Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 4, 2001, Pages 1912-1917

  Santarelli, Luca ^a   Gobbi, Gabriella ^b   Debs, Pierre C ^a,c   Sibille, Etienne L ^a   Blier, Pierre ^b   Hen, René ^a   Heath, Mark J S ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; NEUROKININ 1 RECEPTOR; NEUROPEPTIDE; NEUROTRANSMITTER; NORADRENALIN; SEROTONIN; SEROTONIN 1A ANTAGONIST; SUBSTANCE P;

AFFECTIVE NEUROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY NEUROSIS; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DEPRESSION; DESENSITIZATION; DORSAL RAPHE NUCLEUS; EMOTION; GENE DELETION; GENE DISRUPTION; GENE TARGETING; MALE; MOUSE; NERVE CELL; NEUROTRANSMISSION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; STRESS;

ANIMALIA;

EID: 0035852719     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.98.4.1912     Document Type: Article

References (39)