Genome-wide, large-scale production of mutant mice by ENU mutagenesis

Nature Genetics

Volumn 25, Issue 4, 2000, Pages 444-447

  De Angelis, Martin Hrabé ^a   Flaswinkel, Heinrich ^b   Fuchs, Helmut ^a   Rathkolb, Birgit ^c   Soewarto, Dian ^a   Marschall, Susan ^a   Heffner, Stephan ^a   Pargent, Walter ^d   Wuensch, Kurt ^a   Jung, Martin ^d   Reis, André ^e   Richter, Thomas ^a   Alessandrini, Francesca ^a   Jakob, Thilo ^a   Fuchs, Edith ^f   Kolb, Helmut ^f   Kremmer, Elisabeth ^a   Schaeble, Karlheinz ^a   Rollinski, Boris ^g   Roscher, Adelbert ^g   Peters, Christoph ^h   Meitinger, Thomas ^c   Strom, Tim ^c   Steckler, Thomas ⁱ   Holsboer, Florian ⁱ   Klopstock, Thomas ^g   Gekeler, Florian ^g   Schindewolf, Catherine ^a   Jung, Thomas ^j   Avraham, Karen ^k   Behrendt, Heidrun ^a   Ring, Johannes ^a   Zimmer, Andreas ^l   Schughart, Klaus ^m   Pfeffer, Klaus ^b   Wolf, Eckhard ^c   Balling, Rudi ^a   more..

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d Ingenium Pharmaceuticals AG   (Germany)

^e MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^f Institute of Clinical Chemistry   (Germany)

^g LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^h UNIVERSITY OF FREIBURG   (Germany)

ⁱ MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^j Institut Fuer Strahlenhygiene   (Germany)

^k TEL AVIV UNIVERSITY   (Israel)

^l NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^m TRANSGENE S A   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ETHYLNITROSOUREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL MUTAGENESIS; CONTROLLED STUDY; FEMALE; GENE FUNCTION; GENETIC SCREENING; GENOME; MALE; MEDICAL GENETICS; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CROSSES, GENETIC; CRYOPRESERVATION; ETHYLNITROSOUREA; FEMALE; FORELIMB; GENOME; IMMUNITY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MUTAGENESIS; MUTAGENS; MUTATION; PHENOTYPE;

ANIMALIA; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MELANOGASTER; RODENTIA;

EID: 0034425715     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/78146     Document Type: Article

References (13)

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10. Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2
11. Specific-locus test shows ethylnitrosourea to be the most potent mutagen in the mouse
12. Mouse ENU mutagenesis
13. Random mutagenesis screen for dominant behavioral mutations in mice