Effect of novel stressors on gene expression of tyrosine hydroxylase and monoamine transporters in brainstem noradrenergic neurons of long-term repeatedly immobilized rats

Brain Research

Volumn 899, Issue 1-2, 2001, Pages 20-35

  Rusnák, Milan ^a,b   Kvetanský, Richard ^a   Jeloková, Jana ^a   Palkovits, Miklós ^c  

^a INSTITUTE OF EXPERIMENTAL ENDOCRINOLOGY   (Slovakia)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Brainstem noradrenergic cell group; Gene expression; Locus coeruleus; Norepinephrine transporter; Novel stressor; Repeated stress; Tyrosine hydroxylase; Vesicular monoamine transporter

Indexed keywords

DEOXYGLUCOSE; INSULIN; MESSENGER RNA; NORADRENALIN TRANSPORTER; TYROSINE 3 MONOOXYGENASE; VESICULAR ACETYLCHOLINE TRANSPORTER;

ANIMAL EXPERIMENT; ARTICLE; BRAIN STEM; COLD EXPOSURE; CONTROLLED STUDY; GENE EXPRESSION; HISTOCHEMISTRY; HYPOGLYCEMIA; IMMOBILIZATION STRESS; IN SITU HYBRIDIZATION; LOCUS CERULEUS; MALE; NERVE POTENTIAL; NONHUMAN; NORADRENERGIC NERVE; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN STEM; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IMMOBILIZATION; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NEURONS; NEUROPEPTIDES; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STRESS; SYMPORTERS; TIME; TYROSINE 3-MONOOXYGENASE; VESICULAR BIOGENIC AMINE TRANSPORT PROTEINS; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 0035957794     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02126-6     Document Type: Article

References (79)

1. Single-unit response of noradrenergic neurons in the locus coeruleus of freely moving cats. I. Acutely presented stressful and nonstressful stimuli
2. Chronic stress increases serotonin and noradrenaline in rat brain and sensitizes their response to further acute stress
3. Neurotransmitter transporters: Recent progress
4. Different stressors have different effects on c-fos activity of catecholaminergic neurons
5. REM sleep deprivation increases the levels of tyrosine hydroxylase and norepinephrine transporter mRNA in the locus coeruleus
6. Regulation of norepinephrine transporter and tyrosine hydroxylase mRNAs after kainic acid-induced seizures
7. Selective activation of postsynaptic 5-HT1A receptors induces rapid antidepressant response
8. Catecholamine reuptake and storage
9. Spatial and temporal expresssion of alpha- and beta-thyroid hormone receptor mRNAs, including the beta 2-subtype, in the developing mammalian nervous system
10. Repeated electroconvulsive shock produces long-lasting increases in messenger RNA expression of corticotropin-releasing hormone and tyrosine hydroxylase in rat brain
11. Neuroanatomical basis for facilitation of hypothalamo-pituitary-adrenal responses to a novel stressor after chronic stress
12. Noradrenergic mechanisms in stress and anxiety. I: Preclinical studies
13. Uptake of nucleotides and catecholamines by chromaffin granules from pig and horse adrenal medulla
14. Regional changes in c-fos expression in the basal forebrain and brainstem during adaptation to repeated stress: Correlations with cardiovascular, hypothermic and endocrine responses
15. Induction and adaptation of Fos expression in the rat brain by two types of acute restraint stress
16. Noradrenaline transporter expression in the pons and medulla oblongata of the rat: Localization to noradrenergic and some C1 adrenergic neurones
17. Differential in vivo regulation of mRNA encoding the norepinephrine transporter and tyrosine hydroxylase in rat adrenal medulla and locus coeruleus
18. Organization of the adrenergic inputs to the paraventricular and supraoptic nuclei of the hypothalamus in the rat
19. Adaptation to prolonged or repeated stress - Comparison between rat strains showing intrinsic difference in reactivity to acute stress
20. Insulin reduces norepinephrine transporter mRNA in vivo in rat locus coeruleus
21. The involvement of noradrenergic ascending pathways in the stress-induced activation of ACTH and corticosterone secretions is dependent on the nature of stressors
22. Effects of 6-hydroxydopamine-induced lesions of the paraventricular nucleus, and of prazosin, on the corticosterone response to restraint in rats
23. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
24. Regional rat brain noradrenaline turnover in response to restraint stress
25. CO2-induced c-fos expression in the CNS catecholaminergic neurons
26. The effect of acute, chronic and chronic intermittent stress on the central noradrenergic system
27. Distribution of monoamine neurotransmitter transporters in the rat brain
28. The dopamine transporter: A crucial component regulating dopamine transmission
29. Reserpine as a competitive and reversible inhibitor of the catecholamine transporter of bovine chromaffin granules
30. Sensitization of sympathetic-adrenal medullary responses to a novel stressor in chronically stressed laboratory rats
31. Adrenal and urinary catecholamines in rats during adaptation to repeated immobilization stress
32. Catecholamines in individual hypothalamic nuclei of acutely and repeatedly stressed rats
33. Plasma catecholamines in rats during adaptation to intermittent exposure to different stressors
34. Endogenous glucocorticoids restrain catecholamine synthesis and release at rest and during immobilization stress in rats
35. Novel stressors exaggerate the tyrosine hydroxylase gene expression in the adrenal medulla of rats exposed to long-term cold stress
36. Differential early time course activation of the brainstem catecholaminergic groups in response to various stresses
37. The habituation of brainstem catecholaminergic groups to chronic daily restraint stress is stress specific like that of the hypothalamo-pituitary-adrenal axis
38. Short- and long-term alterations of gene expression in limbic structures by repeated electroconvulsive-induced seizures
39. Distinct mechanisms underlie activation of hypothalamic neurosecretory neurons and their medullary catecholaminergic afferents in categorically different stress paradigms
40. Hypothalamic effector neurons and extended circuitries activated in "neurogenic" stress: A comparison of footshock effects exerted acutely, chronicaly, and in animals with controlled glucocorticoid levels
41. Repeated immobilization stress alters tyrosine hydroxylase, corticotrophin-releasing hormone and corticosteroid receptor messenger ribonucleic acid levels in rat brain
42. Coordinate regulation of the cyclic AMP system with firing rate and expression of tyrosine hydroxylase in the rat locus coeruleus: Effects of chronic stress and drug treatments
43. Trans-synaptic modulation of rat adrenal tyrosine hydroxylase gene expression during cold stress
44. Regional responses of rat brain noradrenergic neurones to acute intense stress
45. Induction of tyrosine hydroxylase gene expression by a nonneuronal nonpituitary-mediated mechanism in immobilization stress
46. Prior exposure to chronic stress results in enhanced synthesis and release of hippocampal norepinephrine in response to a novel stressor
47. Enhanced tyrosine hydroxylation in hippocampus of chronically stressed rats upon exposure to a novel stressor
48. Noradrenergic activation in the paraventricular nucleus during acute and chronic immobilization stress in rats: An in vivo microdialysis study
49. Stress-induced norepinephrine release in the hypothalamic paraventricular nucleus and pituitary-adrenocortical and sympathoadrenal activity: In vivo microdialysis study
50. Stressor-specific activation of catecholaminergic systems: Implications for stress related hypothalamic-pituitary-adrenocortical responses
51. Heterogenous neurochemical responses to different stressors: A test of Selye's doctrine of nonspecificity
52. Locus coeruleus activation by physiological challenges
53. Interconnections between the neuroendocrine hypothalamus and the central autonomic system
54. Neuronal organization of stress response, Pain-induced c-fos expression in brain stem catecholaminergic cell groups
55. Stress induced Fos-like immunoreactivity in the pons and the medulla oblongata of rats
56. Catecholaminergic modulation of corticotropin-releasing factor and adrenocorticotropin secretion
57. Activation of brainstem catecholaminergic neurons by conditioned and unconditioned aversive stimuli as revealed by c-Fos immunoreactivity
58. Modulation of tyrosine hydroxylase gene expression in rat brain and adrenals by exposure to cold
59. Subgroups of hindbrain catecholamine neurons are selectively activated by 2-deoxy-D-glucose induced metabolic challenge
60. Individual differences in behavioral reactivity: Correlation with stress-induced norepinephrine efflux in the hippocampus of Sprague-Dawley rats
61. Different effects of insulin and 2-deoxy-D-glucose administration on tyrosine hydroxylase gene expression in the locus coeruleus and the adrenal medulla in rats
62. Tyrosine hydroxylase mRNA levels in locus coeruleus of rats during adaptation to long-term immobilization stress exposure
63. Effect of various stressors on the activity of locus coeruleus neurons in long-term repeatedly immobilized rats
64. Effects of acute restraint stress on tyrosine hydroxylase mRNA expression in locus coeruleus of Wistar and Wistar-Kyoto rats
65. Stress induced c-fos expression in the brain: Activation mechanism of sympathetic pathway
66. Stress induced expression of immediate early genes in the brain and peripheral organs of the rat
67. The response pattern of noradrenaline release to repeated stress in the hypothalamic paraventricular nucleus differs according to the form of stress in rats
68. CRF receptor antagonist attenuates immobilization stress-induced norepinephrine release in the prefrontal cortex in rats
69. Effects of stress and adrenalectomy on tyrosine hydroxylase mRNA levels in the locus coeruleus by in situ hybridization
70. Effect of pentylenetetrazol on the expression of tyrosine hydroxylase mRNA and norepinephrine and dopamine transporter mRNA
71. Hypothalamic cholinergic activity and 2-deoxyglucose-induced hyperglycemia
72. Repeated stress reduces the subsequent stress-induced expression of Fos in rat brain
73. Activation of the locus coeruleus brain noradrenergic system during stress: Circuitry, consequences, and regulation
74. Glucoprivation by insulin leads to trans-synaptic increase in rat adrenal tyrosine hydroxylase mRNA levels
75. ACTH and corticosterone secretion following 2-deoxyglucose administration in intact and in hypothalamic deafferentated male rats
76. Characterization of the 2-deoxy-glucose effect on the adrenocortical axis
77. Effect of acute or repeated stress on behavior and brain norepinephrine system in Wistar-Kyoto (WKY) rats
78. Excitatory influence of the locus coeruleus in hypothalamic-pituitary-adrenocortical axis responses to stress