-
1
-
-
84940111165
-
Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals
-
Jullesson, D., David, F., Pfleger, B., and Nielsen, J. (2015) Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals Biotechnol. Adv. 33, 1395 10.1016/j.biotechadv.2015.02.011
-
(2015)
Biotechnol. Adv.
, vol.33
, pp. 1395
-
-
Jullesson, D.1
David, F.2
Pfleger, B.3
Nielsen, J.4
-
2
-
-
17444430819
-
Total synthesis of alternariol
-
Koch, K., Podlech, J., Pfeiffer, E., and Metzler, M. (2005) Total synthesis of alternariol J. Org. Chem. 70, 3275-3276 10.1021/jo050075r
-
(2005)
J. Org. Chem.
, vol.70
, pp. 3275-3276
-
-
Koch, K.1
Podlech, J.2
Pfeiffer, E.3
Metzler, M.4
-
3
-
-
84922212497
-
When plants produce not enough or at all: Metabolic engineering of flavonoids in microbial hosts
-
Trantas, E. A., Koffas, M., Xu, P., and Ververidis, F. (2015) When plants produce not enough or at all: metabolic engineering of flavonoids in microbial hosts Front. Plant Sci. 10.3389/fpls.2015.00007
-
(2015)
Front. Plant Sci.
-
-
Trantas, E.A.1
Koffas, M.2
Xu, P.3
Ververidis, F.4
-
4
-
-
84920880193
-
A review of metabolic and enzymatic engineering strategies for designing and optimizing performance of microbial cell factories
-
Fisher, A. K., Freedman, B. G., Bevan, D. R., and Senger, R. S. (2014) A review of metabolic and enzymatic engineering strategies for designing and optimizing performance of microbial cell factories Comput. Struct. Biotechnol. J. 11, 91-99 10.1016/j.csbj.2014.08.010
-
(2014)
Comput. Struct. Biotechnol. J.
, vol.11
, pp. 91-99
-
-
Fisher, A.K.1
Freedman, B.G.2
Bevan, D.R.3
Senger, R.S.4
-
5
-
-
84923809316
-
Biorefineries for the production of top building block chemicals and their derivatives
-
Choi, S., Song, C. W., Shin, J. H., and Lee, S. Y. (2015) Biorefineries for the production of top building block chemicals and their derivatives Metab. Eng. 28, 223-239 10.1016/j.ymben.2014.12.007
-
(2015)
Metab. Eng.
, vol.28
, pp. 223-239
-
-
Choi, S.1
Song, C.W.2
Shin, J.H.3
Lee, S.Y.4
-
6
-
-
78649716727
-
Manufacturing molecules through metabolic engineering
-
Keasling, J. D. (2010) Manufacturing molecules through metabolic engineering Science (Washington, DC, U. S.) 330, 1355-8 10.1126/science.1193990
-
(2010)
Science (Washington, DC, U. S.)
, vol.330
, pp. 1355-1358
-
-
Keasling, J.D.1
-
7
-
-
0034496492
-
Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria
-
Jones, K. L., Kim, S.-W., and Keasling, J. (2000) Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria Metab. Eng. 2, 328-338 10.1006/mben.2000.0161
-
(2000)
Metab. Eng.
, vol.2
, pp. 328-338
-
-
Jones, K.L.1
Kim, S.-W.2
Keasling, J.3
-
8
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito, R. R. (2000) Aggresomes, inclusion bodies and protein aggregation Trends Cell Biol. 10, 524-530 10.1016/S0962-8924(00)01852-3
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 524-530
-
-
Kopito, R.R.1
-
9
-
-
84897406062
-
Predictive combinatorial design of mRNA translation initiation regions for systematic optimization of gene expression levels
-
Seo, S. W., Yang, J.-S., Cho, H.-S., Yang, J., Kim, S. C., Park, J. M., Kim, S., and Jung, G. Y. (2014) Predictive combinatorial design of mRNA translation initiation regions for systematic optimization of gene expression levels Sci. Rep. 10.1038/srep04515
-
(2014)
Sci. Rep.
-
-
Seo, S.W.1
Yang, J.-S.2
Cho, H.-S.3
Yang, J.4
Kim, S.C.5
Park, J.M.6
Kim, S.7
Jung, G.Y.8
-
10
-
-
0037677435
-
Metabolic load of recombinant protein production: Inhibition of cellular capacities for glucose uptake and respiration after induction of a heterologous gene in Escherichia coli
-
Neubauer, P., Lin, H. Y., and Mathiszik, B. (2003) Metabolic load of recombinant protein production: inhibition of cellular capacities for glucose uptake and respiration after induction of a heterologous gene in Escherichia coli Biotechnol. Bioeng. 83, 53-64 10.1002/bit.10645
-
(2003)
Biotechnol. Bioeng.
, vol.83
, pp. 53-64
-
-
Neubauer, P.1
Lin, H.Y.2
Mathiszik, B.3
-
11
-
-
33847309176
-
Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli
-
Pitera, D. J., Paddon, C. J., Newman, J. D., and Keasling, J. D. (2007) Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli Metab. Eng. 9, 193-207 10.1016/j.ymben.2006.11.002
-
(2007)
Metab. Eng.
, vol.9
, pp. 193-207
-
-
Pitera, D.J.1
Paddon, C.J.2
Newman, J.D.3
Keasling, J.D.4
-
12
-
-
34547471980
-
Construction and model-based analysis of a promoter library for E. Coli: An indispensable tool for metabolic engineering
-
De Mey, M., Maertens, J., Lequeux, G. J., Soetaert, W. K., and Vandamme, E. J. (2007) Construction and model-based analysis of a promoter library for E. coli: an indispensable tool for metabolic engineering BMC Biotechnol. 7, 34 10.1186/1472-6750-7-34
-
(2007)
BMC Biotechnol.
, vol.7
, pp. 34
-
-
De Mey, M.1
Maertens, J.2
Lequeux, G.J.3
Soetaert, W.K.4
Vandamme, E.J.5
-
13
-
-
77952310558
-
Promoter knock-in: A novel rational method for the fine tuning of genes
-
De Mey, M., Maertens, J., Boogmans, S., Soetaert, W. K., Vandamme, E. J., Cunin, R., and Foulquié-Moreno, M. R. (2010) Promoter knock-in: a novel rational method for the fine tuning of genes BMC Biotechnol. 10, 26 10.1186/1472-6750-10-26
-
(2010)
BMC Biotechnol.
, vol.10
, pp. 26
-
-
De Mey, M.1
Maertens, J.2
Boogmans, S.3
Soetaert, W.K.4
Vandamme, E.J.5
Cunin, R.6
Foulquié-Moreno, M.R.7
-
14
-
-
84875720517
-
Precise and reliable gene expression via standard transcription and translation initiation element
-
Mutalik, V. K., Guimaraes, J. C., Cambray, G., Lam, C., Christoffersen, M. J., Mai, Q.-A., Tran, A. B., Paull, M., Keasling, J. D., Arkin, A. P., and Endy, D. (2013) Precise and reliable gene expression via standard transcription and translation initiation element Nat. Methods 10, 1-42 10.1038/nmeth.2404
-
(2013)
Nat. Methods
, vol.10
, pp. 1-42
-
-
Mutalik, V.K.1
Guimaraes, J.C.2
Cambray, G.3
Lam, C.4
Christoffersen, M.J.5
Mai, Q.-A.6
Tran, A.B.7
Paull, M.8
Keasling, J.D.9
Arkin, A.P.10
Endy, D.11
-
15
-
-
70349964350
-
Automated design of synthetic ribosome binding sites to control protein expression
-
Salis, H. M., Mirsky, E. A., and Voigt, C. a. (2009) Automated design of synthetic ribosome binding sites to control protein expression Nat. Biotechnol. 27, 946-50 10.1038/nbt.1568
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 946-950
-
-
Salis, H.M.1
Mirsky, E.A.2
Voigt, A.C.3
-
16
-
-
77956371200
-
Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control
-
Leonard, E., Ajikumar, P. K., Thayer, K., Xiao, W.-H., Mo, J. D., Tidor, B., Stephanopoulos, G., and Prather, K. L. J. (2010) Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control Proc. Natl. Acad. Sci. U. S. A. 107, 13654-9 10.1073/pnas.1006138107
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 13654-13659
-
-
Leonard, E.1
Ajikumar, P.K.2
Thayer, K.3
Xiao, W.-H.4
Mo, J.D.5
Tidor, B.6
Stephanopoulos, G.7
Prather, K.L.J.8
-
17
-
-
67349270900
-
Enzymatic assembly of DNA molecules up to several hundred kilobases
-
III C.A.H.
-
Gibson, D. G., Young, L., Chuang, R.-y. Y., Venter, J. C., Iii, C. A. H., Smith, H. O., and America, N. (2009) Enzymatic assembly of DNA molecules up to several hundred kilobases Nat. Methods 6, 12-16 10.1038/nmeth.1318
-
(2009)
Nat. Methods
, vol.6
, pp. 12-16
-
-
Gibson, D.G.1
Young, L.2
Chuang R, Y.-Y.3
Venter, J.C.4
Smith, H.O.5
America, N.6
-
18
-
-
56649114274
-
A one pot, one step, precision cloning method with high throughput capability
-
Engler, C., Kandzia, R., and Marillonnet, S. (2008) A one pot, one step, precision cloning method with high throughput capability PLoS One 3, e3647 10.1371/journal.pone.0003647
-
(2008)
PLoS One
, vol.3
, pp. e3647
-
-
Engler, C.1
Kandzia, R.2
Marillonnet, S.3
-
19
-
-
84921517479
-
Functional optimization of gene clusters by combinatorial design and assembly
-
Smanski, M. J., Bhatia, S., Zhao, D., Park, Y., Woodruff, L. B. a., Giannoukos, G., Ciulla, D., Busby, M., Calderon, J., Nicol, R., Gordon, D. B., Densmore, D., and Voigt, C. a. (2014) Functional optimization of gene clusters by combinatorial design and assembly Nat. Biotechnol. 32, 1241 10.1038/nbt.3063
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 1241
-
-
Smanski, M.J.1
Bhatia, S.2
Zhao, D.3
Park, Y.4
Woodruff, A.B.L.5
Giannoukos, G.6
Ciulla, D.7
Busby, M.8
Calderon, J.9
Nicol, R.10
Gordon, D.B.11
Densmore, D.12
Voigt, A.C.13
-
20
-
-
79951997641
-
A modular cloning system for standardized assembly of multigene constructs
-
Weber, E., Engler, C., Gruetzner, R., Werner, S., and Marillonnet, S. (2011) A modular cloning system for standardized assembly of multigene constructs PLoS One 6, e16765 10.1371/journal.pone.0016765
-
(2011)
PLoS One
, vol.6
, pp. e16765
-
-
Weber, E.1
Engler, C.2
Gruetzner, R.3
Werner, S.4
Marillonnet, S.5
-
21
-
-
79960051013
-
GoldenBraid: An iterative cloning system for standardized assembly of reusable genetic modules
-
Sarrion-Perdigones, A., Falconi, E. E., Zandalinas, S. I., Juárez, P., Fernández-del Carmen, A., Granell, A., and Orzaez, D. (2011) GoldenBraid: an iterative cloning system for standardized assembly of reusable genetic modules PLoS One 6, e21622 10.1371/journal.pone.0021622
-
(2011)
PLoS One
, vol.6
, pp. e21622
-
-
Sarrion-Perdigones, A.1
Falconi, E.E.2
Zandalinas, S.I.3
Juárez, P.4
Fernández-Del Carmen, A.5
Granell, A.6
Orzaez, D.7
-
22
-
-
79951773902
-
Single-step linker-based combinatorial assembly of promoter and gene cassettes for pathway engineering
-
Ramon, A. and Smith, H. O. (2011) Single-step linker-based combinatorial assembly of promoter and gene cassettes for pathway engineering Biotechnol. Lett. 33, 549-55 10.1007/s10529-010-0455-x
-
(2011)
Biotechnol. Lett.
, vol.33
, pp. 549-555
-
-
Ramon, A.1
Smith, H.O.2
-
23
-
-
84896142083
-
One step DNA assembly for combinatorial metabolic engineering
-
Coussement, P., Maertens, J., Beauprez, J., Van Bellegem, W., and De Mey, M. (2014) One step DNA assembly for combinatorial metabolic engineering Metab. Eng. 23, 70-77 10.1016/j.ymben.2014.02.012
-
(2014)
Metab. Eng.
, vol.23
, pp. 70-77
-
-
Coussement, P.1
Maertens, J.2
Beauprez, J.3
Van Bellegem, W.4
De Mey, M.5
-
24
-
-
68949161807
-
Programming cells by multiplex genome engineering and accelerated evolution
-
Wang, H. H., Isaacs, F. J., Carr, P. A., Sun, Z. Z., Xu, G., Forest, C. R., and Church, G. M. (2009) Programming cells by multiplex genome engineering and accelerated evolution Nature 460, 894-8 10.1038/nature08187
-
(2009)
Nature
, vol.460
, pp. 894-898
-
-
Wang, H.H.1
Isaacs, F.J.2
Carr, P.A.3
Sun, Z.Z.4
Xu, G.5
Forest, C.R.6
Church, G.M.7
-
25
-
-
77957329119
-
Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli
-
Ajikumar, P. K., Xiao, W.-H., Tyo, K. E. J., Wang, Y., Simeon, F., Leonard, E., Mucha, O., Phon, T. H., Pfeifer, B., and Stephanopoulos, G. (2010) Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli Science (Washington, DC, U. S.) 330, 70-4 10.1126/science.1191652
-
(2010)
Science (Washington, DC, U. S.)
, vol.330
, pp. 70-74
-
-
Ajikumar, P.K.1
Xiao, W.-H.2
Tyo, K.E.J.3
Wang, Y.4
Simeon, F.5
Leonard, E.6
Mucha, O.7
Phon, T.H.8
Pfeifer, B.9
Stephanopoulos, G.10
-
26
-
-
35548954677
-
Engineering microbial cell factories for biosynthesis of isoprenoid molecules: Beyond lycopene
-
Klein-Marcuschamer, D., Ajikumar, P. K., and Stephanopoulos, G. (2007) Engineering microbial cell factories for biosynthesis of isoprenoid molecules: beyond lycopene Trends Biotechnol. 25, 417-24 10.1016/j.tibtech.2007.07.006
-
(2007)
Trends Biotechnol.
, vol.25
, pp. 417-424
-
-
Klein-Marcuschamer, D.1
Ajikumar, P.K.2
Stephanopoulos, G.3
-
28
-
-
0028485650
-
Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942
-
Cunningham, F. X., Sun, Z., Chamovitz, D., Hirschberg, J., and Gantt, E. (1994) Molecular structure and enzymatic function of lycopene cyclase from the cyanobacterium Synechococcus sp strain PCC7942 Plant Cell 6, 1107-1121 10.2307/3869889
-
(1994)
Plant Cell
, vol.6
, pp. 1107-1121
-
-
Cunningham, F.X.1
Sun, Z.2
Chamovitz, D.3
Hirschberg, J.4
Gantt, E.5
-
29
-
-
68149136937
-
Circular polymerase extension cloning of complex gene libraries and pathways
-
Quan, J. and Tian, J. (2009) Circular polymerase extension cloning of complex gene libraries and pathways PLoS One 4, e6441 10.1371/journal.pone.0006441
-
(2009)
PLoS One
, vol.4
, pp. e6441
-
-
Quan, J.1
Tian, J.2
-
30
-
-
84874244066
-
High level production of tyrosinase in recombinant Escherichia coli
-
Ren, Q., Henes, B., Fairhead, M., and Thöny-Meyer, L. (2013) High level production of tyrosinase in recombinant Escherichia coli BMC Biotechnol. 13, 18 10.1186/1472-6750-13-18
-
(2013)
BMC Biotechnol.
, vol.13
, pp. 18
-
-
Ren, Q.1
Henes, B.2
Fairhead, M.3
Thöny-Meyer, L.4
-
31
-
-
2642574503
-
-
R Core Team (), R Foundation for Statistical Computing, Vienna, Austria
-
R Core Team (2015) A Language and Environment for Statistical Computing, R Foundation for Statistical Computing, Vienna, Austria.
-
(2015)
A Language and Environment for Statistical Computing
-
-
-
32
-
-
77950900814
-
Modeling with a view to target identification in metabolic engineering: A critical evaluation of the available tools
-
Maertens, J. and Vanrolleghem, P. A. (2010) Modeling with a view to target identification in metabolic engineering: a critical evaluation of the available tools Biotechnol. Prog. 26, 313-331 10.1002/btpr.349
-
(2010)
Biotechnol. Prog.
, vol.26
, pp. 313-331
-
-
Maertens, J.1
Vanrolleghem, P.A.2
-
33
-
-
33751245592
-
Combinatorial biosynthesis of medicinal plant secondary metabolites
-
Julsing, M. K., Koulman, A., Woerdenbag, H. J., Quax, W. J., and Kayser, O. (2006) Combinatorial biosynthesis of medicinal plant secondary metabolites Biomol. Eng. 23, 265-279 10.1016/j.bioeng.2006.08.001
-
(2006)
Biomol. Eng.
, vol.23
, pp. 265-279
-
-
Julsing, M.K.1
Koulman, A.2
Woerdenbag, H.J.3
Quax, W.J.4
Kayser, O.5
-
35
-
-
0031896232
-
Random mutagenesis by whole-plasmid PCR amplification
-
Parikh, A. and Guengerich, F. P. (1998) Random mutagenesis by whole-plasmid PCR amplification Biotechniques 24, 428-431
-
(1998)
Biotechniques
, vol.24
, pp. 428-431
-
-
Parikh, A.1
Guengerich, F.P.2
-
36
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman, R. C., Carey, V. J., and Bates, D. M. et al. 2004, Bioconductor: Open software development for computational biology and bioinformatics Genome Biology 5, R80 10.1186/gb-2004-5-10-r80
-
(2004)
Genome Biology
, vol.5
, pp. R80
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
-
37
-
-
79958279010
-
Generation of families of construct variants using golden gate shuffling
-
Engler, C. and Marillonnet, S. (2011) Generation of families of construct variants using golden gate shuffling Methods Mol. Biol. (N. Y., NY, U. S.) 729, 167-181 10.1007/978-1-61779-065-2-11
-
(2011)
Methods Mol. Biol. (N. Y., NY, U. S.)
, vol.729
, pp. 167-181
-
-
Engler, C.1
Marillonnet, S.2
-
38
-
-
84855188601
-
Type 2 IDI performs better than type 1 for improving lycopene production in metabolically engineered E. Coli strains
-
Rad, S. A., Zahiri, H. S., Noghabi, K. A., Rajaei, S., Heidari, R., and Mojallali, L. (2012) Type 2 IDI performs better than type 1 for improving lycopene production in metabolically engineered E. coli strains World J. Microbiol. Biotechnol. 28, 313-321 10.1007/s11274-011-0821-4
-
(2012)
World J. Microbiol. Biotechnol.
, vol.28
, pp. 313-321
-
-
Rad, S.A.1
Zahiri, H.S.2
Noghabi, K.A.3
Rajaei, S.4
Heidari, R.5
Mojallali, L.6
|