Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Wang, Liqun ^a   Xia, Jing ^b   Li, Jonathan ^c   Hagemann, Tracy L ^d   Jones, Jeffrey R ^d   Fraenkel, Ernest ^c   Weitz, David A ^b   Zhang, Su Chun ^d,e   Messing, Albee ^d,f   Feany, Mel B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c Massachusetts Institute of Technology   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^f UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTEGRIN; CYTOSKELETON PROTEIN; F ACTIN; FOCAL ADHESION KINASE; LAMIN A; LAMIN C; LAMININ; NUCLEAR PROTEIN; PLECTIN; UNCLASSIFIED DRUG; VINCULIN; YES ASSOCIATED PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPO PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE;

CELL; DISABILITY; DISEASE; GENE EXPRESSION; INJURY; MUTATION; PATHOGENICITY; RIGIDITY;

ADULT; ALEXANDER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CELL; BRAIN CELL RIGIDITY; BRAIN TISSUE; BRAIN TISSUE RIGIDITY; CHILD; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FEMALE; FOCAL ADHESION; FRONTAL CORTEX; FRUIT FLY MODEL; GAIN OF FUNCTION MUTATION; HIPPO SIGNALING; HUMAN; HUMAN CELL; MALE; MECHANOTRANSDUCTION; MOUSE; NERVE DEGENERATION; NERVOUS SYSTEM PARAMETERS; NEUROPATHOLOGY; NONHUMAN; PROTEIN INTERACTION; UPREGULATION; ADOLESCENT; ANIMAL; ANIMAL BEHAVIOR; BIOMECHANICS; BRAIN; BRAIN CHEMISTRY; CHEMISTRY; DROSOPHILA; GENETICS; GLIA; INFANT; METABOLISM; PRESCHOOL CHILD; PSYCHOLOGY; TRANSGENIC MOUSE; YOUNG ADULT;

ADOLESCENT; ADULT; ALEXANDER DISEASE; ANIMALS; BEHAVIOR, ANIMAL; BIOMECHANICAL PHENOMENA; BRAIN; BRAIN CHEMISTRY; CHILD; CHILD, PRESCHOOL; DROSOPHILA; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; INFANT; LAMIN TYPE A; MALE; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, TRANSGENIC; NEUROGLIA; PROTEIN-SERINE-THREONINE KINASES; YOUNG ADULT;

EID: 85047060011     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-018-04269-7     Document Type: Article

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