Modeling neuropsychiatric disorders using human induced pluripotent stem cells

Protein and Cell

Volumn 11, Issue 1, 2020, Pages 45-59

  Wang, Meiyan ^a,b   Zhang, Lei ^a   Gage, Fred H ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

autism spectrum disorder; bipolar disorder; brain organoid; iPSCs; neuropsychiatric disorders; schizophrenia

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BONE MORPHOGENETIC PROTEIN; DICKKOPF 1 PROTEIN; DISKS LARGE HOMOLOG 4; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; FIBROBLAST GROWTH FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR 1; LITHIUM; MICRORNA; PARVALBUMIN; PROSPERO HOMEOBOX PROTEIN 1; PROTEIN S 100; PROTEIN S100B; RETINOIC ACID; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR EMX2; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ALEXANDER DISEASE; ASTROCYTE; AUTISM; BIPOLAR DISORDER; CELL DIFFERENTIATION; CELL FUNCTION; CELL STRUCTURE; CEREBRAL ORGANOID; CORTICAL EXCITABILITY; DEPRESSION; DORSOLATERAL PREFRONTAL CORTEX; GENE EXPRESSION; GENETIC VARIABILITY; GENETIC VARIATION; HIPPOCAMPUS; HUMAN; HUMAN EMBRYONIC STEM CELL; INDUCED PLURIPOTENT STEM CELL; MENTAL DISEASE; MICROGLIA; MILLER DIEKER SYNDROME; MYELINATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OLIGODENDROGLIA; PATHOGENESIS; PHELAN-MCDERMID SYNDROME; PHENOTYPE; PRIORITY JOURNAL; PSYCHOSIS; RABIES; RETT SYNDROME; REVIEW; SCHIZOPHRENIA; SOMATIC CELL; TRANSCRIPTOME SEQUENCING; BIOLOGICAL MODEL; BRAIN; ORGANOID; PATHOLOGY;

BRAIN; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MENTAL DISORDERS; MODELS, BIOLOGICAL; ORGANOIDS;

EID: 85076608352     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-019-0638-8     Document Type: Review

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