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Volumn 28, Issue 1, 2012, Pages 292-296

Improved E. coli erythromycin a production through the application of metabolic and bioprocess engineering

Author keywords

E. coli; Erythromycin A; Heterologous biosynthesis; Metabolic and process engineering

Indexed keywords

BATCH BIOREACTORS; BIOPROCESS ENGINEERING; BIOSYNTHETIC PATHWAY; CARBON FLOW; DEOXYSUGAR; E. COLI; ERYTHROMYCIN A; GLYCOSYL TRANSFERASE; HETEROLOGOUS PRODUCTION;

EID: 84856576230     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.702     Document Type: Article
Times cited : (19)

References (25)
  • 1
    • 14544294545 scopus 로고    scopus 로고
    • Bioactive microbial metabolites
    • Berdy J. Bioactive microbial metabolites. J Antibiot (Tokyo). 2005; 58: 1-26.
    • (2005) J Antibiot (Tokyo). , vol.58 , pp. 1-26
    • Berdy, J.1
  • 2
    • 33845708150 scopus 로고    scopus 로고
    • New antibiotics from bacterial natural products
    • Clardy J, Fischbach MA, Walsh CT. New antibiotics from bacterial natural products. Nat Biotechnol. 2006; 24: 1541-1550.
    • (2006) Nat Biotechnol. , vol.24 , pp. 1541-1550
    • Clardy, J.1    Fischbach, M.A.2    Walsh, C.T.3
  • 3
    • 33745024719 scopus 로고    scopus 로고
    • From natural products discovery to commercialization: a success story
    • Demain AL. From natural products discovery to commercialization: a success story. J Ind Microbiol Biotechnol. 2006; 33: 486-495.
    • (2006) J Ind Microbiol Biotechnol. , vol.33 , pp. 486-495
    • Demain, A.L.1
  • 4
    • 14944383798 scopus 로고    scopus 로고
    • The evolving role of natural products in drug discovery
    • Koehn FE, Carter GT. The evolving role of natural products in drug discovery. Nat Rev Drug Discov. 2005; 4: 206-220.
    • (2005) Nat Rev Drug Discov. , vol.4 , pp. 206-220
    • Koehn, F.E.1    Carter, G.T.2
  • 5
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • Newman DJ, Cragg GM. Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007; 70: 461-477.
    • (2007) J Nat Prod. , vol.70 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 6
    • 78649391538 scopus 로고    scopus 로고
    • Methods and options for the heterologous production of complex natural products
    • Zhang H, Boghigian BA, Armando J, Pfeifer BA. Methods and options for the heterologous production of complex natural products. Nat Prod Rep. 17 2011; 28: 125-151.
    • (2011) Nat Prod Rep. 17 , vol.28 , pp. 125-151
    • Zhang, H.1    Boghigian, B.A.2    Armando, J.3    Pfeifer, B.A.4
  • 8
    • 0013547013 scopus 로고
    • The antibacterial action of erythromycin
    • Haight TH, Finland M. The antibacterial action of erythromycin. Proc Soc Exp Biol Med. 1952; 81: 175-183.
    • (1952) Proc Soc Exp Biol Med. , vol.81 , pp. 175-183
    • Haight, T.H.1    Finland, M.2
  • 9
    • 0031665125 scopus 로고    scopus 로고
    • Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vitreoscilla haemoglobin gene (vhb)
    • Brunker P, Minas W, Kallio PT, Bailey JE. Genetic engineering of an industrial strain of Saccharopolyspora erythraea for stable expression of the Vitreoscilla haemoglobin gene (vhb). Microbiology. 1998; 144 ( Part 9): 2441-2448.
    • (1998) Microbiology. , vol.144 , Issue.PART 9 , pp. 2441-2448
    • Brunker, P.1    Minas, W.2    Kallio, P.T.3    Bailey, J.E.4
  • 10
    • 34547487372 scopus 로고    scopus 로고
    • Improved production of erythromycin A by expression of a heterologous gene encoding S-adenosylmethionine synthetase
    • Wang Y, Chu J, Zhuang Y, Zhang L, Zhang S. Improved production of erythromycin A by expression of a heterologous gene encoding S-adenosylmethionine synthetase. Appl Microbiol Biotechnol. 2007; 75: 837-842.
    • (2007) Appl Microbiol Biotechnol. , vol.75 , pp. 837-842
    • Wang, Y.1    Chu, J.2    Zhuang, Y.3    Zhang, L.4    Zhang, S.5
  • 11
    • 3142783726 scopus 로고    scopus 로고
    • A multi-scale study of industrial fermentation processes and their optimization
    • Zhang S, Chu J, Zhuang Y. A multi-scale study of industrial fermentation processes and their optimization. Adv Biochem Eng Biotechnol. 2004; 87: 97-150.
    • (2004) Adv Biochem Eng Biotechnol. , vol.87 , pp. 97-150
    • Zhang, S.1    Chu, J.2    Zhuang, Y.3
  • 13
    • 0032128237 scopus 로고    scopus 로고
    • Improved erythromycin production in a genetically engineered industrial strain of Saccharopolyspora erythraea
    • Minas W, Brunker P, Kallio PT, Bailey JE. Improved erythromycin production in a genetically engineered industrial strain of Saccharopolyspora erythraea. Biotechnol Prog. 1998; 14: 561-566.
    • (1998) Biotechnol Prog. , vol.14 , pp. 561-566
    • Minas, W.1    Brunker, P.2    Kallio, P.T.3    Bailey, J.E.4
  • 14
    • 40849100148 scopus 로고    scopus 로고
    • Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea fermentation
    • Chen Y, Deng W, Wu J, Qian J, Chu J, Zhuang Y, Zhang S, Liu W. Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea fermentation. Appl Environ Microbiol. 2008; 74: 1820-1828.
    • (2008) Appl Environ Microbiol. , vol.74 , pp. 1820-1828
    • Chen, Y.1    Deng, W.2    Wu, J.3    Qian, J.4    Chu, J.5    Zhuang, Y.6    Zhang, S.7    Liu, W.8
  • 15
    • 63449101169 scopus 로고    scopus 로고
    • Enhancement of erythromycin A production with feeding available nitrogen sources in erythromycin biosynthesis phase
    • Zou X, Hang HF, Chu J, Zhuang YP, Zhang SL. Enhancement of erythromycin A production with feeding available nitrogen sources in erythromycin biosynthesis phase. Bioresour Technol. 2009; 100: 3358-3365.
    • (2009) Bioresour Technol. , vol.100 , pp. 3358-3365
    • Zou, X.1    Hang, H.F.2    Chu, J.3    Zhuang, Y.P.4    Zhang, S.L.5
  • 16
    • 0035793858 scopus 로고    scopus 로고
    • Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli
    • Pfeifer BA, Admiraal SJ, Gramajo H, Cane DE, Khosla C. Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli. Science. 2001; 291: 1790-1792.
    • (2001) Science. , vol.291 , pp. 1790-1792
    • Pfeifer, B.A.1    Admiraal, S.J.2    Gramajo, H.3    Cane, D.E.4    Khosla, C.5
  • 17
  • 18
    • 33847000219 scopus 로고    scopus 로고
    • Bioassay-guided evolution of glycosylated macrolide antibiotics in Escherichia coli
    • Lee HY, Khosla C. Bioassay-guided evolution of glycosylated macrolide antibiotics in Escherichia coli. PLoS Biol. 2007; 5: e45.
    • (2007) PLoS Biol. , vol.5
    • Lee, H.Y.1    Khosla, C.2
  • 19
    • 78649386219 scopus 로고    scopus 로고
    • Complete biosynthesis of erythromycin A and designed analogs using E. coli as a heterologous host
    • Zhang H, Wang Y, Wu J, Skalina K, Pfeifer BA. Complete biosynthesis of erythromycin A and designed analogs using E. coli as a heterologous host. Chem Biol. 2010; 17: 1232-1240.
    • (2010) Chem Biol. , vol.17 , pp. 1232-1240
    • Zhang, H.1    Wang, Y.2    Wu, J.3    Skalina, K.4    Pfeifer, B.A.5
  • 20
    • 74849084621 scopus 로고    scopus 로고
    • Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production in Escherichia coli
    • Zhang H, Boghigian BA, Pfeifer BA. Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production in Escherichia coli. Biotechnol Bioeng. 2010; 105: 567-573.
    • (2010) Biotechnol Bioeng. , vol.105 , pp. 567-573
    • Zhang, H.1    Boghigian, B.A.2    Pfeifer, B.A.3
  • 21
    • 0034712657 scopus 로고    scopus 로고
    • Discovering new enzymes and metabolic pathways: conversion of succinate to propionate by Escherichia coli
    • Haller T, Buckel T, Retey J, Gerlt JA. Discovering new enzymes and metabolic pathways: conversion of succinate to propionate by Escherichia coli. Biochemistry. 2000; 39: 4622-4629.
    • (2000) Biochemistry. , vol.39 , pp. 4622-4629
    • Haller, T.1    Buckel, T.2    Retey, J.3    Gerlt, J.A.4
  • 22
    • 0030831132 scopus 로고    scopus 로고
    • Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production
    • Summers RG, Donadio S, Staver MJ, Wendt-Pienkowski E, Hutchinson CR, Katz L. Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production. Microbiology. 1997; 143 ( Part 10): 3251-3262.
    • (1997) Microbiology. , vol.143 , Issue.PART 10 , pp. 3251-3262
    • Summers, R.G.1    Donadio, S.2    Staver, M.J.3    Wendt-Pienkowski, E.4    Hutchinson, C.R.5    Katz, L.6
  • 23
    • 64049100642 scopus 로고    scopus 로고
    • Metabolically engineered Escherichia coli for efficient production of glycosylated natural products
    • Peiru SR, Rodriguez E, Menzella HG, Carney JR, Gramajo H. Metabolically engineered Escherichia coli for efficient production of glycosylated natural products. Microb Biotechnol. 2008; 1: 476-486.
    • (2008) Microb Biotechnol. , vol.1 , pp. 476-486
    • Peiru, S.R.1    Rodriguez, E.2    Menzella, H.G.3    Carney, J.R.4    Gramajo, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.