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Volumn 126, Issue 1, 2014, Pages 16-24

Local mineralocorticoid receptor activation and the role of rac1 in obesity-related diabetic kidney disease

Author keywords

Diabetic nephropathy; Inflammatory cytokines; Mineralocorticoid receptor; Obesity; Rac1

Indexed keywords

ALDOSTERONE; EHT 1864; GLUCOSE; GLUTATHIONE TRANSFERASE; HYDROLASE INHIBITOR; MINERALOCORTICOID RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; RAC1 PROTEIN; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; CCL2 PROTEIN, MOUSE; PYRONE DERIVATIVE; QUINOLINE DERIVATIVE; MANNITOL; PROTEIN INHIBITOR;

EID: 84895577445     PISSN: None     EISSN: 16602129     Source Type: Journal    
DOI: 10.1159/000358758     Document Type: Article
Times cited : (35)

References (35)
  • 2
    • 79951558318 scopus 로고    scopus 로고
    • National regional and global trends in body-mass index since 1980 systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants
    • Finucane MM, Stevens G, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, et al: National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Lancet 2011; 377: 557-567.
    • (2011) Lancet , vol.377 , pp. 557-567
    • Finucane, M.M.1    Stevens, G.2    Cowan, M.J.3    Danaei, G.4    Lin, J.K.5    Paciorek, C.J.6
  • 4
    • 41149145963 scopus 로고    scopus 로고
    • Albuminuria: A great risk marker, but an underestimated target in diabetes
    • De Zeeuw D, Raz I: Albuminuria: a great risk marker, but an underestimated target in diabetes. Diabetes Care 2008; 31(suppl 2):S190-S193.
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL. 2
    • De Zeeuw, D.1    Raz, I.2
  • 6
    • 35848952953 scopus 로고    scopus 로고
    • Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: Role of oxidative stress
    • DOI 10.1161/HYPERTENSIONAHA.107.091058
    • Nagase M, Matsui H, Shibata S, Gotoda T, Fujita T: Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress. Hypertension 2007; 50: 877-883. (Pubitemid 350287529)
    • (2007) Hypertension , vol.50 , Issue.5 , pp. 877-883
    • Nagase, M.1    Matsui, H.2    Shibata, S.3    Gotoda, T.4    Fujita, T.5
  • 7
    • 33846443625 scopus 로고    scopus 로고
    • Podocyte as the target for aldosterone: Roles of oxidative stress and Sgk1
    • DOI 10.1161/01.HYP.0000255636.11931.a2, PII 0000426820070200000021
    • Shibata S, Nagase M, Yoshida S, Kawachi H, Fujita T: Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1. Hypertension 2007; 49: 355-364. (Pubitemid 46143013)
    • (2007) Hypertension , vol.49 , Issue.2 , pp. 355-364
    • Shibata, S.1    Nagase, M.2    Yoshida, S.3    Kawachi, H.4    Fujita, T.5
  • 8
    • 84860367978 scopus 로고    scopus 로고
    • Aldosterone blockade and the mineralocorticoid receptor in the management of chronic kidney disease: Current concepts and emerging treatment paradigms
    • Shavit L, Lifschitz MD, Epstein M: Aldosterone blockade and the mineralocorticoid receptor in the management of chronic kidney disease: current concepts and emerging treatment paradigms. Kidney Int 2012; 81: 955-968.
    • (2012) Kidney Int , vol.81 , pp. 955-968
    • Shavit, L.1    Lifschitz, M.D.2    Epstein, M.3
  • 10
    • 77956237924 scopus 로고    scopus 로고
    • Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats
    • Kawarazaki H, Ando K, Nagae A, Fujita M, Matsui H, Fujita T: Mineralocorticoid receptor activation contributes to salt-induced hypertension and renal injury in prepubertal Dahl salt-sensitive rats. Nephrol Dial Transplant 2010; 25: 2879-2889.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2879-2889
    • Kawarazaki, H.1    Ando, K.2    Nagae, A.3    Fujita, M.4    Matsui, H.5    Fujita, T.6
  • 11
    • 33845238078 scopus 로고    scopus 로고
    • Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: Possible contribution of fat-derived factors
    • DOI 10.1681/ASN.2006080944
    • Nagase M, Yoshida S, Shibata S, Nagase T, Gotoda T, Ando K, et al: Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: possible contribution of fat-derived factors. J Am Soc Nephrol 2006; 17: 3438-3446. (Pubitemid 44865286)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.12 , pp. 3438-3446
    • Nagase, M.1    Yoshida, S.2    Shibata, S.3    Nagase, T.4    Gotoda, T.5    Ando, K.6    Fujita, T.7
  • 13
    • 57349168398 scopus 로고    scopus 로고
    • Modification of mineralocorticoid receptor function by Rac1 GTPase: Implication in proteinuric kidney disease
    • Shibata S, Nagase M, Yoshida S, Kawarazaki W, Kurihara H, Tanaka H, et al: Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease. Nat Med 2008; 14: 1370-1376.
    • (2008) Nat Med , vol.14 , pp. 1370-1376
    • Shibata, S.1    Nagase, M.2    Yoshida, S.3    Kawarazaki, W.4    Kurihara, H.5    Tanaka, H.6
  • 14
    • 84881245920 scopus 로고    scopus 로고
    • ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling
    • Gee HY, Saisawat P, Ashraf S, Hurd TW, Vega-Warner V, Fang H, et al: ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling. J Clin Invest 2013; 123: 3243-3253.
    • (2013) J Clin Invest , vol.123 , pp. 3243-3253
    • Gee, H.Y.1    Saisawat, P.2    Ashraf, S.3    Hurd, T.W.4    Vega-Warner, V.5    Fang, H.6
  • 15
    • 84856113013 scopus 로고    scopus 로고
    • Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes: Role of small GTPase Rac1
    • Nagase M, Ayuzawa N, Kawarazaki W, Ishizawa K, Ueda K, Yoshida S, et al: Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes: role of small GTPase Rac1. Hypertension 2012; 59: 500-506.
    • (2012) Hypertension , vol.59 , pp. 500-506
    • Nagase, M.1    Ayuzawa, N.2    Kawarazaki, W.3    Ishizawa, K.4    Ueda, K.5    Yoshida, S.6
  • 16
    • 44249108994 scopus 로고    scopus 로고
    • Superoxide destabilization of β-catenin augments apoptosis of high-glucose-stressed mesangial cells
    • DOI 10.1210/en.2007-1372
    • Lin CL, Wang JY, Ko JY, Surendran K, Huang YT, Kuo YH, et al: Superoxide destabilization of beta-catenin augments apoptosis of highglucose-stressed mesangial cells. Endocrinology 2008; 149: 2934-2942. (Pubitemid 351724526)
    • (2008) Endocrinology , vol.149 , Issue.6 , pp. 2934-2942
    • Lin, C.-L.1    Wang, J.-Y.2    Ko, J.-Y.3    Surendran, K.4    Huang, Y.-T.5    Kuo, Y.-H.6    Wang, F.-S.7
  • 17
    • 67649118398 scopus 로고    scopus 로고
    • Rac1 is required for cardiomyocyte apoptosis during hyperglycemia
    • Shen E, Li Y, Li Y, Shan L, Zhu H, Feng Q, et al: Rac1 is required for cardiomyocyte apoptosis during hyperglycemia. Diabetes 2009; 58: 2386-2395.
    • (2009) Diabetes , vol.58 , pp. 2386-2395
    • Shen, E.1    Li, Y.2    Li, Y.3    Shan, L.4    Zhu, H.5    Feng, Q.6
  • 20
    • 33645361420 scopus 로고    scopus 로고
    • Glomerular changes in the KK-Ay/Ta mouse: A possible model for human type 2 diabetic nephropathy
    • Ito T, Tanimoto M, Yamada K, Kaneko S, Matsumoto M, Obayashi K, et al: Glomerular changes in the KK-Ay/Ta mouse: a possible model for human type 2 diabetic nephropathy. Nephrology 2006; 11: 29-35.
    • (2006) Nephrology , vol.11 , pp. 29-35
    • Ito, T.1    Tanimoto, M.2    Yamada, K.3    Kaneko, S.4    Matsumoto, M.5    Obayashi, K.6
  • 21
    • 42549105123 scopus 로고    scopus 로고
    • Podocyte injury induced by albumin overload in vivo and in vitro: Involvement of TGF-beta and p38 MAPK
    • DOI 10.1159/000124236
    • Yoshida S, Nagase M, Shibata S, Fujita T: Podocyte injury induced by albumin overload in vivo and in vitro: involvement of TGF-beta and p38 MAPK. Nephron Exp Nephrol 2008; 108:e57-e68. (Pubitemid 351592585)
    • (2008) Nephron - Experimental Nephrology , vol.108 , Issue.3
    • Yoshida, S.1    Nagase, M.2    Shibata, S.3    Fujita, T.4
  • 22
    • 79960972766 scopus 로고    scopus 로고
    • Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway
    • Shibata S, Mu S, Kawarazaki H, Muraoka K, Ishizawa K, Yoshida S, et al: Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway. J Clin Invest 2011; 121: 3233-3243.
    • (2011) J Clin Invest , vol.121 , pp. 3233-3243
    • Shibata, S.1    Mu, S.2    Kawarazaki, H.3    Muraoka, K.4    Ishizawa, K.5    Yoshida, S.6
  • 23
    • 84861832781 scopus 로고    scopus 로고
    • Angiotensin II-and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation
    • Kawarazaki W, Nagase M, Yoshida S, Takeuchi M, Ishizawa K, Ayuzawa N, et al: Angiotensin II-and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation. J Am Soc Nephrol 2012; 23: 997-1007.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 997-1007
    • Kawarazaki, W.1    Nagase, M.2    Yoshida, S.3    Takeuchi, M.4    Ishizawa, K.5    Ayuzawa, N.6
  • 25
    • 70350710165 scopus 로고    scopus 로고
    • Activation of local aldosterone system within podocytes is involved in apoptosis under diabetic conditions
    • Lee SH, Yoo TH, Nam BY, Kim DK, Li JJ, Jung DS, et al: Activation of local aldosterone system within podocytes is involved in apoptosis under diabetic conditions. Am J Physiol Renal Physiol 2009; 297:F1381-F1390.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Lee, S.H.1    Yoo, T.H.2    Nam, B.Y.3    Kim, D.K.4    Li, J.J.5    Jung, D.S.6
  • 26
    • 33644695681 scopus 로고    scopus 로고
    • Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion
    • DOI 10.2337/diabetes.54.12.3523
    • Kowluru A, Veluthakal R: Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion. Diabetes 2005; 54: 3523-3529. (Pubitemid 43334345)
    • (2005) Diabetes , vol.54 , Issue.12 , pp. 3523-3529
    • Kowluru, A.1    Veluthakal, R.2
  • 27
    • 30944456936 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice
    • DOI 10.1038/sj.ki.5000014, PII 5000014
    • Chow FY, Nikolic-Paterson DJ, Ozols E, Atkins RC, Rollin BJ, Tesch GH: Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice. Kidney Int 2006; 69: 73-80. (Pubitemid 43117741)
    • (2006) Kidney International , vol.69 , Issue.1 , pp. 73-80
    • Chow, F.Y.1    Nikolic-Paterson, D.J.2    Ozols, E.3    Atkins, R.C.4    Rollin, B.J.5    Tesch, G.H.6
  • 29
    • 2342454479 scopus 로고    scopus 로고
    • Aldosterone, mineralocorticoid receptors and vascular inflammation
    • DOI 10.1016/j.mce.2003.10.054, PII S0303720703004143
    • Funder JW: Aldosterone, mineralocorticoid receptors and vascular inflammation. Mol Cell Endocrinol 2004; 217: 263-269. (Pubitemid 38596652)
    • (2004) Molecular and Cellular Endocrinology , vol.217 , Issue.1-2 , pp. 263-269
    • Funder, J.W.1
  • 31
    • 70350704815 scopus 로고    scopus 로고
    • Mesangial cell-derived factors alter monocyte activation and function through inflammatory pathways: Possible pathogenic role in diabetic nephropathy
    • Min D, Lyons JG, Bonner J, Twigg SM, Yue DK, McLennan SV: Mesangial cell-derived factors alter monocyte activation and function through inflammatory pathways: possible pathogenic role in diabetic nephropathy. Am J Physiol Renal Physiol 2009; 297:F1229-F1237.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Min, D.1    Lyons, J.G.2    Bonner, J.3    Twigg, S.M.4    Yue, D.K.5    McLennan, S.V.6
  • 32
    • 33744954417 scopus 로고    scopus 로고
    • Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy
    • DOI 10.1210/jc.2005-1718
    • Takebayashi K, Matsumoto S, Aso Y, Inukai T: Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy. J Clin Endocrinol Metab 2006; 91: 2214-2217. (Pubitemid 43855008)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.6 , pp. 2214-2217
    • Takebayashi, K.1    Matsumoto, S.2    Aso, Y.3    Inukai, T.4
  • 35
    • 84873106278 scopus 로고    scopus 로고
    • Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease
    • Nagase M, Fujita T: Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease. Nat Rev Nephrol 2013; 9: 86-98.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 86-98
    • Nagase, M.1    Fujita, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.