CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons

Nature Cell Biology

Volumn 14, Issue 9, 2012, Pages 911-923

  Ricciardi, Sara ^a   Ungaro, Federica ^a   Hambrock, Melanie ^b   Rademacher, Nils ^b   Stefanelli, Gilda ^a   Brambilla, Dario ^c   Sessa, Alessandro ^a   Magagnotti, Cinzia ^a   Bachi, Angela ^a   Giarda, Elisa ^d   Verpelli, Chiara ^e   Kilstrup Nielsen, Charlotte ^d   Sala, Carlo ^e   Kalscheuer, Vera M ^b   Broccoli, Vania ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY OF INSUBRIA   (Italy)

^e CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE LIKE 5; NETGRIN G1; POSTSYNAPTIC DENSITY PROTEIN 95; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL ACTIVITY; CELL ADHESION; CELL STRUCTURE; CONTROLLED STUDY; DENDRITIC SPINE; EMBRYO; ENZYME ACTIVITY; ENZYME BINDING; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SYNAPTIC TRANSMISSION;

AMINO ACID SEQUENCE; ANIMALS; CELL ADHESION; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; DENDRITIC SPINES; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; GLUTAMIC ACID; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; NERVE TISSUE PROTEINS; NEURONS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, CELL SURFACE; RETT SYNDROME; SPINE; SYNAPSES;

MUS; RODENTIA;

EID: 84865773360     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2566     Document Type: Article

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