Central 5-hydroxytryptamine-2A receptor expression in transgenic mice bearing a glucocorticoid receptor antisense

Neuroendocrinology

Volumn 73, Issue 1, 2001, Pages 37-45

  Cyr, Michel ^a   Charbonneau, Chantal ^a   Morissette, Marc ^a   Rochford, Joseph ^b   Barden, Nicholas ^a   Di Paolo, Thérèse ^a  

^a LAVAL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Adrenal steroids; Cortex; Depression; Fluoxetine; Hippocampus; Molecular neuroendocrinology; Serotonin; Serotonin receptors

Indexed keywords

COMPLEMENTARY RNA; FLUOXETINE; GLUCOCORTICOID RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN UPTAKE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; HYPOTHALAMUS VENTROMEDIAL NUCLEUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEROTONINERGIC SYSTEM; TRANSGENIC MOUSE;

ANIMALS; CEREBRAL CORTEX; DEPRESSION; DNA, ANTISENSE; FEMALE; FLUOXETINE; GENE EXPRESSION; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; ORGAN CULTURE TECHNIQUES; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, GLUCOCORTICOID; RECEPTORS, SEROTONIN; RNA, MESSENGER; SEROTONIN; SEROTONIN UPTAKE INHIBITORS; SPECIES SPECIFICITY;

EID: 0035108719     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054618     Document Type: Article

References (67)

1. Regulation of 5-HT receptors by corticosteroids: Where do we stand?
2. Physiopharmacological interactions between stress hormones and central serotonergic systems
3. Corticosterone modulation of neurotransmitter receptors in rat hippocampus: A quantitative autoradiographic study
4. Adrenal steroid modulation of vasoactive intestinal peptide effect on serotonin1 binding sites in the rat brain shown by in vitro quantitative autoradiography
5. Corticosterone and serotonergic neurotransmission in the hippocampus: Functional implications of central corticosteroid receptor diversity
6. 5-Hydroxytryptamine receptors
7. Distribution of the serotonin 5-HT2 receptor family mRNAs: Comparison between 5-HT2A and 5-HT2C receptors
8. Modulation of serotonin and corticosteroid receptor gene expression in the rat hippocampus with circadian rhythm and stress
9. The effect of adrenalectomy on 5-hydroxytryptamine and corticosteroid receptor subtype messenger RNA expression in rat hippocampus
10. Different regulation of serotonin receptors following adrenal hormone imbalance in the rat hippocampus and hypothalamus
11. Differential effect of subchronic dexamethasone treatment on serotonin-2 and beta-adrenergic receptors in the rat cerebral cortex and hippocampus
12. Effect of ACTH, adrenalectomy and the combination treatment on the density of 5-HT2 receptor binding sites in neocortex of rat fore-brain and 5-HT2 receptor-mediated wet-dog shake behaviors
13. Decreased 5-HT1A and increased 5-HT2A receptor binding after chronic corticosterone associated with a behavioural indication of depression but not anxiety
14. Effects of corticosterone on 5-HT1A and 5-HT2 receptor binding and on the receptor-mediated behavioral responses of rats
15. Behavioural and biochemical evidence that glucocorticoids are not involved in DOI-elicited 5-HT2 receptor down-regulation
16. Effects of adrenalectomy and type I or type II glucocorticoid receptor activation on 5-HT1A and 5-HT2 receptor binding and 5-HT transporter mRNA expression in rat brain
17. Effect of corticosterone on serotonin and catecholamine receptors and uptake sites in rat frontal cortex
18. Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene
19. Regional serotonin metabolism under basal and restraint stress conditions in the brain of transgenic mice with impaired glucocorticoid receptor function
20. Hypothalamic-pituitary-adrenocortical axis changes in a transgenic mouse with impaired glucocorticoid receptor function
21. Behavioral and endocrine impact of impaired type II glucocorticoid receptor function in a transgenic mouse model
22. Dexamethasone nonsuppression in transgenic mice expressing antisense RNA to the glucocorticoid receptor
23. Energy balance and lipid metabolism in transgenic mice bearing an anti-sense GCR gene construct
24. Spatial memory in transgenic mice with impaired glucocorticoid receptor function
25. Behavioral reactivity to aversive stimuli in a transgenic mouse model of impaired glucocorticoid (type II) receptor function: Effects of diazepam and FG-7142
26. Dexamethasone suppression tests in antidepressant treatment of melancholia. The process of normalization and test-retest reproducibility
27. Repeated dexamethasone suppression test during depressive illness. Normalization of test result compared with clinical improvement
28. Antidepressant drug action in a transgenic mouse model of the endocrine changes seen in depression
29. Central 5-HT(1) and 5-HT(2) binding sites in transgenic mice with reduced glucocorticoid receptor number
30. Immunohistochemical localization of the 5-HT2C receptor protein in the rat CNS
31. Localization of the 5-hydroxy-tryptamine2C receptor protein in human and rat brain using specific antisera
32. 3H]MDL 100,907
33. 18F]setoperone PET imaging study
34. 18F]-setoperone during depressive illness and antidepressant treatment with clomipramine
35. Serotonin receptors in suicide victims with major depression
36. 5HT2 receptors, depression and anxiety
37. Regulation of central corticosteroid receptors following short-term activation of serotonin transmission by 5-hydroxy-L-tryptophan or fluoxetine
38. The antidepressants fluoxetine, idazoxan and phenelzine alter corticotropin-releasing hormone and tyrosine hydroxylase mRNA levels in rat brain: Therapeutic implications
39. Antidepresssants preferentially enhance habituation to novelty in the olfactory bulbectomized rat
40. Differential modulation of anti-predator defensive behavior in Swiss-Webster mice following acute or chronic administration of imipramine and fluoxetine
41. Structure and functional expression of cloned rat serotonin 5HT-2 receptor
42. Gene structure and expression of the mouse 5-HT2 receptor
43. Gonadal hormones modulate 5-hydroxytryptamine2A receptors: Emphasis on the rat frontal cortex
44. Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system?
45. Anatomical resolution of two types of corticosterone receptor sites in rat brain with in vitro autoradiography and computerized image analysis
46. Binding characteristics of mineralocorticoid and glucocorticoid receptors in dog brain and pituitary
47. Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat
48. Distribution of the mineralocorticoid and the glucocorticoid receptor mRNAs in the rat hippocampus
49. Co-localization of alpha1D adrenergic receptor mRNA with mineralocorticoid and glucocorticoid receptor mRNA in rat hippocampus
50. Regulation of adrenocorticosteroid receptor mRNA expression in the central nervous system
51. Glucocorticoid receptor impairment alters CNS responses to a psychological stressor: An in vivo microdialysis study in transgenic mice
52. Cloning and functional promoter mapping of the rat serotonin-2 receptor gene
53. Molecular mechanisms of anti-inflammatory action of glucocorticoids
54. Transcriptional cross-talk, the second mode of steroid hormone receptor action
55. Regulation of the rat serotonin-1A receptor gene by corticosteroids
56. Transcriptional control of the rat serotonin-2 receptor gene
57. 125I]DOI-labeled 5-HT2A/2C receptors in the hypothalamus without changing the levels of Gq- and G11-proteins
58. Effects of repeated treatment with fluoxetine and citalopram, 5-HT uptake inhibitors, on 5-HT1A and 5-HT2 receptors in the rat brain
59. Effects of repeated fluoxetine on anxiety-related behaviours, central serotonergic systems, and the corticotropic axis in SHR and WKY rats
60. Frontal 5-HT2A receptors studied in depressive patients during chronic treatment by selective serotonin reuptake inhibitors
61. Chronic administration of the antidepressants phenelzine, desipramine, clomipramine, or maprotiline decreases binding to 5-hydroxytryptamine2A receptors without affecting benzodiazepine binding sites in rat brain
62. Identification of an inducible form of cytochrome P-450 in human liver
63. Demonstration in multiple species of inducible hepatic cytochromes P-450 and their mRNAs related to the glucocorticoid-inducible cytochrome P-450 of the rat
64. The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver