Synthetic protein scaffolds provide modular control over metabolic flux

Nature Biotechnology

Volumn 27, Issue 8, 2009, Pages 753-759

  Dueber, John E ^a,b   Wu, Gabriel C ^a,b   Malmirchegini, G Reza ^a   Moon, Tae Seok ^c,d   Petzold, Christopher J ^e,f   Ullal, Adeeti V ^f   Prather, Kristala L J ^c,d   Keasling, Jay D ^a,b,e,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d JOINT BIOENERGY INSTITUTE   (United States)

^e University of California at Berkeley   (United States)

^f University of California   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHETIC ENZYMES; EFFECTIVE CONCENTRATION; GLUCARIC ACID; INTERACTION DOMAIN; METABOLIC ENZYMES; METABOLIC FLUX; METABOLIC PATHWAYS; MEVALONATE; MODULAR CONTROL; PEPTIDE LIGAND; REGULATORY MECHANISM; SIGNALING PROTEINS; SYNTHETIC PROTEIN;

AMINES; CATALYSTS; ENZYMES; SCAFFOLDS; STOICHIOMETRY;

METABOLISM;

LIGAND; PEPTIDE; PROTEIN; SACCHARIC ACID;

ARTICLE; COMPLEX FORMATION; METABOLIC ENGINEERING; METAZOON; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STOICHIOMETRY;

ANIMALS; BIOCATALYSIS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GLUCARIC ACID; METABOLIC NETWORKS AND PATHWAYS; MEVALONIC ACID; MICE; PROTEIN BINDING; PROTEIN ENGINEERING; RATS; TITRIMETRY;

METAZOA;

EID: 68449088806     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.1557     Document Type: Article

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