Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder

Cell Reports

Volumn 21, Issue 10, 2017, Pages 2678-2687

  Deshpande, Aditi ^a,b   Yadav, Smita ^a,b   Dao, Dang Q ^b   Wu, Zhi Yong ^a,b   Hokanson, Kenton C ^a,b   Cahill, Michelle K ^a   Wiita, Arun P ^b   Jan, Yuh Nung ^a,b   Ullian, Erik M ^a,b   Weiss, Lauren A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

16p11.2 CNV; autism; deletion; duplication; iPSC; macrocephaly; microcephaly; neurodevelopmental disorders; neurons

Indexed keywords

ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN SIZE; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL PROLIFERATION; CELL SIZE; CONNECTOME; CONTROLLED STUDY; DENDRITE; ELECTROPHYSIOLOGY; FIBROBLAST; GENETIC MODEL; HUMAN; HUMAN CELL; INDUCED PLURIPOTENT STEM CELL; MORPHOLOGY; MOUSE; NERVE CELL; NEUROBIOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; ALEXANDER DISEASE; BIOLOGICAL MODEL; CHROMOSOME 16; CHROMOSOME DELETION; CHROMOSOME DUPLICATION; COPY NUMBER VARIATION; CYTOLOGY; GENETICS; METABOLISM; MICROCEPHALY; PHYSIOLOGY;

AUTISM SPECTRUM DISORDER; AUTISTIC DISORDER; CELL DIFFERENTIATION; CHROMOSOME DELETION; CHROMOSOME DUPLICATION; CHROMOSOMES, HUMAN, PAIR 16; DNA COPY NUMBER VARIATIONS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MEGALENCEPHALY; MICROCEPHALY; MODELS, GENETIC; NEURONS;

EID: 85038113589     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.11.037     Document Type: Article

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