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Volumn 7, Issue , 2016, Pages

The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model

Author keywords

[No Author keywords available]

Indexed keywords

DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; MICRORNA; MICRORNA 219; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TLX; UNCLASSIFIED DRUG; CELL RECEPTOR; DISC1 PROTEIN, HUMAN; MIRN219 MICRORNA, HUMAN; MIRN219 MICRORNA, MOUSE; NERVE PROTEIN; NR2E1 PROTEIN, HUMAN; NR2E1 PROTEIN, MOUSE; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR;

EID: 84961709637     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10965     Document Type: Article
Times cited : (94)

References (68)
  • 1
    • 0027992358 scopus 로고
    • Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx
    • Yu R. T, McKeown M, Evans R. M, & Umesono K. Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx. Nature. 370, 375-379 (1994).
    • (1994) Nature , vol.370 , pp. 375-379
    • Yu, R.T.1    McKeown, M.2    Evans, R.M.3    Umesono, K.4
  • 2
    • 0031465159 scopus 로고    scopus 로고
    • Defective limbic system in mice lacking the tailless gene
    • Monaghan A. P, et al. Defective limbic system in mice lacking the tailless gene. Nature. 390, 515-517 (1997).
    • (1997) Nature , vol.390 , pp. 515-517
    • Monaghan, A.P.1
  • 3
    • 0347719238 scopus 로고    scopus 로고
    • Expression and function of orphan nuclear receptor TLX in adult neural stem cells
    • Shi Y, et al. Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature. 427, 78-83 (2004).
    • (2004) Nature , vol.427 , pp. 78-83
    • Shi, Y.1
  • 4
    • 38049046645 scopus 로고    scopus 로고
    • Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain
    • Li W, et al. Nuclear receptor TLX regulates cell cycle progression in neural stem cells of the developing brain. Mol. Endocrinol. 22, 56-64 (2008).
    • (2008) Mol. Endocrinol , vol.22 , pp. 56-64
    • Li, W.1
  • 5
    • 78149302213 scopus 로고    scopus 로고
    • Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal
    • sup 31-39
    • Qu Q, et al. Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nat. Cell Biol. 12, 31-40; sup pp 31-39 (2010).
    • (2010) Nat. Cell Biol , vol.12 , pp. 31-40
    • Qu, Q.1
  • 6
    • 39149099035 scopus 로고    scopus 로고
    • A role for adult TLX-positive neural stem cells in learning and behaviour
    • Zhang C. L, Zou Y, He W, Gage F. H, & Evans R. M. A role for adult TLX-positive neural stem cells in learning and behaviour. Nature 451 1004-1007 (2008).
    • (2008) Nature , vol.451 , pp. 1004-1007
    • Zhang, C.L.1    Zou, Y.2    He, W.3    Gage, F.H.4    Evans, R.M.5
  • 7
    • 84903445816 scopus 로고    scopus 로고
    • Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model
    • Murai K, et al. Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model. Proc. Natl Acad. Sci. USA. 111, 9115-9120 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. 9115-9120
    • Murai, K.1
  • 8
    • 4644297655 scopus 로고    scopus 로고
    • The Tlx gene regulates the timing of neurogenesis in the cortex
    • Roy K, et al. The Tlx gene regulates the timing of neurogenesis in the cortex. J. Neurosci. 24, 8333-8345 (2004).
    • (2004) J. Neurosci , vol.24 , pp. 8333-8345
    • Roy, K.1
  • 9
    • 0345305682 scopus 로고    scopus 로고
    • Tlx controls proliferation and patterning of lateral telencephalic progenitor domains
    • Stenman J. M, Wang B, & Campbell K. Tlx controls proliferation and patterning of lateral telencephalic progenitor domains. J. Neurosci. 23, 10568-10576 (2003).
    • (2003) J. Neurosci , vol.23 , pp. 10568-10576
    • Stenman, J.M.1    Wang, B.2    Campbell, K.3
  • 10
    • 76649088031 scopus 로고    scopus 로고
    • MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling
    • Zhao C, et al. microRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc. Natl Acad. Sci. USA. 107, 1876-1881 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 1876-1881
    • Zhao, C.1
  • 11
    • 34848818037 scopus 로고    scopus 로고
    • Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
    • Sun G, Yu R. T, Evans R. M, & Shi Y. Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation. Proc. Natl Acad. Sci. USA. 104, 15282-15287 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 15282-15287
    • Sun, G.1    Yu, R.T.2    Evans, R.M.3    Shi, Y.4
  • 12
    • 77950675541 scopus 로고    scopus 로고
    • Histone demethylase LSD1 regulates neural stem cell proliferation
    • Sun G, et al. Histone demethylase LSD1 regulates neural stem cell proliferation. Mol. Cell. Biol. 30, 1997-2005 (2010).
    • (2010) Mol. Cell. Biol , vol.30 , pp. 1997-2005
    • Sun, G.1
  • 13
    • 44949122682 scopus 로고    scopus 로고
    • Transrepressive function of TLX requires the histone demethylase LSD1
    • Yokoyama A, Takezawa S, Schule R, Kitagawa H, & Kato S. Transrepressive function of TLX requires the histone demethylase LSD1. Mol. Cell. Biol. 28, 3995-4003 (2008).
    • (2008) Mol. Cell. Biol , vol.28 , pp. 3995-4003
    • Yokoyama, A.1    Takezawa, S.2    Schule, R.3    Kitagawa, H.4    Kato, S.5
  • 14
    • 64049095014 scopus 로고    scopus 로고
    • A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination
    • Zhao C, Sun G, Li S, & Shi Y. A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nat. Struct. Mol. Biol. 16, 365-371 (2009).
    • (2009) Nat Struct. Mol. Biol , vol.16 , pp. 365-371
    • Zhao, C.1    Sun, G.2    Li, S.3    Shi, Y.4
  • 15
    • 67650469708 scopus 로고    scopus 로고
    • Transcriptional activation of NAD-dependent protein deacetylase SIRT1 by nuclear receptor TLX
    • Iwahara N, Hisahara S, Hayashi T, & Horio Y. Transcriptional activation of NAD-dependent protein deacetylase SIRT1 by nuclear receptor TLX. Biochem. Biophys. Res. Commun. 386, 671-675 (2009).
    • (2009) Biochem. Biophys. Res. Commun , vol.386 , pp. 671-675
    • Iwahara, N.1    Hisahara, S.2    Hayashi, T.3    Horio, Y.4
  • 16
    • 77955775178 scopus 로고    scopus 로고
    • TLX activates MASH1 for induction of neuronal lineage commitment of adult hippocampal neuroprogenitors
    • Elmi M, et al. TLX activates MASH1 for induction of neuronal lineage commitment of adult hippocampal neuroprogenitors. Mol. Cell. Neurosci. 45, 121-131 (2010).
    • (2010) Mol. Cell. Neurosci , vol.45 , pp. 121-131
    • Elmi, M.1
  • 17
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 116, 281-297 (2004).
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 18
    • 34247876168 scopus 로고    scopus 로고
    • DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs
    • Fukuda T, et al. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat. Cell Biol. 9, 604-611 (2007).
    • (2007) Nat. Cell Biol , vol.9 , pp. 604-611
    • Fukuda, T.1
  • 19
    • 9144225636 scopus 로고    scopus 로고
    • The Microprocessor complex mediates the genesis of microRNAs
    • Gregory R. I, et al. The Microprocessor complex mediates the genesis of microRNAs. Nature. 432, 235-240 (2004).
    • (2004) Nature , vol.432 , pp. 235-240
    • Gregory, R.I.1
  • 20
    • 49349104315 scopus 로고    scopus 로고
    • The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): Novel transcriptional co-regulators
    • Fuller-Pace F. V, & Ali S. The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators. Biochem. Soc. Trans. 36, 609-612 (2008).
    • (2008) Biochem. Soc. Trans , vol.36 , pp. 609-612
    • Fuller-Pace, F.V.1    Ali, S.2
  • 21
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • Davis B. N, Hilyard A. C, Lagna G, & Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature. 454, 56-61 (2008).
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 22
    • 67749143728 scopus 로고    scopus 로고
    • Modulation of microRNA processing by p53
    • Suzuki H. I, et al. Modulation of microRNA processing by p53. Nature. 460, 529-533 (2009).
    • (2009) Nature , vol.460 , pp. 529-533
    • Suzuki, H.I.1
  • 23
    • 84861944845 scopus 로고    scopus 로고
    • BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex
    • Kawai S, & Amano A. BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex. J. Cell Biol. 197, 201-208 (2012).
    • (2012) J. Cell Biol , vol.197 , pp. 201-208
    • Kawai, S.1    Amano, A.2
  • 24
    • 34249713720 scopus 로고    scopus 로고
    • MicroRNA modulation of circadian-clock period and entrainment
    • Cheng H. Y, et al. microRNA modulation of circadian-clock period and entrainment. Neuron. 54, 813-829 (2007).
    • (2007) Neuron , vol.54 , pp. 813-829
    • Cheng, H.Y.1
  • 25
    • 33847203593 scopus 로고    scopus 로고
    • Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus
    • Lukiw W. J. Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport. 18, 297-300 (2007).
    • (2007) Neuroreport , vol.18 , pp. 297-300
    • Lukiw, W.J.1
  • 26
    • 77649175470 scopus 로고    scopus 로고
    • Dicer1 and miR-219 are required for normal oligodendrocyte differentiation and myelination
    • Dugas J. C, et al. Dicer1 and miR-219 are required for normal oligodendrocyte differentiation and myelination. Neuron. 65, 597-611 (2010).
    • (2010) Neuron , vol.65 , pp. 597-611
    • Dugas, J.C.1
  • 27
    • 77649166937 scopus 로고    scopus 로고
    • MicroRNA-mediated control of oligodendrocyte differentiation
    • Zhao X, et al. MicroRNA-mediated control of oligodendrocyte differentiation. Neuron. 65, 612-626 (2010).
    • (2010) Neuron , vol.65 , pp. 612-626
    • Zhao, X.1
  • 28
    • 84888199706 scopus 로고    scopus 로고
    • MiR-219 regulates neural precursor differentiation by direct inhibition of apical par polarity proteins
    • Hudish L. I, Blasky A. J, & Appel B. miR-219 regulates neural precursor differentiation by direct inhibition of apical par polarity proteins. Dev. Cell. 27, 387-398 (2013).
    • (2013) Dev. Cell , vol.27 , pp. 387-398
    • Hudish, L.I.1    Blasky, A.J.2    Appel, B.3
  • 30
    • 41849133938 scopus 로고    scopus 로고
    • Dysregulation of miRNA 181b in the temporal cortex in schizophrenia
    • Beveridge N. J, et al. Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. Hum. Mol. Genet. 17, 1156-1168 (2008).
    • (2008) Hum. Mol. Genet , vol.17 , pp. 1156-1168
    • Beveridge, N.J.1
  • 31
    • 78650511568 scopus 로고    scopus 로고
    • Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia
    • Santarelli D. M, Beveridge N. J, Tooney P. A, & Cairns M. J. Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia. Biol. Psychiatry. 69, 180-187 (2011).
    • (2011) Biol. Psychiatry , vol.69 , pp. 180-187
    • Santarelli, D.M.1    Beveridge, N.J.2    Tooney, P.A.3    Cairns, M.J.4
  • 32
    • 84899903262 scopus 로고    scopus 로고
    • Expression of microRNAs and other small RNAs in prefrontal cortex in schizophrenia, bipolar disorder and depressed subjects
    • Smalheiser N. R, et al. Expression of microRNAs and other small RNAs in prefrontal cortex in schizophrenia, bipolar disorder and depressed subjects. PLoS ONE. 9, e86469 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e86469
    • Smalheiser, N.R.1
  • 34
    • 33745880884 scopus 로고    scopus 로고
    • PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling
    • Jackson E. L, et al. PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling. Neuron. 51, 187-199 (2006).
    • (2006) Neuron , vol.51 , pp. 187-199
    • Jackson, E.L.1
  • 35
    • 64549109671 scopus 로고    scopus 로고
    • Vectors expressing efficient RNA decoys achieve the long-Term suppression of specific microRNA activity in mammalian cells
    • Haraguchi T, Ozaki Y, & Iba H. Vectors expressing efficient RNA decoys achieve the long-Term suppression of specific microRNA activity in mammalian cells. Nucleic Acids Res. 37, e43 (2009).
    • (2009) Nucleic Acids Res , vol.37 , pp. e43
    • Haraguchi, T.1    Ozaki, Y.2    Iba, H.3
  • 36
    • 23744517093 scopus 로고    scopus 로고
    • A frameshift mutation in disrupted in schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder
    • Sachs N. A, et al. A frameshift mutation in disrupted in schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder. Mol. Psychiatry. 10, 758-764 (2005).
    • (2005) Mol Psychiatry , vol.10 , pp. 758-764
    • Sachs, N.A.1
  • 37
    • 79953048441 scopus 로고    scopus 로고
    • Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation
    • Chiang C. H, et al. Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation. Mol. Psychiatry. 16, 358-360 (2011).
    • (2011) Mol. Psychiatry , vol.16 , pp. 358-360
    • Chiang, C.H.1
  • 38
    • 84911360325 scopus 로고    scopus 로고
    • Synaptic dysregulation in a human iPS cell model of mental disorders
    • Wen Z, et al. Synaptic dysregulation in a human iPS cell model of mental disorders. Nature. 515, 414-418 (2014).
    • (2014) Nature , vol.515 , pp. 414-418
    • Wen, Z.1
  • 39
    • 33646377899 scopus 로고    scopus 로고
    • Neural stem cell proliferation is decreased in schizophrenia, but not in depression
    • Reif A, et al. Neural stem cell proliferation is decreased in schizophrenia, but not in depression. Mol. Psychiatry. 11, 514-522 (2006).
    • (2006) Mol. Psychiatry , vol.11 , pp. 514-522
    • Reif, A.1
  • 40
    • 62149083806 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling
    • Mao Y, et al. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell. 136, 1017-1031 (2009).
    • (2009) Cell , vol.136 , pp. 1017-1031
    • Mao, Y.1
  • 41
    • 79955596140 scopus 로고    scopus 로고
    • DISC1-dependent switch from progenitor proliferation to migration in the developing cortex
    • Ishizuka K, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature. 473, 92-96 (2011).
    • (2011) Nature , vol.473 , pp. 92-96
    • Ishizuka, K.1
  • 42
    • 78751689926 scopus 로고    scopus 로고
    • Investigation of post-Transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines
    • Sarachana T, Zhou R, Chen G, Manji H. K, & Hu V. W. Investigation of post-Transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines. Genome Med. 2, 23 (2010).
    • (2010) Genome Med , vol.2 , pp. 23
    • Sarachana, T.1    Zhou, R.2    Chen, G.3    Manji, H.K.4    Hu, V.W.5
  • 43
    • 77957734498 scopus 로고    scopus 로고
    • Genetic variants and abnormal processing of pre-miR-182, a circadian clock modulator, in major depression patients with late insomnia
    • Saus E, et al. Genetic variants and abnormal processing of pre-miR-182, a circadian clock modulator, in major depression patients with late insomnia. Hum. Mol. Genet. 19, 4017-4025 (2010).
    • (2010) Hum. Mol. Genet , vol.19 , pp. 4017-4025
    • Saus, E.1
  • 44
    • 56749156453 scopus 로고    scopus 로고
    • PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice
    • Rivers L. E, et al. PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat. Neurosci. 11, 1392-1401 (2008).
    • (2008) Nat. Neurosci , vol.11 , pp. 1392-1401
    • Rivers, L.E.1
  • 45
    • 66649124599 scopus 로고    scopus 로고
    • Identifying and treating cognitive impairment in bipolar disorder
    • Goldberg J. F, & Chengappa K. N. Identifying and treating cognitive impairment in bipolar disorder. Bipolar Disord. 11 (Suppl 2), 123-137 (2009).
    • (2009) Bipolar Disord , vol.11 , pp. 123-137
    • Goldberg, J.F.1    Chengappa, K.N.2
  • 46
    • 0024999833 scopus 로고
    • Structural brain abnormalities in bipolar affective disorder Ventricular enlargement and focal signal hyperintensities
    • Swayze, 2nd V. W, Andreasen N. C, Alliger R. J, Ehrhardt J. C, & Yuh W. T. Structural brain abnormalities in bipolar affective disorder. Ventricular enlargement and focal signal hyperintensities. Arch. Gen. Psychiatry. 47, 1054-1059 (1990).
    • (1990) Arch. Gen. Psychiatry , vol.47 , pp. 1054-1059
    • Swayze, V.W.1    Andreasen, N.C.2    Alliger, R.J.3    Ehrhardt, J.C.4    Yuh, W.T.5
  • 47
    • 0037076496 scopus 로고    scopus 로고
    • Fierce: A new mouse deletion of Nr2e1; Violent behaviour and ocular abnormalities are background-dependent
    • Young K. A, et al. Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent. Behav. Brain Res. 132, 145-158 (2002).
    • (2002) Behav. Brain Res , vol.132 , pp. 145-158
    • Young, K.A.1
  • 48
    • 34247619460 scopus 로고    scopus 로고
    • Behavioral phenotypes of Disc1 missense mutations in mice
    • Clapcote S. J, et al. Behavioral phenotypes of Disc1 missense mutations in mice. Neuron. 54, 387-402 (2007).
    • (2007) Neuron , vol.54 , pp. 387-402
    • Clapcote, S.J.1
  • 49
    • 35448988145 scopus 로고    scopus 로고
    • Dominant-negative DISC1 transgenic mice display schizophrenia-Associated phenotypes detected by measures translatable to humans
    • Hikida T, et al. Dominant-negative DISC1 transgenic mice display schizophrenia-Associated phenotypes detected by measures translatable to humans. Proc. Natl Acad. Sci. USA. 104, 14501-14506 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 14501-14506
    • Hikida, T.1
  • 51
    • 44349132300 scopus 로고    scopus 로고
    • A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition
    • Kvajo M, et al. A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition. Proc. Natl Acad. Sci. USA. 105, 7076-7081 (2008).
    • (2008) Proc Natl Acad. Sci. USA , vol.105 , pp. 7076-7081
    • Kvajo, M.1
  • 52
    • 36749042144 scopus 로고    scopus 로고
    • Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice
    • Li W, et al. Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice. Proc. Natl Acad. Sci. USA. 104, 18280-18285 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 18280-18285
    • Li, W.1
  • 53
    • 76849102959 scopus 로고    scopus 로고
    • Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits
    • Niwa M, et al. Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits. Neuron. 65, 480-489 (2010).
    • (2010) Neuron , vol.65 , pp. 480-489
    • Niwa, M.1
  • 54
    • 38349172768 scopus 로고    scopus 로고
    • Enlargement of the lateral ventricles in mutant DISC1 transgenic mice
    • Pletnikov M. V, et al. Enlargement of the lateral ventricles in mutant DISC1 transgenic mice. Mol. Psychiatry. 13, 115 (2008).
    • (2008) Mol. Psychiatry , vol.13 , pp. 115
    • Pletnikov, M.V.1
  • 55
    • 58149174266 scopus 로고    scopus 로고
    • Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1
    • Shen S, et al. Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1. J. Neurosci. 28, 10893-10904 (2008).
    • (2008) J. Neurosci , vol.28 , pp. 10893-10904
    • Shen, S.1
  • 56
    • 48949087605 scopus 로고    scopus 로고
    • The anatomy of first-episode and chronic schizophrenia: An anatomical likelihood estimation meta-Analysis
    • Ellison-Wright I, Glahn D. C, Laird A. R, Thelen S. M, & Bullmore E. The anatomy of first-episode and chronic schizophrenia: an anatomical likelihood estimation meta-Analysis. Am. J. Psychiatry. 165, 1015-1023 (2008).
    • (2008) Am. J. Psychiatry , vol.165 , pp. 1015-1023
    • Ellison-Wright, I.1    Glahn, D.C.2    Laird, A.R.3    Thelen, S.M.4    Bullmore, E.5
  • 57
    • 84856215758 scopus 로고    scopus 로고
    • MicroRNA networks direct neuronal development and plasticity
    • Olde Loohuis N. F, et al. MicroRNA networks direct neuronal development and plasticity. Cell. Mol. Life Sci. 69, 89-102 (2012).
    • (2012) Cell. Mol. Life Sci , vol.69 , pp. 89-102
    • Olde Loohuis, N.F.1
  • 58
    • 62549091540 scopus 로고    scopus 로고
    • MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction
    • Kocerha J, et al. MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proc. Natl Acad. Sci. USA. 106, 3507-3512 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 3507-3512
    • Kocerha, J.1
  • 59
    • 8444245975 scopus 로고    scopus 로고
    • Disruption of neurogenesis on gestational day 17 in the rat causes behavioral changes relevant to positive and negative schizophrenia symptoms and alters amphetamine-induced dopamine release in nucleus accumbens
    • Flagstad P, et al. Disruption of neurogenesis on gestational day 17 in the rat causes behavioral changes relevant to positive and negative schizophrenia symptoms and alters amphetamine-induced dopamine release in nucleus accumbens. Neuropsychopharmacology. 29, 2052-2064 (2004).
    • (2004) Neuropsychopharmacology , vol.29 , pp. 2052-2064
    • Flagstad, P.1
  • 60
    • 34548101950 scopus 로고    scopus 로고
    • Neurogenic actions of atypical antipsychotic drugs and therapeutic implications
    • Newton S. S, & Duman R. S. Neurogenic actions of atypical antipsychotic drugs and therapeutic implications. CNS Drugs. 21, 715-725 (2007).
    • (2007) CNS Drugs , vol.21 , pp. 715-725
    • Newton, S.S.1    Duman, R.S.2
  • 61
    • 84924721164 scopus 로고    scopus 로고
    • Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
    • Brennand K, et al. Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. Mol. Psychiatry. 20, 361-368 (2014).
    • (2014) Mol. Psychiatry , vol.20 , pp. 361-368
    • Brennand, K.1
  • 62
    • 84904001347 scopus 로고    scopus 로고
    • Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity
    • Yoon K. J, et al. Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity. Cell Stem Cell. 15, 79-91 (2014).
    • (2014) Cell Stem Cell , vol.15 , pp. 79-91
    • Yoon, K.J.1
  • 63
    • 82555196537 scopus 로고    scopus 로고
    • MiR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells
    • Sun G, et al. miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells. Nat. Commun. 2, 529 (2011).
    • (2011) Nat. Commun , vol.2 , pp. 529
    • Sun, G.1
  • 64
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Lee Y, et al. The nuclear RNase III Drosha initiates microRNA processing. Nature. 425, 415-419 (2003).
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1
  • 65
    • 84927710889 scopus 로고    scopus 로고
    • Molecular properties, functional mechanisms, and applications of sliced siRNA
    • Sun G, et al. Molecular properties, functional mechanisms, and applications of sliced siRNA. Mol. Ther. Nucleic Acids. 4, e221 (2015).
    • (2015) Mol. Ther. Nucleic Acids , vol.4 , pp. e221
    • Sun, G.1
  • 66
    • 70349130726 scopus 로고    scopus 로고
    • DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212
    • Kim J. Y, et al. DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. Neuron. 63, 761-773 (2009).
    • (2009) Neuron , vol.63 , pp. 761-773
    • Kim, J.Y.1
  • 68
    • 33845275018 scopus 로고    scopus 로고
    • RIP-Chip: The isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts
    • Keene J. D, Komisarow J. M, & Friedersdorf M. B. RIP-Chip: the isolation and identification of mRNAs, microRNAs and protein components of ribonucleoprotein complexes from cell extracts. Nat. Protoc. 1, 302-307 (2006).
    • (2006) Nat. Protoc , vol.1 , pp. 302-307
    • Keene, J.D.1    Komisarow, J.M.2    Friedersdorf, M.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.