Biological insights from 108 schizophrenia-associated genetic loci

Nature

Volumn 511, Issue 7510, 2014, Pages 421-427

  Ripke, Stephan ^a,b   Neale, Benjamin M ^a,b   Corvin, Aiden ^c   Walters, James T R ^d   Farh, Kai How ^a   Holmans, Peter A ^d,e   Lee, Phil ^a,b   Bulik Sullivan, Brendan ^a,b   Collier, David A ^f,g   Huang, Hailiang ^a,b   Pers, Tune H ^b,h,i   Agartz, Ingrid ^j,k,l   Agerbo, Esben ^m,n   Albus, Margot ^o   Alexander, Madeline ^p   Amin, Farooq ^q,r   Bacanu, Silviu A ^s   Begemann, Martin ^t   Belliveau Jr , Richard A ^b   Bene, Judit ^u   Bergen, Sarah E ^b,j   Bevilacqua, Elizabeth ^b   Bigdeli, Tim B ^s   Black, Donald W ^v   Bruggeman, Richard ^w   Buccola, Nancy G ^x   Buckner, Randy L ^a,y   Byerley, William ^z   Cahn, Wiepke ^aa   Cai, Guiqing ^ab   Campion, Dominique ^ac   Cantor, Rita M ^ad   Carr, Vaughan J ^ae,af   Carrera, Noa ^d   Catts, Stanley V ^ae,ag   Chambert, Kimberly D ^b   Chan, Raymond C K ^ah   Chen, Ronald Y L ^ai   Chen, Eric Y H ^ai,aj   Cheng, Wei ^ak   Cheung, Eric F C ^al   Chong, Siow Ann ^am   Cloninger, C Robert ^an   Cohen, David ^ao   Cohen, Nadine ^ap   Cormican, Paul ^c   Craddock, Nick ^d,e   Crowley, James J ^aq   Curtis, David ^ar,as   Davidson, Michael ^at   Davis, Kenneth L ^ab   Degenhardt, Franziska ^au,av   Del Favero, Jurgen ^aw   Demontis, Ditte ^m,n   Dikeos, Dimitris ^ax   Dinan, Timothy ^ay   Djurovic, Srdjan ^l,az   Donohoe, Gary ^c,ba   Drapeau, Elodie ^ab   Duan, Jubao ^bb,bc   Dudbridge, Frank ^bd   Durmishi, Naser ^be   Eichhammer, Peter ^bf   Eriksson, Johan ^bg,bh,bi   Escott Price, Valentina ^d   Essioux, Laurent ^bj   Fanous, Ayman H ^bk,bl,bm,bn   Farrell, Martilias S ^aq   Frank, Josef ^bo   Franke, Lude ^w   Freedman, Robert ^bp   Freimer, Nelson B ^bq   Friedl, Marion ^br   Friedman, Joseph I ^ab   Fromer, Menachem ^a,b,ab   Genovese, Giulio ^b   Georgieva, Lyudmila ^d   Giegling, Ina ^br,bs   Giusti Rodríguez, Paola ^aq   Godard, Stephanie ^bt   Goldstein, Jacqueline I ^a,b   Golimbet, Vera ^bu   Gopal, Srihari ^bv   Gratten, Jacob ^ag   De Haan, Lieuwe ^bw   Hammer, Christian ^t   Hamshere, Marian L ^d   Hansen, Mark ^bx   Hansen, Thomas ^n,by   Haroutunian, Vahram ^ab,bn   Hartmann, Annette M ^br   Henskens, Frans A ^ae,bz,ca   Herms, Stefan ^au,av,cb   Hirschhorn, Joel N ^b,i,cc   Hoffmann, Per ^au,av,cb   Hofman, Andrea ^au,av   Hollegaard, Mads V ^cd   Hougaard, David M ^cd   Ikeda, Masashi ^ce   Joa, Inge ^cf   Julià, Antonio ^cg   Kahn, René S ^aa   Kalaydjieva, Luba ^ch   Karachanak Yankova, Sena ^ci   Karjalainen, Juha ^w   Kavanagh, David ^d   Keller, Matthew C ^cj   Kennedy, James L ^ck,cl,cm   Khrunin, Andrey ^cn   Kim, Yunjung ^aq   Klovins, Janis ^co   Knowles, James A ^bl   Konte, Bettina ^br   Kucinskas, Vaidutis ^cp   Kucinskiene, Zita Ausrele ^cp   Kuzelova Ptackova, Hana ^cq   Kähler, Anna K ^j   Laurent, Claudine ^p,cr   Keong, Jimmy Lee Chee ^am,cs   Lee, S Hong ^ag   Legge, Sophie E ^d   Lerer, Bernard ^ct   Li, Miaoxin ^ai,aj,cu   Li, Tao ^cv   Liang, Kung Yee ^cw   Lieberman, Jeffrey ^cx   Limborska, Svetlana ^cn   Loughland, Carmel M ^ae,ca   Lubinski, Jan ^cy   Lönnqvist, Jouko ^bi   Macek Jr , Milan ^cq   Magnusson, Patrik K E ^j   Maher, Brion S ^cw   Maier, Wolfgang ^av   Mallet, Jacques ^bt   Marsal, Sara ^cg   Mattheisen, Manuel ^m,n,av   Mattingsdal, Morten ^l,cz   McCarley, Robert W ^cc,da   McDonald, Colm ^ba   McIntosh, Andrew M ^db   Meier, Sandra ^bo   Meijer, Carin J ^bw   Melegh, Bela ^u   Melle, Ingrid ^l,az   Mesholam Gately, Raquelle I ^cc,dc   Metspalu, Andres ^dd   Michie, Patricia T ^ae,ca   Milani, Lili ^dd   Milanova, Vihra ^ci   Mokrab, Younes ^f   Morris, Derek W ^c,ba   Mors, Ole ^m,n,de   Murphy, Kieran C ^df   Murray, Robin M ^g   Myin Germeys, Inez ^dg   Müller Myhsok, Bertram ^dh,di,dj   Nelis, Mari ^dd   Nenadic, Igor ^dk   Nertney, Deborah A ^ag   Nestadt, Gerald ^dl   Nicodemus, Kristin K ^c   Nikitina Zake, Liene ^co   Nisenbaum, Laura ^f   Nordin, Annelie ^dm   O'Callaghan, Eadbhard ^dn   O'Dushlaine, Colm ^b   O'Neill, F Anthony ^do   Oh, Sang Yun ^dp   Olincy, Ann ^bp   Olsen, Line ^n,by   Van Os, Jim ^g,dg,dq   Pantelis, Christos ^ae,dr   Papadimitriou, George N ^ax   Papiol, Sergi ^t   Parkhomenko, Elena ^ab   Pato, Michele T ^bl   Paunio, Tiina ^bi,ds   Pejovic Milovancevic, Milica ^dt   Perkins, Diana O ^aq   Pietiläinen, Olli ^bi,ds   Pimm, Jonathan ^as   Pocklington, Andrew J ^d   Powell, John ^g   Price, Alkes ^b,du   Pulver, Ann E ^dl   Purcell, Shaun M ^ab   Quested, Digby ^dv   Rasmussen, Henrik B ^n,by   Reichenberg, Abraham ^ab   Reimers, Mark A ^s   Richards, Alexander L ^d   Roffman, Joshua L ^a   Roussos, Panos ^ab   Ruderfer, Douglas M ^d,ab   Salomaa, Veikko ^bi   Sanders, Alan R ^bb,bc   Schall, Ulrich ^ae,ca   Schubert, Christian R ^dw   Schulze, Thomas G ^bo,dx   Schwab, Sibylle G ^dy   Scolnick, Edward M ^b   Scott, Rodney J ^ae,ca,dz   Seidman, Larry J ^cc,dc   Shi, Jianxin ^ea   Sigurdsson, Engilbert ^eb   Silagadze, Teimuraz ^ec   Silverman, Jeremy M ^ab,bn   Sim, Kang ^am   Slominsky, Petr ^cn   Smoller, Jordan W ^a,b   So, Hon Cheong ^ai   Spencer, Chris C A ^ed   Stahl, Eli A ^b,ab   Stefansson, Hreinn ^ee   Steinberg, Stacy ^ee   Stogmann, Elisabeth ^ef   Straub, Richard E ^eg   Strengman, Eric ^aa   Strohmaier, Jana ^bo   Stroup, T Scott ^cx   Subramaniam, Mythily ^am   Suvisaari, Jaana ^bi   Svrakic, Dragan M ^an   Szatkiewicz, Jin P ^aq   Söderman, Erik ^j   Thirumalai, Srinivas ^eh   Toncheva, Draga ^ci   Tosato, Sarah ^ei   Veijola, Juha ^ej,ek   Waddington, John ^df   Walsh, Dermot ^el   Wang, Dai ^bv   Wang, Qiang ^cv   Webb, Bradley T ^s   Weiser, Mark ^at   Wildenauer, Dieter B ^ch   Williams, Nigel M ^d   Williams, Stephanie ^aq   Witt, Stephanie H ^bo   Wolen, Aaron R ^s   Wong, Emily H M ^ai   Wormley, Brandon K ^s   Xi, Hualin Simon ^dw   Zai, Clement C ^ck,cl   Zheng, Xuebin ^em   Zimprich, Fritz ^ef   Wray, Naomi R ^ag   Stefansson, Kari ^ee   Visscher, Peter M ^ag,en   Adolfsson, Rolf ^dm   Andreassen, Ole A ^l,az   Blackwood, Douglas H R ^db   Bramon, Elvira ^as   Buxbaum, Joseph D ^ab   Børglum, Anders D ^m,n,de   Cichon, Sven ^au,av,cb,eo   Darvasi, Ariel ^ep   Domenici, Enrico ^eq   Ehrenreich, Hannelore ^t   Esko, Tõnu ^b,i,cc,dd   Gejman, Pablo V ^bb,bc   Gill, Michael ^c   Gurling, Hugh ^as   Hultman, Christina M ^j   Iwata, Nakao ^ce   Jablensky, Assen V ^ae,ch,er   Jönsson, Erik G ^j,l   Kendler, Kenneth S ^s   Kirov, George ^d   Knight, Jo ^ck,cl,cm   Lencz, Todd ^es,et,eu   Levinson, Douglas F ^p   Li, Qingqin S ^bv   Liu, Jianjun ^em,ev   Malhotra, Anil K ^es,et,eu   McCarroll, Steven A ^b,cc   McQuillin, Andrew ^as   Moran, Jennifer L ^b   Mortensen, Preben B ^m,n   Mowry, Bryan J ^ag   Nöthen, Markus M ^au,av   Ophoff, Roel A ^aa,ad,bq   Owen, Michael J ^d,e   Palotie, Aarno ^a,b,ds   Pato, Carlos N ^bl   Petryshen, Tracey L ^a,b,cc   Posthuma, Danielle ^ew,ex,ey   Rietschel, Marcella ^bo   Riley, Brien P ^s   Rujescu, Dan ^br,bs   Sham, Pak C ^ai,aj,cu   Sklar, Pamela ^ab   St Clair, David ^ez   Weinberger, Daniel R ^dl,eg   Wendland, Jens R ^dw   Werge, Thomas ^n,by,fa   Daly, Mark J ^a,b   Sullivan, Patrick F ^j,aq   O'Donovan, Michael C ^d,e   more..

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d Cardiff University   (United Kingdom)

^e CARDIFF UNIVERSITY   (United Kingdom)

^f ELI LILLY AND COMPANY   (United States)

^g KING'S COLLEGE LONDON   (United Kingdom)

^h TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

ⁱ BOSTON CHILDREN S HOSPITAL   (United States)

^j KAROLINSKA INSTITUTE   (Sweden)

^k DIAKONHJEMMET HOSPITAL   (Norway)

^l UNIVERSITY OF OSLO   (Norway)

^m AARHUS UNIVERSITY   (Denmark)

ⁿ Aarhus   (Denmark)

^o KLINIKUM MÜNCHEN OST   (Germany)

^p STANFORD UNIVERSITY   (United States)

^q ATLANTA VA MEDICAL CENTER   (United States)

^r EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^s VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^t MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

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^v UNIVERSITY OF IOWA   (United States)

^w UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

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^ab MOUNT SINAI SCHOOL OF MEDICINE   (United States)

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^ad UNIVERSITY OF CALIFORNIA   (United States)

^ae SCHIZOPHRENIA RESEARCH INSTITUTE   (Australia)

^af UNIVERSITY OF NEW SOUTH WALES   (Australia)

^ag UNIVERSITY OF QUEENSLAND   (Australia)

^ah INSTITUTE OF PSYCHOLOGY   (China)

^ai UNIVERSITY OF HONG KONG   (Hong Kong)

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^ak CB 3175 Sitterson Hall   (United States)

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^ao ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^ap Blue Note Biosciences   (United States)

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^at SHEBA MEDICAL CENTER   (Israel)

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^ax UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^ay UNIVERSITY COLLEGE CORK   (Ireland)

^az OSLO UNIVERSITY HOSPITAL   (Norway)

^ba NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^bb UNIVERSITY OF CHICAGO   (United States)

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^bd LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^be University Clinic of Psychiatry   (Macedonia)

^bf UNIVERSITY OF REGENSBURG   (Germany)

^bg HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^bh FOLKHÄLSAN RESEARCH CENTER   (Finland)

^bi NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^bj Translational Technologies and Bioinformatics Pharma Research and Early Development   (Switzerland)

^bk GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bl UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^bm VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

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^bo UNIVERSITY OF HEIDELBERG   (Germany)

^bp UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^bq UNIVERSITY OF CALIFORNIA   (United States)

^br MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^bs UNIVERSITY OF MUNICH   (Germany)

^bt PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^bu MENTAL HEALTH RESEARCH CENTER   (Russian Federation)

^bv JANSSEN RESEARCH AND DEVELOPMENT   (United States)

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^bx ILLUMINA INC   (United States)

^by Mental Health Centre Sct Hans   (Denmark)

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^cq UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

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^dc BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

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^df ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

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^dh UNIVERSITY OF LIVERPOOL   (United Kingdom)

^di MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^dj Department of Psychiatry Hadassah Hebrew University Medical Center ^*  (Germany)

^dk JENA UNIVERSITY HOSPITAL   (Germany)

^dl JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^dm UMEÅ UNIVERSITY   (Sweden)

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^dt UNIVERSITY OF BELGRADE   (Serbia)

^du HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

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^dy UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

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^eb UNIVERSITY OF ICELAND   (Iceland)

^ec TBILISI STATE MEDICAL UNIVERSITY   (Georgia)

^ed UNIVERSITY OF OXFORD   (United Kingdom)

^ee DECODE GENETICS   (Iceland)

^ef MEDICAL UNIVERSITY OF VIENNA   (Austria)

^eg LIEBER INSTITUTE FOR BRAIN DEVELOPMENT   (United States)

^eh BERKSHIRE HEALTHCARE NHS FOUNDATION TRUST   (United Kingdom)

^ei UNIVERSITY OF VERONA   (Italy)

^ej UNIVERSITY OF OULU   (Finland)

^ek OULU UNIVERSITY HOSPITAL   (Finland)

^el HEALTH RESEARCH BOARD   (Ireland)

^em GENOME INSTITUTE OF SINGAPORE   (Singapore)

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^eo FORSCHUNGSZENTRUM JÜLICH   (Germany)

^ep HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^eq F Hoffmann La Roche   (Switzerland)

^er UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^es FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^et DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

^eu ZUCKER HILLSIDE HOSPITAL   (United States)

^ev NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^ew ERASMUS MEDICAL CENTER   (Netherlands)

^ex VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^ey VU UNIVERSITY AMSTERDAM   (Netherlands)

^ez UNIVERSITY OF ABERDEEN   (United Kingdom)

^fa UNIVERSITY OF COPENHAGEN   (Denmark)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 2 RECEPTOR;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; IMMUNE SYSTEM; IMMUNITY; MAJOR CLINICAL STUDY; NEUROTRANSMISSION; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; BRAIN; ENHANCER ELEMENTS, GENETIC; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GLUTAMIC ACID; HUMANS; IMMUNITY; MULTIFACTORIAL INHERITANCE; MUTATION; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; SCHIZOPHRENIA; SYNAPTIC TRANSMISSION;

EID: 84904804929     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13595     Document Type: Article

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