Negative Glucocorticoid Regulation of Cyclic Adenosine 3′,5′-Monophosphate-Stimulated Corticotropin-Releasing Hormone-Reporter Expression in AtT-20 Cells

Molecular Endocrinology

Volumn 10, Issue 3, 1996, Pages 317-329

  Guardiola Diaz, Hebe M ^a   Kolinske, J Shonee ^a   Gates, Linda H ^a   Seasholtz, Audrey F ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; CYCLIC AMP; DEXAMETHASONE; CHLORAMPHENICOL ACETYLTRANSFERASE; FORSKOLIN; HYBRID PROTEIN;

ARTICLE; CORTICOTROPIN RELEASE; DNA SEQUENCE; HUMAN; HUMAN CELL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; ANIMAL; BINDING SITE; BIOSYNTHESIS; CHEMICAL PHENOMENA; COMPARATIVE STUDY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; HYPOPHYSIS TUMOR; MOUSE; PATHOLOGY; PHYSIOLOGY; REGULATORY SEQUENCE; SECOND MESSENGER;

ANIMALS; BINDING SITES; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CORTICOTROPIN-RELEASING HORMONE; CYCLIC AMP; DEPRESSION, CHEMICAL; DEXAMETHASONE; FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; MICE; PITUITARY NEOPLASMS; RECOMBINANT FUSION PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; SECOND MESSENGER SYSTEMS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0029657898     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.10.3.8833660     Document Type: Article

References (49)

1. Roberts JL, Budarf ML, Baxter JD, Herbert E 1979 Selective reduction of proadrenocorticotropin/endorphin proteins and mRNA activity in mouse pituitary tumor cells by glucocorticoids. Biochemistry 18:4907-4915
2. Birnberg NC, Lissitzky JC, Hinman M, Herbert E 1983 Glucocorticoids regulate POMC gene expression in vivo at the levels of transcription and secretion. Proc Natl Acad Sci USA 80:6982-6986
3. Drouin J, Trifiro MA, Plante RK, Nemer M, Eriksson P, Wrange O 1989 Glucocortcoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene expression. Mol Cell Biol 9:5305-5314
4. Brinckerhoff CE, Plucinska IM, Sheldon LA, O'Connor GT 1986 Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all-trans retinoic acid or dexamethasone. Biochemistry 25:6378-6384
5. Jonat C, Rahmsdorf HJ, Park K-K, Cato ACB, Gebel S, Ponta H, Herrlich P 1990 Antitumor promotion and antiinflammation: down-modulation of AP-1 (fos/jun) activity by glucocorticoid hormone. Cell 62:1189-1204
6. Akerblom IE, Slater EP, Beato M, Baxter JD, Mellon PL 1988 Negative regulation by glucocorticoids through interference with a cAMP responsive element. Science 241:350-353
7. Chatterjee VKK, Madison LD, Mayo S, Jameson JL 1991 Repression of the human glycoprotein hormone alpha subunit gene by glucocorticoids:evidence for receptor interactions with limiting transcriptional activators. Mol Endocrinol 5:100-110
8. Camper SA, Yao YA, Rottman FM 1985 Hormonal regulation of the bovine prolactin promoter in rat pituitary tumor cells. J Biol Chem 260:12246-12251
9. Sakai DD, Helms S, Carlstedt-Duke J, Gustafsson JA, Rottman FM, Yamamoto KR 1988 Hormone-mediated repression: a negative glucocorticoid responsive element from the bovine prolactin gene. Genes Dev 2:1144-1154
10. Diamond MI, Miner JN, Yoshinaga SK, Yamamoto KR 1990 Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science 249:1266-1272
11. Morrison N, Eisman J 1993 Role of the negative glucocorticoid regulatory element in glucocorticoid repression of the human osteocalcin promoter. J Bone Miner Res 8:969-975
12. Young WS, Mezey E, Siegel RE 1986 Quantitative in situ hybridization histochemistry reveals increased levels of corticotropin-releasing factor mRNA after adrenalectomy in rats. Neurosci Lett 70:198-203
13. Jingami H, Matsukura S, Numa S, Imura H 1985 Effects of adrenalectomy and dexamethasone administration on the level of preprocorticotropin-releasing factor messenger ribonucleic acid (mRNA) in the hypothalamus and adrenocorticotropin/β-lipotropin precursor mRNA in the pituitary in rats. Endocrinology 117:1314-1320
14. Beyer HS, Matta SG, Sharp BM 1988 Regulation of the mRNA for corticotropin-releasing factor in the paraventricular nucleus and other brain sites of the rat. Endocrinology 123:2117-2123
15. Kovacs KJ, Mezey E 1987 Dexamethasone inhibits corticotropin-releasing factor gene expression in the rat paraventricular nucleus. Neuroendocrinology 46:365-368
16. Lightman SL, Young WS 1989 Influence of steroids on the hypothalamic corticotropin-releasing factor and preproenkephalin mRNA responses to stress. Proc Natl Acad Sci USA 86:4306-4310
17. Swanson LW, Simmons DM 1989 Differential steroid hormone and neural influences on peptide mRNA levels in CRH cells of the paraventricular nucleus: a hybridization histochemical study in the rat. J Comp Neurol 285:413-435
18. Kovacs K, Kiss JZ, Makara GB 1986 Glucocorticoid implants around the hypothalamaic paraventricular nucleus prevent the increase of corticotropin-releasing factor and arginine vasopressin immunostaining induced by adrenalectomy. Neuroendocrinology 44:229-234
19. Sawchenko PE 1987 Adrenalectomy-induced enhancement of CRF and vasopressin immunoreactivity in parvocellular neurosecretory neurons: anatomic, peptide, and steroid specificity. J Neurosci 7:1093-1106
20. Sawchenko PE 1987 Evidence for a local site of action for glucocorticoids in inhibiting CRF and vasopressin expression in the paraventricular nucleus. Brain Res 403: 213-224
21. Watanabe H, Orth DN, Toft DO 1973 Glucocorticoid receptors in pituitary tumor cells. J Biol Chem 248:7625-7630
22. Adler GK, Smas CM, Majzoub JA 1988 Expression and dexamethasone regulation of the human corticotropin-releasing hormone gene in a mouse anterior pituitary cell line. J Biol Chem 263:5846-5852
23. Rosen LB, Majzoub JA, Adler GK 1992 Effects of glucocorticoid on corticotropin-releasing hormone gene regulation by second messenger pathways in NPLC and AtT-20 cells. Endocrinology 130:2237-2244
24. Guardiola-Diaz H, Seasholtz AF, Mechanistic studies on the differential regulation of the h CRH gene by glucocorticoids. Program of the American Society for Biochemistry and Molecular Biology, San Diego, CA, 1993, p 1133 (Abstract)
25. Van LP, Spengler DH, Holsboer F 1990 Glucocorticoid repression of 3′,5′-cyclic-adenosine monophosphate-dependent human corticotropin-releasing hormone gene promoter activity in a transfected mouse anterior pituitary cell line. Endocrinology 127:1412-1418
26. Seasholtz AF, Thompson RC, Douglass JO 1988 Identification of a cyclic adenosine monophosphate-responsive element in the rat corticotropin-releasing hormone gene. Mol Endocrinol 2:1311-1319
27. Guardiola-Diaz H, Boswell C, Seasholtz AF 1994 The cAMP-responsive element in the corticotropin-releasing hormone gene mediates transcriptional regulation by depolarization. J Biol Chem 269:14784-14791
28. Spengler D, Rupprecht R, Van, LP, Holsboer F 1992 Identification and characterization of a 3′-5′-cyclic adenosine monophosphate-responsive element in the human corticotropin-releasing hormone gene promoter. Mol Endocrinol 6:1931-1941
29. Prost E, Moore DD 1986 CAT vectors for analysis of eukaryotic promoters and enhancers. Gene 45:107-111
30. Krushner PJ, Baxter JD, Duncan KG, Lopez GN, Schaufele F, Uht RM, Webb P, West BL 1994 Eukaryotic regulatory elements lurking in piasmid DNA: the activator protein-1 site in pUC. Mol Endocrinol 8:405-407
31. Cato AC, Miksicek R, Schutz G, Amemann J, Beato M 1986 The hormone regulatory element of mouse mammary tumor virus mediates progesterone induction. EMBO J 5:2237-2240
32. Miyazaki K, Reisine T, Kebabian JW 1984 Adenosine 3′,5′-Monophosphate (cAMP)-dependent protein kinase activity in rodent pituitary tissue: possible role in cAMP-depenent hormone secretion. Endocrinology 115:1933-1945
33. Adler GK, Smas CM, Fiandaca M, Frim DM, Majzoub JA 1990 Regulated expression of the human corticotropin releasing hormone gene by cyclic AMP. Mol Cell Endocrinol 70:165-174
34. Dorin RI, Takahashi H, Nakai Y, Fukata J, Naitoh Y, Imura H 1989 Regulation of human corticotropin-releasing hormone gene expression by 3′,5′-cyclic adenosine monophosphate in a transformed mouse corticotroph cell line. Mol Endocrinol 3:1537-1544
35. Freedman LP, Luisi BF, Korszun ZR, Basavappa R, Sigler PB, Yamamoto KA 1988 The function and structure of the metal coordination sites within the glucocorticold receptor DNA-binding domain. Nature 334:543-546
36. Payvar F, DeFranco D, Firestone GL, Edgar B, Wrange O, Okret S, Gustafsson JA, Yamamoto KR 1983 Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region. Cell 35:381-392
37. Majzoub JA, Emmanuel R, Adler G, Martinez C, Robinson B, Wittert G 1993 Second messenger regulation of mRNA for corticotropin-releasing factor. In: Vale W (ed) Corticotropin-Releasing Factor. John Wiley & Sons, West Sussex, U.K., pp 30-57
38. Xing L, Quinn P 1993 Involvement of cAMP-regulatory element binding protein (CREB) in both basal and hormone-mediated expresesion of the phosphoenolpyruvate carboxykinase (PEPCK) gene. Mol Endocinol 7:1484-1494
39. Schule R, Rangarajan P, Kliewer S, Ransone LJ, Bolado J, Yang N, Verma IM, Evans RN 1990 Functional antagonism between oncoprotein c-jun and the glucocorticoid receptor. Cell 62:1217-1226
40. Yang-Yen H-F, Chambard J-C, Sun Y-L, Smeal T, Schmidt TJ, Drouin J, Karin M 1990 Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62:1205-1215
41. Stauber C, Altschmied J, Akerblom IE, Marron JL, Mellon PL 1992 Mutual cross-interference between glucocorticoid receptor and CREB inhibits transactivation in placental cells. New Biol 4:527-540
42. Nemeroff CB, Widerlov E, Bissette G, Walleus H, Karlsson I, Eklund K, Kilts CD, Loosen PT, Vale W 1984 Elevated concentration of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients. Science 226:1342-1344
43. Kaye WH, Gwirtsman HE, George DT, Ebert NH, Jimerson DC, Tomai TP, Chrousos GP, Gold PW 1987 Elevated cerebrospinal fluid levels of immunoreactive corticotropin-releasing hormone in anorexia nervosa: relation to state of nutrition, adrenal function, and intensity of depression. J Clin Endocrinol Metab 64:203-208
44. Gorman CM, Moffat LF, Howard BH 1982 Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 2:1044-1051
45. Sadowski I, Cell B, Broad P, Hollis M 1992 GAL4 fusion vectors for expression in yeast or mammalian cells. Gene 118:137-141
46. Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ 1979 Isolation of biologically active ribonucleic acid from sources enriched for ribonuclease. Biochemistry 18: 5294-5299
47. Ausubel FM (ed) 1991 Current Protocols in Molecular Biology. John Wiley & Sons, New York, pp 4.7.1-4.7.8
48. Johnson MR, Bruzdzinski CJ, Winograd SS, Gelehrter TD 1992 Regulatory sequences and protein-binding sites involved in the expression of the rat plasminogen activator inhibitor-1 gene. J Biol Chem 267:12202-12210
49. Maxam AM, Gilbert W 1980 Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol 65:499-560