Synergy between 13C-metabolic flux analysis and flux balance analysis for understanding metabolic adaption to anaerobiosis in E. coli

Metabolic Engineering

Volumn 13, Issue 1, 2011, Pages 38-48

  Chen, Xuewen ^a   Alonso, Ana P ^a   Allen, Doug K ^b   Reed, Jennifer L ^c   Shachar Hill, Yair ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

E. coli; Flux balance analysis; Formate hydrogen lyase; Incomplete TCA cycle; Maintenance ATP utilization; Metabolic flux analysis

Indexed keywords

E. COLI; FLUX BALANCE ANALYSIS; FORMATE HYDROGEN LYASE; METABOLIC FLUX ANALYSIS; TCA CYCLE;

CELL CULTURE; ECOLOGY; ESCHERICHIA COLI; GENES; GLUCOSE; HYDROGEN; MAINTENANCE; OXYGEN; PHOSPHORYLATION; PHYSIOLOGY;

METABOLISM;

ADENOSINE TRIPHOSPHATE; CARBON 13; GLUCOSE; OXYGEN; PROTON; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

AEROBIC METABOLISM; ANAEROBIC GROWTH; ANAEROBIC METABOLISM; ARTICLE; BACTERIAL CELL; BACTERIAL GENOME; BACTERIAL METABOLISM; BACTERIUM CULTURE; CARBON METABOLISM; CONTROLLED STUDY; ENERGY CONSUMPTION; ESCHERICHIA COLI; FERMENTATION; FLUX BALANCE ANALYSIS; GLUCOSE UTILIZATION; METABOLIC BALANCE; METABOLIC FLUX ANALYSIS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; WILD TYPE;

ADAPTATION, PHYSIOLOGICAL; ADENOSINE TRIPHOSPHATE; ANAEROBIOSIS; CARBON ISOTOPES; CITRIC ACID CYCLE; COMPUTER SIMULATION; ENERGY TRANSFER; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MAGNETIC RESONANCE SPECTROSCOPY; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; OXYGEN;

ESCHERICHIA COLI;

EID: 78650574197     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2010.11.004     Document Type: Article

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