Central 5-HT1 and 5-HT2 binding sites in transgenic mice with reduced glucocorticoid receptor number

Brain Research

Volumn 862, Issue 1-2, 2000, Pages 145-153

  Farisse, Jean ^a   Héry, Francis ^a   Barden, Nicholas ^b   Héry, Micheline ^a   Boulenguez, Pascale ^a  

^a INSERM   (France)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

5 HT(1A); 5 HT(1B); 5 HT2; GR; MR; Transgenic mice

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; GLUCOCORTICOID RECEPTOR; MESULERGINE; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN 2 RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; BRAIN REGION; CHOROID PLEXUS; CONTROLLED STUDY; DEPRESSION; DORSAL RAPHE NUCLEUS; HIPPOCAMPUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SEROTONINERGIC TRANSMISSION; TRANSGENIC MOUSE;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; AMYGDALA; ANIMALS; AUTORADIOGRAPHY; BINDING SITES; BRAIN CHEMISTRY; CORPUS STRIATUM; DOWN-REGULATION; HIPPOCAMPUS; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PREFRONTAL CORTEX; RAPHE NUCLEI; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTORS, GLUCOCORTICOID; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; RNA, MESSENGER; SEROTONIN AGONISTS; TRITIUM; UP-REGULATION;

EID: 0342804290     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02104-1     Document Type: Article

References (60)

1. 1C receptors in rat brain. J. Pharmacol. Exp. Ther. 255:1990;843-857.
2. 3H-serotonin in brain areas of adrenalectomized rats. Science. 169:1970;201-203.
3. Azmitia E.C., Mc Ewen B.S. Adrenalcortical influence on rat brain tryptophan hydroxylase activity. Brain Res. 78:1974;291-302.
4. Azmitia E.C., Liao B., Chen Y.S. Increase of tryptophan hydroxylase enzyme protein by dexamethasone in adrenalectomized rat midbrain. J. Neurosci. 13:1993;5041-5055.
5. 1 agonists in the rat. Neuroendocrinology. 50:1989;241-247.
6. 1B receptors in the rat brain. Eur. J. Pharmacol. 294:1995;531-540.
7. 1B receptor is localized predominantly on axon terminals. Neuroscience. 58:1994;167-182.
8. 1A/1C binding sites revealed by quantitative receptor autoradiography. Neuroscience. 53:1993;465-473.
9. 1A binding in the rat brain - a combined in situ hybridisation/in vitro receptor autoradiographic study. Brain Res. 561:1991;51-60.
10. 1A receptor mRNA expression. J. Neurosci. 13:1993;914-923.
11. 1A receptor gene expression by dexamethasone. Neuropsychopharmacology. 10:1994;215-222.
12. Chaouloff F. Physiopharmacological interactions between stress hormones and central serotonergic systems. Brain Res. Rev. 18:1993;1-32.
13. Chaouloff F., Baudrie V., Coupry I. Behavioural and biochemical evidence that glucocorticoids are not involved in DOI-elicited 5-HT2 receptor down-regulation. Eur. J. Pharmacol. 249:1993;117-120.
14. Chaouloff F. Regulation of 5-HT receptors by corticosteroids: where do we stand? Fundam. Clin. Pharmacol. 9:1995;219-233.
15. 3H]ketanserin binding and 5-HT2A receptor-mediated behavioral responses in obese Zucker rats. Pharmacol. Biochem. Behav. 50:1995;309-312.
16. De Kloet E.R. Brain corticosteroid receptor balance and homeostatic control. Front. Neuroendocrinol. 12:1991;95-164.
17. De Kloet E.R., Kovacs G.L., Szabo G., Telegdy G., Bohus B., Versteeg D.H. Decreased serotonin turnover in the dorsal hippocampus of rat brain shortly after adrenalectomy: selective normalization after corticosterone substitution. Brain Res. 239:1982;659-663.
18. De Montigny C., Chaput Y., Blier P. Classical and novel targets for antidepressant drugs. Mendlewicz J., Brunello N., Langer S.Z., Racagni G. New Pharmacological Approaches to the Therapy of Depressive Disorders. International Academy of Biomedical Drug Research. Vol. 5:1993;8-17 Karger, Basel.
19. Dinan T.G. Glucocorticoids and the genesis of depressive illness. A psychobiological model. Br. J. Psychiatry. 164:1994;365-371.
20. J. Farisse, P. Boulenguez, A. Sémont, F. Héry, N. Barden, M. Faudon, M. Héry, Regional serotonin metabolism under basal and restraint stress conditions in the brain of transgenic mice with impaired glucocorticoid receptor function, Neuroendocrinology, 2000 (in press).
21. Franklin K.R.J., Paxinos G.G. The Mouse Brain in Stereotaxic Coordinates. 1996;Academic Press, New York.
22. Holmes M.C., Yau J.L.W., French K.L., Seckl J.R. The effect of adrenalectomy on 5-hydroxytryptamine and corticosteroid receptor subtype messenger RNA expression in rat hippocampus. Neuroscience. 64:1995;327-337.
23. Holsboer F., Barden N. Antidepressants and hypothalamic-pituitary-adrenocortical regulation. Endocr. Rev. 17:1996;187-205.
24. 2 sites in cortex and amygdala. Brain Res. 614:1993;37-44.
25. 1A receptor mRNA in adult rat hippocampal dentate gyrus. Neurosci. Lett. 270:1999;5-8.
26. 1 neurons. J. Neurosci. 11:1991;2288-2294.
27. Korte-Bouws G.A., Korte S.M., de Kloet E.R., Bohus B. Blockade of corticosterone synthesis reduces serotonin turnover in the dorsal hippocampus of the rat as measured by microdialysis. J. Neuroendocrinol. 8:1996;877-881.
28. Kuroda Y., Mikuni M., Nomura N., Takahashi K. Differential effect of subchronic dexamethasone treatment on serotonin-2 and b-adrenergic receptors in the rat cerebral cortex and hippocampus. Neurosci. Lett. 155:1993;195-198.
29. 2 receptor-mediated wet-dog shake behaviors. Psychopharmacology. 108:1992;27-32.
30. Kuroda Y., Watanabe Y., Albeck D.S., Hastings N.B., McEwen B.S. Effects of adrenalectomy on type I and II glucocorticoid receptor activation on 5-HT1A and 5-HT2 receptor binding and 5-HT transporter mRNA expression in rat brain. Brain Res. 648:1994;157-161.
31. 1A autoreceptor functioning in the rat dorsal raphe nucleus. Neuropharmacology. 34:1995;1201-1210.
32. 1A receptor mRNA in the dentate gyrus of the long-term adrenalectomized rats and rapid reversal by dexamethasone. Mol. Brain Res. 19:1993;328-332.
33. 1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: implications for the neurobiology of depression. Biol. Psychiatry. 43:1998;547-573.
34. 1A receptor messenger RNA regulation in the hippocampus after acute stress. Biol. Psychiatry. 45:1999;934-937.
35. Maes M., Melzer H.Y. The serotonin hypothesis of major depression. Bloom F.E., Kupfer D.J. Psychopharmacology: The Fourth Generation of Progress. 1995;933-944 Raven Press, New York. Chapter 81.
36. Martire M., Pistritto G., Preziosi P. Different regulation of serotonin receptors following adrenal hormone imbalance in the rat hippocampus and hypothalamus. J. Neural Transm. 78:1989;109-120.
37. 125I]DOI, a new psychomimetic radioligand. Brain Res. 476:1989;45-56.
38. McKittrick C.R., Blanchard D.C., Blanchard R.J., McEwen B.S., Sakai R.R. Serotonin receptor binding in a colony model of chronic social stress. Biol. Psychiatry. 37:1995;383-393.
39. Meijer O.C., De Kloet E.R. Corticosterone and serotonergic neurotransmission in the hippocampus: functional implications of central corticosteroid receptor diversity. Crit. Rev. Neurobiol. 12:1998;1-20.
40. 1A receptor mRNA and binding in transgenic mice with a targeted disruption of the glucocorticoid receptor. Mol. Brain Res. 46:1997;290-296.
41. 2 receptors in the dorsal hippocampus of male and female rats. Neuroendocrinology. 54:1991;454-461.
42. 1A receptors in rat forebrain. Neuroendocrinology. 56:1992;881-888.
43. 1B receptors in the dorsal hippocampus and cortex of the rat. Neuroendocrinology. 55:1992;444-450.
44. 1A receptors: respective distributions of encoding mRNA, receptor protein and binding sites by in situ hybridization histochemistry, radioimmunohistochemistry and autoradiographic mapping in the rat brain. Neurochem. Int. 19:1991;453-465.
45. 2+ mobilization in C6 glioma cells. Neuroendocrinology. 57:1993;322-329.
46. 1A receptor in hippocampal cell culture. Synapse. 31:1999;186-195.
47. Pazos A., Cortés R., Palacios J.M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors. Brain Res. 346:1985;231-249.
48. Pepin M.C., Pothier F., Barden N. Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene. Nature. 355:1992;725-728.
49. 1A receptor system in rat brain. Neuroendocrinology. 65:1997;246-258.
50. Salomon R.M., Miller H.L., Delgado P.L., Charney D. The use of tryptophan depletion to evaluate central serotonin function in depression and other neuropsychiatric disorders. Int. Clin. Pharmacol. 8:1993;41-46.
51. 1A receptor mRNA in the dentate gyrus independently of high plasma corticosterone levels. Eur. J. Pharmacol. 353:1998;207-214.
52. Singh V.B., Corley K.C., Phan T.H., Boadle-Biber M.C. Increases in the activity of tryptophan hydroxylase from rat cortex and midbrain in response to acute or repeated sound stress are blocked by adrenalectomy and restored by dexamethasone treatment. Brain Res. 516:1990;66-76.
53. Singh V.B., Phan T.H., Corley K.C., Boadle-Biber M.C. Increase in cortical and midbrain tryptophan hydroxylase activity by intracerebroventricular administration of corticotropin releasing factor: block by adrenalectomy, by RU 38486, and by bilateral lesions to the central nucleus of the amygdala. Neurochem. Int. 20:1992;81-92.
54. Todd K.G., McManus D.J., Baker G.B. Chronic administration of the antidepressants phenelzine, desipramine, clomipramine, or maprotiline decreases binding to 5-hydroxytryptamine2A receptors without affecting benzodiazepine binding sites in rat brain. Cell. Mol. Neurobiol. 15:1995;361-370.
55. Van Eekelen J.A., De Kloet E.R. Co-localization of brain corticosteroid receptors in the rat hippocampus. Prog. Histochem. Cytochem. 26:1992;250-258.
56. Van Loon G.R., Shum A., Sole M.J. Decreased brain serotonin turnover after short term (two-hour) adrenalectomy in rats: a comparison of four turnover methods. Endocrinology. 108:1981;1392-1401.
57. 1 receptor subtypes in the brain of control or 5,7-dihydroxytryptamine-treated rats. J. Neurosci. 6:1986;3474-3482.
58. 2 receptors and transport sites for serotonin. Brain Res. 615:1993;87-94.
59. Young A.H., MacDonald L.M., St John H., Dick H., Goodwin G.M. The effects of corticosterone on 5-HT receptor function in rodents. Neuropharmacology. 31:1992;433-438.
60. 1A receptors by corticosteroid hormones. Mol. Brain Res. 29:1995;23-34.