-
1
-
-
34047121150
-
Renin-angiotensin system and cardiovascular risk
-
Schmieder RE, Hilgers KF, Schlaich MP et al. Renin-angiotensin system and cardiovascular risk. Lancet 2007; 369: 1208-1219
-
(2007)
Lancet
, vol.369
, pp. 1208-1219
-
-
Schmieder, R.E.1
Hilgers, K.F.2
Schlaich, M.P.3
-
2
-
-
0037161021
-
Angiotensin blockade for hypertension: A promise fulfilled
-
Brunner HR, Gavras H. Angiotensin blockade for hypertension: a promise fulfilled. Lancet 2000; 359: 990-992
-
(2000)
Lancet
, vol.359
, pp. 990-992
-
-
Brunner, H.R.1
Gavras, H.2
-
3
-
-
0028365310
-
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
-
Griendling KK, Minieri CA, Ollerenshaw JD et al. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 1994; 74: 1141-1148
-
(1994)
Circ Res
, vol.74
, pp. 1141-1148
-
-
Griendling, K.K.1
Minieri, C.A.2
Ollerenshaw, J.D.3
-
4
-
-
0032572719
-
-/- mice reveals a role for chemokines in the initiation of atherosclerosis
-
-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 1998; 394: 894-897
-
(1998)
Nature
, vol.394
, pp. 894-897
-
-
Boring, L.1
Gosling, J.2
Cleary, M.3
-
5
-
-
0033046999
-
Strategies to achieve coronary arterial plaque stabilization
-
Rabbani R, Topol EJ. Strategies to achieve coronary arterial plaque stabilization. Cardiovasc Res 1999; 41: 402-417
-
(1999)
Cardiovasc Res
, vol.41
, pp. 402-417
-
-
Rabbani, R.1
Topol, E.J.2
-
6
-
-
24144502074
-
Role of reactive oxygen species in angiotensin II-mediated renal growth, differentiation, and apoptosis
-
Wolf G. Role of reactive oxygen species in angiotensin II-mediated renal growth, differentiation, and apoptosis. Antioxid Redox Signal 2005; 7: 1337-1345
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1337-1345
-
-
Wolf, G.1
-
7
-
-
34047247353
-
The renin-angiotensin system and diabetic nephropathy
-
Gurley SB, Coffman TM. The renin-angiotensin system and diabetic nephropathy. Semin Nephrol 2007; 27: 144-152
-
(2007)
Semin Nephrol
, vol.27
, pp. 144-152
-
-
Gurley, S.B.1
Coffman, T.M.2
-
8
-
-
4544374648
-
Prevention of renal fibrosis by spironolactone in mice with complete unilateral ureteral obstruction
-
Trachtman H, Weiser AC, Valderrama E et al. Prevention of renal fibrosis by spironolactone in mice with complete unilateral ureteral obstruction. J Urol 2004; 172(Suppl 4): S1590-S1594
-
(2004)
J Urol
, vol.172
, Issue.SUPPL. 4
-
-
Trachtman, H.1
Weiser, A.C.2
Valderrama, E.3
-
9
-
-
6444245944
-
Therapeutic benefit of spironolactone in experimental cyclosporine A nephrotoxicity
-
Feria I, Pichardo I, Juarez P et al. Therapeutic benefit of spironolactone in experimental cyclosporine A nephrotoxicity. Kidney Int 2003; 63: 43-52
-
(2003)
Kidney Int
, vol.63
, pp. 43-52
-
-
Feria, I.1
Pichardo, I.2
Juarez, P.3
-
10
-
-
0242366540
-
Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats
-
Blasi ER, Rocha R, Rudolph AE et al. Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats. Kidney Int 2003; 63: 1791-1800
-
(2003)
Kidney Int
, vol.63
, pp. 1791-1800
-
-
Blasi, E.R.1
Rocha, R.2
Rudolph, A.E.3
-
11
-
-
4644245230
-
Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats
-
Fujisawa G, Okada K, Muto S et al. Spironolactone prevents early renal injury in streptozotocin-induced diabetic rats. Kidney Int 2004; 66: 1493-1502
-
(2004)
Kidney Int
, vol.66
, pp. 1493-1502
-
-
Fujisawa, G.1
Okada, K.2
Muto, S.3
-
12
-
-
0034946204
-
Reversal of cardiac and renal fibrosis by pirfenidine and spironolactone in streptozotocin-diabetic rats
-
Miric G, Dallemagne C, Endre Z. Reversal of cardiac and renal fibrosis by pirfenidine and spironolactone in streptozotocin-diabetic rats. Br J Pharmacol 2001; 133: 687-694
-
(2001)
Br J Pharmacol
, vol.133
, pp. 687-694
-
-
Miric, G.1
Dallemagne, C.2
Endre, Z.3
-
13
-
-
5444239060
-
Spironolactone and angiotensin receptor blocker in nondiabetic renal diseases
-
Nitta K, Uchida K, Nihei H. Spironolactone and angiotensin receptor blocker in nondiabetic renal diseases. Am J Med 2004; 117: 444-445
-
(2004)
Am J Med
, vol.117
, pp. 444-445
-
-
Nitta, K.1
Uchida, K.2
Nihei, H.3
-
14
-
-
33750264932
-
Use of antagonists of aldosterone in patients with chronic kidney disease: Potential advantages and risks
-
Campese VM, Park J. Use of antagonists of aldosterone in patients with chronic kidney disease: potential advantages and risks. J Hypertens 2006; 24: 2157-2159
-
(2006)
J Hypertens
, vol.24
, pp. 2157-2159
-
-
Campese, V.M.1
Park, J.2
-
15
-
-
0037222490
-
Effectiveness of aldosterone blockade in patients with diabetic nephropathy
-
Sato A, Hayashi K, Naruse M et al. Effectiveness of aldosterone blockade in patients with diabetic nephropathy. Hypertension 2003; 41: 64-68
-
(2003)
Hypertension
, vol.41
, pp. 64-68
-
-
Sato, A.1
Hayashi, K.2
Naruse, M.3
-
16
-
-
13244298395
-
Antiproteinuric effects of mineralocorticoid receptor blockade in patients with chronic renal disease
-
Sato A, Hayashi K, Saruta T. Antiproteinuric effects of mineralocorticoid receptor blockade in patients with chronic renal disease. Am J Hypertens 2005; 18: 44-49
-
(2005)
Am J Hypertens
, vol.18
, pp. 44-49
-
-
Sato, A.1
Hayashi, K.2
Saruta, T.3
-
17
-
-
13244267053
-
Urinary concentration of transforming growth factor-beta-inducible gene-h3(beta ig-h3) in patients with type 2 diabetes mellitus
-
Cha DR, Kim IS, Kang YS et al. Urinary concentration of transforming growth factor-beta-inducible gene-h3(beta ig-h3) in patients with type 2 diabetes mellitus. Diabet Med 2005; 22: 14-20
-
(2005)
Diabet Med
, vol.22
, pp. 14-20
-
-
Cha, D.R.1
Kim, I.S.2
Kang, Y.S.3
-
18
-
-
24344451692
-
Regression of glomerulosclerosis with high-dose angiotensin inhibition is linked to decreased plasminogen activator inhibitor-1
-
Ma LJ, Nakamura S, Aldigier JC et al. Regression of glomerulosclerosis with high-dose angiotensin inhibition is linked to decreased plasminogen activator inhibitor-1. J Am Soc Nephrol 2005; 16: 966-976
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 966-976
-
-
Ma, L.J.1
Nakamura, S.2
Aldigier, J.C.3
-
19
-
-
7344224952
-
Renal expression of transforming growth factor-β-inducible gene-h3 (ßig-h3) in normal and diabetic rats
-
Gilbert RE, Wilkinson BJL, Johnson DW et al. Renal expression of transforming growth factor-β-inducible gene-h3 (ßig-h3) in normal and diabetic rats. Kidney Int 1998; 54: 1052-1062
-
(1998)
Kidney Int
, vol.54
, pp. 1052-1062
-
-
Gilbert, R.E.1
Wilkinson, B.J.L.2
Johnson, D.W.3
-
20
-
-
0032921738
-
Role of aldosterone in renal vascular injury in stroke-prone hypertensive rats
-
Rocha R, Chander PN, Zuckerman A et al. Role of aldosterone in renal vascular injury in stroke-prone hypertensive rats. Hypertension 1999; 33: 232-237
-
(1999)
Hypertension
, vol.33
, pp. 232-237
-
-
Rocha, R.1
Chander, P.N.2
Zuckerman, A.3
-
21
-
-
0242366540
-
Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats
-
Blasi ER, Rocha R, Rudolph AE et al. Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats. Kidney Int 2003; 63: 1791-1800
-
(2003)
Kidney Int
, vol.63
, pp. 1791-1800
-
-
Blasi, E.R.1
Rocha, R.2
Rudolph, A.E.3
-
22
-
-
6444245944
-
Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity
-
Feria I, Pichardo I, Juarez P et al. Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity. Kidney Int 2003; 63: 43-52
-
(2003)
Kidney Int
, vol.63
, pp. 43-52
-
-
Feria, I.1
Pichardo, I.2
Juarez, P.3
-
23
-
-
1842474802
-
Aldosterone antagonism ameliorates proteinuria and nephrosclerosis independent of glomerular dynamics in L-NAME/SHR model
-
Zhou X, Ono H, Ono Y et al. Aldosterone antagonism ameliorates proteinuria and nephrosclerosis independent of glomerular dynamics in L-NAME/SHR model. Am J Nephrol 2004; 24: 242-249
-
(2004)
Am J Nephrol
, vol.24
, pp. 242-249
-
-
Zhou, X.1
Ono, H.2
Ono, Y.3
-
24
-
-
0033849916
-
Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo
-
Brown NJ, Nakamura S, Ma L. Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo. Kidney Int 2000; 58: 1219-1227
-
(2000)
Kidney Int
, vol.58
, pp. 1219-1227
-
-
Brown, N.J.1
Nakamura, S.2
Ma, L.3
-
25
-
-
20544465842
-
Antagonists of aldosterone and proteinuria in patients with CKD: An uncontrolled pilot study
-
Bianchi S, Bigazzi R, Campese VM. Antagonists of aldosterone and proteinuria in patients with CKD: an uncontrolled pilot study. Am J Kidney Dis 2005; 46: 45-51
-
(2005)
Am J Kidney Dis
, vol.46
, pp. 45-51
-
-
Bianchi, S.1
Bigazzi, R.2
Campese, V.M.3
-
26
-
-
24144495285
-
Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: A randomized, double-masked, cross-over study
-
Rossing K, Schjoedt KJ, Smidt UM et al. Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: a randomized, double-masked, cross-over study. Diabetes Care 2005; 28: 2106-2112
-
(2005)
Diabetes Care
, vol.28
, pp. 2106-2112
-
-
Rossing, K.1
Schjoedt, K.J.2
Smidt, U.M.3
-
27
-
-
32844467281
-
Beneficial impact of spironolactone in diabetic nephropathy
-
Schjoedt KJ, Rossing K, Juhl TR et al. Beneficial impact of spironolactone in diabetic nephropathy. Kidney Int 2005; 68: 2829-2836
-
(2005)
Kidney Int
, vol.68
, pp. 2829-2836
-
-
Schjoedt, K.J.1
Rossing, K.2
Juhl, T.R.3
-
28
-
-
33745683630
-
Spironolactone ameliorates renal injury and connective tissue growth factor expression in type II diabetic rats
-
Han KH, Kang YS, Han SY. Spironolactone ameliorates renal injury and connective tissue growth factor expression in type II diabetic rats. Kidney Int 2006; 70: 111-120
-
(2006)
Kidney Int
, vol.70
, pp. 111-120
-
-
Han, K.H.1
Kang, Y.S.2
Han, S.Y.3
-
29
-
-
33646366660
-
Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats
-
Han SY, Kim CH, Kim HS. Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. J Am Soc Nephrol 2006; 17: 1362-1372
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1362-1372
-
-
Han, S.Y.1
Kim, C.H.2
Kim, H.S.3
-
30
-
-
33744955658
-
Combination therapy with aldosterone blockade and renin-angiotensin inhibitors confers organ protection
-
Sato A, Saruta T, Funder JW. Combination therapy with aldosterone blockade and renin-angiotensin inhibitors confers organ protection. Hypertens Res 2006; 29: 211-216
-
(2006)
Hypertens Res
, vol.29
, pp. 211-216
-
-
Sato, A.1
Saruta, T.2
Funder, J.W.3
-
31
-
-
34447509674
-
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney
-
Onozato ML, Tojo A, Kobayashi N et al. Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney. Nephrol Dial Transplant 2007; 22: 1314-1322
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 1314-1322
-
-
Onozato, M.L.1
Tojo, A.2
Kobayashi, N.3
-
32
-
-
33847203614
-
Effect of combining ACE inhibition with aldosterone blockade on proteinuria and renal damage in experimental nephrosis
-
Kramer AB, van der Meulen EF, Hamming I et al. Effect of combining ACE inhibition with aldosterone blockade on proteinuria and renal damage in experimental nephrosis. Kidney Int 2007; 71: 417-424
-
(2007)
Kidney Int
, vol.71
, pp. 417-424
-
-
Kramer, A.B.1
van der Meulen, E.F.2
Hamming, I.3
-
33
-
-
33750274950
-
Spironolactone in type 2 diabetic nephropathy: Effects on proteinuria, blood pressure and renal function
-
van den Meiracker AH, Baggen RG, Pauli S. Spironolactone in type 2 diabetic nephropathy: effects on proteinuria, blood pressure and renal function. J Hypertens 2006; 24: 2285-2292
-
(2006)
J Hypertens
, vol.24
, pp. 2285-2292
-
-
van den Meiracker, A.H.1
Baggen, R.G.2
Pauli, S.3
-
34
-
-
33746566456
-
Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy
-
Schjoedt KJ, Rossing K, Juhl TR. Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy. Kidney Int 2006; 70: 536-542
-
(2006)
Kidney Int
, vol.70
, pp. 536-542
-
-
Schjoedt, K.J.1
Rossing, K.2
Juhl, T.R.3
-
35
-
-
2342559832
-
The effect of spironolactone, cilazapril and their combination on albuminuria in patients with hypertension and diabetic nephropathy is independent of blood pressure reduction: A randomized controlled study
-
Rachmani R, Slavachevsky I, Amit M. The effect of spironolactone, cilazapril and their combination on albuminuria in patients with hypertension and diabetic nephropathy is independent of blood pressure reduction: a randomized controlled study. Diabet Med 2004; 21: 471-475
-
(2004)
Diabet Med
, vol.21
, pp. 471-475
-
-
Rachmani, R.1
Slavachevsky, I.2
Amit, M.3
-
36
-
-
33744954417
-
Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy
-
Takebayashi K, Matsumoto S, Aso Y et al. Aldosterone blockade attenuates urinary monocyte chemoattractant protein-1 and oxidative stress in patients with type 2 diabetes complicated by diabetic nephropathy. J Clin Endocrinol Metab 2006; 91: 2214-2217
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2214-2217
-
-
Takebayashi, K.1
Matsumoto, S.2
Aso, Y.3
-
38
-
-
33751236177
-
Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus
-
Guo C, Martinez-Vaquez D, Mendez GP et al. Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Endocrinology 2006; 147: 5363-5373
-
(2006)
Endocrinology
, vol.147
, pp. 5363-5373
-
-
Guo, C.1
Martinez-Vaquez, D.2
Mendez, G.P.3
-
39
-
-
34047100847
-
Aldosterone up-regulates production of plasminogen activator inhibitor-1 by renal mesangial cells
-
Yuan J, Jia R, Bao Y. Aldosterone up-regulates production of plasminogen activator inhibitor-1 by renal mesangial cells. J Biochem Mol Biol 2007; 40: 180-188
-
(2007)
J Biochem Mol Biol
, vol.40
, pp. 180-188
-
-
Yuan, J.1
Jia, R.2
Bao, Y.3
-
40
-
-
34548513414
-
The effect of spironolactone on circulating adipocytokines in patients with type 2 diabetes mellitus complicated by diabetic nephropathy
-
Matsumoto S, Takabayashi K, Aso Y. The effect of spironolactone on circulating adipocytokines in patients with type 2 diabetes mellitus complicated by diabetic nephropathy. Metabolism 2006; 55: 1645-1652
-
(2006)
Metabolism
, vol.55
, pp. 1645-1652
-
-
Matsumoto, S.1
Takabayashi, K.2
Aso, Y.3
-
41
-
-
0034642827
-
Angiotensin-converting enzyme inhibitor-associated elevations in serum creatinine: Is this a cause for concern?
-
Bakris GL, Weir MR. Angiotensin-converting enzyme inhibitor-associated elevations in serum creatinine: is this a cause for concern? Arch Intern Med 2000; 160: 685-693
-
(2000)
Arch Intern Med
, vol.160
, pp. 685-693
-
-
Bakris, G.L.1
Weir, M.R.2
-
42
-
-
12144252958
-
Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate
-
Schjoedt KJ, Andersen S, Rossing P et al. Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate. Diabetologia 2004; 47: 1936-1939
-
(2004)
Diabetologia
, vol.47
, pp. 1936-1939
-
-
Schjoedt, K.J.1
Andersen, S.2
Rossing, P.3
|