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Volumn 365, Issue 10, 2018, Pages

Metabolic engineering of Escherichia coli for the production of isoprenoids

Author keywords

Escherichia coli; Genetic engineering; Isoprenoids; Metabolic engineering; Methylerythritol pathway; Mevalonate pathway

Indexed keywords

CYTOCHROME P450; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; ISOPRENOID; MEVALONIC ACID; TERPENE;

EID: 85050632805     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1093/femsle/fny079     Document Type: Short Survey
Times cited : (55)

References (98)
  • 1
    • 42549093749 scopus 로고    scopus 로고
    • Terpenoids: opportunities for biosynthesis of natural product drugs using engineered microorganisms
    • Ajikumar PK, Tyo K, Carlsen S et al. Terpenoids: opportunities for biosynthesis of natural product drugs using engineered microorganisms. Mol Pharmaceutics 2008;5:167-90
    • (2008) Mol Pharmaceutics , vol.5 , pp. 167-190
    • Ajikumar, P.K.1    Tyo, K.2    Carlsen, S.3
  • 2
    • 77957329119 scopus 로고    scopus 로고
    • Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli
    • Ajikumar PK, XiaoW, Tyo KEJ et al. Isoprenoid pathway optimization for taxol precursor overproduction in Escherichia coli. Science 2010;330:70-4
    • (2010) Science , vol.330 , pp. 70-74
    • Ajikumar, P.K.1    Xiao, W.2    Tyo, K.E.J.3
  • 4
    • 84879829307 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production
    • Alonso-Gutierrez J, Chan R, Batth TS et al. Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production. Metab Eng 2013;19:33-41
    • (2013) Metab Eng , vol.19 , pp. 33-41
    • Alonso-Gutierrez, J.1    Chan, R.2    Batth, T.S.3
  • 5
    • 18844392599 scopus 로고    scopus 로고
    • Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli
    • Alper H, Jin Y, Moxley JF et al. Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli. Metab Eng 2005;7:155-64
    • (2005) Metab Eng , vol.7 , pp. 155-164
    • Alper, H.1    Jin, Y.2    Moxley, J.F.3
  • 6
    • 55549116661 scopus 로고    scopus 로고
    • Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4, 11-diene
    • Anthony JR, Anthony LC, Nowroozi F et al. Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4, 11-diene. Metab Eng 2009;11:13-19
    • (2009) Metab Eng , vol.11 , pp. 13-19
    • Anthony, J.R.1    Anthony, L.C.2    Nowroozi, F.3
  • 7
    • 0023039987 scopus 로고    scopus 로고
    • Detergent-solubilization, purification, and characterization of membrane-bound 3-hydroxy-3-methylglutaryl-coenzyme A reductase from radish seedlings
    • Bach TJ, Rogers DH, Rudney H. Detergent-solubilization, purification, and characterization of membrane-bound 3-hydroxy-3-methylglutaryl-coenzyme A reductase from radish seedlings. Eur J Biochem 2000;1:103-11
    • (2000) Eur J Biochem , vol.1 , pp. 103-111
    • Bach, T.J.1    Rogers, D.H.2    Rudney, H.3
  • 8
    • 0032005917 scopus 로고    scopus 로고
    • Cloning of three A-type cytochromes P450, CYP71E1, CYP98, and CYP99 from Sorghum bicolor (L.) Moench by a PCR approach and identification by expression in Escherichia coli of CYP71E1 as a multifunctional cytochrome P450 in the biosynthesis of the cyanogen glucoside dhurrin
    • Bak S, Kahn RA, Nielsen HL et al. Cloning of three A-type cytochromes P450, CYP71E1, CYP98, and CYP99 from Sorghum bicolor (L.) Moench by a PCR approach and identification by expression in Escherichia coli of CYP71E1 as a multifunctional cytochrome P450 in the biosynthesis of the cyanogen glucoside dhurrin. Plant Mol Biol 1998;36: 393-405
    • (1998) Plant Mol Biol , vol.36 , pp. 393-405
    • Bak, S.1    Kahn, R.A.2    Nielsen, H.L.3
  • 9
    • 84878768243 scopus 로고    scopus 로고
    • Feedback inhibition of Deoxyd-xylulose-5-phosphate synthase regulates the methylerythritol 4-Phosphate pathway
    • Banerjee A, Wu Y, Banerjee R et al. Feedback inhibition of Deoxyd-xylulose-5-phosphate synthase regulates the methylerythritol 4-Phosphate pathway. J Biol Chem 2013;288:16926-36
    • (2013) J Biol Chem , vol.288 , pp. 16926-16936
    • Banerjee, A.1    Wu, Y.2    Banerjee, R.3
  • 10
    • 84867838237 scopus 로고    scopus 로고
    • 2C-Methyl-D-erythritol 4-Phosphate enhances and sustains cyclodiphosphate synthase IspF activity
    • Bitok JK, Meyers CF. 2C-Methyl-D-erythritol 4-Phosphate enhances and sustains cyclodiphosphate synthase IspF activity. ACS Chem Biol 2012;7:1702-10
    • (2012) ACS Chem Biol , vol.7 , pp. 1702-1710
    • Bitok, J.K.1    Meyers, C.F.2
  • 11
    • 84857918189 scopus 로고    scopus 로고
    • Computational identification of gene over-expression targets for metabolic engineering of taxadiene production
    • Boghigian BA, Armando J, Salas D et al. Computational identification of gene over-expression targets for metabolic engineering of taxadiene production. Appl Microbiol Biot 2012;93:2063-73
    • (2012) Appl Microbiol Biot , vol.93 , pp. 2063-2073
    • Boghigian, B.A.1    Armando, J.2    Salas, D.3
  • 12
    • 0016664365 scopus 로고
    • Properties of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase from pisum sativum seedlings
    • Brooker D, Russell W. Properties of microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase from pisum sativum seedlings. Arch Biochem Biophys 1975;167:723-9
    • (1975) Arch Biochem Biophys , vol.167 , pp. 723-729
    • Brooker, D.1    Russell, W.2
  • 13
    • 34247182988 scopus 로고    scopus 로고
    • Engineering Escherichia coli for production of functionalized terpenoids using plant P450s
    • Chang MCY, Eachus RA, Trieu W et al. Engineering Escherichia coli for production of functionalized terpenoids using plant P450s. Nat Chem Biol 2007;3:274-7
    • (2007) Nat Chem Biol , vol.3 , pp. 274-277
    • Chang, M.C.Y.1    Eachus, R.A.2    Trieu, W.3
  • 14
    • 84887997172 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli: a sustainable industrial platform for bio-based chemical production
    • Chen X, Zhou L, Tian K et al. Metabolic engineering of Escherichia coli: a sustainable industrial platform for bio-based chemical production. Biotechnol Adv 2013;31:1200-23
    • (2013) Biotechnol Adv , vol.31 , pp. 1200-1223
    • Chen, X.1    Zhou, L.2    Tian, K.3
  • 15
    • 77952265112 scopus 로고    scopus 로고
    • In silico identification of gene amplification targets for improvement of lycopene production
    • Choi HS, Lee SY, Kim TY et al. In silico identification of gene amplification targets for improvement of lycopene production. Appl Environ Microb 2010;76:3097-105
    • (2010) Appl Environ Microb , vol.76 , pp. 3097-3105
    • Choi, H.S.1    Lee, S.Y.2    Kim, T.Y.3
  • 16
    • 0034731616 scopus 로고    scopus 로고
    • The commercial production of chemicals using pathway engineering
    • Chotani G, Dodge T, Hsu A et al. The commercial production of chemicals using pathway engineering. Biochem Biophys Acta 2000;1543:434-55
    • (2000) Biochem Biophys Acta , vol.1543 , pp. 434-455
    • Chotani, G.1    Dodge, T.2    Hsu, A.3
  • 17
    • 65649123015 scopus 로고    scopus 로고
    • A novel semibiosynthetic route for artemisinin production using engineered substrate-promiscuous P450 BM3
    • Dietrich JA, Yoshikuni Y, Fisher KJ et al. A novel semibiosynthetic route for artemisinin production using engineered substrate-promiscuous P450 BM3. ACS Chem Biol 2009;4:261-7
    • (2009) ACS Chem Biol , vol.4 , pp. 261-267
    • Dietrich, J.A.1    Yoshikuni, Y.2    Fisher, K.J.3
  • 18
    • 85039837517 scopus 로고    scopus 로고
    • Synthesis of heterologous mevalonic acid pathway enzymes in Clostridium ljungdahlii for the conversion of fructose and of syngas to mevalonate and isoprene
    • Diner BA, Fan J, Scotcher MC et al. Synthesis of heterologous mevalonic acid pathway enzymes in Clostridium ljungdahlii for the conversion of fructose and of syngas to mevalonate and isoprene. Appl Environ Microb 2018;84:1-16
    • (2018) Appl Environ Microb , vol.84 , pp. 1-16
    • Diner, B.A.1    Fan, J.2    Scotcher, M.C.3
  • 19
    • 0030772492 scopus 로고    scopus 로고
    • Effects of overproduction of the catalytic domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase on squalene synthesis in Saccharomyces cerevisiae
    • Donald KAG, Hampton RY, Fritz IB. Effects of overproduction of the catalytic domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase on squalene synthesis in Saccharomyces cerevisiae. Appl Environ Microb 1997;63:3341-4
    • (1997) Appl Environ Microb , vol.63 , pp. 3341-3344
    • Donald, K.A.G.1    Hampton, R.Y.2    Fritz, I.B.3
  • 20
    • 85019294885 scopus 로고    scopus 로고
    • Enhanced limonene production by optimizing the expression of limonene biosynthesis andMEP pathway genes in E. coli
    • Du F-L, Yu H-L, Xu J-H et al. Enhanced limonene production by optimizing the expression of limonene biosynthesis andMEP pathway genes in E. coli. Bioresource Bioprocess 2014;1:10
    • (2014) Bioresource Bioprocess , vol.1 , pp. 10
    • Du, F.-L.1    Yu, H.-L.2    Xu, J.-H.3
  • 21
    • 68449088806 scopus 로고    scopus 로고
    • Synthetic protein scaffolds provide modular control over metabolic flux
    • Dueber JE, Wu GC, Malmirchegini GR et al. Synthetic protein scaffolds provide modular control over metabolic flux. Nat Biotechnol 2009;27:753-9
    • (2009) Nat Biotechnol , vol.27 , pp. 753-759
    • Dueber, J.E.1    Wu, G.C.2    Malmirchegini, G.R.3
  • 22
    • 0035128694 scopus 로고    scopus 로고
    • Precursor balancing for metabolic engineering of lycopene production in Escherichia coli
    • Farmer WR, Liao JC. Precursor balancing for metabolic engineering of lycopene production in Escherichia coli. Biotechnol Prog 2001;17:57-61
    • (2001) Biotechnol Prog , vol.17 , pp. 57-61
    • Farmer, W.R.1    Liao, J.C.2
  • 23
    • 85018829159 scopus 로고    scopus 로고
    • The methylerythritol phosphate pathway to isoprenoids
    • Frank A, Groll M. The methylerythritol phosphate pathway to isoprenoids. Chem Rev 2017;117:5675-703
    • (2017) Chem Rev , vol.117 , pp. 5675-5703
    • Frank, A.1    Groll, M.2
  • 24
    • 80052785690 scopus 로고    scopus 로고
    • High-throughput, accurate mass metabolome profiling of cellular extracts by flow injection-time-of-flight mass spectrometry
    • Fuhrer T, Heer D, Begemann B et al. High-throughput, accurate mass metabolome profiling of cellular extracts by flow injection-time-of-flight mass spectrometry. Anal Chem 2011;83:7074-80
    • (2011) Anal Chem , vol.83 , pp. 7074-7080
    • Fuhrer, T.1    Heer, D.2    Begemann, B.3
  • 25
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature 1990;343:425-30
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 26
    • 85050610235 scopus 로고    scopus 로고
    • Physiological effects of 5-hydroxymethylfurfural on Saccharomyces cerevisiae
    • Goswami P, Chinnadayyala SSR, Chakraborty M et al. Physiological effects of 5-hydroxymethylfurfural on Saccharomyces cerevisiae. Appl Microbiol Biot 2013;97:8411-25
    • (2013) Appl Microbiol Biot , vol.97 , pp. 8411-8425
    • Goswami, P.1    Chinnadayyala, S.S.R.2    Chakraborty, M.3
  • 27
    • 84884376873 scopus 로고    scopus 로고
    • In silico profiling of Escherichia coli and Saccharomyces cerevisiae as terpenoid factories
    • Gruchattka E, Hädicke O, Klamt S et al. In silico profiling of Escherichia coli and Saccharomyces cerevisiae as terpenoid factories. Microb Cell Fact 2013;12:1-18
    • (2013) Microb Cell Fact , vol.12 , pp. 1-18
    • Gruchattka, E.1    Hädicke, O.2    Klamt, S.3
  • 28
    • 0032811818 scopus 로고    scopus 로고
    • Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase
    • Hahn FM, Hurlburt AP, Poulter CD et al. Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase. J Bacteriol 1999;181:4499-504
    • (1999) J Bacteriol , vol.181 , pp. 4499-4504
    • Hahn, F.M.1    Hurlburt, A.P.2    Poulter, C.D.3
  • 29
    • 84872732297 scopus 로고    scopus 로고
    • Post-translational events and modifications regulating plant enzymes involved in isoprenoid precursor biosynthesis
    • Hemmerlin A. Post-translational events and modifications regulating plant enzymes involved in isoprenoid precursor biosynthesis. Plant Sci 2013;203-204:41-54
    • (2013) Plant Sci , vol.203-204 , pp. 41-54
    • Hemmerlin, A.1
  • 30
    • 0028786298 scopus 로고
    • Cinnamate 4-hydroxylase from Catharanthus roseus, and a strategy for the functional expression of plant cytochrome P450 proteins as translational fusions with P450 reductase in Escherichia coli
    • Hotze M, Schröder G, Schröder J. Cinnamate 4-hydroxylase from Catharanthus roseus, and a strategy for the functional expression of plant cytochrome P450 proteins as translational fusions with P450 reductase in Escherichia coli. FEBS Lett 1995;374:345-50
    • (1995) FEBS Lett , vol.374 , pp. 345-350
    • Hotze, M.1    Schröder, G.2    Schröder, J.3
  • 31
    • 0036693744 scopus 로고    scopus 로고
    • Metabolic engineering of lactic acid bacteria for the production of nutraceuticals
    • Hugenholtz J, Sybesma W, Groot MN et al. Metabolic engineering of lactic acid bacteria for the production of nutraceuticals. Anton Leeuw 2002;82:217-35
    • (2002) Anton Leeuw , vol.82 , pp. 217-235
    • Hugenholtz, J.1    Sybesma, W.2    Groot, M.N.3
  • 32
    • 33847753939 scopus 로고    scopus 로고
    • Micromolar intracellular hydrogen peroxide disrupts metabolism by damaging iron-sulfur enzymes
    • Jang S, Imlay JA. Micromolar intracellular hydrogen peroxide disrupts metabolism by damaging iron-sulfur enzymes. J Biol Chem 2007;282:929-37
    • (2007) J Biol Chem , vol.282 , pp. 929-937
    • Jang, S.1    Imlay, J.A.2
  • 33
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNAguided DNA endonuclease in adaptive bacterial immunity
    • Jinek M, Chylinski K, Fonfara I et al. A programmable dual-RNAguided DNA endonuclease in adaptive bacterial immunity. Science 2012;337:816-21
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1    Chylinski, K.2    Fonfara, I.3
  • 35
    • 84951739105 scopus 로고    scopus 로고
    • Isopentenyl diphosphate (IPP)-bypass mevalonate pathways for isopentenol production
    • Kang A, George KW, Wang G et al. Isopentenyl diphosphate (IPP)-bypass mevalonate pathways for isopentenol production. Metab Eng 2016;34:25-35
    • (2016) Metab Eng , vol.34 , pp. 25-35
    • Kang, A.1    George, K.W.2    Wang, G.3
  • 36
    • 85017540512 scopus 로고    scopus 로고
    • High-throughput enzyme screening platform for the IPP-bypass mevalonate pathway for isopentenol production
    • Kang A, Meadows CW, Canu N et al. High-throughput enzyme screening platform for the IPP-bypass mevalonate pathway for isopentenol production. Metab Eng 2017;41: 125-34
    • (2017) Metab Eng , vol.41 , pp. 125-134
    • Kang, A.1    Meadows, C.W.2    Canu, N.3
  • 37
    • 85025163180 scopus 로고    scopus 로고
    • Designing a new entry point into isoprenoid metabolism by exploiting fructose-6-phosphate aldolase side reactivity of Escherichia coli
    • King JR, Woolston BM, Stephanopoulos G. Designing a new entry point into isoprenoid metabolism by exploiting fructose-6-phosphate aldolase side reactivity of Escherichia coli. ACS Synth Biol 2017;6:1416-26
    • (2017) ACS Synth Biol , vol.6 , pp. 1416-1426
    • King, J.R.1    Woolston, B.M.2    Stephanopoulos, G.3
  • 38
    • 67651030513 scopus 로고    scopus 로고
    • Biosynthesis of plant isoprenoids: perspectives for microbial engineering
    • Kirby J, Keasling JD. Biosynthesis of plant isoprenoids: perspectives for microbial engineering. Annu Rev Plant Biol 2009;60:335-55
    • (2009) Annu Rev Plant Biol , vol.60 , pp. 335-355
    • Kirby, J.1    Keasling, J.D.2
  • 39
    • 84917742079 scopus 로고    scopus 로고
    • Enhancing Terpene yield from sugars via novel routes to 1-deoxy-D-xylulose 5-phosphate
    • Kirby J, Nishimoto M, Chow RWN et al. Enhancing Terpene yield from sugars via novel routes to 1-deoxy-D-xylulose 5-phosphate. Appl Environ Microb 2015;81:130-8
    • (2015) Appl Environ Microb , vol.81 , pp. 130-138
    • Kirby, J.1    Nishimoto, M.2    Chow, R.W.N.3
  • 40
    • 32044450527 scopus 로고    scopus 로고
    • Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway
    • Ku B, Jeong J, Mijts BN et al. Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway. Appl Environ Microb 2005;71:6578-83
    • (2005) Appl Environ Microb , vol.71 , pp. 6578-6583
    • Ku, B.1    Jeong, J.2    Mijts, B.N.3
  • 41
    • 0001580671 scopus 로고
    • Higher plant terpenoids: A phytocentric overview of their ecological roles
    • Langenheim JH. Higher plant terpenoids: A phytocentric overview of their ecological roles. J Chem Ecol 1994;20:1223-80
    • (1994) J Chem Ecol , vol.20 , pp. 1223-1280
    • Langenheim, J.H.1
  • 42
    • 29544444196 scopus 로고    scopus 로고
    • Chromosomal promoter replacement of the isoprenoid pathway for enhancing carotenoid production in E. coli
    • Larossa RA, Ã WS, Yuan LZ et al. Chromosomal promoter replacement of the isoprenoid pathway for enhancing carotenoid production in E. coli. Metab Eng 2006;8:79-90
    • (2006) Metab Eng , vol.8 , pp. 79-90
    • Larossa, R.A.1    Ã, W.S.2    Yuan, L.Z.3
  • 43
    • 85019608122 scopus 로고    scopus 로고
    • Production of amino acids-genetic and metabolic engineering approaches
    • Lee J, Wendisch VF. Production of amino acids-genetic and metabolic engineering approaches. Bioresource Technol 2017;245:1575-87
    • (2017) Bioresource Technol , vol.245 , pp. 1575-1587
    • Lee, J.1    Wendisch, V.F.2
  • 44
    • 85020113829 scopus 로고    scopus 로고
    • Current status on metabolic engineering for the production of L-aspartate family amino acids and derivatives
    • Li Y, Wei H, Wang T et al. Current status on metabolic engineering for the production of L-aspartate family amino acids and derivatives. Bioresource Technol 2017;245:1588-602
    • (2017) Bioresource Technol , vol.245 , pp. 1588-1602
    • Li, Y.1    Wei, H.2    Wang, T.3
  • 45
    • 84893388611 scopus 로고    scopus 로고
    • Combination of Entner-Doudoroff pathway with MEP increases isoprene production in engineered Escherichia coli
    • Liu H, Sun Y, Ramos KRM et al. Combination of Entner-Doudoroff pathway with MEP increases isoprene production in engineered Escherichia coli. PLoS One 2013;8:1-7
    • (2013) PLoS One , vol.8 , pp. 1-7
    • Liu, H.1    Sun, Y.2    Ramos, K.R.M.3
  • 46
    • 85044678317 scopus 로고    scopus 로고
    • Systems metabolic engineering strategies for the production of amino acids
    • Ma Q, Zhang Q, Xu Q et al. Systems metabolic engineering strategies for the production of amino acids. Synth Syst Biotechnol 2017;2:87-96
    • (2017) Synth Syst Biotechnol , vol.2 , pp. 87-96
    • Ma, Q.1    Zhang, Q.2    Xu, Q.3
  • 47
    • 80555123167 scopus 로고    scopus 로고
    • Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases
    • Ma SM, Garcia DE, Redding-Johanson AM et al. Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases. Metab Eng 2011;13:588-97
    • (2011) Metab Eng , vol.13 , pp. 588-597
    • Ma, S.M.1    Garcia, D.E.2    Redding-Johanson, A.M.3
  • 48
    • 84957436999 scopus 로고    scopus 로고
    • Genome mining of astaxanthin biosynthetic genes from Sphingomonas sp. ATCC 55669 for heterologous overproduction in Escherichia coli
    • Ma T, Zhou Y, Li X et al. Genome mining of astaxanthin biosynthetic genes from Sphingomonas sp. ATCC 55669 for heterologous overproduction in Escherichia coli. Biotechnol J 2016;11:228-37
    • (2016) Biotechnol J , vol.11 , pp. 228-237
    • Ma, T.1    Zhou, Y.2    Li, X.3
  • 49
    • 0038391517 scopus 로고    scopus 로고
    • Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
    • Martin VJJ, Pitera DJ, Withers ST et al. Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nat Biotechnol 2003;21:796-802
    • (2003) Nat Biotechnol , vol.21 , pp. 796-802
    • Martin, V.J.J.1    Pitera, D.J.2    Withers, S.T.3
  • 50
    • 0030058148 scopus 로고    scopus 로고
    • Inhibition of the mevalonate pathway: benefits beyond cholesterol reduction?
    • Massy ZA, Keane WF, Kasiske BL. Inhibition of the mevalonate pathway: benefits beyond cholesterol reduction? Lancet North Am Ed 1996;347:102-3
    • (1996) Lancet North Am Ed , vol.347 , pp. 102-103
    • Massy, Z.A.1    Keane, W.F.2    Kasiske, B.L.3
  • 51
    • 0029969302 scopus 로고    scopus 로고
    • Regulation of 3-hydroxy-3-methylglutaryl-coenzyme a reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo
    • Meigs TE, Roseman DS, Simoni RD et al. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme a reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo. J Biol Chem 1996;271:7916-22
    • (1996) J Biol Chem , vol.271 , pp. 7916-7922
    • Meigs, T.E.1    Roseman, D.S.2    Simoni, R.D.3
  • 52
    • 79957858524 scopus 로고    scopus 로고
    • In silico analysis and experimental improvement of taxadiene heterologous biosynthesis in Escherichia coli
    • Meng H, Wang Y, Hua Q et al. In silico analysis and experimental improvement of taxadiene heterologous biosynthesis in Escherichia coli. Biotechnol Bioproc E 2011;16:205-15
    • (2011) Biotechnol Bioproc E , vol.16 , pp. 205-215
    • Meng, H.1    Wang, Y.2    Hua, Q.3
  • 53
    • 9144224870 scopus 로고    scopus 로고
    • Brassica juncea 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase 1: expression and characterization of recombinant wild-type andmutant enzymes
    • Nagegowda DA, Bach TJ, Chye M. Brassica juncea 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase 1: expression and characterization of recombinant wild-type andmutant enzymes. Biochem J 2004;527:517-27
    • (2004) Biochem J , vol.527 , pp. 517-527
    • Nagegowda, D.A.1    Bach, T.J.2    Chye, M.3
  • 54
    • 84925348793 scopus 로고    scopus 로고
    • Rational design of a synthetic Entner-Doudoroff pathway for improved and controllable NADPH regeneration
    • Ng CY, Farasat I, Maranas CD et al. Rational design of a synthetic Entner-Doudoroff pathway for improved and controllable NADPH regeneration. Metab Eng 2015;29:86-96
    • (2015) Metab Eng , vol.29 , pp. 86-96
    • Ng, C.Y.1    Farasat, I.2    Maranas, C.D.3
  • 55
    • 77949448789 scopus 로고    scopus 로고
    • Metabolic engineering of acetoin and meso-2, 3-butanediol biosynthesis in E. coli
    • Nielsen DR, Yoon SH, Yuan CJ et al. Metabolic engineering of acetoin and meso-2, 3-butanediol biosynthesis in E. coli. Biotechnol J 2010;5:274-84
    • (2010) Biotechnol J , vol.5 , pp. 274-284
    • Nielsen, D.R.1    Yoon, S.H.2    Yuan, C.J.3
  • 56
    • 0033561008 scopus 로고    scopus 로고
    • Roles of key activesite residues in flavocytochrome P450 BM3
    • Noble MA, Miles CS, Chapman SK et al. Roles of key activesite residues in flavocytochrome P450 BM3. Biochem J 1999;379:371-9
    • (1999) Biochem J , vol.379 , pp. 371-379
    • Noble, M.A.1    Miles, C.S.2    Chapman, S.K.3
  • 57
    • 11544324496 scopus 로고    scopus 로고
    • Enzymatic aspects of isoprenoid chain elongation
    • Ogura K, Koyama T. Enzymatic aspects of isoprenoid chain elongation. Chem Rev 1998;98:1263-76
    • (1998) Chem Rev , vol.98 , pp. 1263-1276
    • Ogura, K.1    Koyama, T.2
  • 58
    • 0032462288 scopus 로고    scopus 로고
    • Effect of oxidative stress on the biosynthesis of 2-C-methyl-D-erythritol-2, 4-cyclopyrophosphate and isoprenoids by several bacterial strains
    • Ostrovsky D, Diomina G, Lysak E et al. Effect of oxidative stress on the biosynthesis of 2-C-methyl-D-erythritol-2, 4-cyclopyrophosphate and isoprenoids by several bacterial strains. Arch Microbiol 1998;171:69-72
    • (1998) Arch Microbiol , vol.171 , pp. 69-72
    • Ostrovsky, D.1    Diomina, G.2    Lysak, E.3
  • 59
    • 80053412686 scopus 로고    scopus 로고
    • Identification and microbial production of a terpene-based advanced biofuel
    • Peralta-yahya PP, Ouellet M, Chan R et al. Identification and microbial production of a terpene-based advanced biofuel. Nat Commun 2011;2:483-8
    • (2011) Nat Commun , vol.2 , pp. 483-488
    • Peralta-yahya, P.P.1    Ouellet, M.2    Chan, R.3
  • 60
    • 84929143779 scopus 로고    scopus 로고
    • Efficient searching and annotation of metabolic networks using chemical similarity
    • Pertusi DA, Stine AE, Broadbelt LJ et al. Efficient searching and annotation of metabolic networks using chemical similarity. Bioinformatics 2015;31:1016-24
    • (2015) Bioinformatics , vol.31 , pp. 1016-1024
    • Pertusi, D.A.1    Stine, A.E.2    Broadbelt, L.J.3
  • 61
    • 33847309176 scopus 로고    scopus 로고
    • Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli
    • Pitera DJ, Paddon CJ, Newman JD et al. Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli. Metab Eng 2007;9:193-207
    • (2007) Metab Eng , vol.9 , pp. 193-207
    • Pitera, D.J.1    Paddon, C.J.2    Newman, J.D.3
  • 62
    • 21244464767 scopus 로고    scopus 로고
    • fldA is an essential gene required in the 2-C-methyl-D-erythritol-4-phosphate pathway for isoprenoid biosynthesis
    • Puan K, Wang H, Dairi T et al. fldA is an essential gene required in the 2-C-methyl-D-erythritol-4-phosphate pathway for isoprenoid biosynthesis. FEBS Lett 2005;579:3802-6
    • (2005) FEBS Lett , vol.579 , pp. 3802-3806
    • Puan, K.1    Wang, H.2    Dairi, T.3
  • 63
    • 77952813340 scopus 로고    scopus 로고
    • Building Fe-S proteins: bacterial strategies
    • Py B, Barras F. Building Fe-S proteins: bacterial strategies. Nat Rev Microbiol 2010;8:436-46
    • (2010) Nat Rev Microbiol , vol.8 , pp. 436-446
    • Py, B.1    Barras, F.2
  • 64
    • 84874687019 scopus 로고    scopus 로고
    • Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
    • Qi LS, Larson MH, Gilbert LA et al. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 2013;152:1173-83
    • (2013) Cell , vol.152 , pp. 1173-1183
    • Qi, L.S.1    Larson, M.H.2    Gilbert, L.A.3
  • 65
    • 79952108014 scopus 로고    scopus 로고
    • Targeted proteomics for metabolic pathway optimization: application to terpene production
    • Redding-johanson AM, Batth TS, Chan R et al. Targeted proteomics for metabolic pathway optimization: application to terpene production. Metab Eng 2011;13:194-203
    • (2011) Metab Eng , vol.13 , pp. 194-203
    • Redding-johanson, A.M.1    Batth, T.S.2    Chan, R.3
  • 66
    • 84942525032 scopus 로고    scopus 로고
    • Improvement of glucaric acid production in E. coli via dynamic control of metabolic fluxes
    • Reizman IMB, Stenger AR, Reisch CR et al. Improvement of glucaric acid production in E. coli via dynamic control of metabolic fluxes. Metab Eng Commun 2015;2:109-16
    • (2015) Metab Eng Commun , vol.2 , pp. 109-116
    • Reizman, I.M.B.1    Stenger, A.R.2    Reisch, C.R.3
  • 67
    • 33645870422 scopus 로고    scopus 로고
    • Production of the antimalarial drug precursor artemisinic acid in engineered yeast
    • Ro DK, Paradise EM, Quellet M et al. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 2006;440:940-3
    • (2006) Nature , vol.440 , pp. 940-943
    • Ro, D.K.1    Paradise, E.M.2    Quellet, M.3
  • 68
    • 0029922877 scopus 로고    scopus 로고
    • Glyceraldehyde 3-phosphate and pyruvate as precursors of isoprenic units in an alternative non-mevalonate pathway for terpenoid biosynthesis
    • Rohmer M, Seemann M, Horbach S et al. Glyceraldehyde 3-phosphate and pyruvate as precursors of isoprenic units in an alternative non-mevalonate pathway for terpenoid biosynthesis. J Am Chem Soc 1996;118:2564-6
    • (1996) J Am Chem Soc , vol.118 , pp. 2564-2566
    • Rohmer, M.1    Seemann, M.2    Horbach, S.3
  • 69
    • 84887227402 scopus 로고    scopus 로고
    • Understanding the function of bacterial and eukaryotic thiolases II by integrating evolutionary and functional approaches
    • Romina A, Soto G, Mozzicafreddo M et al. Understanding the function of bacterial and eukaryotic thiolases II by integrating evolutionary and functional approaches. Gene 2014;533:5-10
    • (2014) Gene , vol.533 , pp. 5-10
    • Romina, A.1    Soto, G.2    Mozzicafreddo, M.3
  • 70
    • 0343129339 scopus 로고
    • The biosynthesis of β-hydroxy-β-methylglutaric acid
    • Rudney H. The biosynthesis of β-hydroxy-β-methylglutaric acid. J Biol Chem 1957;227:363-77
    • (1957) J Biol Chem , vol.227 , pp. 363-377
    • Rudney, H.1
  • 71
    • 85050606865 scopus 로고    scopus 로고
    • Biotechnology of Isoprenoid
    • Schrader J, Bohlmann J (eds.)
    • Schrader J. Biotechnology of Isoprenoids. Schrader J, Bohlmann J (eds.), Switzerland: Springer, 2015, Pages v-vi.
    • (2015) Switzerland: Springer , pp. v-vi
    • Schrader, J.1
  • 72
    • 84982792232 scopus 로고    scopus 로고
    • Dynamic control of the mevalonate pathway expression for improved zeaxanthin production in Escherichia coli and comparative proteome analysis
    • Shen H, Cheng B, Zhang Y et al. Dynamic control of the mevalonate pathway expression for improved zeaxanthin production in Escherichia coli and comparative proteome analysis. Metab Eng 2016;38:180-90
    • (2016) Metab Eng , vol.38 , pp. 180-190
    • Shen, H.1    Cheng, B.2    Zhang, Y.3
  • 73
    • 84902287559 scopus 로고    scopus 로고
    • Production of lycopene by metabolicallyengineered Escherichia coli
    • SunT, Miao L, Li Q et al. Production of lycopene by metabolicallyengineered Escherichia coli. Biotechnol Lett 2014;36:1515-22
    • (2014) Biotechnol Lett , vol.36 , pp. 1515-1522
    • Sun, T.1    Miao, L.2    Li, Q.3
  • 74
    • 84987851200 scopus 로고    scopus 로고
    • Bacterial production of pinene by a laboratory-evolved pinene-synthase
    • Tashiro M, Kiyota H, Kawai-Noma S et al. Bacterial production of pinene by a laboratory-evolved pinene-synthase. ACS Synth Biol 2016;5:1011-20
    • (2016) ACS Synth Biol , vol.5 , pp. 1011-1020
    • Tashiro, M.1    Kiyota, H.2    Kawai-Noma, S.3
  • 75
    • 85011866771 scopus 로고    scopus 로고
    • Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae
    • Tippmann S, Ferreira R, Siewers V et al. Effects of acetoacetyl-CoA synthase expression on production of farnesene in Saccharomyces cerevisiae. J Ind Microb Biot 2017;44: 911-22
    • (2017) J Ind Microb Biot , vol.44 , pp. 911-922
    • Tippmann, S.1    Ferreira, R.2    Siewers, V.3
  • 76
    • 84959133257 scopus 로고    scopus 로고
    • Engineering cell factories for producing building block chemicals for bio-polymer synthesis
    • Tsuge Y, Kawaguchi H, Sasaki K et al. Engineering cell factories for producing building block chemicals for bio-polymer synthesis. Microb Cell Fact 2016;15:1-12
    • (2016) Microb Cell Fact , vol.15 , pp. 1-12
    • Tsuge, Y.1    Kawaguchi, H.2    Sasaki, K.3
  • 77
    • 84879142653 scopus 로고    scopus 로고
    • High-Level production of Amorpha-4, 11-Diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli
    • Tsuruta H, Paddon CJ, Eng D et al. High-Level production of Amorpha-4, 11-Diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. PLoS One 2009;4:e4489
    • (2009) PLoS One , vol.4
    • Tsuruta, H.1    Paddon, C.J.2    Eng, D.3
  • 78
    • 85002523976 scopus 로고    scopus 로고
    • 13C-metabolic flux analysis for mevalonate-producing strain of Escherichia coli
    • Wada K, Toya Y, Banno S et al. 13C-metabolic flux analysis for mevalonate-producing strain of Escherichia coli. J Biosci Bioeng 2017;123:177-82
    • (2017) J Biosci Bioeng , vol.123 , pp. 177-182
    • Wada, K.1    Toya, Y.2    Banno, S.3
  • 79
    • 84989898744 scopus 로고    scopus 로고
    • Farnesol production in Escherichia coli through the construction of a farnesol biosynthesis pathway-application of PgpB and YbjG phosphatases
    • Wang C, Park JE, Choi ES et al. Farnesol production in Escherichia coli through the construction of a farnesol biosynthesis pathway-application of PgpB and YbjG phosphatases. Biotechnol J 2016;11:1291-7
    • (2016) Biotechnol J , vol.11 , pp. 1291-1297
    • Wang, C.1    Park, J.E.2    Choi, E.S.3
  • 80
    • 83055173108 scopus 로고    scopus 로고
    • Overexpression of Brassica juncea wild-type andmutant HMG-CoA synthase 1 in Arabidopsis up-regulates genes in sterol biosynthesis and enhances sterol production and stress tolerance
    • Wang H, Nagegowda DA, Rawat R et al. Overexpression of Brassica juncea wild-type andmutant HMG-CoA synthase 1 in Arabidopsis up-regulates genes in sterol biosynthesis and enhances sterol production and stress tolerance. Plant Biotechnol J 2012;10:31-42
    • (2012) Plant Biotechnol J , vol.10 , pp. 31-42
    • Wang, H.1    Nagegowda, D.A.2    Rawat, R.3
  • 81
    • 84911430915 scopus 로고    scopus 로고
    • A kinetic-based approach to understanding heterologous mevalonate pathway function in
    • Weaver LJ, Sousa MML, Wang G et al. A kinetic-based approach to understanding heterologous mevalonate pathway function in. Biotechnol Bioeng 2015;112:111-9
    • (2015) Biotechnol Bioeng , vol.112 , pp. 111-119
    • Weaver, L.J.1    Sousa, M.M.L.2    Wang, G.3
  • 82
    • 84905395433 scopus 로고    scopus 로고
    • Engineering the productivity of recombinant Escherichia coli for limonene formation from glycerol in minimal media
    • Willrodt C, David C, Cornelissen S et al. Engineering the productivity of recombinant Escherichia coli for limonene formation from glycerol in minimal media. Biotechnol J 2014;9: 1000-12
    • (2014) Biotechnol J , vol.9 , pp. 1000-1012
    • Willrodt, C.1    David, C.2    Cornelissen, S.3
  • 83
    • 67651233275 scopus 로고    scopus 로고
    • Revisiting the IspH catalytic system in the deoxyxylulose phosphate pathway: achieving high activity
    • Xiao Y, Chu L, Sanakis Y et al. Revisiting the IspH catalytic system in the deoxyxylulose phosphate pathway: achieving high activity. J Am Chem Soc 2009;131:9931-3
    • (2009) J Am Chem Soc , vol.131 , pp. 9931-9933
    • Xiao, Y.1    Chu, L.2    Sanakis, Y.3
  • 84
    • 85012838041 scopus 로고    scopus 로고
    • Improving metabolic pathway efficiency by statistical model-based multivariate regulatory metabolic engineering
    • Xu P, Rizzoni EA, Sul SY et al. Improving metabolic pathway efficiency by statistical model-based multivariate regulatory metabolic engineering. ACS Synth Biol 2017;6: 148-58
    • (2017) ACS Synth Biol , vol.6 , pp. 148-158
    • Xu, P.1    Rizzoni, E.A.2    Sul, S.Y.3
  • 85
    • 84904418029 scopus 로고    scopus 로고
    • PredictProtein-An open resource for online prediction of protein structural and functional features
    • Yachdav G, Kloppmann E, Kajan L et al. PredictProtein-An open resource for online prediction of protein structural and functional features. Nucleic Acids Res 2014;42: W337-43
    • (2014) Nucleic Acids Res , vol.42 , pp. W337-W343
    • Yachdav, G.1    Kloppmann, E.2    Kajan, L.3
  • 86
    • 84859776222 scopus 로고    scopus 로고
    • The future of metabolic engineering and synthetic biology: towards a systematic practice
    • Yadav VG, De Mey M, Giaw C et al. The future of metabolic engineering and synthetic biology: towards a systematic practice. Metab Eng 2012;14:233-41
    • (2012) Metab Eng , vol.14 , pp. 233-241
    • Yadav, V.G.1    De Mey, M.2    Giaw, C.3
  • 87
    • 84964313167 scopus 로고    scopus 로고
    • Biosynthesis of β-carotene in engineered E. coli using the MEP and MVA pathways
    • Yang J, Guo L. Biosynthesis of β-carotene in engineered E. coli using the MEP and MVA pathways. Microb Cell Fact 2014;13:1-11
    • (2014) Microb Cell Fact , vol.13 , pp. 1-11
    • Yang, J.1    Guo, L.2
  • 88
  • 89
    • 79959374585 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for direct production of 1, 4-butanediol
    • Yim H, Haselbeck R, Niu W et al. Metabolic engineering of Escherichia coli for direct production of 1, 4-butanediol. Nat Chem Biol 2011;7:445-52
    • (2011) Nat Chem Biol , vol.7 , pp. 445-452
    • Yim, H.1    Haselbeck, R.2    Niu, W.3
  • 90
    • 62849084758 scopus 로고    scopus 로고
    • Combinatorial expression of bacterial wholemevalonate pathway for the production of β-carotene in E. coli
    • Yoon S, Lee S, Das A et al. Combinatorial expression of bacterial wholemevalonate pathway for the production of β-carotene in E. coli. J Biotechnol 2009;140:218-26
    • (2009) J Biotechnol , vol.140 , pp. 218-226
    • Yoon, S.1    Lee, S.2    Das, A.3
  • 91
    • 85021431830 scopus 로고    scopus 로고
    • Utilization of biodiesel by-product as substrate for high-production of B-farnesene via relatively balanced mevalonate pathway in Escherichia coli
    • You S, Yin Q, Zhang J et al. Utilization of biodiesel by-product as substrate for high-production of B-farnesene via relatively balanced mevalonate pathway in Escherichia coli. Bioresource Technol 2017;243:228-36
    • (2017) Bioresource Technol , vol.243 , pp. 228-236
    • You, S.1    Yin, Q.2    Zhang, J.3
  • 92
    • 84885038885 scopus 로고    scopus 로고
    • Combining genotype improvement and statistical media optimization for isoprenoid production in E. coli
    • Zhang C, Chen X, Zou R et al. Combining genotype improvement and statistical media optimization for isoprenoid production in E. coli. PLoS One 2013;8, DOI: 10.1371/journal.pone.0075164
    • (2013) PLoS One , pp. 8
    • Zhang, C.1    Chen, X.2    Zou, R.3
  • 93
    • 84875670791 scopus 로고    scopus 로고
    • Engineering central metabolic modules of Escherichia coli for improving beta-carotene production
    • Zhao J, Li Q, Sun T et al. Engineering central metabolic modules of Escherichia coli for improving beta-carotene production. Metab Eng 2013;17:42-50
    • (2013) Metab Eng , vol.17 , pp. 42-50
    • Zhao, J.1    Li, Q.2    Sun, T.3
  • 94
    • 84910088212 scopus 로고    scopus 로고
    • Geranyl diphosphate synthase: an important regulation point in balancing a recombinant monoterpene pathway in Escherichia coli
    • Zhou J, Wang C, Yang L et al. Geranyl diphosphate synthase: an important regulation point in balancing a recombinant monoterpene pathway in Escherichia coli. Enzyme Microb Tech 2015a;68:50-5
    • (2015) Enzyme Microb Tech , vol.68 , pp. 50-55
    • Zhou, J.1    Wang, C.2    Yang, L.3
  • 95
    • 84926646130 scopus 로고    scopus 로고
    • Distributing a metabolic pathway among a microbial consortium enhances production of natural products
    • Zhou K, Qiao K, Edgar S et al. Distributing a metabolic pathway among a microbial consortium enhances production of natural products. Nat Biotechnol 2015b;33:377-83
    • (2015) Nat Biotechnol , vol.33 , pp. 377-383
    • Zhou, K.1    Qiao, K.2    Edgar, S.3
  • 96
    • 84868318317 scopus 로고    scopus 로고
    • Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production
    • Zhou K, Zou R, Stephanopoulos G et al. Metabolite profiling identified methylerythritol cyclodiphosphate efflux as a limiting step in microbial isoprenoid production. PLoS One 2012;7:e47513
    • (2012) PLoS One , vol.7
    • Zhou, K.1    Zou, R.2    Stephanopoulos, G.3
  • 97
    • 84887278671 scopus 로고    scopus 로고
    • Lycopene production in recombinant strains of Escherichia coli is improved by knockout of the central carbon metabolism gene coding for glucose-6-phosphate dehydrogenase
    • Zhou Y, Nambou K, Wei L et al. Lycopene production in recombinant strains of Escherichia coli is improved by knockout of the central carbon metabolism gene coding for glucose-6-phosphate dehydrogenase. Biotechnol Lett 2013;35:2137-45
    • (2013) Biotechnol Lett , vol.35 , pp. 2137-2145
    • Zhou, Y.1    Nambou, K.2    Wei, L.3
  • 98
    • 84901617508 scopus 로고    scopus 로고
    • In vitro reconstitution ofmevalonate pathway and targeted engineering of farnesene overproduction in Escherichia coli
    • Zhu F, Zhong X, Hu M et al. In vitro reconstitution ofmevalonate pathway and targeted engineering of farnesene overproduction in Escherichia coli. Biotechnol Bioeng 2014;111:1396-405
    • (2014) Biotechnol Bioeng , vol.111 , pp. 1396-1405
    • Zhu, F.1    Zhong, X.2    Hu, M.3


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