Sequence of stress-induced alterations in indices of synaptic and transcriptional activation in parvocellular neurosecretory neurons

Journal of Neuroscience

Volumn 16, Issue 1, 1996, Pages 262-273

  Kovacs K J ^a,b   Sawchenko, P E ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

arginine vasopressin; c fos; cAMP; corticotropin releasing factor; hypothalamo pituitary adrenal axis; neurosecretory neurons; stress

Indexed keywords

ARGIPRESSIN; CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ETHER; HETEROGENEOUS NUCLEAR RNA; MESSENGER RNA; NERVE GROWTH FACTOR; ONCOPROTEIN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HORMONE RELEASE; IMMEDIATE EARLY GENE; MALE; NEUROSECRETORY CELL; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; STRESS; SYNAPTIC TRANSMISSION; TRANSCRIPTION REGULATION;

EID: 0030070524     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-01-00262.1996     Document Type: Article

References (68)

1. Abercrombie M (1946) Estimation of nuclear population from microtome sections. Anat Rec 94:239-247.
2. Antoni FA (1986) Hypothalamic control of adrenocorticotropin secretion: advances since the discovery of 41-residue corticotropin-releasing factor. Endocrine Rev 7:351-378.
3. Antoni FA, Fink G, Sheward WJ (1990) Corticotropin-releasing peptides in rat hypophyseal portal blood after paraventricular lesions: a marked reduction in the concentration of corticotrophin-releasing factor-1, but no change in vasopressin. J Endocrinol 125:175-183.
4. Armstrong RC, Montminy MM (1993) Transsynaptic control of gene expression. Annu Rev Neurosci 16:17-29.
5. Borsook D, Konradi C, Falkowski O, Comb M, Hyman SE (1994) Molecular mechanisms of stress-induced proenkephalin gene regulation: CREB interacts with the proenkephalin gene in the mouse hypothalamus and is phosphorylated in response to hyperosmolar stress. Mol Endocrinol 8:240-248.
6. Bruhn TO, Plotsky PM, Vale WW (1984) Effect of paraventricular lesions on corticotropin-releasing factor (CRF)-like immunoreactivity in stalk-median eminence: studies on the adrenocorticotropin response to ether stress and exogenous CRF. Endocrinology 114:57-62.
7. Buma P, Nieuwenhuys R (1987) Ultrastructural demonstration of oxytocin and vasopressin release sites in the neural lobe and median eminence of the rat by tannic acid and immunogold methods. Neurosci Lett 74:151-157.
8. Ceccatelli S, Villar MJ, Goldstein M, Hökfelt T (1989) Expression of c-fos immunoreactivity in transmitter-characterized neurons after stress Proc Natl Acad Sci USA 86:9569-9573.
9. Chan RKW, Brown ER, Ericsson A, Kovács KJ, Sawchenko PE (1993) A comparison of two immediate-early genes, c-fos and NGFI-B, as markers for functional activation in stress-related neuroendocrine circuitry. J Neurosci 13:5126-5138.
10. DeGoeij DC, Kvetnansky R, Whitnall MH, Jezova D, Berkenbosch F, Tilders FJ (1991) Repeated stress-induced activation of corticotropin-releasing factor neurons enhances vasopressin stores and colocalization with corticotropin-releasing factor in the median eminence of rats. Neuroendocrinology 53:150-159.
11. Ding JM, Carver WC, Terracio L, Buggy J (1994) Proto-oncogene c-fos and the regulation of vasopressin gene expression during dehydration Mol Brain Res 21:247-255.
12. Dorin RI, Zlock DW, Kilpatrick K (1993) Transcriptional regulation of human corticotropin releasing factor gene expression by cyclic 3′,5′-monophosphate: differential effects at proximal and distal promoter elements. Mol Cell Endocrinol 96:99-111.
13. Ericsson A, Kovács KJ, Sawchenko PE (1994) A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons. J Neurosci 14:897-913.
14. Ginty DD, Bonni A, Greenberg ME (1994) Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell 77:713-725.
15. Ginty DD, Kornhauser JM, Thompson MA, Bading H, Mayo KE, Takahashi JS, Greenberg ME (1993) Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science 260:238-241.
16. Gonzalez GA, Montminy MR (1989) Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675-680.
17. Guardiola-Diaz HM, Boswell C, Seasholtz AF (1994) The cAMP-responsive element in the corticotropin-releasing hormone gene mediates transcriptional regulation by depolarization. J Biol Chem 269:14784-14791.
18. Hagiwara M, Brindle P, Harootunian A, Armstrong R, Rivier J, Vale W, Tsien R, Montminy MR (1993) Coupling of hormonal stimulation and transcription via the cyclic AMP-responsive factor CREB is rate limited by nuclear entry of protein kinase A. Mol Cell Biol 13:4852-4859.
19. Harbuz MS, Lightman SL (1992) Stress and the hypothalamo-pituitary-adrenal axis: acute, chronic and immunological activation. J Endocrinol 134:327-339.
20. He X, Treacy M, Simmons D, Ingraham H, Swanson LW. Rosenfeld M (1989) Expression of a large family of POU-domain regulatory genes in mammalian development. Nature 340:35-42.
21. Herman JP (1995) In situ hybridization analysis of vasopressin gene transcription in the paraventricular and supraoptic nuclei of the rat: regulation by stress and glucocorticoids. J Comp Neurol, in press.
22. Herman JP, Schafer MK-H, Sladek CD, Day R, Young EA, Akil H (1989) Chronic electroconvulsive shock treatment elicits up-regulation of CRF and AVP in select populations of neuroendocrine cells. Brain Res 501:235-246.
23. Herman JP, Schafer M, Thompson RC, Watson SJ (1992) Rapid regulation of corticotropin-releasing hormone gene transcription in vivo Mol Endocrinol 6:1061-1069.
24. Herman JP, Schafer MK-H, Watson SJ, Sherman TG (1991) In situ hybridization analysis of argimne vasopressin gene transcription using intron-specific probes. Mol Endocrinol 5:1447-1456.
25. Hoffman GE, Verbalis JG, Smith MS (1993) c-Fos and related immediate early gene products as markers of activity in neuroendocrine systems. Front Neuroendocrinol 14:173-213.
26. Holmes MC, Antoni FA, Aguilera G, Catt KJ (1986) Magnocellular axons in passage through the median eminence release vasopressin. Nature 319:326-329.
27. Imaki T, Shibasaki T, Hotta M, Demura D (1992) Early induction of c-fos precedes increased expression of corticotropin-releasing factor messenger ribonucleic acid in the paraventricular nucleus after immobilization stress. Endocrinology 131:240-246.
28. Kiss JZ, Mezey E, Skirboll L (1984) Corticotropin-releasing factor-immunoreactive neurons of the paraventricular nucleus become vasopressin positive after adrenalectomy. Proc Natl Acad Ssi USA 81:1854-1858.
29. Konradi C, Cole RL, Heckers S, Hyman SE (1994) Amphetamine regulates gene expression in rat striatum via transcription factor CREB. J Neurosci 14:5623-5634.
30. Kovács KJ, Makara GB (1988) Corticosterone and dexamethasone act at different brain sites to inhibit adrenalectomy-induced adrenocorticotropin hypersecretion. Brain Res 474:205-210.
31. Kovács KJ, Makara GB (1990) Partial deafferentation of the hypothalamic paraventricular nucleus: effect on the stress- or adrenalectomy-induced ACTH secretion. Neuroendocrinol Lett 12:383-389.
32. Kovács KJ, Sawchenko PE (1994) Stress-induced transcriptional activation of the corticotropin-releasing factor gene precedes immediate-early genes responses in the paraventricular nucleus. Soc Neurosci Abstr 20:935.
33. Lalli E, Sassone-Corsi P (1994) Signal transduction and gene regulation: the nuclear response to cAMP. J Biol Chem 269:17359-17362.
34. Li P, He X, Gerrero MR, Mok M, Aggarwal A, Rosenfeld MG (1993) Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants from POU domain factors. Genes Dev 7:2483-2496.
35. Lightman SL, Young III WS (1988) Corticotropin-releasing factor, vasopressin and proopiomelanocortin mRNA responses to stress and opiates in the rat. J Physiol (Lond) 403:511-523.
36. Majzoub JL, Emmanuel R, Adler G, Martinez C, Robinson B, Wittert G (1993) Second messenger regulation of mRNA for corticotropin-releasing factor. The Netherlands: Ciba Foundation Symposium 172, pp 30-43.
37. Morgan JI, Curran T (1991) Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annu Rev Neurosci 14:421-451.
38. Pardy K, Adan RAH, Carter DA, Seah V, Burbach JPH, Murphy D (1992) The identification of a cis-acting element involved in cyclic 3′,5′-adenosine monophosphate regulation of bovine vasopressin gene expression. J Biol Chem 267:21746-21752.
39. Plotsky PM (1991) Pathways to the secretion of adrenocorticotropin: a view from the portal. J Neuroendocrinol 3:1-9.
40. Priou A, Oliver C, Grino M (1993) In situ hybridization of arginme vasopressin (AVP) heteronuclear ribonucleic acid reveals increased AVP gene transcription in the rat hypothalamic paraventricular nucleus in response to emotional stress. Acta Endocrinol 128:466-472.
41. Rivier C, Rivier J, Vale W (1982) Inhibition of adrenocorticotropic hormone secretion in rat by immunoneutralization of corticotropin-releasing factor (CRF). Science 218:377-379.
42. Rivier C, Vale W (1983) Interaction of corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin secretion in vivo. Endocrinology 113:939-942.
43. Rivier C, Vale W, Guillemin R (1973) An in vivo corticotropin-releasing factor (CRF) assay based on plasma levels of radioimmunoassayable ACTH. Proc Soc Exp Biol Med 142:842-845.
44. Sassone-Corsi P, Visvader J, Ferland L, Mellon PL, Verma IM (1988) Induction of proto-oncogene fos transcription through the adenylate-cyclase pathway: characterization of a cAMP-responsive element. Genes Dev 2:1529-1538.
45. Sawchenko PE, Arias CA, Mortrud M (1993a) Evidence for synaptic mediation of chronic stress effects on corticotropin-releasing factor and vasopressin mRNAs in hypophysiotropic neurons. J Neuroendocrinol 5:341-348.
46. Sawchenko PE, Cunningham Jr ET, Mortrud MT, Pfeiffer SW, Gerfen CR (1990) Phaseolus vulgaris-leucoagglutinin anterograde axonal transport technique. In: Methods in neurosciences, Vol 3 (Conn PM, ed), pp 247-260. New York: Academic.
47. Sawchenko PE, Imaki T, Potter E, Kovács KJ, Vale W (1993b) The functional neuroanatomy of corticotropin-releasing factor. In: Corticotropin-releasing factor, Ciba Foundation Symposium 172 (Chadwick DJ, Marsh J, Ackrill K, eds), pp 5-29. Chichester: Wiley.
48. Sawchenko PE, Swanson LW (1982) The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat. J Comp Neurol 205:260-272.
49. Sawchenko PE, Swanson LW, Vale WW (1984) Co-expression of corticotropin-releasing factor and vasopressin immunoreactivity in parvocellular neurosecretoiy neurons of the adrenalectomized rat. Proc Natl Acad Sci USA 81:1883-18876.
50. Schoenemann MD, Ryan AK, McEvilly RJ, O'Connell SM, Arias CA, Kalla K, Li P, Sawchenko PE, Rosenfeld MG (1995) Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. Genes Dev, in press.
51. Schule R, Rangarajan P, Kliewer S, Ransone LJ, Bolado J, Yang N, Verma IM, Evans RM (1990) Functional antagonism between oncoprotein c-jun and the glucocorticoid receptor. Cell 62:1217-1226.
52. Seasholtz AF, Thompson RC, Douglass JO (1988) Identification of a cyclic adenosine monophosphate-responsive element in the rat corticotropin-releasing hormone gene. Mol Endocrinol 2:1311-1319.
53. Sheng M, McFadden G, Greenberg ME (1990) Membrane depolarization and calcium induce c-fos via phosphorylation of transcription factor CREB. Neuron 4:571-582.
54. Simmons DM, Arriza JL, Swanson LW (1989) A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabeled single-stranded RNA probes. J Histotechnol 12:169-181.
55. Stauber C, Altschmeid J, Akerblom IE, Marron JL, Mellon PL (1990) Mutual cross-interference between glucocorticoid receptor and CREB inhibits transactivation in placental cells. New Biol 4:527-540.
56. Swanson LW, Kuypers HGJM (1980) The paraventricular nucleus of the hypothalamus: cytoarchitectonic subdivisions and the organization of projections to the pituitary, dorsal vagal complex and spinal cord as demonstrated by retrograde fluorescence double labeling methods. J Comp Neurol 194:555-570.
57. Swanson LW, Simmons DM (1989) Differential steroid hormone and neural influences on peptide mRNA levels in CRH cells of the paraventricular nucleus: a hybridization histochemical study in the rat. J Comp Neurol 285:413-435.
58. Uht RM, McKelvy JF, Harrison RW, Bohn M (1988) Demonstration of giucorticoid receptor-like immunoreactivity in glucocorticoid-sensitive vasopressin and corticotropin-releasing factor neurons in the hypothalamic paraventricular nucleus. J Neurosci Res 19:405-411.
59. Verbeeck MAE, Adan RAH, Burbach JPH (1990) Vasopressin gene expression is stimulated by cyclic AMP in homologous and heterologous expression systems. FEBS Lett 272:89-93.
60. Vallejo M (1994) Transcriptional control of gene expression by cAMP-response element binding proteins. J Neuroendocrinol 6:587-596.
61. Watts AG (1991) Ether anesthesia differentially affects the content of prepro-corticotropin-releasing hormone, prepro-neurotensin/neuromedin N and prepro-enkephalin mRNAs in the hypothalamic paraventricular nucleus of the rat. Brain Res 544:353-357.
62. Watts AG, Swanson LW (1989) The combination of in situ hybridization with immunohistochermstry and retrograde tract-tracing. In: Methods in neurosciences (Conn PM, ed), pp 127-136. New York: Academic.
63. Wenger M, Drolet DW, Rosenfeld MG (1993) POU-domain proteins: structure and function of developmental regulators. Curr Opin Cell Biol 5:488-498.
64. Whitnall MH (1993) Regulation of the hypothalamic corticotropin-releasing hormone neurosecretory system. Prog Neurobiol 40:573-629.
65. Whitnall MH, Mezey E, Gainer H (1985) Co-localization of corticotropin-releasing factor and vasopressin in median eminence neurosecretory vesicles. Nature 317:248-250.
66. Whitnall MH, Smythe D, Gainer H (1987) Vasopressin coexists in half the corticotropin-releasing factor axons present in the external zone of the median eminence in normal rats. Neuroendocnnology 45:420-424.
67. Yang-Yen HF, Chambard JC, Sun YL, Smeal T, Schmidt TJ, Drouin J, Karin M (1990) Transcriptional interference between c-jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62:1205-1215.
68. Young III WS, Mezey E, Siegel RE (1986) Vasopressin and oxytocin mRNAs in adrenalectomized and Brattleboro rats: analysis by quantitative in situ hybridization histochemistry. Mol Brain Res 1:231-241.