Human embryonic stem cell-derived oligodendrocyte progenitors remyelinate the brain and rescue behavioral deficits following radiation

Cell Stem Cell

Volumn 16, Issue 2, 2015, Pages 198-210

  Piao, Jinghua ^a   Major, Tamara ^a   Auyeung, Gordon ^a   Policarpio, Edelweiss ^a   Menon, Jayanthi ^a   Droms, Leif ^a   Gutin, Philip ^a   Uryu, Kunihiro ^b   Tchieu, Jason ^a   Soulet, Denis ^c,d   Tabar, Viviane ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITÉ LAVAL   (Canada)

^d Université Laval   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 11; MYELIN; MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN BASIC PROTEIN; NERVE CELL ADHESION MOLECULE; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR SOX10;

ANIMAL EXPERIMENT; ARTICLE; BRAIN CORTEX; BRAIN RADIATION; CANCER SURVIVOR; CEREBELLUM; COGNITION; CONTROLLED STUDY; CORPUS CALLOSUM; DEMYELINATION; EMBRYONIC STEM CELL DERIVED OLIGODENDROCYTE; EMBRYONIC STEM CELL DERIVED OLIGODENDROCYTE TRANSPLANTATION; HIPPOCAMPAL FIMBRIA; IMMUNOHISTOCHEMISTRY; MYELINATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RADIATION INJURY; RAT; STEM CELL; STEM CELL TRANSPLANTATION; ANIMAL; BRAIN; COGNITION DISORDERS; CYTOLOGY; DISEASE MODEL; FEMALE; HUMAN; HUMAN EMBRYONIC STEM CELL; METABOLISM; MYELIN SHEATH; NUDE RAT; PATHOPHYSIOLOGY; RADIATION RESPONSE; TRANSPLANTATION; X RAY;

RATTUS;

ANIMALS; BRAIN; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; FEMALE; HUMAN EMBRYONIC STEM CELLS; HUMANS; MYELIN SHEATH; OLIGODENDROGLIA; RATS; RATS, NUDE; X-RAYS;

EID: 84924905197     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2015.01.004     Document Type: Article

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