-
1
-
-
84955055595
-
Emerging roles of the mineralocorticoid receptor in pathology: toward new paradigms in clinical pharmacology
-
Jaisser, F., Farman, N., Emerging roles of the mineralocorticoid receptor in pathology: toward new paradigms in clinical pharmacology. Pharmacol Rev 68 (2016), 49–75.
-
(2016)
Pharmacol Rev
, vol.68
, pp. 49-75
-
-
Jaisser, F.1
Farman, N.2
-
2
-
-
44949169677
-
Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion
-
Caprio, M., Newfell, B.G., la Sala, A., et al. Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion. Circ Res 102 (2008), 1359–1367.
-
(2008)
Circ Res
, vol.102
, pp. 1359-1367
-
-
Caprio, M.1
Newfell, B.G.2
la Sala, A.3
-
3
-
-
84921795795
-
Myeloid mineralocorticoid receptor activation contributes to progressive kidney disease
-
Huang, L.L., Nikolic-Paterson, D.J., Han, Y., et al. Myeloid mineralocorticoid receptor activation contributes to progressive kidney disease. J Am Soc Nephrol 25 (2014), 2231–2240.
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 2231-2240
-
-
Huang, L.L.1
Nikolic-Paterson, D.J.2
Han, Y.3
-
4
-
-
20144365498
-
Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability
-
Nishiyama, A., Yao, L., Fan, Y., et al. Involvement of aldosterone and mineralocorticoid receptors in rat mesangial cell proliferation and deformability. Hypertension 45 (2005), 710–716.
-
(2005)
Hypertension
, vol.45
, pp. 710-716
-
-
Nishiyama, A.1
Yao, L.2
Fan, Y.3
-
5
-
-
31544477239
-
Aldosterone stimulates collagen gene expression and synthesis via activation of ERK1/2 in rat renal fibroblasts
-
Nagai, Y., Miyata, K., Sun, G.P., et al. Aldosterone stimulates collagen gene expression and synthesis via activation of ERK1/2 in rat renal fibroblasts. Hypertension 46 (2005), 1039–1045.
-
(2005)
Hypertension
, vol.46
, pp. 1039-1045
-
-
Nagai, Y.1
Miyata, K.2
Sun, G.P.3
-
6
-
-
70349257487
-
Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure
-
Rickard, A.J., Morgan, J., Tesch, G., et al. Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure. Hypertension 54 (2009), 537–543.
-
(2009)
Hypertension
, vol.54
, pp. 537-543
-
-
Rickard, A.J.1
Morgan, J.2
Tesch, G.3
-
7
-
-
77956388193
-
Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice
-
Usher, M.G., Duan, S.Z., Ivaschenko, C.Y., et al. Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice. J Clin Invest 120 (2010), 3350–3364.
-
(2010)
J Clin Invest
, vol.120
, pp. 3350-3364
-
-
Usher, M.G.1
Duan, S.Z.2
Ivaschenko, C.Y.3
-
8
-
-
85015710092
-
T-cell mineralocorticoid receptor controls blood pressure by regulating interferon-gamma
-
Sun, X.N., Li, C., Liu, Y., et al. T-cell mineralocorticoid receptor controls blood pressure by regulating interferon-gamma. Circ Res 120 (2017), 1584–1597.
-
(2017)
Circ Res
, vol.120
, pp. 1584-1597
-
-
Sun, X.N.1
Li, C.2
Liu, Y.3
-
9
-
-
0023715656
-
Parallel determination of mineralocorticoid and glucocorticoid receptors in T- and B-lymphocytes of human spleen
-
Armanini, D., Endres, S., Kuhnle, U., Weber, P.C., Parallel determination of mineralocorticoid and glucocorticoid receptors in T- and B-lymphocytes of human spleen. Acta Endocrinol (Copenh) 118 (1988), 479–482.
-
(1988)
Acta Endocrinol (Copenh)
, vol.118
, pp. 479-482
-
-
Armanini, D.1
Endres, S.2
Kuhnle, U.3
Weber, P.C.4
-
10
-
-
78649949044
-
In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule
-
Ackermann, D., Gresko, N., Carrel, M., et al. In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule. Am J Physiol Renal Physiol 299 (2010), F1473–F1485.
-
(2010)
Am J Physiol Renal Physiol
, vol.299
, pp. F1473-F1485
-
-
Ackermann, D.1
Gresko, N.2
Carrel, M.3
-
11
-
-
77954434421
-
The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure
-
Nguyen Dinh Cat, A., Griol-Charhbili, V., Loufrani, L., et al. The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure. FASEB J 24 (2010), 2454–2463.
-
(2010)
FASEB J
, vol.24
, pp. 2454-2463
-
-
Nguyen Dinh Cat, A.1
Griol-Charhbili, V.2
Loufrani, L.3
-
12
-
-
16444375794
-
Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells
-
Jaffe, I.Z., Mendelsohn, M.E., Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells. Circ Res 96 (2005), 643–650.
-
(2005)
Circ Res
, vol.96
, pp. 643-650
-
-
Jaffe, I.Z.1
Mendelsohn, M.E.2
-
13
-
-
28444456990
-
Aldosterone stimulates proliferation of mesangial cells by activating mitogen-activated protein kinase 1/2, cyclin D1, and cyclin A
-
Terada, Y., Kobayashi, T., Kuwana, H., et al. Aldosterone stimulates proliferation of mesangial cells by activating mitogen-activated protein kinase 1/2, cyclin D1, and cyclin A. J Am Soc Nephrol 16 (2005), 2296–2305.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2296-2305
-
-
Terada, Y.1
Kobayashi, T.2
Kuwana, H.3
-
14
-
-
34547670265
-
Glucocorticoids exert opposing effects on macrophage function dependent on their concentration
-
Lim, H.Y., Muller, N., Herold, M.J., et al. Glucocorticoids exert opposing effects on macrophage function dependent on their concentration. Immunology 122 (2007), 47–53.
-
(2007)
Immunology
, vol.122
, pp. 47-53
-
-
Lim, H.Y.1
Muller, N.2
Herold, M.J.3
-
15
-
-
33744958894
-
Local amplification of glucocorticoids by 11 beta-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes
-
Gilmour, J.S., Coutinho, A.E., Cailhier, J.F., et al. Local amplification of glucocorticoids by 11 beta-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes. J Immunol 176 (2006), 7605–7611.
-
(2006)
J Immunol
, vol.176
, pp. 7605-7611
-
-
Gilmour, J.S.1
Coutinho, A.E.2
Cailhier, J.F.3
-
16
-
-
33846963787
-
Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity
-
Leopold, J.A., Dam, A., Maron, B.A., et al. Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity. Nat Med 13 (2007), 189–197.
-
(2007)
Nat Med
, vol.13
, pp. 189-197
-
-
Leopold, J.A.1
Dam, A.2
Maron, B.A.3
-
17
-
-
84865214267
-
Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension
-
Maron, B.A., Zhang, Y.Y., White, K., et al. Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension. Circulation 126 (2012), 963–974.
-
(2012)
Circulation
, vol.126
, pp. 963-974
-
-
Maron, B.A.1
Zhang, Y.Y.2
White, K.3
-
18
-
-
79959404155
-
Spironolactone inhibits NADPH oxidase-induced oxidative stress and enhances eNOS in human endothelial cells
-
Taye, A., Morawietz, H., Spironolactone inhibits NADPH oxidase-induced oxidative stress and enhances eNOS in human endothelial cells. Iran J Pharm Res 10 (2011), 329–337.
-
(2011)
Iran J Pharm Res
, vol.10
, pp. 329-337
-
-
Taye, A.1
Morawietz, H.2
-
19
-
-
15744377168
-
Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src
-
Callera, G.E., Touyz, R.M., Tostes, R.C., et al. Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src. Hypertension 45 (2005), 773–779.
-
(2005)
Hypertension
, vol.45
, pp. 773-779
-
-
Callera, G.E.1
Touyz, R.M.2
Tostes, R.C.3
-
20
-
-
33846443625
-
Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1
-
Shibata, S., Nagase, M., Yoshida, S., et al. Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1. Hypertension 49 (2007), 355–364.
-
(2007)
Hypertension
, vol.49
, pp. 355-364
-
-
Shibata, S.1
Nagase, M.2
Yoshida, S.3
-
21
-
-
31544473558
-
Aldosterone stimulates reactive oxygen species production through activation of NADPH oxidase in rat mesangial cells
-
Miyata, K., Rahman, M., Shokoji, T., et al. Aldosterone stimulates reactive oxygen species production through activation of NADPH oxidase in rat mesangial cells. J Am Soc Nephrol 16 (2005), 2906–2912.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2906-2912
-
-
Miyata, K.1
Rahman, M.2
Shokoji, T.3
-
22
-
-
49949102889
-
Aldosterone induces mesangial cell apoptosis both in vivo and in vitro
-
Mathew, J.T., Patni, H., Chaudhary, A.N., et al. Aldosterone induces mesangial cell apoptosis both in vivo and in vitro. Am J Physiol Renal Physiol 295 (2008), F73–F81.
-
(2008)
Am J Physiol Renal Physiol
, vol.295
, pp. F73-F81
-
-
Mathew, J.T.1
Patni, H.2
Chaudhary, A.N.3
-
23
-
-
56549093414
-
Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells
-
Diah, S., Zhang, G.X., Nagai, Y., et al. Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells. Exp Cell Res 314 (2008), 3654–3662.
-
(2008)
Exp Cell Res
, vol.314
, pp. 3654-3662
-
-
Diah, S.1
Zhang, G.X.2
Nagai, Y.3
-
24
-
-
0028275578
-
Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone
-
Brilla, C.G., Zhou, G., Matsubara, L., Weber, K.T., Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone. J Mol Cell Cardiol 26 (1994), 809–820.
-
(1994)
J Mol Cell Cardiol
, vol.26
, pp. 809-820
-
-
Brilla, C.G.1
Zhou, G.2
Matsubara, L.3
Weber, K.T.4
-
25
-
-
0030031393
-
Effects of angiotensin II and aldosterone on collagen gene expression and protein turnover in cardiac fibroblasts
-
Zhou, G., Kandala, J.C., Tyagi, S.C., et al. Effects of angiotensin II and aldosterone on collagen gene expression and protein turnover in cardiac fibroblasts. Mol Cell Biochem 154 (1996), 171–178.
-
(1996)
Mol Cell Biochem
, vol.154
, pp. 171-178
-
-
Zhou, G.1
Kandala, J.C.2
Tyagi, S.C.3
-
26
-
-
38549147471
-
Osteopontin in rat renal fibroblasts: functional properties and transcriptional regulation by aldosterone
-
Irita, J., Okura, T., Kurata, M., et al. Osteopontin in rat renal fibroblasts: functional properties and transcriptional regulation by aldosterone. Hypertension 51 (2008), 507–513.
-
(2008)
Hypertension
, vol.51
, pp. 507-513
-
-
Irita, J.1
Okura, T.2
Kurata, M.3
-
27
-
-
1942472591
-
Effect of aldosterone and glycyrrhetinic acid on the protein expression of PAI-1 and p22(phox) in human mononuclear leukocytes
-
Calo, L.A., Zaghetto, F., Pagnin, E., et al. Effect of aldosterone and glycyrrhetinic acid on the protein expression of PAI-1 and p22(phox) in human mononuclear leukocytes. J Clin Endocrinol Metab 89 (2004), 1973–1976.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1973-1976
-
-
Calo, L.A.1
Zaghetto, F.2
Pagnin, E.3
-
28
-
-
85040021182
-
Neutrophil gelatinase-associated lipocalin from immune cells is mandatory for aldosterone-induced cardiac remodeling and inflammation
-
Buonafine, M., Martinez-Martinez, E., Amador, C., et al. Neutrophil gelatinase-associated lipocalin from immune cells is mandatory for aldosterone-induced cardiac remodeling and inflammation. J Mol Cell Cardiol 115 (2018), 32–38.
-
(2018)
J Mol Cell Cardiol
, vol.115
, pp. 32-38
-
-
Buonafine, M.1
Martinez-Martinez, E.2
Amador, C.3
-
29
-
-
85023206564
-
30 years of the mineralocorticoid receptor: mineralocorticoid receptor null mice: informing cell-type-specific roles
-
Cole, T.J., Young, M.J., 30 years of the mineralocorticoid receptor: mineralocorticoid receptor null mice: informing cell-type-specific roles. J Endocrinol 234 (2017), T83–T92.
-
(2017)
J Endocrinol
, vol.234
, pp. T83-T92
-
-
Cole, T.J.1
Young, M.J.2
-
30
-
-
47549114629
-
Spironolactone exhibits direct renoprotective effects and inhibits renal renin-angiotensin-aldosterone system in diabetic rats
-
Taira, M., Toba, H., Murakami, M., et al. Spironolactone exhibits direct renoprotective effects and inhibits renal renin-angiotensin-aldosterone system in diabetic rats. Eur J Pharmacol 589 (2008), 264–271.
-
(2008)
Eur J Pharmacol
, vol.589
, pp. 264-271
-
-
Taira, M.1
Toba, H.2
Murakami, M.3
-
31
-
-
24744454626
-
Increased expression of mineralocorticoid effector mechanisms in kidney biopsies of patients with heavy proteinuria
-
Quinkler, M., Zehnder, D., Eardley, K.S., et al. Increased expression of mineralocorticoid effector mechanisms in kidney biopsies of patients with heavy proteinuria. Circulation 112 (2005), 1435–1443.
-
(2005)
Circulation
, vol.112
, pp. 1435-1443
-
-
Quinkler, M.1
Zehnder, D.2
Eardley, K.S.3
-
32
-
-
77952958303
-
Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent pathways
-
Krug, A.W., Allenhofer, L., Monticone, R., et al. Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent pathways. Hypertension 55 (2010), 1476–1483.
-
(2010)
Hypertension
, vol.55
, pp. 1476-1483
-
-
Krug, A.W.1
Allenhofer, L.2
Monticone, R.3
-
33
-
-
3142776828
-
Enhancement of glucocorticoid and mineralocorticoid receptor density in the microcirculation of the spontaneously hypertensive rat
-
DeLano, F.A., Schmid-Schonbein, G.W., Enhancement of glucocorticoid and mineralocorticoid receptor density in the microcirculation of the spontaneously hypertensive rat. Microcirculation 11 (2004), 69–78.
-
(2004)
Microcirculation
, vol.11
, pp. 69-78
-
-
DeLano, F.A.1
Schmid-Schonbein, G.W.2
-
34
-
-
85023173577
-
30 years of the mineralocorticoid receptor: Mineralocorticoid receptor antagonists: 60 years of research and development
-
Kolkhof, P., Barfacker, L., 30 years of the mineralocorticoid receptor: Mineralocorticoid receptor antagonists: 60 years of research and development. J Endocrinol 234 (2017), T125–T140.
-
(2017)
J Endocrinol
, vol.234
, pp. T125-T140
-
-
Kolkhof, P.1
Barfacker, L.2
-
35
-
-
84942608331
-
Nonsteroidal antagonists of the mineralocorticoid receptor
-
Kolkhof, P., Nowack, C., Eitner, F., Nonsteroidal antagonists of the mineralocorticoid receptor. Curr Opin Nephrol Hypertens 24 (2015), 417–424.
-
(2015)
Curr Opin Nephrol Hypertens
, vol.24
, pp. 417-424
-
-
Kolkhof, P.1
Nowack, C.2
Eitner, F.3
-
36
-
-
34548012161
-
Renal ischemia-reperfusion injury is prevented by the mineralocorticoid receptor blocker spironolactone
-
Mejía-Vilet, J.M., Ramirez, V., Cruz, C., et al. Renal ischemia-reperfusion injury is prevented by the mineralocorticoid receptor blocker spironolactone. Am J Physiol Renal Physiol 293 (2007), F78–F86.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. F78-F86
-
-
Mejía-Vilet, J.M.1
Ramirez, V.2
Cruz, C.3
-
37
-
-
70349633480
-
Adrenalectomy prevents renal ischemia-reperfusion injury
-
Ramirez, V., Trujillo, J., Valdes, R., et al. Adrenalectomy prevents renal ischemia-reperfusion injury. Am J Physiol Renal Physiol 297 (2009), F932–F942.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F932-F942
-
-
Ramirez, V.1
Trujillo, J.2
Valdes, R.3
-
38
-
-
84864585183
-
Recovery from ischemic acute kidney injury by spironolactone administration
-
Sanchez-Pozos, K., Barrera-Chimal, J., Garzon-Muvdi, J., et al. Recovery from ischemic acute kidney injury by spironolactone administration. Nephrol Dial Transplant 27 (2012), 3160–3169.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 3160-3169
-
-
Sanchez-Pozos, K.1
Barrera-Chimal, J.2
Garzon-Muvdi, J.3
-
39
-
-
84970925334
-
Sulfenic acid modification of endothelin B receptor is responsible for the benefit of a nonsteroidal mineralocorticoid receptor antagonist in renal ischemia
-
Barrera-Chimal, J., Prince, S., Fadel, F., et al. Sulfenic acid modification of endothelin B receptor is responsible for the benefit of a nonsteroidal mineralocorticoid receptor antagonist in renal ischemia. J Am Soc Nephrol 27 (2016), 398–404.
-
(2016)
J Am Soc Nephrol
, vol.27
, pp. 398-404
-
-
Barrera-Chimal, J.1
Prince, S.2
Fadel, F.3
-
40
-
-
85015807935
-
Nonsteroidal mineralocorticoid receptor antagonist finerenone protects against acute kidney injury-mediated chronic kidney disease: role of oxidative stress
-
Lattenist, L., Lechner, S.M., Messaoudi, S., et al. Nonsteroidal mineralocorticoid receptor antagonist finerenone protects against acute kidney injury-mediated chronic kidney disease: role of oxidative stress. Hypertension 69 (2017), 870–878.
-
(2017)
Hypertension
, vol.69
, pp. 870-878
-
-
Lattenist, L.1
Lechner, S.M.2
Messaoudi, S.3
-
41
-
-
85021661134
-
Benefit of mineralocorticoid receptor antagonism in AKI: role of vascular smooth muscle Rac1
-
Barrera-Chimal, J., Andre-Gregoire, G., Nguyen Dinh Cat, A., et al. Benefit of mineralocorticoid receptor antagonism in AKI: role of vascular smooth muscle Rac1. J Am Soc Nephrol 28 (2017), 1216–1226.
-
(2017)
J Am Soc Nephrol
, vol.28
, pp. 1216-1226
-
-
Barrera-Chimal, J.1
Andre-Gregoire, G.2
Nguyen Dinh Cat, A.3
-
42
-
-
84908246474
-
Pretreatment with mineralocorticoid receptor blocker reduces intestinal injury induced by ischemia and reperfusion: involvement of inhibition of inflammatory response, oxidative stress, nuclear factor kappaB, and inducible nitric oxide synthase
-
Ozacmak, H.S., Ozacmak, V.H., Barut, F., et al. Pretreatment with mineralocorticoid receptor blocker reduces intestinal injury induced by ischemia and reperfusion: involvement of inhibition of inflammatory response, oxidative stress, nuclear factor kappaB, and inducible nitric oxide synthase. J Surg Res 191 (2014), 350–361.
-
(2014)
J Surg Res
, vol.191
, pp. 350-361
-
-
Ozacmak, H.S.1
Ozacmak, V.H.2
Barut, F.3
-
43
-
-
47949093291
-
The role of mineralocorticoid receptor expression in brain remodeling after cerebral ischemia
-
Oyamada, N., Sone, M., Miyashita, K., et al. The role of mineralocorticoid receptor expression in brain remodeling after cerebral ischemia. Endocrinology 149 (2008), 3764–3777.
-
(2008)
Endocrinology
, vol.149
, pp. 3764-3777
-
-
Oyamada, N.1
Sone, M.2
Miyashita, K.3
-
44
-
-
33749354007
-
Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure
-
Kang, Y.M., Zhang, Z.H., Johnson, R.F., et al. Novel effect of mineralocorticoid receptor antagonism to reduce proinflammatory cytokines and hypothalamic activation in rats with ischemia-induced heart failure. Circ Res 99 (2006), 758–766.
-
(2006)
Circ Res
, vol.99
, pp. 758-766
-
-
Kang, Y.M.1
Zhang, Z.H.2
Johnson, R.F.3
-
45
-
-
85051975343
-
Acute kidney injury to chronic kidney disease transition
-
Fiorentino, M., Grandaliano, G., Gesualdo, L., Castellano, G., Acute kidney injury to chronic kidney disease transition. Contrib Nephrol 193 (2018), 45–54.
-
(2018)
Contrib Nephrol
, vol.193
, pp. 45-54
-
-
Fiorentino, M.1
Grandaliano, G.2
Gesualdo, L.3
Castellano, G.4
-
46
-
-
84871765500
-
Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury
-
Barrera-Chimal, J., Perez-Villalva, R., Rodriguez-Romo, R., et al. Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury. Kidney Int 83 (2013), 93–103.
-
(2013)
Kidney Int
, vol.83
, pp. 93-103
-
-
Barrera-Chimal, J.1
Perez-Villalva, R.2
Rodriguez-Romo, R.3
-
47
-
-
85083070642
-
Delayed spironolactone administration prevents the transition from acute kidney injury to chronic kidney disease through improving renal inflammation
-
Barrera-Chimal, J., Rocha, L., Amador-Martinez, I., et al. Delayed spironolactone administration prevents the transition from acute kidney injury to chronic kidney disease through improving renal inflammation. Nephrol Dial Transplant, 2018.
-
(2018)
Nephrol Dial Transplant
-
-
Barrera-Chimal, J.1
Rocha, L.2
Amador-Martinez, I.3
-
48
-
-
84933514504
-
Mild ischemic injury leads to long-term alterations in the kidney: amelioration by spironolactone administration
-
Barrera-Chimal, J., Perez-Villalva, R., Ortega, J.A., et al. Mild ischemic injury leads to long-term alterations in the kidney: amelioration by spironolactone administration. Int J Biol Sci 11 (2015), 892–900.
-
(2015)
Int J Biol Sci
, vol.11
, pp. 892-900
-
-
Barrera-Chimal, J.1
Perez-Villalva, R.2
Ortega, J.A.3
-
49
-
-
84880520852
-
Myeloid mineralocorticoid receptor during experimental ischemic stroke: effects of model and sex
-
Frieler, R.A., Ray, J.J., Meng, H., et al. Myeloid mineralocorticoid receptor during experimental ischemic stroke: effects of model and sex. J Am Heart Assoc, 1, 2012, e002584.
-
(2012)
J Am Heart Assoc
, vol.1
, pp. e002584
-
-
Frieler, R.A.1
Ray, J.J.2
Meng, H.3
-
50
-
-
79451472879
-
Myeloid-specific deletion of the mineralocorticoid receptor reduces infarct volume and alters inflammation during cerebral ischemia
-
Frieler, R.A., Meng, H., Duan, S.Z., et al. Myeloid-specific deletion of the mineralocorticoid receptor reduces infarct volume and alters inflammation during cerebral ischemia. Stroke 42 (2011), 179–185.
-
(2011)
Stroke
, vol.42
, pp. 179-185
-
-
Frieler, R.A.1
Meng, H.2
Duan, S.Z.3
-
51
-
-
84982843312
-
Cardiac tissue injury and remodeling is dependent upon MR regulation of activation pathways in cardiac tissue macrophages
-
Shen, J.Z., Morgan, J., Tesch, G.H., et al. Cardiac tissue injury and remodeling is dependent upon MR regulation of activation pathways in cardiac tissue macrophages. Endocrinology 157 (2016), 3213–3223.
-
(2016)
Endocrinology
, vol.157
, pp. 3213-3223
-
-
Shen, J.Z.1
Morgan, J.2
Tesch, G.H.3
-
52
-
-
84908538419
-
Myeloid mineralocorticoid receptor deficiency inhibits aortic constriction-induced cardiac hypertrophy in mice
-
Li, C., Zhang, Y.Y., Frieler, R.A., et al. Myeloid mineralocorticoid receptor deficiency inhibits aortic constriction-induced cardiac hypertrophy in mice. PLoS One, 9, 2014, e110950.
-
(2014)
PLoS One
, vol.9
, pp. e110950
-
-
Li, C.1
Zhang, Y.Y.2
Frieler, R.A.3
-
53
-
-
84907612321
-
Cardiac macrophages and apoptosis after myocardial infarction: effects of central MR blockade
-
Rafatian, N., Westcott, K.V., White, R.A., Leenen, F.H., Cardiac macrophages and apoptosis after myocardial infarction: effects of central MR blockade. Am J Physiol Regul Integr Comp Physiol 307 (2014), R879–R887.
-
(2014)
Am J Physiol Regul Integr Comp Physiol
, vol.307
, pp. R879-R887
-
-
Rafatian, N.1
Westcott, K.V.2
White, R.A.3
Leenen, F.H.4
-
54
-
-
0029810416
-
Role of aldosterone in the remnant kidney model in the rat
-
Greene, E.L., Kren, S., Hostetter, T.H., Role of aldosterone in the remnant kidney model in the rat. J Clin Invest 98 (1996), 1063–1068.
-
(1996)
J Clin Invest
, vol.98
, pp. 1063-1068
-
-
Greene, E.L.1
Kren, S.2
Hostetter, T.H.3
-
55
-
-
31544448314
-
Regression of existing glomerulosclerosis by inhibition of aldosterone
-
Aldigier, J.C., Kanjanbuch, T., Ma, L.J., et al. Regression of existing glomerulosclerosis by inhibition of aldosterone. J Am Soc Nephrol 16 (2005), 3306–3314.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 3306-3314
-
-
Aldigier, J.C.1
Kanjanbuch, T.2
Ma, L.J.3
-
56
-
-
85048965970
-
A novel aldosterone antagonist limits renal injury in 5/6 nephrectomy
-
Fujihara, C.K., Kowala, M.C., Breyer, M.D., et al. A novel aldosterone antagonist limits renal injury in 5/6 nephrectomy. Sci Rep, 7, 2017, 7899.
-
(2017)
Sci Rep
, vol.7
, pp. 7899
-
-
Fujihara, C.K.1
Kowala, M.C.2
Breyer, M.D.3
-
57
-
-
33744981628
-
Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker
-
Nagase, M., Shibata, S., Yoshida, S., et al. Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker. Hypertension 47 (2006), 1084–1093.
-
(2006)
Hypertension
, vol.47
, pp. 1084-1093
-
-
Nagase, M.1
Shibata, S.2
Yoshida, S.3
-
58
-
-
84948951465
-
CS-3150, a novel non-steroidal mineralocorticoid receptor antagonist, prevents hypertension and cardiorenal injury in Dahl salt-sensitive hypertensive rats
-
Arai, K., Tsuruoka, H., Homma, T., CS-3150, a novel non-steroidal mineralocorticoid receptor antagonist, prevents hypertension and cardiorenal injury in Dahl salt-sensitive hypertensive rats. Eur J Pharmacol 769 (2015), 266–273.
-
(2015)
Eur J Pharmacol
, vol.769
, pp. 266-273
-
-
Arai, K.1
Tsuruoka, H.2
Homma, T.3
-
59
-
-
57349168398
-
Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease
-
Shibata, S., Nagase, M., Yoshida, S., et al. Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease. Nat Med 14 (2008), 1370–1376.
-
(2008)
Nat Med
, vol.14
, pp. 1370-1376
-
-
Shibata, S.1
Nagase, M.2
Yoshida, S.3
-
60
-
-
20144369870
-
Spironolactone in combination with cilazapril ameliorates proteinuria and renal interstitial fibrosis in rats with anti-Thy-1 irreversible nephritis
-
Asai, M., Monkawa, T., Marumo, T., et al. Spironolactone in combination with cilazapril ameliorates proteinuria and renal interstitial fibrosis in rats with anti-Thy-1 irreversible nephritis. Hypertens Res 27 (2004), 971–978.
-
(2004)
Hypertens Res
, vol.27
, pp. 971-978
-
-
Asai, M.1
Monkawa, T.2
Marumo, T.3
-
61
-
-
33747804321
-
Aldosterone blockage in proliferative glomerulonephritis prevents not only fibrosis, but proliferation as well
-
Gullulu, M., Akdag, I., Kahvecioglu, S., et al. Aldosterone blockage in proliferative glomerulonephritis prevents not only fibrosis, but proliferation as well. Ren Fail 28 (2006), 509–514.
-
(2006)
Ren Fail
, vol.28
, pp. 509-514
-
-
Gullulu, M.1
Akdag, I.2
Kahvecioglu, S.3
-
62
-
-
84877098081
-
Aldosterone mediates glomerular inflammation in experimental mesangial proliferative glomerulonephritis
-
Qin, D., Morita, H., Inui, K., et al. Aldosterone mediates glomerular inflammation in experimental mesangial proliferative glomerulonephritis. J Nephrol 26 (2013), 199–206.
-
(2013)
J Nephrol
, vol.26
, pp. 199-206
-
-
Qin, D.1
Morita, H.2
Inui, K.3
-
63
-
-
80055060496
-
The selective mineralocorticoid receptor antagonist eplerenone is protective in mild anti-GBM glomeru-lonephritis
-
Zitt, E., Eller, K., Huber, J.M., et al. The selective mineralocorticoid receptor antagonist eplerenone is protective in mild anti-GBM glomeru-lonephritis. Int J Clin Exp Pathol 4 (2011), 606–615.
-
(2011)
Int J Clin Exp Pathol
, vol.4
, pp. 606-615
-
-
Zitt, E.1
Eller, K.2
Huber, J.M.3
-
64
-
-
84956927810
-
Suppression of rapidly progressive mouse glomerulonephritis with the non-steroidal mineralocorticoid receptor antagonist BR-4628
-
Ma, F.Y., Han, Y., Nikolic-Paterson, D.J., et al. Suppression of rapidly progressive mouse glomerulonephritis with the non-steroidal mineralocorticoid receptor antagonist BR-4628. PLoS One, 10, 2015, e0145666.
-
(2015)
PLoS One
, vol.10
, pp. e0145666
-
-
Ma, F.Y.1
Han, Y.2
Nikolic-Paterson, D.J.3
-
65
-
-
0032921738
-
Role of aldosterone in renal vascular injury in stroke-prone hypertensive rats
-
Rocha, R., Chander, P.N., Zuckerman, A., Stier, C.T. Jr., Role of aldosterone in renal vascular injury in stroke-prone hypertensive rats. Hypertension 33 (1999), 232–237.
-
(1999)
Hypertension
, vol.33
, pp. 232-237
-
-
Rocha, R.1
Chander, P.N.2
Zuckerman, A.3
Stier, C.T.4
-
66
-
-
0033849916
-
Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo
-
Brown, N.J., Nakamura, S., Ma, L., et al. Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo. Kidney Int 58 (2000), 1219–1227.
-
(2000)
Kidney Int
, vol.58
, pp. 1219-1227
-
-
Brown, N.J.1
Nakamura, S.2
Ma, L.3
-
67
-
-
1842474802
-
Aldosterone antagonism ameliorates proteinuria and nephrosclerosis independent of glomerular dynamics in L-NAME/SHR model
-
Zhou, X., Ono, H., Ono, Y., Frohlich, E.D., Aldosterone antagonism ameliorates proteinuria and nephrosclerosis independent of glomerular dynamics in L-NAME/SHR model. Am J Nephrol 24 (2004), 242–249.
-
(2004)
Am J Nephrol
, vol.24
, pp. 242-249
-
-
Zhou, X.1
Ono, H.2
Ono, Y.3
Frohlich, E.D.4
-
68
-
-
58149145611
-
Spironolactone suppresses inflammation and prevents L-NAME-induced renal injury in rats
-
Ikeda, H., Tsuruya, K., Toyonaga, J., et al. Spironolactone suppresses inflammation and prevents L-NAME-induced renal injury in rats. Kidney Int 75 (2009), 147–155.
-
(2009)
Kidney Int
, vol.75
, pp. 147-155
-
-
Ikeda, H.1
Tsuruya, K.2
Toyonaga, J.3
-
69
-
-
0242366540
-
Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats
-
Blasi, E.R., Rocha, R., Rudolph, A.E., et al. Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats. Kidney Int 63 (2003), 1791–1800.
-
(2003)
Kidney Int
, vol.63
, pp. 1791-1800
-
-
Blasi, E.R.1
Rocha, R.2
Rudolph, A.E.3
-
70
-
-
84856505776
-
Antihypertensive and cardiorenal protective effects of SM-368229, a novel mineralocorticoid receptor antagonist, in aldosterone/salt-treated rats
-
Nariai, T., Fujita, K., Mori, M., et al. Antihypertensive and cardiorenal protective effects of SM-368229, a novel mineralocorticoid receptor antagonist, in aldosterone/salt-treated rats. Pharmacology 89 (2012), 44–52.
-
(2012)
Pharmacology
, vol.89
, pp. 44-52
-
-
Nariai, T.1
Fujita, K.2
Mori, M.3
-
71
-
-
85042491659
-
Preclinical pharmacology of AZD9977: a novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion
-
Bamberg, K., Johansson, U., Edman, K., et al. Preclinical pharmacology of AZD9977: a novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion. PLoS One, 13, 2018, e0193380.
-
(2018)
PLoS One
, vol.13
, pp. e0193380
-
-
Bamberg, K.1
Johansson, U.2
Edman, K.3
-
72
-
-
84983742558
-
CS-3150, a novel nonsteroidal mineralocorticoid receptor antagonist, shows preventive and therapeutic effects on renal injury in deoxycorticosterone acetate/salt-induced hypertensive rats
-
Arai, K., Morikawa, Y., Ubukata, N., et al. CS-3150, a novel nonsteroidal mineralocorticoid receptor antagonist, shows preventive and therapeutic effects on renal injury in deoxycorticosterone acetate/salt-induced hypertensive rats. J Pharmacol Exp Ther 358 (2016), 548–557.
-
(2016)
J Pharmacol Exp Ther
, vol.358
, pp. 548-557
-
-
Arai, K.1
Morikawa, Y.2
Ubukata, N.3
-
73
-
-
84951569040
-
Deoxycorticosterone acetate/salt-induced cardiac but not renal injury is mediated by endothelial mineralocorticoid receptors independently from blood pressure
-
Lother, A., Furst, D., Bergemann, S., et al. Deoxycorticosterone acetate/salt-induced cardiac but not renal injury is mediated by endothelial mineralocorticoid receptors independently from blood pressure. Hypertension 67 (2016), 130–138.
-
(2016)
Hypertension
, vol.67
, pp. 130-138
-
-
Lother, A.1
Furst, D.2
Bergemann, S.3
-
74
-
-
4544374648
-
Prevention of renal fibrosis by spironolactone in mice with complete unilateral ureteral obstruction
-
Trachtman, H., Weiser, A.C., Valderrama, E., et al. Prevention of renal fibrosis by spironolactone in mice with complete unilateral ureteral obstruction. J Urol 172 (2004), 1590–1594.
-
(2004)
J Urol
, vol.172
, pp. 1590-1594
-
-
Trachtman, H.1
Weiser, A.C.2
Valderrama, E.3
-
75
-
-
84891130376
-
Eplerenone-mediated aldosterone blockade prevents renal fibrosis by reducing renal inflammation, interstitial cell proliferation and oxidative stress
-
Chen, H., Sun, F., Zhong, X., et al. Eplerenone-mediated aldosterone blockade prevents renal fibrosis by reducing renal inflammation, interstitial cell proliferation and oxidative stress. Kidney Blood Press Res 37 (2013), 557–566.
-
(2013)
Kidney Blood Press Res
, vol.37
, pp. 557-566
-
-
Chen, H.1
Sun, F.2
Zhong, X.3
-
76
-
-
85018466087
-
The inhibitory effect of eplerenone on cell proliferation in the contralateral kidneys of rats with unilateral ureteral obstruction
-
Wang, C.H., Wang, Z., Liang, L.J., et al. The inhibitory effect of eplerenone on cell proliferation in the contralateral kidneys of rats with unilateral ureteral obstruction. Nephronology 136 (2017), 328–338.
-
(2017)
Nephronology
, vol.136
, pp. 328-338
-
-
Wang, C.H.1
Wang, Z.2
Liang, L.J.3
-
77
-
-
85059686958
-
Diabetic nephropathy: newer therapeutic perspectives
-
Keri, K.C., Samji, N.S., Blumenthal, S., Diabetic nephropathy: newer therapeutic perspectives. J Community Hosp Intern Med Perspect 8 (2018), 200–207.
-
(2018)
J Community Hosp Intern Med Perspect
, vol.8
, pp. 200-207
-
-
Keri, K.C.1
Samji, N.S.2
Blumenthal, S.3
-
78
-
-
4644245230
-
Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats
-
Fujisawa, G., Okada, K., Muto, S., et al. Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats. Kidney Int 66 (2004), 1493–1502.
-
(2004)
Kidney Int
, vol.66
, pp. 1493-1502
-
-
Fujisawa, G.1
Okada, K.2
Muto, S.3
-
79
-
-
33751236177
-
Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus
-
Guo, C., Martinez-Vasquez, D., Mendez, G.P., et al. Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Endocrinology 147 (2006), 5363–5373.
-
(2006)
Endocrinology
, vol.147
, pp. 5363-5373
-
-
Guo, C.1
Martinez-Vasquez, D.2
Mendez, G.P.3
-
80
-
-
36349013809
-
Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats
-
Yuan, J., Jia, R., Bao, Y., Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats. J Renin Angiotensin Aldosterone Syst 8 (2007), 118–126.
-
(2007)
J Renin Angiotensin Aldosterone Syst
, vol.8
, pp. 118-126
-
-
Yuan, J.1
Jia, R.2
Bao, Y.3
-
81
-
-
84862986085
-
Aldosterone antagonists in monotherapy are protective against streptozotocin-induced diabetic nephropathy in rats
-
Banki, N.F., Ver, A., Wagner, L.J., et al. Aldosterone antagonists in monotherapy are protective against streptozotocin-induced diabetic nephropathy in rats. PLoS One, 7, 2012, e39938.
-
(2012)
PLoS One
, vol.7
, pp. e39938
-
-
Banki, N.F.1
Ver, A.2
Wagner, L.J.3
-
82
-
-
84860531024
-
Long-term mineralocorticoid receptor blockade ameliorates progression of experimental diabetic renal disease
-
Lian, M., Hewitson, T.D., Wigg, B., et al. Long-term mineralocorticoid receptor blockade ameliorates progression of experimental diabetic renal disease. Nephrol Dial Transplant 27 (2012), 906–912.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 906-912
-
-
Lian, M.1
Hewitson, T.D.2
Wigg, B.3
-
83
-
-
84859962403
-
Spironolactone improves nephropathy by enhancing glucose-6-phosphate dehydrogenase activity and reducing oxidative stress in diabetic hypertensive rat
-
Pessoa, B.S., Peixoto, E.B., Papadimitriou, A., et al. Spironolactone improves nephropathy by enhancing glucose-6-phosphate dehydrogenase activity and reducing oxidative stress in diabetic hypertensive rat. J Renin Angiotensin Aldosterone Syst 13 (2012), 56–66.
-
(2012)
J Renin Angiotensin Aldosterone Syst
, vol.13
, pp. 56-66
-
-
Pessoa, B.S.1
Peixoto, E.B.2
Papadimitriou, A.3
-
84
-
-
84964461864
-
An additive effect of eplerenone to ACE inhibitor on slowing the progression of diabetic nephropathy in the db/db mice
-
Zhou, G., Johansson, U., Peng, X.R., et al. An additive effect of eplerenone to ACE inhibitor on slowing the progression of diabetic nephropathy in the db/db mice. Am J Transl Res 8 (2016), 1339–1354.
-
(2016)
Am J Transl Res
, vol.8
, pp. 1339-1354
-
-
Zhou, G.1
Johansson, U.2
Peng, X.R.3
-
85
-
-
33646366660
-
Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats
-
Han, S.Y., Kim, C.H., Kim, H.S., et al. Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. J Am Soc Nephrol 17 (2006), 1362–1372.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1362-1372
-
-
Han, S.Y.1
Kim, C.H.2
Kim, H.S.3
-
86
-
-
58049209809
-
Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats
-
Kang, Y.S., Ko, G.J., Lee, M.H., et al. Effect of eplerenone, enalapril and their combination treatment on diabetic nephropathy in type II diabetic rats. Nephrol Dial Transplant 24 (2009), 73–84.
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 73-84
-
-
Kang, Y.S.1
Ko, G.J.2
Lee, M.H.3
-
87
-
-
77249109990
-
Mineralocorticoid receptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats
-
Nishiyama, A., Kobori, H., Konishi, Y., et al. Mineralocorticoid receptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats. J Pharmacol Exp Ther 332 (2010), 1072–1080.
-
(2010)
J Pharmacol Exp Ther
, vol.332
, pp. 1072-1080
-
-
Nishiyama, A.1
Kobori, H.2
Konishi, Y.3
-
88
-
-
85053080463
-
Short- and long-term administration of the non-steroidal mineralocorticoid receptor antagonist finerenone opposes metabolic syndrome-related cardio-renal dysfunction
-
Lachaux, M., Barrera-Chimal, J., Nicol, L., et al. Short- and long-term administration of the non-steroidal mineralocorticoid receptor antagonist finerenone opposes metabolic syndrome-related cardio-renal dysfunction. Diabetes Obes Metab 20 (2018), 2399–2407.
-
(2018)
Diabetes Obes Metab
, vol.20
, pp. 2399-2407
-
-
Lachaux, M.1
Barrera-Chimal, J.2
Nicol, L.3
-
89
-
-
35848952953
-
Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress
-
Nagase, M., Matsui, H., Shibata, S., et al. Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress. Hypertension 50 (2007), 877–883.
-
(2007)
Hypertension
, vol.50
, pp. 877-883
-
-
Nagase, M.1
Matsui, H.2
Shibata, S.3
-
90
-
-
84864698384
-
Role of mineralocorticoid receptor/Rho/Rho-kinase pathway in obesity-related renal injury
-
Tokuyama, H., Wakino, S., Hara, Y., et al. Role of mineralocorticoid receptor/Rho/Rho-kinase pathway in obesity-related renal injury. Int J Obes (Lond) 36 (2012), 1062–1071.
-
(2012)
Int J Obes (Lond)
, vol.36
, pp. 1062-1071
-
-
Tokuyama, H.1
Wakino, S.2
Hara, Y.3
-
91
-
-
84895577445
-
Local mineralocorticoid receptor activation and the role of Rac1 in obesity-related diabetic kidney disease
-
Yoshida, S., Ishizawa, K., Ayuzawa, N., et al. Local mineralocorticoid receptor activation and the role of Rac1 in obesity-related diabetic kidney disease. Nephron Exp Nephrol 126 (2014), 16–24.
-
(2014)
Nephron Exp Nephrol
, vol.126
, pp. 16-24
-
-
Yoshida, S.1
Ishizawa, K.2
Ayuzawa, N.3
-
92
-
-
34548029979
-
New insights into the pathophysiology of cyclosporine nephrotoxicity: a role of aldosterone
-
Bobadilla, N.A., Gamba, G., New insights into the pathophysiology of cyclosporine nephrotoxicity: a role of aldosterone. Am J Physiol Renal Physiol 293 (2007), F2–F9.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. F2-F9
-
-
Bobadilla, N.A.1
Gamba, G.2
-
93
-
-
0023154140
-
The influence of enalapril or spironolactone on experimental cyclosporin nephrotoxicity
-
McAuley, F.T., Whiting, P.H., Thomson, A.W., Simpson, J.G., The influence of enalapril or spironolactone on experimental cyclosporin nephrotoxicity. Biochem Pharmacol 36 (1987), 699–703.
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 699-703
-
-
McAuley, F.T.1
Whiting, P.H.2
Thomson, A.W.3
Simpson, J.G.4
-
94
-
-
26844546641
-
Renocortical mRNA expression of vasoactive factors during spironolactone protective effect in chronic cyclosporine nephrotoxicity
-
Pérez-Rojas, J.M., Derive, S., Blanco, J.A., et al. Renocortical mRNA expression of vasoactive factors during spironolactone protective effect in chronic cyclosporine nephrotoxicity. Am J Physiol Renal Physiol 289 (2005), F1020–F1030.
-
(2005)
Am J Physiol Renal Physiol
, vol.289
, pp. F1020-F1030
-
-
Pérez-Rojas, J.M.1
Derive, S.2
Blanco, J.A.3
-
95
-
-
58549092050
-
Inhibition of mineralocorticoid receptors with eplerenone alleviates short-term cyclosporin A nephrotoxicity in conscious rats
-
Nielsen, F.T., Jensen, B.L., Marcussen, N., et al. Inhibition of mineralocorticoid receptors with eplerenone alleviates short-term cyclosporin A nephrotoxicity in conscious rats. Nephrol Dial Transplant 23 (2008), 2777–2783.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 2777-2783
-
-
Nielsen, F.T.1
Jensen, B.L.2
Marcussen, N.3
-
96
-
-
84942683836
-
Deletion of mineralocorticoid receptors in smooth muscle cells blunts renal vascular resistance following acute cyclosporine administration
-
Amador, C.A., Bertocchio, J.P., Andre-Gregoire, G., et al. Deletion of mineralocorticoid receptors in smooth muscle cells blunts renal vascular resistance following acute cyclosporine administration. Kidney Int 89 (2016), 354–362.
-
(2016)
Kidney Int
, vol.89
, pp. 354-362
-
-
Amador, C.A.1
Bertocchio, J.P.2
Andre-Gregoire, G.3
-
97
-
-
6444245944
-
Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity
-
Feria, I., Pichardo, I., Juarez, P., et al. Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity. Kidney Int 63 (2003), 43–52.
-
(2003)
Kidney Int
, vol.63
, pp. 43-52
-
-
Feria, I.1
Pichardo, I.2
Juarez, P.3
-
98
-
-
84873966799
-
The mineralocorticoid receptor antagonist eplerenone reduces renal interstitial fibrosis after long-term cyclosporine treatment in rat: antagonizing cyclosporine nephrotoxicity
-
Nielsen, F.T., Jensen, B.L., Hansen, P.B., et al. The mineralocorticoid receptor antagonist eplerenone reduces renal interstitial fibrosis after long-term cyclosporine treatment in rat: antagonizing cyclosporine nephrotoxicity. BMC Nephrol, 14, 2013, 42.
-
(2013)
BMC Nephrol
, vol.14
, pp. 42
-
-
Nielsen, F.T.1
Jensen, B.L.2
Hansen, P.B.3
-
99
-
-
33846210660
-
Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity
-
Pérez-Rojas, J., Blanco, J.A., Cruz, C., et al. Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity. Am J Physiol Renal Physiol 292 (2007), F131–F139.
-
(2007)
Am J Physiol Renal Physiol
, vol.292
, pp. F131-F139
-
-
Pérez-Rojas, J.1
Blanco, J.A.2
Cruz, C.3
-
100
-
-
66049119620
-
Spironolactone ameliorates transplant vasculopathy in renal chronic transplant dysfunction in rats
-
Waanders, F., Rienstra, H., Boer, M.W., et al. Spironolactone ameliorates transplant vasculopathy in renal chronic transplant dysfunction in rats. Am J Physiol Renal Physiol 296 (2009), F1072–F1079.
-
(2009)
Am J Physiol Renal Physiol
, vol.296
, pp. F1072-F1079
-
-
Waanders, F.1
Rienstra, H.2
Boer, M.W.3
-
101
-
-
84864826579
-
Mineralocorticoid receptor antagonism and aldosterone synthesis inhibition do not improve glomerulosclerosis and renal interstitial fibrosis in a model of chronic kidney allograft injury
-
Lahmer, T., Hermans, R., Schmaderer, C., et al. Mineralocorticoid receptor antagonism and aldosterone synthesis inhibition do not improve glomerulosclerosis and renal interstitial fibrosis in a model of chronic kidney allograft injury. Kidney Blood Press Res 35 (2012), 561–567.
-
(2012)
Kidney Blood Press Res
, vol.35
, pp. 561-567
-
-
Lahmer, T.1
Hermans, R.2
Schmaderer, C.3
-
102
-
-
49849099862
-
Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and prevents oxidative stress in uremic rats
-
Michea, L., Villagran, A., Urzua, A., et al. Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and prevents oxidative stress in uremic rats. Hypertension 52 (2008), 295–300.
-
(2008)
Hypertension
, vol.52
, pp. 295-300
-
-
Michea, L.1
Villagran, A.2
Urzua, A.3
-
103
-
-
85049758919
-
Mineralocorticoid receptor antagonism improves diastolic dysfunction in chronic kidney disease in mice
-
Bonnard, B., Pieronne-Deperrois, M., Djerada, Z., et al. Mineralocorticoid receptor antagonism improves diastolic dysfunction in chronic kidney disease in mice. J Mol Cell Cardiol 121 (2018), 124–133.
-
(2018)
J Mol Cell Cardiol
, vol.121
, pp. 124-133
-
-
Bonnard, B.1
Pieronne-Deperrois, M.2
Djerada, Z.3
-
104
-
-
84929688304
-
Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice
-
Bostick, B., Habibi, J., DeMarco, V.G., et al. Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice. Am J Physiol Heart Circ Physiol 308 (2015), H1126–H1135.
-
(2015)
Am J Physiol Heart Circ Physiol
, vol.308
, pp. H1126-H1135
-
-
Bostick, B.1
Habibi, J.2
DeMarco, V.G.3
-
105
-
-
84958818424
-
Endothelial mineralocorticoid receptor mediates diet-induced aortic stiffness in females
-
Jia, G., Habibi, J., Aroor, A.R., et al. Endothelial mineralocorticoid receptor mediates diet-induced aortic stiffness in females. Circ Res 118 (2016), 935–943.
-
(2016)
Circ Res
, vol.118
, pp. 935-943
-
-
Jia, G.1
Habibi, J.2
Aroor, A.R.3
-
106
-
-
84855359133
-
Protective effects of mineralocorticoid receptor blockade against neuropathy in experimental diabetic rats
-
Takata, H., Takeda, Y., Zhu, A., et al. Protective effects of mineralocorticoid receptor blockade against neuropathy in experimental diabetic rats. Diabetes Obes Metab 14 (2012), 155–162.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 155-162
-
-
Takata, H.1
Takeda, Y.2
Zhu, A.3
-
107
-
-
79954571357
-
Mineralocorticoid receptor-mediated DNA damage in kidneys of DOCA-salt hypertensive rats
-
Schupp, N., Kolkhof, P., Queisser, N., et al. Mineralocorticoid receptor-mediated DNA damage in kidneys of DOCA-salt hypertensive rats. FASEB J 25 (2011), 968–978.
-
(2011)
FASEB J
, vol.25
, pp. 968-978
-
-
Schupp, N.1
Kolkhof, P.2
Queisser, N.3
-
108
-
-
12144286297
-
Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats
-
Nishiyama, A., Yao, L., Nagai, Y., et al. Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats. Hypertension 43 (2004), 841–848.
-
(2004)
Hypertension
, vol.43
, pp. 841-848
-
-
Nishiyama, A.1
Yao, L.2
Nagai, Y.3
-
109
-
-
2442490850
-
Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone
-
Keidar, S., Kaplan, M., Pavlotzky, E., et al. Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone. Circulation 109 (2004), 2213–2220.
-
(2004)
Circulation
, vol.109
, pp. 2213-2220
-
-
Keidar, S.1
Kaplan, M.2
Pavlotzky, E.3
-
110
-
-
40849083771
-
Aldosterone induces superoxide generation via Rac1 activation in endothelial cells
-
Iwashima, F., Yoshimoto, T., Minami, I., et al. Aldosterone induces superoxide generation via Rac1 activation in endothelial cells. Endocrinology 149 (2008), 1009–1014.
-
(2008)
Endocrinology
, vol.149
, pp. 1009-1014
-
-
Iwashima, F.1
Yoshimoto, T.2
Minami, I.3
-
111
-
-
21244497660
-
The mineralocorticoid receptor and oxidative stress
-
Fiebeler, A., Luft, F.C., The mineralocorticoid receptor and oxidative stress. Heart Fail Rev 10 (2005), 47–52.
-
(2005)
Heart Fail Rev
, vol.10
, pp. 47-52
-
-
Fiebeler, A.1
Luft, F.C.2
-
112
-
-
35548992302
-
Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence
-
Min, L.J., Mogi, M., Iwanami, J., et al. Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence. Cardiovasc Res 76 (2007), 506–516.
-
(2007)
Cardiovasc Res
, vol.76
, pp. 506-516
-
-
Min, L.J.1
Mogi, M.2
Iwanami, J.3
-
113
-
-
84868662652
-
Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors
-
McCurley, A., Pires, P.W., Bender, S.B., et al. Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors. Nat Med 18 (2012), 1429–1433.
-
(2012)
Nat Med
, vol.18
, pp. 1429-1433
-
-
McCurley, A.1
Pires, P.W.2
Bender, S.B.3
-
114
-
-
84925780395
-
Oxidative stress in patients affected by primary aldosteronism
-
; discussion 2029
-
Petramala, L., Pignatelli, P., Carnevale, R., et al. Oxidative stress in patients affected by primary aldosteronism. J Hypertens 32 (2014), 2022–2029; discussion 2029.
-
(2014)
J Hypertens
, vol.32
, pp. 2022-2029
-
-
Petramala, L.1
Pignatelli, P.2
Carnevale, R.3
-
115
-
-
84876798791
-
Mineralocorticoid receptor blockade reduced oxidative stress in renal transplant recipients: a double-blind, randomized pilot study
-
Ojeda-Cervantes, M., Barrera-Chimal, J., Alberu, J., et al. Mineralocorticoid receptor blockade reduced oxidative stress in renal transplant recipients: a double-blind, randomized pilot study. Am J Nephrol 37 (2013), 481–490.
-
(2013)
Am J Nephrol
, vol.37
, pp. 481-490
-
-
Ojeda-Cervantes, M.1
Barrera-Chimal, J.2
Alberu, J.3
-
116
-
-
33744954417
-
Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy
-
Takebayashi, K., Matsumoto, S., Aso, Y., Inukai, T., Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy. J Clin Endocrinol Metab 91 (2006), 2214–2217.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2214-2217
-
-
Takebayashi, K.1
Matsumoto, S.2
Aso, Y.3
Inukai, T.4
-
117
-
-
33746343979
-
Anti-inflammatory effect of spironolactone on human peripheral blood mononuclear cells
-
Miura, R., Nakamura, K., Miura, D., et al. Anti-inflammatory effect of spironolactone on human peripheral blood mononuclear cells. J Pharmacol Sci 101 (2006), 256–259.
-
(2006)
J Pharmacol Sci
, vol.101
, pp. 256-259
-
-
Miura, R.1
Nakamura, K.2
Miura, D.3
-
118
-
-
85032859467
-
Deletion of the mineralocorticoid receptor in myeloid cells attenuates central nervous system autoimmunity
-
Montes-Cobos, E., Schweingruber, N., Li, X., et al. Deletion of the mineralocorticoid receptor in myeloid cells attenuates central nervous system autoimmunity. Front Immunol, 8, 2017, 1319.
-
(2017)
Front Immunol
, vol.8
, pp. 1319
-
-
Montes-Cobos, E.1
Schweingruber, N.2
Li, X.3
-
119
-
-
84960351341
-
Mineralocorticoid receptor deficiency in macrophages inhibits neointimal hyperplasia and suppresses macrophage inflammation through SGK1-AP1/NF-kappaB pathways
-
Sun, J.Y., Li, C., Shen, Z.X., et al. Mineralocorticoid receptor deficiency in macrophages inhibits neointimal hyperplasia and suppresses macrophage inflammation through SGK1-AP1/NF-kappaB pathways. Arterioscler Thromb Vasc Biol 36 (2016), 874–885.
-
(2016)
Arterioscler Thromb Vasc Biol
, vol.36
, pp. 874-885
-
-
Sun, J.Y.1
Li, C.2
Shen, Z.X.3
-
120
-
-
84897086339
-
Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes
-
Amador, C.A., Barrientos, V., Pena, J., et al. Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes. Hypertension 63 (2014), 797–803.
-
(2014)
Hypertension
, vol.63
, pp. 797-803
-
-
Amador, C.A.1
Barrientos, V.2
Pena, J.3
-
121
-
-
73949146218
-
Aldosterone promotes autoimmune damage by enhancing Th17-mediated immunity
-
Herrada, A.A., Contreras, F.J., Marini, N.P., et al. Aldosterone promotes autoimmune damage by enhancing Th17-mediated immunity. J Immunol 184 (2010), 191–202.
-
(2010)
J Immunol
, vol.184
, pp. 191-202
-
-
Herrada, A.A.1
Contreras, F.J.2
Marini, N.P.3
-
122
-
-
0034119204
-
Local angiotensin II and transforming growth factor-beta1 in renal fibrosis of rats
-
Sun, Y., Zhang, J., Zhang, J.Q., Ramires, F.J., Local angiotensin II and transforming growth factor-beta1 in renal fibrosis of rats. Hypertension 35 (2000), 1078–1084.
-
(2000)
Hypertension
, vol.35
, pp. 1078-1084
-
-
Sun, Y.1
Zhang, J.2
Zhang, J.Q.3
Ramires, F.J.4
-
123
-
-
84954057718
-
Aldosterone induces renal fibrosis and inflammatory M1-macrophage subtype via mineralocorticoid receptor in rats
-
Martin-Fernandez, B., Rubio-Navarro, A., Cortegano, I., et al. Aldosterone induces renal fibrosis and inflammatory M1-macrophage subtype via mineralocorticoid receptor in rats. PLoS One, 11, 2016, e0145946.
-
(2016)
PLoS One
, vol.11
, pp. e0145946
-
-
Martin-Fernandez, B.1
Rubio-Navarro, A.2
Cortegano, I.3
-
124
-
-
84884814686
-
Aldosterone stimulates fibronectin synthesis in renal fibroblasts through mineralocorticoid receptor-dependent and independent mechanisms
-
Chen, D., Chen, Z., Park, C., et al. Aldosterone stimulates fibronectin synthesis in renal fibroblasts through mineralocorticoid receptor-dependent and independent mechanisms. Gene 531 (2013), 23–30.
-
(2013)
Gene
, vol.531
, pp. 23-30
-
-
Chen, D.1
Chen, Z.2
Park, C.3
-
125
-
-
32944475760
-
Plasma osteopontin levels are higher in patients with primary aldosteronism than in patients with essential hypertension
-
Irita, J., Okura, T., Manabe, S., et al. Plasma osteopontin levels are higher in patients with primary aldosteronism than in patients with essential hypertension. Am J Hypertens 19 (2006), 293–297.
-
(2006)
Am J Hypertens
, vol.19
, pp. 293-297
-
-
Irita, J.1
Okura, T.2
Manabe, S.3
-
126
-
-
84869861374
-
Aldosterone induces kidney fibroblast proliferation via activation of growth factor receptors and PI3K/MAPK signalling
-
Huang, L.L., Nikolic-Paterson, D.J., Ma, F.Y., Tesch, G.H., Aldosterone induces kidney fibroblast proliferation via activation of growth factor receptors and PI3K/MAPK signalling. Nephron Exp Nephrol 120 (2012), e115–e122.
-
(2012)
Nephron Exp Nephrol
, vol.120
, pp. e115-e122
-
-
Huang, L.L.1
Nikolic-Paterson, D.J.2
Ma, F.Y.3
Tesch, G.H.4
-
127
-
-
84894456986
-
Smooth muscle cell mineralocorticoid receptors are mandatory for aldosterone-salt to induce vascular stiffness
-
Galmiche, G., Pizard, A., Gueret, A., et al. Smooth muscle cell mineralocorticoid receptors are mandatory for aldosterone-salt to induce vascular stiffness. Hypertension 63 (2014), 520–526.
-
(2014)
Hypertension
, vol.63
, pp. 520-526
-
-
Galmiche, G.1
Pizard, A.2
Gueret, A.3
-
128
-
-
84871813952
-
Galectin-3 mediates aldosterone-induced vascular fibrosis
-
Calvier, L., Miana, M., Reboul, P., et al. Galectin-3 mediates aldosterone-induced vascular fibrosis. Arterioscler Thromb Vasc Biol 33 (2013), 67–75.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 67-75
-
-
Calvier, L.1
Miana, M.2
Reboul, P.3
-
129
-
-
84894939299
-
Aldosterone promotes vascular remodeling by direct effects on smooth muscle cell mineralocorticoid receptors
-
Pruthi, D., McCurley, A., Aronovitz, M., et al. Aldosterone promotes vascular remodeling by direct effects on smooth muscle cell mineralocorticoid receptors. Arterioscler Thromb Vasc Biol 34 (2014), 355–364.
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, pp. 355-364
-
-
Pruthi, D.1
McCurley, A.2
Aronovitz, M.3
-
130
-
-
84940025127
-
Neutrophil gelatinase-associated lipocalin, a novel mineralocorticoid biotarget, mediates vascular profibrotic effects of mineralocorticoids
-
Tarjus, A., Martinez-Martinez, E., Amador, C., et al. Neutrophil gelatinase-associated lipocalin, a novel mineralocorticoid biotarget, mediates vascular profibrotic effects of mineralocorticoids. Hypertension 66 (2015), 158–166.
-
(2015)
Hypertension
, vol.66
, pp. 158-166
-
-
Tarjus, A.1
Martinez-Martinez, E.2
Amador, C.3
-
131
-
-
85037677763
-
Aldosterone target NGAL (neutrophil gelatinase-associated lipocalin) is involved in cardiac remodeling after myocardial infarction through NFkappaB pathway
-
Martinez-Martinez, E., Buonafine, M., Boukhalfa, I., et al. Aldosterone target NGAL (neutrophil gelatinase-associated lipocalin) is involved in cardiac remodeling after myocardial infarction through NFkappaB pathway. Hypertension 70 (2017), 1148–1156.
-
(2017)
Hypertension
, vol.70
, pp. 1148-1156
-
-
Martinez-Martinez, E.1
Buonafine, M.2
Boukhalfa, I.3
-
132
-
-
84920268893
-
The impact of galectin-3 inhibition on aldosterone-induced cardiac and renal injuries
-
Calvier, L., Martinez-Martinez, E., Miana, M., et al. The impact of galectin-3 inhibition on aldosterone-induced cardiac and renal injuries. JACC Heart Fail 3 (2015), 59–67.
-
(2015)
JACC Heart Fail
, vol.3
, pp. 59-67
-
-
Calvier, L.1
Martinez-Martinez, E.2
Miana, M.3
-
133
-
-
84928326296
-
Mineralocorticoid and SGK1-sensitive inflammation and tissue fibrosis
-
Artunc, F., Lang, F., Mineralocorticoid and SGK1-sensitive inflammation and tissue fibrosis. Nephron Physiol 128 (2014), 35–39.
-
(2014)
Nephron Physiol
, vol.128
, pp. 35-39
-
-
Artunc, F.1
Lang, F.2
-
134
-
-
0242384919
-
Aldosterone stimulates epidermal growth factor receptor expression
-
Krug, A.W., Grossmann, C., Schuster, C., et al. Aldosterone stimulates epidermal growth factor receptor expression. J Biol Chem 278 (2003), 43060–43066.
-
(2003)
J Biol Chem
, vol.278
, pp. 43060-43066
-
-
Krug, A.W.1
Grossmann, C.2
Schuster, C.3
-
135
-
-
70049108525
-
Aldosterone antagonists for preventing the progression of chronic kidney disease
-
Bolignano, D., Palmer, S.C., Navaneethan, S.D., Strippoli, G.F., Aldosterone antagonists for preventing the progression of chronic kidney disease. Cochrane Database Syst Rev, 2014, CD007004.
-
(2014)
Cochrane Database Syst Rev
, pp. CD007004
-
-
Bolignano, D.1
Palmer, S.C.2
Navaneethan, S.D.3
Strippoli, G.F.4
-
136
-
-
84992176768
-
Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis
-
Currie, G., Taylor, A.H., Fujita, T., et al. Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis. BMC Nephrol, 17, 2016, 127.
-
(2016)
BMC Nephrol
, vol.17
, pp. 127
-
-
Currie, G.1
Taylor, A.H.2
Fujita, T.3
-
137
-
-
84941172298
-
Spironolactone add-on for preventing or slowing the progression of diabetic nephropathy: a meta-analysis
-
Hou, J., Xiong, W., Cao, L., et al. Spironolactone add-on for preventing or slowing the progression of diabetic nephropathy: a meta-analysis. Clin Ther 37 (2015), 2086–2103.e10.
-
(2015)
Clin Ther
, vol.37
, pp. 2086-2103.e10
-
-
Hou, J.1
Xiong, W.2
Cao, L.3
-
138
-
-
84940729269
-
Effect of finerenone on albuminuria in patients with diabetic nephropathy: a randomized clinical trial
-
Bakris, G.L., Agarwal, R., Chan, J.C., et al. Effect of finerenone on albuminuria in patients with diabetic nephropathy: a randomized clinical trial. JAMA 314 (2015), 884–894.
-
(2015)
JAMA
, vol.314
, pp. 884-894
-
-
Bakris, G.L.1
Agarwal, R.2
Chan, J.C.3
-
139
-
-
33845302661
-
Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease
-
Bianchi, S., Bigazzi, R., Campese, V.M., Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease. Kidney Int 70 (2006), 2116–2123.
-
(2006)
Kidney Int
, vol.70
, pp. 2116-2123
-
-
Bianchi, S.1
Bigazzi, R.2
Campese, V.M.3
-
140
-
-
80455145142
-
Moderate antiproteinuric effect of add-on aldosterone blockade with eplerenone in non-diabetic chronic kidney disease. A randomized cross-over study
-
Boesby, L., Elung-Jensen, T., Klausen, T.W., et al. Moderate antiproteinuric effect of add-on aldosterone blockade with eplerenone in non-diabetic chronic kidney disease. A randomized cross-over study. PLoS One, 6, 2011, e26904.
-
(2011)
PLoS One
, vol.6
, pp. e26904
-
-
Boesby, L.1
Elung-Jensen, T.2
Klausen, T.W.3
-
141
-
-
84938947090
-
Drug-induced reduction in albuminuria is associated with subsequent renoprotection: a meta-analysis
-
Heerspink, H.J., Kropelin, T.F., Hoekman, J., de Zeeuw, D., Drug-induced reduction in albuminuria is associated with subsequent renoprotection: a meta-analysis. J Am Soc Nephrol 26 (2015), 2055–2064.
-
(2015)
J Am Soc Nephrol
, vol.26
, pp. 2055-2064
-
-
Heerspink, H.J.1
Kropelin, T.F.2
Hoekman, J.3
de Zeeuw, D.4
-
142
-
-
84949870925
-
Proteinuria as a surrogate marker for renal outcome: Are we there yet?
-
Avasare, R.S., Radhakrishnan, J., Proteinuria as a surrogate marker for renal outcome: Are we there yet?. Kidney Int 88 (2015), 1228–1230.
-
(2015)
Kidney Int
, vol.88
, pp. 1228-1230
-
-
Avasare, R.S.1
Radhakrishnan, J.2
-
143
-
-
67650451498
-
Proteinuria as a surrogate outcome in CKD: report of a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration
-
Levey, A.S., Cattran, D., Friedman, A., et al. Proteinuria as a surrogate outcome in CKD: report of a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration. Am J Kidney Dis 54 (2009), 205–226.
-
(2009)
Am J Kidney Dis
, vol.54
, pp. 205-226
-
-
Levey, A.S.1
Cattran, D.2
Friedman, A.3
-
144
-
-
85056892085
-
Table of surrogate endpoints that were the basis of drug approval or licensure
-
Available at: Accessed July 2, 2019
-
US Food and Drug Administration, Table of surrogate endpoints that were the basis of drug approval or licensure. Available at: https://www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/ucm613636.htm Accessed July 2, 2019.
-
-
-
US Food and Drug Administration1
-
145
-
-
85024913280
-
Exploring novel endpoints for clinical trials in kidney disease: challenges and opportunities
-
Roy-Chaudhury, P., Exploring novel endpoints for clinical trials in kidney disease: challenges and opportunities. Kidney Int Rep 2 (2017), 295–296.
-
(2017)
Kidney Int Rep
, vol.2
, pp. 295-296
-
-
Roy-Chaudhury, P.1
-
146
-
-
0942287104
-
The number, quality, and coverage of randomized controlled trials in nephrology
-
Strippoli, G.F., Craig, J.C., Schena, F.P., The number, quality, and coverage of randomized controlled trials in nephrology. J Am Soc Nephrol 15 (2004), 411–419.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 411-419
-
-
Strippoli, G.F.1
Craig, J.C.2
Schena, F.P.3
-
147
-
-
84911459484
-
GFR decline as an end point for clinical trials in CKD: a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration
-
Levey, A.S., Inker, L.A., Matsushita, K., et al. GFR decline as an end point for clinical trials in CKD: a scientific workshop sponsored by the National Kidney Foundation and the US Food and Drug Administration. Am J Kidney Dis 64 (2014), 821–835.
-
(2014)
Am J Kidney Dis
, vol.64
, pp. 821-835
-
-
Levey, A.S.1
Inker, L.A.2
Matsushita, K.3
-
148
-
-
84869417804
-
Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice
-
Zannad, F., Gattis Stough, W., Rossignol, P., et al. Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice. Eur Heart J 33 (2012), 2782–2795.
-
(2012)
Eur Heart J
, vol.33
, pp. 2782-2795
-
-
Zannad, F.1
Gattis Stough, W.2
Rossignol, P.3
-
149
-
-
84980396108
-
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC
-
Ponikowski, P., Voors, A.A., Anker, S.D., et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 37 (2016), 2129–2200.
-
(2016)
Eur Heart J
, vol.37
, pp. 2129-2200
-
-
Ponikowski, P.1
Voors, A.A.2
Anker, S.D.3
-
150
-
-
84999711630
-
A tentative interpretation of the TOPCAT trial based on randomized evidence from the brain natriuretic peptide stratum analysis
-
Girerd, N., Ferreira, J.P., Rossignol, P., Zannad, F., A tentative interpretation of the TOPCAT trial based on randomized evidence from the brain natriuretic peptide stratum analysis. Eur J Heart Fail 18 (2016), 1411–1414.
-
(2016)
Eur J Heart Fail
, vol.18
, pp. 1411-1414
-
-
Girerd, N.1
Ferreira, J.P.2
Rossignol, P.3
Zannad, F.4
-
151
-
-
84886023778
-
Safety and efficacy of eplerenone in patients at high risk for hyperkalemia and/or worsening renal function: analyses of the EMPHASIS-HF study subgroups (eplerenone in mild patients hospitalization and survival study in heart failure)
-
Eschalier, R., McMurray, J.J., Swedberg, K., et al. Safety and efficacy of eplerenone in patients at high risk for hyperkalemia and/or worsening renal function: analyses of the EMPHASIS-HF study subgroups (eplerenone in mild patients hospitalization and survival study in heart failure). J Am Coll Cardiol 62 (2013), 1585–1593.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 1585-1593
-
-
Eschalier, R.1
McMurray, J.J.2
Swedberg, K.3
-
152
-
-
85050479404
-
Association between mineralocorticoid receptor antagonist use and outcome in myocardial infarction patients with heart failure
-
pii: e009359
-
Löfman, I., Szummer, K., Olsson, H., et al. Association between mineralocorticoid receptor antagonist use and outcome in myocardial infarction patients with heart failure. J Am Heart Assoc, 7, 2018 pii: e009359.
-
(2018)
J Am Heart Assoc
, vol.7
-
-
Löfman, I.1
Szummer, K.2
Olsson, H.3
-
153
-
-
84882415231
-
Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial
-
Pitt, B., Kober, L., Ponikowski, P., et al. Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial. Eur Heart J 34 (2013), 2453–2463.
-
(2013)
Eur Heart J
, vol.34
, pp. 2453-2463
-
-
Pitt, B.1
Kober, L.2
Ponikowski, P.3
-
154
-
-
67651048925
-
Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: a randomized controlled trial
-
Edwards, N.C., Steeds, R.P., Stewart, P.M., et al. Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: a randomized controlled trial. J Am Coll Cardiol 54 (2009), 505–512.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 505-512
-
-
Edwards, N.C.1
Steeds, R.P.2
Stewart, P.M.3
-
155
-
-
78149424364
-
Effect of spironolactone on left ventricular systolic and diastolic function in patients with early stage chronic kidney disease
-
Edwards, N.C., Ferro, C.J., Kirkwood, H., et al. Effect of spironolactone on left ventricular systolic and diastolic function in patients with early stage chronic kidney disease. Am J Cardiol 106 (2010), 1505–1511.
-
(2010)
Am J Cardiol
, vol.106
, pp. 1505-1511
-
-
Edwards, N.C.1
Ferro, C.J.2
Kirkwood, H.3
-
156
-
-
84877969830
-
Eplerenone attenuates pulse wave reflection in chronic kidney disease stage 3-4—a randomized controlled study
-
Boesby, L., Elung-Jensen, T., Strandgaard, S., Kamper, A.L., Eplerenone attenuates pulse wave reflection in chronic kidney disease stage 3-4—a randomized controlled study. PLoS One, 8, 2013, e64549.
-
(2013)
PLoS One
, vol.8
, pp. e64549
-
-
Boesby, L.1
Elung-Jensen, T.2
Strandgaard, S.3
Kamper, A.L.4
-
157
-
-
85023205146
-
30 years of the mineralocorticoid receptor: the role of the mineralocorticoid receptor in the vasculature
-
DuPont, J.J., Jaffe, I.Z., 30 years of the mineralocorticoid receptor: the role of the mineralocorticoid receptor in the vasculature. J Endocrinol 234 (2017), T67–T82.
-
(2017)
J Endocrinol
, vol.234
, pp. T67-T82
-
-
DuPont, J.J.1
Jaffe, I.Z.2
-
158
-
-
67649770575
-
Spironolactone in chronic hemodialysis patients improves cardiac function
-
Taheri, S., Mortazavi, M., Shahidi, S., et al. Spironolactone in chronic hemodialysis patients improves cardiac function. Saudi J Kidney Dis Transpl 20 (2009), 392–397.
-
(2009)
Saudi J Kidney Dis Transpl
, vol.20
, pp. 392-397
-
-
Taheri, S.1
Mortazavi, M.2
Shahidi, S.3
-
159
-
-
84862697216
-
A prospective double-blind randomized placebo-controlled clinical trial to evaluate the safety and efficacy of spironolactone in patients with advanced congestive heart failure on continuous ambulatory peritoneal dialysis
-
Taheri, S., Mortazavi, M., Pourmoghadas, A., et al. A prospective double-blind randomized placebo-controlled clinical trial to evaluate the safety and efficacy of spironolactone in patients with advanced congestive heart failure on continuous ambulatory peritoneal dialysis. Saudi J Kidney Dis Transpl 23 (2012), 507–512.
-
(2012)
Saudi J Kidney Dis Transpl
, vol.23
, pp. 507-512
-
-
Taheri, S.1
Mortazavi, M.2
Pourmoghadas, A.3
-
160
-
-
48749099983
-
Left ventricular dysfunction in the haemodialysis population
-
Sood, M.M., Pauly, R.P., Rigatto, C., Komenda, P., Left ventricular dysfunction in the haemodialysis population. NDT Plus 1 (2008), 199–205.
-
(2008)
NDT Plus
, vol.1
, pp. 199-205
-
-
Sood, M.M.1
Pauly, R.P.2
Rigatto, C.3
Komenda, P.4
-
161
-
-
85062702483
-
A randomized controlled trial of the effect of spironolactone on left ventricular mass in hemodialysis patients
-
Hammer, F., Malzahn, U., Donhauser, J., et al. A randomized controlled trial of the effect of spironolactone on left ventricular mass in hemodialysis patients. Kidney Int 95 (2019), 938–991.
-
(2019)
Kidney Int
, vol.95
, pp. 938-991
-
-
Hammer, F.1
Malzahn, U.2
Donhauser, J.3
-
162
-
-
85083070639
-
Safety and cardiovascular efficacy of spironolactone in dialysis-dependent ESRD (SPin-D): a randomized, placebo-controlled, multiple dosage trial
-
pii: S0085-2538(18)30641-0
-
Charytan, D.M., Himmelfarb, J., Ikizler, T.A., et al. Safety and cardiovascular efficacy of spironolactone in dialysis-dependent ESRD (SPin-D): a randomized, placebo-controlled, multiple dosage trial. Kidney Int, 2018 pii: S0085-2538(18)30641-0.
-
(2018)
Kidney Int
-
-
Charytan, D.M.1
Himmelfarb, J.2
Ikizler, T.A.3
-
163
-
-
84975704707
-
The safety and efficacy of mineralocorticoid receptor antagonists in patients who require dialysis: a systematic review and meta-analysis
-
Quach, K., Lvtvyn, L., Baigent, C., et al. The safety and efficacy of mineralocorticoid receptor antagonists in patients who require dialysis: a systematic review and meta-analysis. Am J Kidney Dis 68 (2016), 591–598.
-
(2016)
Am J Kidney Dis
, vol.68
, pp. 591-598
-
-
Quach, K.1
Lvtvyn, L.2
Baigent, C.3
-
164
-
-
84900310067
-
Benefits of aldosterone receptor antagonism in chronic kidney disease (BARACK D) trial-a multi-centre, prospective, randomised, open, blinded end-point, 36-month study of 2,616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25 mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: study protocol for a randomized controlled trial
-
Hill, N.R., Lasserson, D., Thompson, B., et al. Benefits of aldosterone receptor antagonism in chronic kidney disease (BARACK D) trial-a multi-centre, prospective, randomised, open, blinded end-point, 36-month study of 2,616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25 mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: study protocol for a randomized controlled trial. Trials, 15, 2014, 160.
-
(2014)
Trials
, vol.15
, pp. 160
-
-
Hill, N.R.1
Lasserson, D.2
Thompson, B.3
-
165
-
-
84900435185
-
Spironolactone to prevent cardiovascular events in early-stage chronic kidney disease (STOP-CKD): study protocol for a randomized controlled pilot trial
-
Ng, K.P., Jain, P., Heer, G., et al. Spironolactone to prevent cardiovascular events in early-stage chronic kidney disease (STOP-CKD): study protocol for a randomized controlled pilot trial. Trials, 15, 2014, 158.
-
(2014)
Trials
, vol.15
, pp. 158
-
-
Ng, K.P.1
Jain, P.2
Heer, G.3
-
166
-
-
84960386411
-
Results and lessons from the Spironolactone To Prevent Cardiovascular Events in Early Stage Chronic Kidney Disease (STOP-CKD) randomised controlled trial
-
Ng, K.P., Jain, P., Gill, P.S., et al. Results and lessons from the Spironolactone To Prevent Cardiovascular Events in Early Stage Chronic Kidney Disease (STOP-CKD) randomised controlled trial. BMJ Open, 6, 2016, e010519.
-
(2016)
BMJ Open
, vol.6
, pp. e010519
-
-
Ng, K.P.1
Jain, P.2
Gill, P.S.3
-
167
-
-
85065349163
-
EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) Study: study protocol for a randomized controlled trial
-
Girerd, S., Frimat, L., Ducloux, D., et al. EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) Study: study protocol for a randomized controlled trial. Trials, 19, 2018, 595.
-
(2018)
Trials
, vol.19
, pp. 595
-
-
Girerd, S.1
Frimat, L.2
Ducloux, D.3
-
168
-
-
85026921596
-
Randomized controlled trial of mineralocorticoid receptor blockade in children with chronic kidney allograft nephropathy
-
Medeiros, M., Velasquez-Jones, L., Hernandez, A.M., et al. Randomized controlled trial of mineralocorticoid receptor blockade in children with chronic kidney allograft nephropathy. Clin J Am Soc Nephrol 12 (2017), 1291–1300.
-
(2017)
Clin J Am Soc Nephrol
, vol.12
, pp. 1291-1300
-
-
Medeiros, M.1
Velasquez-Jones, L.2
Hernandez, A.M.3
-
169
-
-
85046463589
-
The effect of spironolactone on calcineurin inhibitor induced nephrotoxicity: a multicenter randomized, double-blind, clinical trial (the SPIREN trial)
-
Mortensen, L.A., Thiesson, H.C., Tougaard, B., et al. The effect of spironolactone on calcineurin inhibitor induced nephrotoxicity: a multicenter randomized, double-blind, clinical trial (the SPIREN trial). BMC Nephrol, 19, 2018, 105.
-
(2018)
BMC Nephrol
, vol.19
, pp. 105
-
-
Mortensen, L.A.1
Thiesson, H.C.2
Tougaard, B.3
-
170
-
-
84994430570
-
The effect of spironolactone on acute kidney injury after cardiac surgery: a randomized, placebo-controlled trial
-
Barba-Navarro, R., Tapia-Silva, M., Garza-Garcia, C., et al. The effect of spironolactone on acute kidney injury after cardiac surgery: a randomized, placebo-controlled trial. Am J Kidney Dis 69 (2017), 192–199.
-
(2017)
Am J Kidney Dis
, vol.69
, pp. 192-199
-
-
Barba-Navarro, R.1
Tapia-Silva, M.2
Garza-Garcia, C.3
-
171
-
-
84866559183
-
Angiotensin-converting enzyme inhibition or mineralocorticoid receptor blockade do not affect prevalence of atrial fibrillation in patients undergoing cardiac surgery
-
Pretorius, M., Murray, K.T., Yu, C., et al. Angiotensin-converting enzyme inhibition or mineralocorticoid receptor blockade do not affect prevalence of atrial fibrillation in patients undergoing cardiac surgery. Crit Care Med 40 (2012), 2805–2812.
-
(2012)
Crit Care Med
, vol.40
, pp. 2805-2812
-
-
Pretorius, M.1
Murray, K.T.2
Yu, C.3
-
172
-
-
85083070640
-
The effect of spironolactone on the incidence of contrast-induced nephropathy in patients undergoing cardiac catheterization: study design and rationale
-
Mujtaba, A., Taher, M.A., Hazza, M.A., et al. The effect of spironolactone on the incidence of contrast-induced nephropathy in patients undergoing cardiac catheterization: study design and rationale. Cardiol Ther 7 (2018), 101–106.
-
(2018)
Cardiol Ther
, vol.7
, pp. 101-106
-
-
Mujtaba, A.1
Taher, M.A.2
Hazza, M.A.3
-
173
-
-
34548163060
-
The incidence and implications of aldosterone breakthrough
-
Bomback, A.S., Klemmer, P.J., The incidence and implications of aldosterone breakthrough. Nat Clin Pract Nephrol 3 (2007), 486–492.
-
(2007)
Nat Clin Pract Nephrol
, vol.3
, pp. 486-492
-
-
Bomback, A.S.1
Klemmer, P.J.2
-
174
-
-
0037222490
-
Effectiveness of aldosterone blockade in patients with diabetic nephropathy
-
Sato, A., Hayashi, K., Naruse, M., Saruta, T., Effectiveness of aldosterone blockade in patients with diabetic nephropathy. Hypertension 41 (2003), 64–68.
-
(2003)
Hypertension
, vol.41
, pp. 64-68
-
-
Sato, A.1
Hayashi, K.2
Naruse, M.3
Saruta, T.4
-
175
-
-
12144252958
-
Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate
-
Schjoedt, K.J., Andersen, S., Rossing, P., et al. Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate. Diabetologia 47 (2004), 1936–1939.
-
(2004)
Diabetologia
, vol.47
, pp. 1936-1939
-
-
Schjoedt, K.J.1
Andersen, S.2
Rossing, P.3
-
176
-
-
48949118159
-
Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy
-
Bakris, G., Burgess, E., Weir, M., et al. Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy. Kidney Int 74 (2008), 364–369.
-
(2008)
Kidney Int
, vol.74
, pp. 364-369
-
-
Bakris, G.1
Burgess, E.2
Weir, M.3
-
177
-
-
84885216371
-
Determinants and changes associated with aldosterone breakthrough after angiotensin II receptor blockade in patients with type 2 diabetes with overt nephropathy
-
Moranne, O., Bakris, G., Fafin, C., et al. Determinants and changes associated with aldosterone breakthrough after angiotensin II receptor blockade in patients with type 2 diabetes with overt nephropathy. Clin J Am Soc Nephrol 8 (2013), 1694–1701.
-
(2013)
Clin J Am Soc Nephrol
, vol.8
, pp. 1694-1701
-
-
Moranne, O.1
Bakris, G.2
Fafin, C.3
-
178
-
-
84890086278
-
Long-term effects of addition of mineralocorticoid receptor antagonist to angiotensin II receptor blocker in patients with diabetic nephropathy: a randomized clinical trial
-
Esteghamati, A., Noshad, S., Jarrah, S., et al. Long-term effects of addition of mineralocorticoid receptor antagonist to angiotensin II receptor blocker in patients with diabetic nephropathy: a randomized clinical trial. Nephrol Dial Transplant 28 (2013), 2823–2833.
-
(2013)
Nephrol Dial Transplant
, vol.28
, pp. 2823-2833
-
-
Esteghamati, A.1
Noshad, S.2
Jarrah, S.3
-
179
-
-
84885042198
-
Are hospitalized or ambulatory patients with heart failure treated in accordance with European Society of Cardiology guidelines? Evidence from 12,440 patients of the ESC Heart Failure Long-Term Registry
-
Maggioni, A.P., Anker, S.D., Dahlstrom, U., et al. Are hospitalized or ambulatory patients with heart failure treated in accordance with European Society of Cardiology guidelines? Evidence from 12,440 patients of the ESC Heart Failure Long-Term Registry. Eur J Heart Fail 15 (2013), 1173–1184.
-
(2013)
Eur J Heart Fail
, vol.15
, pp. 1173-1184
-
-
Maggioni, A.P.1
Anker, S.D.2
Dahlstrom, U.3
-
180
-
-
85051228836
-
2018 ESC/ESH guidelines for the management of arterial hypertension
-
Williams, B., Mancia, G., Spiering, W., et al. 2018 ESC/ESH guidelines for the management of arterial hypertension. Eur Heart J 39 (2018), 3021–3104.
-
(2018)
Eur Heart J
, vol.39
, pp. 3021-3104
-
-
Williams, B.1
Mancia, G.2
Spiering, W.3
-
181
-
-
84992027427
-
Hyperkalemia in heart failure
-
Sarwar, C.M., Papadimitriou, L., Pitt, B., et al. Hyperkalemia in heart failure. J Am Coll Cardiol 68 (2016), 1575–1589.
-
(2016)
J Am Coll Cardiol
, vol.68
, pp. 1575-1589
-
-
Sarwar, C.M.1
Papadimitriou, L.2
Pitt, B.3
-
182
-
-
85016571674
-
True rate of mineralocorticoid receptor antagonists-related hyperkalemia in placebo-controlled trials: a meta-analysis
-
Vukadinovic, D., Lavall, D., Vukadinovic, A.N., et al. True rate of mineralocorticoid receptor antagonists-related hyperkalemia in placebo-controlled trials: a meta-analysis. Am Heart J 188 (2017), 99–108.
-
(2017)
Am Heart J
, vol.188
, pp. 99-108
-
-
Vukadinovic, D.1
Lavall, D.2
Vukadinovic, A.N.3
-
183
-
-
77958533631
-
Addition of spironolactone to dual blockade of renin angiotensin system dramatically reduces severe proteinuria in renal transplant patients: an uncontrolled pilot study at 6 months
-
Gonzalez Monte, E., Andres, A., Polanco, N., et al. Addition of spironolactone to dual blockade of renin angiotensin system dramatically reduces severe proteinuria in renal transplant patients: an uncontrolled pilot study at 6 months. Transplant Proc 42 (2010), 2899–2901.
-
(2010)
Transplant Proc
, vol.42
, pp. 2899-2901
-
-
Gonzalez Monte, E.1
Andres, A.2
Polanco, N.3
-
184
-
-
84978903960
-
Safety of eplerenone for kidney-transplant recipients with impaired renal function and receiving cyclosporine A
-
Bertocchio, J.P., Barbe, C., Lavaud, S., et al. Safety of eplerenone for kidney-transplant recipients with impaired renal function and receiving cyclosporine A. PLoS One, 11, 2016, e0153635.
-
(2016)
PLoS One
, vol.11
, pp. e0153635
-
-
Bertocchio, J.P.1
Barbe, C.2
Lavaud, S.3
-
185
-
-
85045836411
-
Incidence, predictors and clinical management of hyperkalaemia in new users of mineralocorticoid receptor antagonists
-
Trevisan, M., de Deco, P., Xu, H., et al. Incidence, predictors and clinical management of hyperkalaemia in new users of mineralocorticoid receptor antagonists. Eur J Heart Fail 20 (2018), 1217–1226.
-
(2018)
Eur J Heart Fail
, vol.20
, pp. 1217-1226
-
-
Trevisan, M.1
de Deco, P.2
Xu, H.3
-
186
-
-
85009986203
-
Characterization of mineralocorticoid receptor antagonist therapy initiation in high-risk patients with heart failure
-
Cooper, L.B., Hammill, B.G., Peterson, E.D., et al. Characterization of mineralocorticoid receptor antagonist therapy initiation in high-risk patients with heart failure. Circ Cardiovasc Qual Outcomes, 10, 2017.
-
(2017)
Circ Cardiovasc Qual Outcomes
, vol.10
-
-
Cooper, L.B.1
Hammill, B.G.2
Peterson, E.D.3
-
187
-
-
84870432435
-
Management of hyperkalaemia consequent to mineralocorticoid-receptor antagonist therapy
-
Roscioni, S.S., de Zeeuw, D., Bakker, S.J., Lambers Heerspink, H.J., Management of hyperkalaemia consequent to mineralocorticoid-receptor antagonist therapy. Nat Rev Nephrol 8 (2012), 691–699.
-
(2012)
Nat Rev Nephrol
, vol.8
, pp. 691-699
-
-
Roscioni, S.S.1
de Zeeuw, D.2
Bakker, S.J.3
Lambers Heerspink, H.J.4
-
188
-
-
84920982556
-
Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors
-
Weir, M.R., Bakris, G.L., Bushinsky, D.A., et al. Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors. N Engl J Med 372 (2015), 211–221.
-
(2015)
N Engl J Med
, vol.372
, pp. 211-221
-
-
Weir, M.R.1
Bakris, G.L.2
Bushinsky, D.A.3
-
189
-
-
85051100646
-
Long-term effects of patiromer for hyperkalaemia treatment in patients with mild heart failure and diabetic nephropathy on angiotensin-converting enzymes/angiotensin receptor blockers: results from AMETHYST-DN
-
Pitt, B., Bakris, G.L., Weir, M.R., et al. Long-term effects of patiromer for hyperkalaemia treatment in patients with mild heart failure and diabetic nephropathy on angiotensin-converting enzymes/angiotensin receptor blockers: results from AMETHYST-DN. ESC Heart Fail 5 (2018), 592–602.
-
(2018)
ESC Heart Fail
, vol.5
, pp. 592-602
-
-
Pitt, B.1
Bakris, G.L.2
Weir, M.R.3
-
190
-
-
85038858546
-
Revisiting RAAS blockade in CKD with newer potassium-binding drugs
-
Georgianos, P.I., Agarwal, R., Revisiting RAAS blockade in CKD with newer potassium-binding drugs. Kidney Int 93 (2018), 325–334.
-
(2018)
Kidney Int
, vol.93
, pp. 325-334
-
-
Georgianos, P.I.1
Agarwal, R.2
-
191
-
-
84920973726
-
Sodium zirconium cyclosilicate in hyperkalemia
-
Packham, D.K., Rasmussen, H.S., Lavin, P.T., et al. Sodium zirconium cyclosilicate in hyperkalemia. N Engl J Med 372 (2015), 222–231.
-
(2015)
N Engl J Med
, vol.372
, pp. 222-231
-
-
Packham, D.K.1
Rasmussen, H.S.2
Lavin, P.T.3
-
192
-
-
84914703676
-
Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: the HARMONIZE randomized clinical trial
-
Kosiborod, M., Rasmussen, H.S., Lavin, P., et al. Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: the HARMONIZE randomized clinical trial. JAMA 312 (2014), 2223–2233.
-
(2014)
JAMA
, vol.312
, pp. 2223-2233
-
-
Kosiborod, M.1
Rasmussen, H.S.2
Lavin, P.3
-
193
-
-
84941206302
-
New potassium binders for the treatment of hyperkalemia: current data and opportunities for the future
-
Pitt, B., Bakris, G.L., New potassium binders for the treatment of hyperkalemia: current data and opportunities for the future. Hypertension 66 (2015), 731–738.
-
(2015)
Hypertension
, vol.66
, pp. 731-738
-
-
Pitt, B.1
Bakris, G.L.2
-
194
-
-
84904267679
-
Finerenone, a novel selective nonsteroidal mineralocorticoid receptor antagonist protects from rat cardiorenal injury
-
Kolkhof, P., Delbeck, M., Kretschmer, A., et al. Finerenone, a novel selective nonsteroidal mineralocorticoid receptor antagonist protects from rat cardiorenal injury. J Cardiovasc Pharmacol 64 (2014), 69–78.
-
(2014)
J Cardiovasc Pharmacol
, vol.64
, pp. 69-78
-
-
Kolkhof, P.1
Delbeck, M.2
Kretschmer, A.3
-
195
-
-
84901272015
-
PF-03882845, a non-steroidal mineralocorticoid receptor antagonist, prevents renal injury with reduced risk of hyperkalemia in an animal model of nephropathy
-
Orena, S., Maurer, T.S., She, L., et al. PF-03882845, a non-steroidal mineralocorticoid receptor antagonist, prevents renal injury with reduced risk of hyperkalemia in an animal model of nephropathy. Front Pharmacol, 4, 2013, 115.
-
(2013)
Front Pharmacol
, vol.4
, pp. 115
-
-
Orena, S.1
Maurer, T.S.2
She, L.3
-
196
-
-
84948958950
-
Finerenone: third-generation mineralocorticoid receptor antagonist for the treatment of heart failure and diabetic kidney disease
-
Liu, L.C., Schutte, E., Gansevoort, R.T., et al. Finerenone: third-generation mineralocorticoid receptor antagonist for the treatment of heart failure and diabetic kidney disease. Expert Opin Investig Drugs 24 (2015), 1123–1135.
-
(2015)
Expert Opin Investig Drugs
, vol.24
, pp. 1123-1135
-
-
Liu, L.C.1
Schutte, E.2
Gansevoort, R.T.3
-
197
-
-
85020624973
-
Steroidal and novel non-steroidal mineralocorticoid receptor antagonists in heart failure and cardiorenal diseases: comparison at bench and bedside
-
Kolkhof, P., Jaisser, F., Kim, S.Y., et al. Steroidal and novel non-steroidal mineralocorticoid receptor antagonists in heart failure and cardiorenal diseases: comparison at bench and bedside. Handb Exp Pharmacol 243 (2017), 271–305.
-
(2017)
Handb Exp Pharmacol
, vol.243
, pp. 271-305
-
-
Kolkhof, P.1
Jaisser, F.2
Kim, S.Y.3
|