Spatial learning deficits in mice with a targeted glucocorticoid receptor gene disruption

European Journal of Neuroscience

Volumn 9, Issue 11, 1997, Pages 2284-2296

  Oitzl, Melly S ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Behavioural reactivity; Impairment of hippocampal function; Mineralocorticoid receptor; Water maze

Indexed keywords

BRAIN RECEPTOR; GLUCOCORTICOID RECEPTOR; MINERALOCORTICOID RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; GENE DISRUPTION; GENE TARGETING; HETEROZYGOSITY; HIPPOCAMPUS; HOMOZYGOSITY; INFORMATION PROCESSING; LEARNING DISORDER; MALE; MAZE TEST; MEMORY; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPATIAL DISCRIMINATION; SPATIAL MEMORY; VISUAL INFORMATION;

ANIMALS; CUES; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MOTOR ACTIVITY; RECEPTORS, GLUCOCORTICOID;

EID: 0031437277     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01646.x     Document Type: Article

References (2)

1. Barden, N., Reul, J. M. H. M. and Holsboer, F. (1995) Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenal system? Trends Neurosci., 18, 6-11.
2. Bodnoff, S. R., Humphreyz, A. G., Lehman, J. C., Diamond, D. M., Rose, G. M. and Meaney, M. J. (1995) Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats. J. Neurosci., 15, 61-69.