Adaptive laboratory evolution of a genome-reduced Escherichia coli

Nature Communications

Volumn 10, Issue 1, 2019, Pages

  Choe, Donghui ^a   Lee, Jun Hyoung ^a,b   Yoo, Minseob ^a   Hwang, Soonkyu ^a   Sung, Bong Hyun ^b,c   Cho, Suhyung ^a   Palsson, Bernhard ^d,e   Kim, Sun Chang ^a,b   Cho, Byung Kwan ^a,b  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Intelligent Synthetic Biology Center   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BACTERIAL DNA; BACTERIAL RNA; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RIBOSOME PROTEIN; RNA POLYMERASE; TRANSCRIPTOME; TRANSLATOME; UNCLASSIFIED DRUG; ESCHERICHIA COLI PROTEIN;

ADAPTIVE RADIATION; CHEMICAL BINDING; COLIFORM BACTERIUM; EVOLUTION; GENE EXPRESSION; GENETIC ANALYSIS; GENOME; LABORATORY METHOD; METABOLISM;

ADAPTIVE LABORATORY EVOLUTION; AMINO ACID METABOLISM; ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL MUTATION; BACTERIAL STRAIN; CARBON METABOLISM; CITRIC ACID CYCLE; CONTROLLED STUDY; DNA SYNTHESIS; DNA TRANSCRIPTION; ENZYME BINDING; ESCHERICHIA COLI; FED BATCH FERMENTATION; GENE FREQUENCY; GLYCOLYSIS; GROWTH INHIBITION; HETEROLOGOUS EXPRESSION; MOLECULAR EVOLUTION; MUTATION RATE; NONHUMAN; NUCLEIC ACID METABOLISM; OMICS; POINT MUTATION; PROMOTER REGION; PROTEIN EXPRESSION; RPOD GENE; SINGLE NUCLEOTIDE POLYMORPHISM; STOP CODON; SYSTEMS BIOLOGY; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; TRANSLATION INITIATION; TRANSLATOMICS; UPREGULATION; WHOLE GENOME SEQUENCING; CLASSIFICATION; GENE EXPRESSION REGULATION; GENETICS; GENOME SIZE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; PHENOTYPE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, BACTERIAL; GENOME SIZE; GENOME, BACTERIAL; MUTATION; PHENOTYPE; TRANSCRIPTOME;

EID: 85062101707     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-019-08888-6     Document Type: Article

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