Repurposing type III polyketide synthase as a malonyl- CoA biosensor for metabolic engineering in bacteria

Proceedings of the National Academy of Sciences of the United States of America

Volumn 115, Issue 40, 2018, Pages 9835-9844

  Yang, Dongsoo ^a,b   Kim, Won Jun ^a,b   Yoo, Seung Min ^a,b   Choi, Jong Hyun ^c   Ha, Shin Hee ^a   Lee, Mun Hee ^a,b   Lee, Sang Yup ^a,b,d  

^a BioProcess Engineering Research Center   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Jeonbuk Branch Institute   (South Korea)

^d Chalmers University of Technology   (Denmark)

Author keywords

Biosensor; Malonyl coa; Metabolic engineering; Natural products; Polyketide synthase

Indexed keywords

6 METHYLSALICYLIC ACID; ALOESONE; MALONYL COENZYME A; NARINGENIN; POLYKETIDE; POLYKETIDE SYNTHASE; RESVERATROL; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; RPPA PROTEIN, SYNECHOCYSTIS;

ARTICLE; BACTERIAL STRAIN; COLORIMETRY; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; ESCHERICHIA COLI; GENE KNOCKDOWN; GENE LIBRARY; GENE TARGETING; GENETIC ENGINEERING; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS PUTIDA; SYNTHESIS; ENZYMOLOGY; GENETIC PROCEDURES; GENETICS; METABOLISM; PROCEDURES;

BACTERIAL PROTEINS; BIOSENSING TECHNIQUES; CORYNEBACTERIUM GLUTAMICUM; ESCHERICHIA COLI; MALONYL COENZYME A; METABOLIC ENGINEERING; POLYKETIDE SYNTHASES; PSEUDOMONAS PUTIDA;

EID: 85054360865     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1808567115     Document Type: Article

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