Deletion of mineralocorticoid receptors in smooth muscle cells blunts renal vascular resistance following acute cyclosporine administration

Kidney International

Volumn 89, Issue 2, 2016, Pages 354-362

  Amador, Cristian A ^a   Bertocchio, Jean Philippe ^a,b   Andre Gregoire, Gwennan ^a   Placier, Sandrine ^c   Duong Van Huyen, Jean Paul ^d   El Moghrabi, Soumaya ^a   Berger, Stefan ^e   Warnock, David G ^f   Chatziantoniou, Christos ^c   Jaffe, Iris Z ^g   Rieu, Philippe ^b   Jaisser, Frederic ^a  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b REIMS UNIVERSITY HOSPITAL   (France)

^c HÔPITAL TENON   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^g TUFTS MEDICAL CENTER   (United States)

Author keywords

acute kidney injury; aldosterone; calcineurin inhibitors; nephrotoxicity

Indexed keywords

BIOLOGICAL MARKER; CALCIUM CHANNEL L TYPE; CREATININE; CYCLOSPORIN A; MINERALOCORTICOID RECEPTOR; MUSCLE PROTEIN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; UNCLASSIFIED DRUG; UREA; VASCULAR SMOOTH MUSCLE CONTRACTILE PROTEIN; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VACUOLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENDOTHELIUM; ENDOTHELIUM CELL; FEMALE; GENE DELETION; GENE INACTIVATION; GENE OVEREXPRESSION; IN VIVO STUDY; KIDNEY BLOOD FLOW; KIDNEY VASCULAR RESISTANCE; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE CELL; UREA BLOOD LEVEL; ANIMAL; C57BL MOUSE; KIDNEY DISEASES; METABOLISM; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM; VASCULAR RESISTANCE; VASCULAR SMOOTH MUSCLE;

ANIMALS; CALCIUM CHANNELS, L-TYPE; CYCLOSPORINE; ENDOTHELIUM, VASCULAR; FEMALE; GENE KNOCKOUT TECHNIQUES; IMMUNOSUPPRESSIVE AGENTS; KIDNEY DISEASES; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, MINERALOCORTICOID; VASCULAR RESISTANCE;

EID: 84942683836     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2015.312     Document Type: Article

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