Synaptic dysregulation in a human iPS cell model of mental disorders

Nature

Volumn 515, Issue 7527, 2014, Pages 414-418

  Wen, Zhexing ^a   Nguyen, Ha Nam ^a   Guo, Ziyuan ^b   Lalli, Matthew A ^c   Wang, Xinyuan ^a,d   Su, Yijing ^a   Kim, Nam Shik ^a   Yoon, Ki Jun ^a   Shin, Jaehoon ^a   Zhang, Ce ^a   Makri, Georgia ^a   Nauen, David ^a   Yu, Huimei ^a   Guzman, Elmer ^c   Chiang, Cheng Hsuan ^a   Yoritomo, Nadine ^a   Kaibuchi, Kozo ^e   Zou, Jizhong ^a   Christian, Kimberly M ^a   Cheng, Linzhao ^a   Ross, Christopher A ^a   Margolis, Russell L ^a   Chen, Gong ^b   Kosik, Kenneth S ^c   Song, Hongjun ^a   Ming, Guo Li ^a   more..

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d FUDAN UNIVERSITY   (China)

^e NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; GLUTAMATE DECARBOXYLASE 67; TRANSCRIPTION FACTOR EMX1; TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR PAX6; VESICULAR GLUTAMATE TRANSPORTER 1; DISC1 PROTEIN, HUMAN; GLUTAMINE; MUTANT PROTEIN; NERVE PROTEIN; PROTEIN BINDING; TRANSCRIPTOME;

BRAIN; ETIOLOGY; GENE EXPRESSION; MENTAL HEALTH; MOLECULAR ANALYSIS; NERVOUS SYSTEM DISORDER; NEUROLOGY; PSYCHOLOGY;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; FOREBRAIN; FRAMESHIFT MUTATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MENTAL DISEASE; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PLURIPOTENT STEM CELL; SYNAPSE; SYNAPSE VESICLE; ANIMAL; CYTOLOGY; FIBROBLAST; GENETICS; MALE; METABOLISM; MUTATION; NERVE CELL; PATHOLOGY; PEDIGREE; SYNAPTOSOME;

IPS;

ANIMALS; CELL DIFFERENTIATION; FIBROBLASTS; GLUTAMINE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MALE; MENTAL DISORDERS; MICE; MUTANT PROTEINS; MUTATION; NERVE TISSUE PROTEINS; NEURONS; PEDIGREE; PRESYNAPTIC TERMINALS; PROSENCEPHALON; PROTEIN BINDING; SYNAPSES; TRANSCRIPTOME;

EID: 84911360325     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13716     Document Type: Article

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