Metabolic Engineering of Escherichia coli for Natural Product Biosynthesis

Trends in Biotechnology

Volumn 38, Issue 7, 2020, Pages 745-765

  Yang, Dongsoo ^a   Park, Seon Young ^a   Park, Yae Seul ^a   Eun, Hyunmin ^a   Lee, Sang Yup ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

E. coli; enzyme engineering; metabolic flux optimization; natural products; systems metabolic engineering

Indexed keywords

ADDITIVES; BIOCHEMISTRY; BIOSYNTHESIS; CELL ENGINEERING; ESCHERICHIA COLI; METABOLISM;

E. COLI; ENZYME ENGINEERING; METABOLIC FLUX; NATURAL PRODUCTS; SYSTEMS METABOLIC ENGINEERINGS;

METABOLIC ENGINEERING;

ALKALOID; ANTHRANILIC ACID METHYL ESTER; CHAPERONE; COSMETIC; DEOXYVIOLACEIN; ECHINOMYCIN; ERYTHROMYCIN; FOOD ADDITIVE; HEME; INDIGO; INDIRUBIN; MUTANT PROTEIN; NATURAL PRODUCT; NUTRACEUTICAL; OPIATE; PACLITAXEL; PHENYLPROPANOID DERIVATIVE; POLYKETIDE; RESVERATROL; TERPENOID; UNCLASSIFIED DRUG; VIOLACEIN; YERSINIABACTIN; BIOLOGICAL PRODUCT;

ADAPTIVE LABORATORY EVOLUTION; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIUM CULTURE; BIOSYNTHESIS; CELL DENSITY; COMPUTER ANALYSIS; DRUG SYNTHESIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; EXTRACTION; GENE EXPRESSION LEVEL; GENOME; HIGH THROUGHPUT SCREENING; LABORATORY; MACHINE LEARNING; MEMBRANE; METABOLIC ENGINEERING; NEGATIVE FEEDBACK; NONHUMAN; OMICS; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; REVIEW; CHEMISTRY; GENETICS; HUMAN; METABOLISM; SYNTHETIC BIOLOGY;

BIOLOGICAL PRODUCTS; ESCHERICHIA COLI; HUMANS; METABOLIC ENGINEERING; SYNTHETIC BIOLOGY;

EID: 85077559158     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2019.11.007     Document Type: Review

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