matching to position task in rats
400. Opposing effects of vasopressin on matching versus non-matching to position: Further evidence for response, not memory, modulation
401. Distribution and efferent projections of corticotropin-releasing factor-like immunoreactivity in the rat amygdaloid complex
402. 2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels
403. Autoradiographic and in situ hybridization localization of corticotropin-releasing factor 1 and 2 receptors in nonhuman primate brain
404. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function
405. Stress down regulates corticosterone receptors in a site-specific manner in the brain
406. Maturation of the adrenocortical stress response: Neuroendocrine control mechanisms and the stress hyporesponsive period
407. Glucocorticoid-sensitive hippocampal neurons are involved in terminating the adrenocortical stress response
408. Elevation of hypophyseal portal concentrations of adrenocorticotropin secretagogues after fornix transection
409. Glucocorticoid feedback inhibition of adrenocorticotropic hormone secretagogue release: Relationship to corticosteroid receptor occupancy in various limbic sites
410. Effects of long-term psychological stress on sexual behavior and brain catecholamine levels
411. Inherited hypothalamic diabetes insipidus in the Brattleboro strain of rats
412. Detection of corticotropin-releasing hormone receptor immunoreactivity in cholinergic, dopaminergic and noradrenergic neurons of the beasal forebrain and brainstem nuclei - Potential implication for arousal and attention
413. Mild deficits in mice lacking pituitary adenylate cyclase-activating polypeptide receptor type 1 (PAC1) performing on memory tasks
414. Contribution of dopaminergic system to the cognitive deficits induced by reduced glucocorticoid receptor function on a simultaneous visual discrimination task
415. The organization of forebrain afferents to the paraventricular and supraoptic nuclei of the rat
416. The paraventricular nucleus of hypothalamus and the functional neuroanatomy of visceromotor responses to stress
417. Down regulation of BDNF mRNA and protein in the rat hippocampus by corticosterone
418. Altered stress-induced anxiety in adenylyl cyclase type VIII deficient mice
419. 2C-adrenoceptor as a neuropsychiatric drug target. Studies in transgenic mouse models
420. Single base deletion in the vasopressin gene is the cause of diabetes insipidus in Brattleboro rats
421. Functional antagonism between oncoprotein c-jun and the glucocorticoid receptor
422. Neural regulation of the circadian rhythm in cerebrospinal fluid: A pre-eminent role for the suprachiasmatic nuclei
423. A syndrome produced by diverse nocuous agents
424. 2 receptor in the suprachiasmatic nucleus alters the circadian phenotype of mice
425. The regulation and function of c-fos and other immediate early genes in the nervous system
426. Coordinate expression of hypothalamic pro-dynorphin and pro-vasopressin mRNAs with osmotic stimulation
427. Molecular mechanism underlying activity-dependent regulation of BDNF
428. Involvement of interleukin-1 in immobilization stress-induced increase in plasma adrenocorticotropic hormone and in release of hypothalamic monoamines in the rat
429. Acute stress rapidly and persistently enhances memory formation in the male rat
430. Unpredictable and uncontrollable stress impairs neural plasticity in the rat hippocampus
431. 3H]PDBu (a marker for protein kinase C) in the amygdala, and re-exposure to the stressful context reactivates the increase
432. Effects of flesinoxan on corticosteroid receptor expression in the rat hippocampus
433. Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes
434. Enhanced morphine-induced behavioural effects and dopamine release in the nucleus accumbens in a transgenic mouse model of impaired glucocorticoid (type II) receptor function: Influence of long-term treatment with the antidepressant moclobemide
435. CREB and memory
436. Laser-capture microdissection: Opening the microscopic frontier to molecular analysis
437. Altered electrophysiology of the locus coeruleus following uncontrollable stress
438. Corticotropin-releasing factor is a potent inhibitor of sexual receptivity in the female rat
439. Chronic administration of the triazolobenzodiazepine alprazolam produces opposite effects on corticotropin-releasing factor and urocortin neuronal systems
440. CRF receptor antagonist attenuates immobilization stress-induced norepinephrine release in the prefrontal cortex in rats
441. Effects of stress and adrenalectomy on tyrosine hydroxylase mRNA levels in the locus coeruleus by in situ hybridization
442. Stress and glucocorticoids affect the expression of brain-derived neurotrophin and neurotrophin-3 mRNAs in the hippocampus
443. Effects of stress on neurotrophic factor expression in the rat brain
444. Maternal deprivation and stress induce immediate early genes in the infant rat brain
445. Corticotropin-releasing factor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development
446. The extrinsic modulation of hippocampal theta depends on the coactivation of cholinergic and GABA-ergic medial septal inputs
447. Appetitie-suppressing effects of urocortin, a CRF-related neuropeptide
448. Stress; major variable in the psychopharmacologic response
449. Dexamethasone nonsuppression in transgenic mice expressing antisense RNA to the glucocorticoid receptor
450. Corticotropin-releasing hormone receptor subtypes and emotion
451. Enhanced conditioned approach responses in transgenic mice with impaired glucocorticoid receptor function
452. Conditioned activity to amphetamine in transgenic mice expressing an antisense RNA against the glucocorticoid receptor
453. Interaction between the cholinergic system and CRH in the modulation of spatial discrimination learning in mice
454. Glucocorticoids and depression
455. Disrupted allocentric but preserved egocentric spatial learning in transgenic mice with impaired glucocorticoid receptor function
456. Glucocorticoid receptor impairment enhances impulsive responding in transgenic mice performing on a simultaneous visual discrimination task
457. Effects of the monoamine oxidase A inhibitor moclobemide on hippocampal plasticity in GR-impaired transgenic mice
458. 2 receptor antagonist, SR 48968 on the CRF-induced activation of the NE locus coeruleus-prefrontal cortex system of the rat
459. Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice
460. Overproduction of corticotropin-releasing factor in transgenic mice: A genetic model of anxiogenic behavior
461. Homozygous Brattleboro rats display attenuated conditioned freezing responses
462. Neuropeptide Y increases the corticotropin-releasing factor messenger ribonucleic acid level in the rat hypothalamus
463. Long-term effects of neonatal maternal deprivation and ACTH on hippocampal mineralocorticoid and glucocorticoid receptors
464. Differential steroid hormone and neural influences on peptide mRNA levels in CRH cells of the paraventricular nucleus: A hybridization histochemical study in the rat
465. Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: An immunohistochemical study
466. Expression of vasopressin mRNA in extrahypothalamic nuclei of the homozygous Brattleboro rat is not mediated by testosterone
467. Prenatal stress in rats: Effects on plasma corticosterone, hippocampal glucocorticoid receptors, and maze performance
468. Pituitary adenylate cyclase activating polypeptide (PACAP)-like immunoreactivity in human hypothalamus: Co-localization with arginine vasopressin
469. Quantitative trait loci associated with the behavioral response of B × D recombinant inbred mice to restraint stress: A preliminary communication
470. Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression
471. Interleukin-1-induced plasticity of hypothalamic CRH neurons and long-term stress hyperresponsiveness
472. Functional activation of CRH neurons and expression of genes encoding CRH and its receptors in food deprived lean (Fa/?) and obese (fa/fa) Zucker rats
473. Corticotropin-releasing hormone-binding proetin in brain and pituitary of food-deprived obese (fa/fa) Zucker rats
474. Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1
475. Binding of the non-peptide vasopressin V1a receptor antagonist SR-49059 in the rat brain. An in vitro and in vivo autoradiographic study
476. Disruption of glucocorticoid receptor gene in the nervous system results in reduced anxiety
477. 1A receptor agonists and benzodiazepine anxiolytics on the emotional state of naive and stressed mice: A study using the hole-board test
478. Urocortin is not a significant regulator of intermittent electro-footshock-induced adrenocorticotropin secretion in the intact male rat
479. CRF type I receptor-deficient mice exhibit a pronounced pituitary-adrenal response to local inflammation
480. Dexamethasone attenuates kainate-induced AP-1 activation in rat brain
481. Characterizaton of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and β-endorphin
482. Effects of synthetic ovine corticotropin-releasing factor, glucocorticoids, catecholamines, neurohypophyseal peptides, and other substances on cultured corticotropic cells
483. Corticotropin-releasing factor innervation of the locus coeruleus region: Distribution of fibers and sources of input
484. The locus coeruleus as a site for integrating corticotropin-releasing factor and noradrenergic mediation of stress responses
485. Reduction of stress-induced analgesia but not of exogenous opioid effects in mice lacking CB1 receptors
486. Amygdaloid corticotropin-releasing factor targets locus coeruleus dendrites: Substrate for the coordination of emotional and cognitive limbs of the stress response
487. Behavioural phenotyping of mouse mutants
488. Age effects on passive avoidance behavior in vasopressin-deficient Brattleboros
489. Early vs. late maternal deprivation differentially alters the endocrine and hypothalamic response to stress
490. Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse
491. Physiological significance of neurohypophyseal hormones in memory processes
492. Reduced synaptophysin immunoreactivity in the dentate gyrus in prepulse inhibition-impaired isolation-reared rats
493. Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor
494. The hypothalamic-pituitary-adrenal response to stress in handled and nonhandled rats: Differences in stress-induced plasma ACTH secretion are not dependent upon increased corticosterone levels
495. WAY-100635 inhibits 8-OH-DPAT-stimulated oxytocin, ACTH and corticosterone, but not prolactin secretion
496. Stress hyperalgesia in rats: An experimental animal model of anxiogenic hyperalgesia in human
497. Defeat followed by individual housing results in long-term impaired reward- and cognition-related behaviours in rats
498. Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis of the rat
499. Biochemical evidence for glutamate as a transmitter in hippocampal efferents to the basal forebrain and hypothalamus in the rat brain
500. Effects of prenatal stress on defensive withdrawal behavior and corticotropin releasing factor systems in rat brain
501. Kinetic actions and interactions of arginine vasopressin, angiotensin-II, and oxytocin on adrenocorticotropin secretion by rat anterior pituitary cells in the microperfusion system
502. Dynorphin and vasopressin: Common localization in magnocellular neurons
503. Prenatal stress selectively alters reactivity of the hypothalamic-pituitary-adrenal system in the female rat
504. Prenatal glucocorticoid programming of brain corticosteroid receptors and corticotrophin-releasing hormone: Possible implications for behaviour
505. Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH
506. CRH-deficient mice have a normal anorectic response to chronic stress
507. Urocortin expression in the Edinger-Westphal nucleus is up-regulated by stress and corticotropin-releasing hormone deficiency
508. Isolation-rearing of rats produces deficits as adults in the serotonergic innervation of hippocampus
509. 1A binding sites in 5-HT transporter knockout mice
510. Behavioral differences between vasopressin-deficient (Brattleboro) and normal Long-Evans rats
511. Altered emotionality of the vasopressin-deficient Brattleboro rat
512. Hippocampal inhibition of pituitary-adrenocortical function in female rats
513. Central oxytocin administration reduces stress-induced corticosterone release and anxiety behavior in rats
514. Infant vocalization, adult aggression, and fear behavior of an oxytocin null mutant mouse
515. Localization of urocortin messenger RNA in rat brain and pituitary
516. Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP
517. Stress-induced analgesia evoked by intraperitoneal injection of hypertonic saline: Evidence for its occurrence in vasopressin deficient rats
518. Behavioral stress facilitates the induction of long-term depression in the hippocampus
519. Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
520. Lack of tissue glucocorticoid reactivation in 11β-hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments
521. Neuroendocrine gene expression: Stress and antidepressant drugs
522. Cellular mechanisms of social attachment
523. Alpha2C adrenoceptors inhibit adenylyl cyclase in mouse striatum: Potential activation by dopamine
524. Corticosterone inhibits generation of long-term potentiation in rat hippocampal slice; involvement of brain-derived neurotrophic factor
525. 1B receptors