Substance P is involved in terminating the hypothalamo-pituitary-adrenal axis response to acute stress through centrally located neurokinin-1 receptors

Stress

Volumn 3, Issue 3, 2000, Pages 209-220

  Jessop, David S ^a   Renshaw, Derek ^a,b,c   Larsen, Philip J ^a,b,c   Chowdrey, Hardial S ^a,b,c   Harbuz, Michael S ^a,b,c  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF WESTMINSTER   (United Kingdom)

Author keywords

ACTH; Corticosterone; CRF; POMC; RP67580; Substance P. rat

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; NEUROKININ 1 RECEPTOR; SUBSTANCE P;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS PERIVENTRICULAR NUCLEUS; IMMOBILIZATION STRESS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING;

EID: 0033948642     PISSN: 10253890     EISSN: None     Source Type: Journal    
DOI: 10.3109/10253890009001125     Document Type: Article

References (48)

1. Arai, H. & Emson, P.C. (1986) Regional distribution of neuropeptide K and other tachykinins in rat central nervous system. Brain Res., 399,240-249.
2. Bittencourt, J.C., Benoît, R. & Sawchenko, P.E. (1991) Distribution and origins of substance P-immunoreactive projections to the paraventricular and supraoptic nuclei: Partial overlap with ascending catecholaminergic projections. J. Chem. Neuroanat., 4, 63-78.
3. Buckingham, J.C., Cowell, A-M., Gillies, G.E., Herbison, A.E. & Steel, J.H. (1997) The neuroendocrine system: anatomy, physiology and responses to stress. In J.C. Buckingham, A-M. Cowell and G.E. Gillies (Eds), Stress, Stress Hormones and the Immune System. John Wiley and Sons, Chichester, pp9-47.
4. Chang, M.M. & Leeman, S.E. (1970) Isolation of a sialogogic peptide from bovine hypothalamic tissue and its characterization - as substance P. J. Biol. Cliem., 245, 4784-4790.
5. Chowdrey, H.S., Jessop, D.S. & Lightman, S.L. (1990) Substance P stimulates arginine vasopressin and inhibits adrenocorticotropin release in the rat. Neiirocndocrinol., 52, 90-93.
6. Chowdrey, H.S, Larsen, P.J., Harbuz, M.S., Lightman, S.L. & Jessop, D.S. (1995) Endogenous substance P inhibits the expression of CRH during a chronic inflammatory stress. Life Sci., 57,2021-2029.
7. Clarke, 1., Jessop, D., Millar, R., Morris, M., Bloom, S., Lightman, S., Coen, C., Lew, R. & Smith, A. (1993) Many peptides that are present in the external zone of the median eminence are not secreted into the hypophysial portal blood of sheep. Neuroenihcrinol., 57, 765-775.
8. Culman, J., Wiegand, B., Spitznagel, H., Klee, S. & Unger, T. (I995a) Effects of the tachykinin NK1 receptor antagonist, RP67580, on central cardiovascular and behavioural effects of substance P, neurokinin A and neurokinin B. Brit. J. PhannacoJ., 114, 1310-1316.
9. Culman, J., Itoi, K. & Unger, T. (1995b) Hypothalamic tachykinins: mediators of stress responses? Ann. NYAcad. Sci. U.S.A., 771, 204-218.
10. Culman, J., Klee, S., Ohlendorf, C., & Unger, T. (1997) Effect of tachykinin receptor inhibition in the brain on cardiovascular and behavioural responses to stress. J. Phannacol. Exp. Ther., 280,238-246.
11. Eckstein, N., Wehrenberg, W., Louis, K., Carmel, P., Zimmerman, E., Frantz, A. & Ferin, M. (1980) Effects of substance P on anterior pituitary secretion in the female rhesus monkey. Neitroendocrinol., 31, 338-342.
12. Faria, M., Navarra, P., Tsagarakis, S., Besser, G.M. & Grossman, A.B. (1991) Inhibition of CRH-41 release by substance P, but not substance K, from the rat hypothalamus in vitro. Brain Res., 538, 76-78.
13. Garret, C., Carruette, A., Fardin, V., Moussaoui, S., Peyronel, J.F., Blanchard, J.C. & Laduron, P.M. (1991) Pharmacological properties of a potent and selective nonpeptide Substance P antagonist. Proc. Natl. Acad. Sci. U.S.A., 88, 10208-10212.
14. Hahn, M.K. & Bannon, M.J. (1998) Tachykinin NK1 receptor antagonists enhance stress-induced c-fos in rat locus coeruleus. Ear. J. Phannacol., 348, 155-160.
15. Harbuz, M.S. & Lightman, S.L. (1989) Responses of hypothalamic and pituitary mRNA to physical and psychological stress in the rat. J. Endocrinol., 134, 705-711.
16. Harbuz, M.S., Jessop, D.S., Lightman, S.L. & Chowdrey, H.S. (1994) The effects of restraint or hypertonic saline stress on corticotrophin-releasing factor, arginine vasopressin, and proenkephalin A rnRNAs in the CFY, Sprague-Dawley and Wistar strains of rat. Brain Res., 667, 6-12.
17. Hökfelt, T., Pernow, B., Nilsson, G., Wetterburg, L., Goldstein, M. & Jeffcoate, S. (1978) Dense plexus of substance P immunoreactive nerve terminals in eminentia terminalis of the primate hypothalamus. Proc. Natl. Acad. Sci. U.S.A., 75, 1013-1015.
18. Holmes, M.C., Di Renzo, G., Beckford, U., Gillham, B. & Jones, M.T. (1982) Role of serotonin in the control of secretion of corticotrophin-releasing factor. J. Endocrinol., 93, 151-160.
19. Jessop, D.S., Eckland, D.J.A., Todd, K. & Lightman, S.L. (1989) Osmotic regulation of hypothalamo-neurointermediate lobe corticotrophin-releasing factor-41 in the rat. J. Endocrinol., 120,119-124.
20. Jessop, D.S., Chowdrey, H.S., Larsen, P.J. & Lightman, S.L. (1992) Substance P: multifunctional peptide in the hypothalamo-pituitary system?/ Endocrinol., 132, 331-337.
21. Jessop, D.S. (1999) Central non-glucocorticoid inhibitors of the hypothalamo-pituitary-adrenal axis. J. Endocrinol., 160, 169180.
22. Kennett, G. & Joseph, M. (1981) The functional importance of increased brain tryptophan in the serotonergic response to restraint stress. Neuropliannacol., 20, 39-43.
23. Ku, Y-H., Tan, L., Li, L-S. & Ding, X. (1998) Role of corticotropin-releasing factor and substance P in pressor responses of nuclei controlling emotion and stress. Peplides 19, 677-682.
24. Larsen, P.J. (1992) Distribution of substance P-immunoreactive elements.in. the preoptic area and hypothalamus of the rat. J. Comp. Neural., 316, 287-313.
25. Larsen, P.J., Jessop, D.S., Chowdrey, H.S., Mikkelsen, J.D. & Lightman, S.L. (1992) Osmotic regulation of substance P and neurokinin A peptide content and substance P binding sites in distinct hypothalamic nuclei of the rat. Peplides 13,705-712.
26. Larsen, P.J., Jessop, D.S., Patel, H., Lightman, S.L. & Chowdrey, H.S. (1993a) Substance P inhibits the release of anterior pituitary adrenocorticotrophin via a central mechanism involving corticotrophin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus. J. Neuroeiidocrinol., 5, 99-105.
27. Larsen, P.J., Jessop, D.S., Lightman, S.L. & Chowdrey, H.S. (1993b) Preprotachykinin A gene expression in distinct hypothalamic and brain stem areas of the rat is affected by a . chronic osmotic stimulus: a combined immunohistochemical and in situ hybridisation histochemistry study. Brain Res. Bull., 30,535-545.
28. Lim, A., Sheward, W., Copolov, D., Windmill, D. & Fink, G. (1990) Atrial natriuretic factor is released into hypophysial portal blood: direct evidence that atrial natriuretic factor may be a neurohormone involved in hypothalamic pituitary control. J. Neuroeiidocrinol., 2, 15-18.
29. Liposits, Zs., Phelix, C. & Paull, W. (1987) Synaptic interaction of serotonergic axons and corticotropin releasing factor (CRF) synthesising neurons in the hypothalamic paraventricular nucleus of the rat. Histochem., 86, 541-549.
30. Ljungdahl, A., Hökfelt, T. & Nilsson, G. (1978) Distribution of substance P-like immunoreactivity in the central nervous system of the rat. Netirosci., 3,861-880.
31. Mai, J., Stephens, P., Hope, A. & Cuello., C. (1986) Substance P in the human brain. Neurosci., 17, 709-739.
32. Makara, G. & Stark, E. (1974) Effect of y-ABA and y-ABA antagonistic drugs on ACTH release. Neuroendocrinol., 16, 178190.
33. Malendowicz, L.K., Andreis, P.C., Nussdorfer, G.G. & Markowska, A. (1996) The possible role of endogenous substance P in the modulation of the response of rat pituitary-adrenal axis to stresses. Endocr. Res., 22, 311-318.
34. Mantyh, P., Gales, T., Mantyh, C. & Maggio, J. (1989) Autoradiographie localisation and characterisation of tachykinin receptor binding sites in the rat brain and peripheral tissues. J. Neurosci., 9, 258-279.
35. Meister, B., Hökfelt, T., Geffard, M. & Derlei, W. (1988) Glutamic acid decarboxylase and y-aminobutyric acid-like immunoreactivities in corticotropin-releasing factor-containing parvocellular neurons of the hypothalamic paraventricular nucleus. NeuroendocrinoL, 48, 516-526.
36. Mikkelsen, J., Larsen, R, Möller, M., Vilhardt, H. & Srmark, T. (1989) Substance P in the median eminence and pituitary of the rat: demonstration of immunoreactive fibers and specific binding sites. Neuroendocrinol., 50, 100-108.
37. Munck, A. & Naray-Fejes-Toth, A. (1994) Glucocorticoids and stress: Permissive and suppressive actions. Ann. NYAcad. Sci. U.S.A.,146, 115-130.
38. Nicholson, S.A., Afiran, T.E., Giliham, B., Jones, M.T. & Bloom, S.R. (1984) Effect of hypothalamic neuropeptides on corticotrophin release from quarters of rat anterior pituitary gland in vitro. J. Endocrinol., 100, 219-226.
39. Nussdorfer, G.G. & Malendowicz, L.K. 1998 Role of tachykinins in the regulation of the hypothalamo-pituitary-adrenal axis. Peplides 19, 949-968.
40. Otsuka, M. & Yoshioka, K. (1993) Neurotransmitler functions of mammalian tachykinins. Physiol. Rev., 73, 229-308.
41. Owens, M.J., Knight, D.L., Ritchie, J.C. & Nemeroff, C.B. (1991) The 5-hydroxytryptamine 2 agonist, (+-)-l-(2,5-dimethoxy-4-bromophenyI)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. I. Acute effects on HPA axis activity and corticotropin-releasing factor-containing neurons in the rat brain. J. Pharmacol. Exp. Tlter., 256, 787-794.
42. Quartara, L. & Maggi, C.A. (1997) The tachykinin NK, receptor. Part 1: ligands and mechanisms of cellular activation. Nenropeptides 31, 537-563.
43. Quartara, L. & Maggi, C.A. (1998) The tachykinin NK1 receptor. Part II: distribution and pathophysiological roles. NeurppepIiiles32, 1-49.
44. Rdnnekleiv, L., Kelly, M. & Eskay, R. (1984) Distribution of immunoreactive substance P neurons in the hypothalamus and pituitary of the rhesus monkey. J. Coinp. Neural., 224, 51-59.
45. Sakuma, M., Yoshioka, K., Suzuki, H., Yanagisawa, M., Onishi, Y., Kobayashi, N. & Otsuka, M. (1991) Substance P-evoked release of GABA from isolated spinal cord of the newborn rat. Neurosci., 45, 323-330.
46. Saphier, D., Welch, J., Farrar, G., Nguyen, N., Aguado, F., Thaller, T. & Knight, D. (1994) Interactions between serotonin, thyrotropin-releasing hormone, and substance P in the CNS regulation of adrenocortical secretion. Psychoneiirocndocrinol., 19, 779-797.
47. Unger, T., Becker, H., Petty, M., Demmert, G., Schneider, B., Ganten, D. & Lang, R.E. (1985) Differential effects of central angiotensin II and substance P on sympathetic nerve activity in conscious rats. Circ. Res., 56, 563-575.
48. Unger, T., Carolus, S., Demmert, G., Ganten, D., Lang, R.E., Maser-Gluth, C., Steinberg, H. & Veelken, R. (1988) Substance P induces a cardiovascular defense reaction in the rat: Pharmacological characterization. Circ. Res., 63,812-820.